Available infrastructure
| Manufacturer | Model | Description | Features/Comments |
| University of Southern Denmark (SDU) | |||
| Thermo | Orbitrap Astral (x2) | LC-MS systems for quantitative proteomics | One Astral system with Pharma option (high mass) |
| Bruker | timsTOF Ultra 2 | Hybrid QTOF/ion mobility spectrometer | PASEF |
| Bruker | NeofleX | MALDI TOF MS/MS system | Bioimaging software |
| Aarhus University (AU) | |||
| Bruker | timsTOF fleX MALDI-2 | MALDI-MS imaging of biological surfaces and tissue sections | Chemical imaging capabilites with 10 micron spatial resolution and post laser ionization |
| Aalborg University (AaU) | |||
| SCIEX | 8600 | LC-MS EvosepENO-8600 for immunoproteomics | EAD sequencing |
| MMI LCM | Zeiss Cellcut/Cellscan | ||
| University of Copenhagen (KU) | |||
| Waters | Xevo TQ Absolute with DESI XS | Triple-quadrupole system for targeted DESI-MSI and LC-MS | Ultra-sensitive chemical imaging with 20 µm spatial resolution |
| Technical University of Denmark (DTU) | |||
| Thermo | Orbitrap Exploris 480 | LC-MS system for quantitative proteomics | |
| Leica | LMD6 | LCM for spatial dissection of slides | |
| Odense University Hospital (OUH) | |||
| Thermo | Orbitrap Astral | MS system for quantitative clinical proteomics | Standard version |
Services for users/collaborators will include:
- Consultancy during project design and experimental strategy
- Instruction in sample preparation and protocols
- Instruction in sample analysis by mass spectrometry (for visiting scientists)
- Iinstruction and supervision in data analysis and statistical analysis (for visiting scientists)
- Access to results and datafiles on cloud service or secure servers
- Follow-up meetings and discussions on data interpretation
- Assistance in preparation of manuscripts and figures for publications and presentations
- Deposition of data in public repositories on internet (PRIDE, ProteomeXchange)
Access
For access to PLATO research infrastructure, contact the PLATO director or a representative of a partner institution with a short, written outline of a project proposal, including aims, proposed methods, time plan, resource needs (personnel, reagents), expected results and suggestions for follow-up experiments.
The partner site representative will ensure that there is a single-point-of-contact at the PLATO partner site. The interested party will name a contact person for project planning and execution. This will often be a postdoc or PhD student who will be involved in the project as a guest/visiting researcher at the PLATO partner site.
Project execution will be planned for an available time period. Costs for mass spectrometry experiments are covered by PLATO (instrument time, maintenance, staff), whereas users will cover extraordinary expenses for sample preparation, i.e. enzymes, special reagents, chromatography columns and consumables.
