Skip to main content

Growing old but not growing apart...

Twin similarity in the latter half of the lifespan. An investigation of age moderation regarding twin similarity in cognitive ability, depression symptomatology and hand grip strength in 2,332 Danish twin pairs aged 46-96 years.

While a substantial amount of behavioral genetic research has helped to characterize developmental trends in twin similarity in early life, relatively little is known about changes in twin similarity with age in adulthood. We investigated age moderation of twin similarity for a composite measure of cognitive ability, depression symptomatology and hand grip strength in a cross-sectional sample of 2,332 like-sex pairs of Danish twins age 46-96 years.

All three outcomes were strongly correlated with age, indicating that the three phenotypes analyzed are not developmentally static. Nonetheless, in moderated regression analysis we found no evidence of declining twin similarity for any of the three outcomes in either zygosity group.

March_2013

Moreover, biometric analysis of the twin data revealed minimal differences in heritability estimates across the age range sampled. While small sample size limits our ability to draw firm conclusions at very advanced ages, these findings call into question the hypothesis that the cumulative impact of life experiences diminishes twin similarity at least through age 80.

We hypothesize that twins are able to maintain similarity over extended periods of time because in part they are able to construct similar environments that reinforce that similarity.

Original title:
Growing old but not growing apart: the similarity in the latter half of the lifespan.
Matt McGue & Kaare Christensen.
In: Behavior Genetics 2013 Jan; 43(1):1-12. Pubmed abstract