Review from ATLAS and FLASH researchers on the newest methods to examine severely obese patients for liver disease
It is important gain a better understanding of which patients develops progressive liver fibrosis from fatty liver disease, and why. We therefore set out to describe the newest methods to investigate liver damage in patients with severe obesity.
Obesity increases the risk of fatty liver disease, but current scanning methods and blood-based tests are imprecise, and difficult to apply on severely obese patients with very large abdominal circumference and subcutaneous fat. The review first describes the diagnostic methods used today in hospitals and among general practitioners, to highlight their pro’s and con’s. We show that even the best diagnostic tests used today often fails when it comes to predicting which patients with fatty liver will develop fibrosis (scarring) of the liver. The second part of the review therefore gazes into the crystal ball, and goover how new promising methods in genomics, metabolomics, and especially single cell sequencing may be key to improved diagnostic tests and a deepened understanding of pathophysiology.
The review is online with Open Access. LINK to the article.
Four researchers from ATLAS and FLASH are behind the the publication. To read more about the ATLAS project follow this LINK to the ATLAS website.
The review is online with Open Access. LINK to the article.
Four researchers from ATLAS and FLASH are behind the the publication. To read more about the ATLAS project follow this LINK to the ATLAS website.