Carcinogenesis is driven by a crumbling of the cellular genomic architecture. The changes in the DNA of cancer cells ranges from single mutations to swapping of entire chromosome arms. This makes cancer an exceedingly complex disease to handle as each single case is unique.
Understanding how DNA damage is inflicted and finding common patterns in the genomic transformations of tumorigenic cells can bring us closer to nature of cancer emanate and develops.
Member of the steering committee
Vijay Tiwari
Uses genomics and compu-tational biology to decode cancer metastasis and chemoresistance
Member of the steering committee
Mads Thomassen
Investigates the molecular mechanisms and genomic wiring of a wide range of cancers