Head of Research Group
Jesper Bonnet Moeller
Associate Professor, PhD.
Inflammation Research Unit
Department of Molecular Medicine
University of Southern Denmark
Campusvej 55
5230 Odense M
+45 2231 7390
jbmoeller@health.sdu.dk
https://www.sdu.dk/ansat/jbmoeller
Summary of Research interests
Over the years, our research has primarily focused on understanding host-microbe interactions at the barrier surfaces, from characterizing specific molecular mechanisms to investigating the many consequences these interactions have on human health and disease.
After my Ph.D. I had the opportunity to do a four-year postdoc at Weill Cornell Medicine, New York – USA, under the mentoring of Professor David Artis. In the Artis lab, I employed diverse models of pathogen infection and chronic inflammation to examine how mammalian host genetics and signals derived from the microbial communities influence innate and adaptive immunity in the skin, lungs, and intestines. These results led to several co-authorships in high-impact Journals, including Nature and Science, and a first authorship in the Journal of Experimental Medicine.
After returning to the University of Southern Denmark, I have established a research group that builds upon my experiences, skills, and professional network acquired at Weill Cornell Medicine. Furthermore, to support and develop my own research program, I have co-founded the Center for Advanced Cell Analysis, a core facility providing best-in-class high-parameter flow cytometry and cell sorting to the research communities at the University of Southern Denmark.
Utilizing these powerful tools combined with other state-of-the-art technologies, research in the Moeller lab currently focuses on understanding how eukaryotic commensal microorganisms such as fungi and protozoa influence health and disease. In close collaboration with local experts and colleagues abroad, my students, co-workers, and lab technician in the Moeller lab employ novel animal models of colonization combined with models of human diseases to investigate how these commensal microbial communities directly interact with the host and, through these interactions, influence the complex mechanisms that control tissue homeostasis and disease development at the barrier surfaces.
Key Methods & Methodologies
Click here to read about our methods
Collaborations within SDU
Professor Grith L. Sorensen (main collaborator) – Inflammation Unit, IMM
Professor Vibeke Andersen - Inflammation Unit, IMM
Professor Daniel Ketelhuth - Cardiovascular and Renal Research, IMM
Professor Per Svenningsen - Cardiovascular and Renal Research, IMM
Professor Kate L. Lambertsen – Neurobiology Unit, IMM
Associate Professor Mikkel G. Terp – Cancer Unit, IMM
Associate Professor Kim Ravnskjaer – Dept. of Biochemistry and Molecular Biology
Associate Professor Jonas Graversen - Inflammation Unit, IMM
Professor Steffen Husby – Dept. of Clinical Research
Professor Mark Ellebaek - Dept. of Clinical Research
Clinical Centre of Excellence (GAIN) – OUH
The H.C. Andersen Children’s Hospital – OUH
The Department of Surgery – OUH
Support received from
The Novo Nordisk Foundation (several)
Dagmar Marshalls Fond
Fabrikant Einar Willumsens Mindelegat
Beckett Fonden
Louis-Hansen Fonden
Current Members of the Research Group
Technician Rikke Hadow, hadow@health.sdu.dk
Postdoc Magdalena Dubik, mdubik@health.sdu.dk
Postdoc Kamilla Hegn,
PhD-student Kat Kiilerich, kakiilerich@health.sdu.dk
PhD-student Rasmus M. Duus, rduus@health.sdu.dk
Courses
PhD course: Introduction to Flow Cytometry and Cell Sorting
Immunology: Medical study module 10
Immunology: BMB512 theoretical immunology
Course director: for the Flow Cytometry PhD Course