Associate Professor Rasmus Siersbæk has headed a research group at SDU since 2019. He received his PhD from SDU in 2012 and stayed on as a postdoc at SDU until 2015. He then moved to Cambridge (UK) to do a 4-year postdoc in the laboratory of Dr. Jason Carroll at the Cancer Research UK Cambridge Institute, University of Cambridge. He started his independent research group at SDU as an assistant professor in 2019 and was promoted to associate professor in 2022.
Research in Rasmus’ group focuses on the transcriptional and epigenetic mechanisms controlling cell function in the context of breast cancer. Transcription factors and their associated co-regulatory proteins function as key determinants of the cellular phenotype by specifying the active gene programmes in the cell. Rasmus’ group uses an integrated omics-approach involving both genomics and proteomics technologies to investigate the mechanisms through which these proteins work together to define cell function. The lab is particularly interested in the transcriptional and epigenetic mechanisms controlling progression and treatment responses in breast cancer, the most common cancer type affecting women. This includes a strong interest in tumourigenic pathways controlled by non-malignant cells in the tumour microenvironment. The goal of the lab to identify new therapeutic avenues for the treatment of breast cancer through an in-depth understanding of the basic mechanisms controlling this disease.
Head of research: Associate professor, PhD Rasmus Siersbæk
Researchers and research group: Rasmus Siersbæk Lab
Group webpage: Rasmus Siersbæk group
A complete list of publications by Rasmus Siersbæk can be found here.
Part of the Research section Functional Genomics at the Department of Biochemistry and Molecular Biology