LLFS : Long Life - FamilyStudy
Longitudinal study of families from the U.S. and Denmark with multiple members who have reached an very old age. Siblings are enrolled together with their children, cousins and spouses.
| 2008-2024 | Project description |
Genetics and Epigenetics - Aging and Longevity
Study on the association between variation in the genome, epigenome and transcriptome associated with longevity and age-related traits. We use DNA from middle-aged and older twins, combined with survey data regarding a variety of traits related to health and functional capacity.
| 2019-2022 | Project description |
IGEMS: Interplay of Genes and Environments
The IGEMS consortium is a collaboration involving fifteen longitudinal twin studies of adult development and aging. The aims are to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.
| 2014-2020 | Project description |
Epigenetic signatures of early-life events
PhD project: The proposed project is the first large epigenomic study focusing on early life events and later life health. The project will be based on an existing collaboration network of Danish and Chinese scientists with expertise in studying complex diseases, genetic epidemiology, bioinformatics and public health.
| 2016-2019 | Project description |
Epigenetic biomarkers as predictors of late-life mortality in the elderly
PhD Project: Taking advantage of the genomic data, we aim at developing highly efficient models for predicting late-life mortality in the elderly by identifying prognostic epigenetic biomarkers using bioinformatics and statistics tools.
| 2016-2020 | Project description |
Pleiotropic genetic effects on cognitive performance
PhD Project: The aim is to introduce and perform the first multivariate GWAS on cognitive performances in old age twins, in search of genetic variants that are pleiotropic for different domains of cognition and domain-specific genetic variants.
| 2018-2021 | Project description |