Our research focuses on the development and applications of mass spectrometry-based lipidomics and proteomics technologies for systems biology studies of lipid metabolism and its regulation in health and disease. We use state-of-the-art mass spectrometry technology, deploy integrated proteomics and lipidomics workflows and execute functional studies to characterize the molecular underpinning of lipid homeostasis in a variety of model organisms.
Selected publications (for full list see here: PubMed):
Lipid molecular timeline profiling reveals diurnal crosstalk between the liver and circulation.
Sprenger et al.,
Cell Rep. 2021 34(5):108710.
Phosphoproteomic Analysis across the Yeast Life Cycle Reveals Control of Fatty Acyl Chain Length by Phosphorylation of the Fatty Acid Synthase Complex.
Martínez-Montañés et al.,
Cell Rep. 2020 32(6):108024.
MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes.
Freyre et al.,
Mol Cell. 2019 76(5):811-825.
Automated, parallel mass spectrometry imaging and structural identification of lipids.
Ellis et al.,
Nat Methods. 2018 15(7):515-518.
Head of research: Associate professor, PhD Christer Ejsing
Group webpages: www.msLipidomics.info
A complete list of publications by Christer Ejsing can be found here.
Part of the Research sections of Biomedical Mass Spectrometry at the Department of Biochemistry and Molecular Biology