Head of the group
Grith Lykke Sørensen
Professor, PhD, DMSci
Syddansk Universitet
Department of Molecular Medicine
Cancer and Inflammation Research Unit
Campusvej 55
5230, Odense M
+45 21356098
glsorensen@healh.sdu.dk
https://www.sdu.dk/ansat/glsorensen
Work/Research interests
The research comprises the investigations of innate immunity and matrix biology. The innate immunity research includes biomarker research, and has further addressed immuno-regulatory effects in asthma, COPD, obesity and atherosclerosis. The matrix research comprises basic biochemical molecular characterization of specific matrix component and studies of gene deficient mice, including disease-models of neointima formation, aneurysm formation, hypertension, ageing, asthma and airway enlargement. Innovative research has led to the development of an IP-protected matrix-blocking antibody, with efficacy in reduction of organ fibrosis and vascular leakage in retinal disease.
Methods and techniques
Click here to read about our methods
Collaborations within SDU
Professor Boye Lagerbon Jensen, IMM
Professor Uffe Holmskov
Associated professorJonas Heilskov Graversen, IMM
Associated professor Maria Bloksgaard, IMM
Associated professor Kirsten Madsen, IMM
Associated professor Kim Ravnskjær, BMB
and several OUH collaborations
Support received from
Augustinusfonden
The Danish Innovation Foundation
Novo Nordisk endocrinology and metabolism grant
Bioinnovaton Institute PoC
Novo Nordisk Bioscience and Basic Biomedicine
The Danish Research Council grant
Novo Nordisk Pre-Seed grant
The Lundbeck Foundation.
Information for students
Students at all levels are welcome to take contact for an informal discussion of possibilities for execution of a study. We are an ambitious group and our main focus at present is drug development. Accordingly, a main objective is currently to characterize and test the therapeutic capacity of our inhouse developeds drugs in various models in vitro and in vivo. We can offer studies at all levels (bachelor, ITEK, master, pregraduate, PhD). We expect you to be dedicated and work full time (including courses). The studies we can offer will change over time.
Example of short study (bachelor/ITEK): Expression and test of therapeutic inhibitor in cell culture proliferation
Example of master/pregraduate study: Interventional trial in mouse disease model
Example of PhD-study: Animal study with test of intervention in mouse disease model, and exploration of mechanism in cell cultures, combined with target analysis of human tissue samples.
Members of the research group
Associate Professor Anders Schlosser, aschlosser@health.sdu.dk
Technician Tine Rasmussen, tiner@health.sdu.dk
Post doc Seyda Ünsal, sunsal@health.sdu.dk
Associate professor Jesper Bonnet Moeller, IMM
Assistant Professor Bartosz Pilecki, bpilecki@health.sdu.dk
Lab technician Vicki Nielsen, vnielsen@health.sdu.dk
Phd- and additional students
Courses
Immunology: Medical study module 10
Respiratory fysiology: Medical and Biomedical studies module 5, Biomedical study SU502, Farmaci SU518, Audiologopedia, Health informatics and technology.
Course coordinator: Medical and Biomedical Module 3 (biochemistry, molecular and protein biology, enzyme kinetics, cancer biology, pharmacology)
Collaborations
https://portal.findresearcher.sdu.dk/da/persons/glsorensen