In the medicinal chemical field, we work with both small and large molecules. The small molecules are expected to be used in the fight against, for example, infectious diseases caused by bacteria or viruses, cancer or perhaps diabetes. The molecules are produced in organic synthesis and are examined during the process with spectroscopy.
The large molecules are typically based on modifications of DNA, proteins or fats. The strategy here is to create systems that improve the uptake of drugs or using synthetic DNA as a new way to combat, among others, genetic diseases, cancer or viruses.
Medicinal Chemistry is fundamentally interdisciplinary. Computer calculations are an important element in the design of the new molecules. Organic chemistry is the fundamental element in the production of the new substances. The new substances are tested in both simple assays for their binding to target molecules such as enzymes or receptors, but they are also tested on biological systems such as bacteria or cells. Medicinal Chemistry therefore requires close cooperation with experts within computer chemistry, molecular biology, pharmacy and medicine.