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Applied Clinical Biochemistry

 

Contact person

Mads Nybo,  E- mail:  mads.nybo@rsyd.dk
Associate Professor, MD, PhD, Chief Physician, Department of Clinical Biochemistry,  https://portal.findresearcher.sdu.dk/en/persons/mnybo

 

Research aim

Our aim is to disclose relevant aspects in the preanalytical, analytical and postanalytical phase related to standard/routine biomarkers performed at established platforms. Also, to support and use data extraction for reference intervals, demand management projects and studies of a more epidemiological nature.

 

Project examples

  • Sixteen years of creatinine measurements among 460 000 individuals-The Funen Laboratory Cohort (FLaC), a population-based pharmaco-epidemiological resource to study drug-induced kidney disease
  • Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome (PCOS)
  • Hemolysis as a potential biomarker of occult disease

 

Available cohorts and infrastructures

The Funen Laboratory Cohort (FLaC)

Collaborators

  • Daniel P. Henriksen, Department of Clinical Pharmacology, OUH
  • Janne Cadamuro, Uniklinikum Salzburg, Austria
  • The Nordic Preanalytical Scientific Working Group (under NFKK)

Publication examples

  • Hansen RS, Revsholm J, Henriksen DP, Lund LC, Nybo M. Diagnoses and mortality in a population without acute myocardial infarction, but with elevated high-sensitive troponin I - a retrospective register-based single center study. Acute Med 2021;20:18-24
  • Gils C, Sandberg MB, Nybo M. Verification of the hemolysis index measurement: imprecision, accuracy, measuring range, reference interval and impact of implementing analytically and clinically derived sample rejection criteria. Scand J Clin Lab Invest 2020;80:580-9
  • Kristensen MS, Green A, Nybo M, Hede SM, Mikkelsen KH, Gislason G, Larsen ML, Ersbøll AK. Lipid-lowering therapy and low-density lipoprotein cholesterol goal attainment after acute coronary syndrome: a Danish population-based cohort study. BMC Cardiovasc Disord 2020;20:336.

Last Updated 20.10.2023