Type: Cell culture · Wet lab · Limited proteomics (optional)
Project description
This project focuses on understanding how human hepatocytes mature in vitro and which factors promote adult-like liver function. A central question is the role of extracellular matrix accumulation and non-parenchymal cells during maturation.
Example project aim
To investigate how extracellular matrix composition and the presence of non-parenchymal cells influence maturation of iPSC-derived hepatocytes.
Project description
This project focuses on understanding how human hepatocytes mature in vitro and which factors promote adult-like liver function. A central question is the role of extracellular matrix accumulation and non-parenchymal cells during maturation.
Example project aim
To investigate how extracellular matrix composition and the presence of non-parenchymal cells influence maturation of iPSC-derived hepatocytes.