The heritability of BMI varies across the range of BMI-a heritability curve analysis in a twin cohort.
Int J Obes (Lond). 2022. Pubmed abstract[Epub ahead of print]
Heritability of retinal drusen in the Copenhagen Twin Cohort Eye Study.
Belmouhand M, Rothenbuehler SP, Hjelmborg JB, Dabbah S, Bjerager J, Sander BA, Dalgård C, Larsen M.
Acta Ophthalmol. 2022. Pubmed abstract [Epub ahead of print]
Cancer-related reductions in survival: extent and duration evaluated using a large cohort study of twins, 1943-2011.
Villumsen MD, Ahrenfeldt LJ, Christensen K, Ewertz M, Hjelmborg JB.
Cancer Epidemiol Biomarkers Prev. 2022. Pubmed abstract [Epub ahead of print]
Cancer in twin pairs discordant for smoking: The Nordic Twin Study of Cancer.
Korhonen T, Hjelmborg J, Harris JR, Clemmensen S, Adami HO, Kaprio J; Nordic Twin Study of Cancer (NorTwinCan) collaboration.
Int J Cancer. 2022 Jul 1;151(1):33-43. Pubmed abstract
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss.
Trpchevska N, Freidin MB, Broer L, Oosterloo BC, Yao S, Zhou Y, Vona B, Bishop C, Bizaki-Vallaskangas A, Canlon B, Castellana F, Chasman DI, Cherny S, Christensen K, Concas MP, Correa A, Elkon R; Estonian Biobank Research Team, Mengel-From J, Gao Y, Giersch ABS, Girotto G, Gudjonsson A, Gudnason V, Heard-Costa NL, Hertzano R, Hjelmborg JVB, Hjerling-Leffler J, Hoffman HJ, Kaprio J, Kettunen J, Krebs K, Kähler AK, Lallemend F, Launer LJ, Lee IM, Leonard H, Li CM, Lowenheim H, Magnusson PKE, van Meurs J, Milani L, Morton CC, Mäkitie A, Nalls MA, Nardone GG, Nygaard M, Palviainen T, Pratt S, Quaranta N, Rämö J, Saarentaus E, Sardone R, Satizabal CL, Schweinfurth JM, Seshadri S, Shiroma E, Shulman E, Simonsick E, Spankovich C, Tropitzsch A, Lauschke VM, Sullivan PF, Goedegebure A, Cederroth CR, Williams FMK, Nagtegaal AP.
Am J Hum Genet. 2022 Jun 2;109(6):1077-1091. Pubmed abstract
Multivariate Generalized Linear Models for Twin and Family Data.
Bonat WH, Hjelmborg JVB.
Behav Genet. 2022 Mar;52(2):123-140. PMID: xxx
Familial risk and heritability of ischemic heart disease and stroke in Danish twins.
Osler M, Villumsen MD, Jørgensen MB, Hjelmborg JVB, Christensen K, Wium-Andersen MK.
Scand J Public Health. 2022 Mar;50(2):199-204. PMID: 32880216
Evidence of gene-gene interaction in hidradenitis suppurativa: a nationwide registry study of Danish twins.
Kjaersgaard Andersen R, Clemmensen SB, Larsen LA, Hjelmborg JVB, Ødum N, Jemec GBE, Christensen K.
Br J Dermatol. 2022 Jan;186(1):78-85. PMID: 34289077
2020
Apolipoprotein E ε4 and cognitive function after surgery in middle-aged and elderly Danish twins.
Dokkedal U, Wod M, Thinggaard M, Hansen TG, Rasmussen LS, Christensen K, Mengel-From J.
Eur J Anaesthesiol. 2020 Nov;37(11):984-991. Pubmed abstract
Monozygotic twin differences in perceived age.
Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors.
I:
Thinggaard, M. & Christensen, K.Matias, A. & Blickstein, I. (red.).
Academic Press, 2020;s. 306-318.
Heritability of subfertility among Danish twins.
Fertil Steril. 2020 Sep;114(3):618-627. Pubmed abstract
Gene-Environment Interplay Between Physical Exercise and Fitness and Depression Symptomatology.
J
Behav Genet. 2020 Sep;50(5):346-362. Pubmed abstract
Migraine with aura in women is not associated with structural thalamic abnormalities.
Neuroimage Clin. 2020 Jul;28:102361. Pubmed abstract
A decade of epigenetic change in aging twins: Genetic and environmental contributions to longitudinal DNA methylation.
Aging Cell. 2020 Jul;19(8):e13197. Pubmed abstract
The twin representativeness assumption.
Neurosci Biobehav Rev. 2020 May;112:374-375. Pubmed abstract
A genome-wide integrative association study of DNA methylation and gene expression data and later life cognitive functioning in monozygotic twins.
Soerensen M, Hozakowska-Roszkowska DM, Nygaard M, Larsen MJ, Schwämmle V, Christensen K, Christiansen L, Tan Q.
Front Neurosci. 2020 Apr;14:233. Pubmed abstract
Heritability of Curve Patterns in Oral Glucose Tolerance Test.
Twin Res Hum Genet. 2020 Feb;23(1):39-44. Pubmed abstract
Opposite-sex and same-sex twin studies of physiological, cognitive and behavioral traits.
Ahrenfeldt LJ, Christensen K, Segal NL, Hur YM.
Neurosci Biobehav Rev. 2020 Jan;108:322-340. Pubmed abstract
Longitudinal Twin Study of Subjective Health: Differences in Genetic and Environmental Components of Variance Across Age and Sex.
Finkel D, Franz CE, Christensen K, Reynolds CA, Pedersen NL.
J Gerontol B Psychol Sci Soc Sci. 2020 Jan 1;75(1):1-10. PubMed abstract
Clonal hematopoiesis in elderly twins: concordance, discordance and mortality.
Hansen JB, Pedersen DA, Larsen LA, Husby S, Clemmensen SB, Hjelmborg J, Favero F, Weischenfeldt J, Christensen K, Grønbæk K.
Blood J. 2020 Jan;135 (4): 261–268. Pubmed abstract
Sources of Stability in Social and Economic Ideological Orientations: Cohort, Context, and Construct Effects.
Ksiazkiewicz A, Klemmensen R, McGue M, Christensen K, Dawes C, Nørgaard AS.
Int J Pub Op Res. 2020 Jan.
Harnessing the power of twins in epigenetic association studies: causal inference and more.
Tan Q.
Epigenomics. 2020 Jan;12(1):1-3. PubMed
2019
The Nordic Twin Study on Cancer - NorTwinCan.
Harris JR, Hjelmborg J, Adami HO, Czene K, Mucci L, Kaprio J; Nordic Twin Study of Cancer (NorTwinCan) Collaboration.
Twin Res Hum Genet. 2019 Dec;22(6):817-823. Pubmed abstract
DNA methylome profiling in identical twin pairs discordant for body mass index.
Li W, Zhang D, Wang W, Wu Y, Mohammadnejad A, Lund J, Baumbach J, Christiansen L, Tan Q.
Int J Obes (Lond). 2019 Dec;43(12):2491-2499. Pubmed abstract
IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies - An Update.
Pedersen NL, Gatz M, Finch BK, Finkel D, Butler DA, Dahl Aslan A, Franz CE, Kaprio J, Lapham S, McGue M, Mosing MA, Neiderhiser J, Nygaard M, Panizzon M, Prescott CA, Reynolds CA, Sachdev P, Whitfield KE.
Twin Res Hum Genet. 2019 Dec;22(6):809-816. Pubmed abstract
Advanced Parental Age at Conception and Sex Affects Mitochondrial DNA Copy Number in Human and Fruit Flies.
Mengel-From J, Svane AM, Pertoldi C, Nygaard Kristensen T, Loeschcke V, Skytthe A, Christensen K, Lindahl-Jacobsen R, Hjelmborg J, Christiansen L.
J Gerontol A Biol Sci Med Sci. 2019 Nov;74(12):1853-1860. Pubmed abstract
Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
Soerensen M, Li W, Debrabant B, Nygaard M, Mengel-From J, Frost M, Christensen K, Christiansen L, Tan Q.
Biogerontology. 2019 Oct;20(5):627-647. Pubmed abstract
Epigenome-wide association study of depression symptomatology in elderly monozygotic twins.
Starnawska A, Tan Q, Soerensen M, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.
Transl Psychiatry. 2019 Sep;9(1):214. Pubmed abstract
The association between depressive mood and ischemic heart disease: a twin study.
Wium-Andersen MK, Wium-Andersen IK, Jørgensen MB, McGue M, Jørgensen TSH, Christensen K, Osler M.
Acta Psychiatr Scand. 2019 Sep;140(3):265-274. Pubmed abstract
The risk of asthma is increased among women with polycystic ovary syndrome: a twin study.
Zierau L, Meteran H, Backer V, Lindenberg S, Skytthe A, Thomsen SF.
ERJ Open Res. 2019 Sep;5(3). Pubmed abstract
Epigenome-wide association study of leukocyte telomere length.
Lee Y, Sun D, Ori APS, Lu AT, Seeboth A, Harris SE, Deary IJ, Marioni RE, Soerensen M, Mengel-From J, Hjelmborg J, Christensen K, Wilson JG, Levy D, Reiner AP, Chen W, Li S, Harris JR, Magnus P, Aviv A, Jugessur A, Horvath S.
Aging (Albany NY). 2019 Aug;11(16):5876-5894. Pubmed abstract
Global expression profiling of cognitive level and decline in middle-aged monozygotic twins.
Nygaard M, Larsen MJ, Thomassen M, McGue M, Christensen K, Tan Q, Christiansen L.
Neurobiol Aging. 2019 Aug;84:141-147. Pubmed abstract
The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins.
Silventoinen K, Hjelmborg JVB, Christensen K, Skytthe A, Kyvik KO, Tan Q, McGue M, Kaprio J. et al
Twin Res Hum Genet. 2019 Jul 31:1-9. Pubmed abstract
Tupakoinnin vaikutus geneettiseen keuhkosyöpäalttiuteen - tutkimuksen tuloksia Nordic Twin Study of Cancer (NorTwinCan)
Kaprio J, Brandt I, Harris J R, Hjelmborg JB.
BestPractice Nordic. 2019 Apr.
Enriched power of disease-concordant twin-case-only design in detecting interactions in genome-wide association studies.
Li W, Baumbach J, Mohammadnejad A, Brasch-Andersen C, Vandin F, Korbel JO, Tan Q.
Eur J Hum Genet. 2019 Apr;27(4):631-636. Pubmed abstract
Is aberrant affective cognition an endophenotype for affective disorders? - A monozygotic twin study.
Meluken I, Ottesen NM, Harmer CJ, Scheike T, Kessing LV, Vinberg M, Miskowiak KW.
Psychol Med. 2019 Apr;49(6):987-996. Pubmed abstract
Is who you ask important? Concordance between survey and registry data on medication use among self- and proxy-respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study.
Oksuzyan A, Sauer T, Gampe J, Höhn A, Wod M, Christensen K, Wastesson JW.
J Gerontol A Biol Sci Med Sci. 2019 Apr;74(5):742-747. Pubmed abstract
Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.
Skytthe A, Harris JR, Czene K, Mucci L, Adami HO, Christensen K, Hjelmborg J, Holm NV, Nilsen TS, Kaprio J, Pukkala E.
Twin Res Hum Genet. 2019 Apr;22(2):99-107. Pubmed abstract
Lifespans of Twins: Does Zygosity Matter?
Hjelmborg J, Larsen P, Kaprio J, McGue M, Scheike T, Hougaard P, Christensen K.
Genes (Basel). 2019 Feb 20;10(2). Pubmed abstract
Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts.
Jylhävä J, Hjelmborg J, Soerensen M, Munoz E, Tan Q, Kuja-Halkola R, Mengel-From J, Christensen K, Christiansen L, Hägg S, Pedersen NL, Reynolds CA.
EBioMedicine. 2019 Feb;40:710-716. Pubmed abstract
Hvordan røyking påvirker den genetiske disposisjonen for lungekreft - resultater fra Nordic Twin Study of Cancer (NorTwinCan)
Kaprio J, Brandt I, Harris J R, Hjelmborg JB.
BestPractice Nordic: Onkologia/Hematologia. 2019 Feb.
A major limitation of the direction of causation model: non-shared environmental confounding.
Rasmussen SHR, Ludeke S, Hjelmborg JVB.
Twin Res Hum Genet. 2019 Feb;22(1):14-26. Pubmed abstract
White blood cell mitochondrial DNA copy number is decreased in rheumatoid arthritis and linked with risk factors. A twin study.
Svendsen AJ, Tan Q, Jakobsen MA, Thyagarajan B, Nygaard M, Christiansen L, Mengel-From J.
J Autoimmun. 2019 Jan;96:142-146. Pubmed abstract