Infectious diseases

The research of infectious diseases at the Department of Clinical Immunology is centered around the laboratory of HIV and Hepatitis infections. The laboratory has a very broad range of analyses of disease markers of HIV and hepatitis to support the diagnostic process. We collaborate with laboratories at the other Departments of Clinical Immunology in Denmark as well as a number of clinical groups, amongst them Professor Peer Brehm Christensens group at the Department of Infectious diseases, OUH. The research projects are mainly focused on the prevalence of hepatitis or other infectious diseases among different patient groups as well as blood donors in Denmark as well as optimization of currents methods.

Members of the team

Dorte Kinggaard Holm, MSc PhD
Minna Christiansen Lund, MSc, Ph.D.
Collaborators from clinical departments

 

Ongoing projects

Monitoring re-infection and re-treatment after successfull Hepatitis C treatment in people with injecting drug use in opioid agonist therapy.

Hepatitis C among persons connected to Drug Treatment Centers - Test and treatment outcome

 

Project options for students
 Students are welcome to contact the team for inquirires about projects.

 

Selected publications

Hepatitis C screening and linkage to care with a mobile clinic in Southern Denmark. Dröse S, Øvrehus ALH, Holm DK, Røge BT, Christensen PB. Int J Drug Policy. 2023 Nov;121:104180. 

Four Weeks Treatment with Glecaprevir/Pibrentasvir + Ribavirin-A Randomized Controlled Clinical Trial.  Madsen LW, Christensen PB, Hansen JF, Røge BT, Holm DK, Dröse S, Øvrehus A.Viruses. 2022 Mar 16;14(3):614.

A multi-level intervention to eliminate hepatitis C from the Region of Southern Denmark: the C-Free-South project.  Dröse S, Øvrehus ALH, Holm DK, Madsen LW, Mössner BK, Søholm J, Hansen JF, Røge BT, Christensen PB.BMC Infect Dis. 2022 Mar 1;22(1):202.

Epidemiology of hepatitis E virus infection in a cohort of 4023 immunocompromised patients. Harritshøj LH, Hother CE, Sengeløv H, Daugaard G, Sørensen SS, Jacobsen S, Perch M, Holm DK, Sækmose SG, Aagaard B, Erikstrup C, Hogema BM, Lundgren JD, Ullum H.Int J Infect Dis. 2020 Feb;91:188-195.

 Incidence, prevalence and risk factors for hepatitis C in Danish prisons.  Søholm J, Holm DK, Mössner B, Madsen LW, Hansen JF, Weis N, Sauer AP, Awad T, Christensen PB.PLoS One. 2019 Jul 26;14(7):e0220297. 

Vertical transmission of hepatitis B virus during pregnancy and delivery in Denmark.  Weis N, Cowan S, Hallager S, Dröse S, Kristensen LH, Grønbæk K, Jensen J, Gerstoft J, Madsen LG, Clausen MR, Lunding S, Tarp BD, Barfod TS, Sloth S, Holm DK, Jensen J, Krarup H.Scand J Gastroenterol. 2017 Feb;52(2):178-184.

Declining prevalence of hepatitis E antibodies among Danish blood donors.  Holm DK, Moessner BK, Engle RE, Zaaijer HL, Georgsen J, Purcell RH, Christensen PB. Transfusion. 2015 Jul;55(7):1662-7.