Plasticity of white adipose tissue at single-nucleus resolution in response to diet-induced obesity in mice
Using single-nucleus RNA-seq, the Mandrup Group shows in a collaborative study with the Madsen Group that diet-induced obesity in male mice leads to major transcriptional changes in all cell types in epididymal adipose tissue. They show that in vivo adipocyte differentiation is affected by obesity and demonstrate the existence of three adipocyte subpopulations, one of which is lost in obesity.
ATLAS annual meeting 2020 went hybrid, and it was a success
Plenty of distance, a combination of online and on-site activities, and enthusiastic center members made this year’s annual meeting possible and successful.
Towards a fast corona test
ATLAS researcher collaborates with Danish biotech company to develop antibodies for a home test for COVID-19. When ready, in just 10 min. the test can tell whether you have COVID-19 virus particles in your body, even before you experience any symptoms. The applications are enormous.
New publication in Nature Genetics shows that 3D enhancer communities play an important role in stem cell differentiation
A new study published by the Mandrup group reveals wide-spread interactions between transcriptional enhancers involved in driving stem cell differentiation.
Five young researchers join ATLAS this Fall
This Fall we onboard five dedicated young PhD fellows and Postdocs who over the coming years will contribute to our work towards understanding fat and liver tissue plasticity.
New publication in PLOS Genetics on molecular mechanisms controlling thyroid hormone receptor activity in the liver
The Grøntved group has just published a study revealing different mechanisms behind thyroid hormone receptor-mediated gene regulation in the liver
ATLAS has recruited new Assistant Professor in Computational Biology
ATLAS is pleased to announce that Jesper Grud Skat Madsen, has been appointed as Assistant Professor in Computational Biology
Human Cell Atlas: Mapping the human body once cell at a time – a virtual lecture by Dr. Sarah Teichmann
Dr. Sarah Teichmann, Group Leader at Sanger Institute and co-PI of the Human Cell Atlas will discuss how this ambitious global initiative provides unprecedented understanding of human cells and tissues in health and diseases such as cancer and Covid-19 infection.
Basic research in a Center of Excellence
New study in Hepatology
New technology to investigate the cellular processes as they change during fibrosis development
Molecular basis of human enhanceropathies - ENHPATHY
ENHPATHY is a multidisciplinary science consortium created in the frame of the Marie Sklodowska-Curie actions (MSCA)-ITN-ETN European Training Networks call and regrouping 15 academic and 9 non-academic European organisations in the continuum of basic, translational and clinical research on enhancers and associated diseases.
The Order of Dannebrog
Head of ATLAS, Professor Susanne Mandrup has been knighted with The Order of Dannebrog
Research Dissemination Prize 2019 to ATLAS researcher
The University of Southern Denmark´s Research Dissemination Prize is awarded to a researcher for the spirited, creative communication of his/her academic field aimed at a broad audience.
Does your liver have a memory?
Support to ATLAS PI, Associate Professor Kim Ravnskjaer and his group from Novo Nordisk
Grant to ATLAS Assistant Professor
ATLAS PI, Associate Professor, Lars Grøntved has received a new grant
Obesity - a major risk factor for development of a plethora of life-threatening metabolic diseases
A multidisciplinary symposium with international top scientists
Grant to our Project Student
ATLAS Project Student Trine Vestergaard Dam, receives a grant from Danish Diabetes Academy.
Official opening of Center for Adipocyte Signaling - ADIPOSIGN
On May 27, 2019 Center for Adipocyte Signaling (ADIPOSIGN) opens at the University of Southern Denmark (SDU)
And the prize goes to 2 ATLAS partners
Odd Fellow Order Prize 2019.
The Danish Science Festival - Forskningens Døgn
A great day with many curious kids.
To be or not to be a fat cell – a question of transcription factor network
A new publication is out in Nature Genetics entitled “Osteogenesis depends on commisioning of a network of stem cell transcription factors that act as repressors of adipogenesis"
New publication in Nature Scientific Reports on transcriptional regulation in Non-alcoholic steatohepatitis
New paper from the Ravnskjaer Group in Nature Scientific Reports describes their identification of ETS1 and RUNX1 as transcriptional drivers of "Western" diet-induced liver fibrosis in mouse models of human Non-alcoholic steatohepatitis (NASH).
ATLAS Director expands obesity research with a new center
ATLAS Director Susanne Mandrup receives DKK 60 million from the Novo Nordisk Foundation’s Challenge Program for the establishment of a new research center – ADIPOSIGN – Center for Adipocyte Signaling. Together with ATLAS, the new center clearly demonstrates how SDU is at the forefront when it comes to research within obesity, functional genomics and metabolism
A most precious biopsy
Follow ATLAS researchers when they take out tissue samples from a patient
Fifty shades of Brown - On Plasticity of Thermogenic Adipocytes
ATLAS researchers recently published a review article in BioZoom highlighting the heterogeneity and plasticity of brown and white adipocytes.
ATLAS Center Director co-organizes international meeting
Center Director Susanne Mandrup co-organizes the 4th Cold Spring Harbor Laboratories meeting on Mechanisms of Metabolic Signaling and Disease
ATLAS Annual Meeting 2018
The first ATLAS Annual Meeting was a huge success. Great scientific presentations and discussions, and constructive ideas for the coming years - no doubt we are on the right track with a strong team in ATLAS!
Professor Blagoy Blagoev receives funding for exciting proteomics project
ATLAS Professor Blagoy Blagoev receives DKK 2.592.000,- from the Independent Research Fund Denmark for the project “Unraveling the puzzle of ubiquitin and ubiquitin-like protein modifications”.
ATLAS Seminar Series has been launched
Tune H. Pers and Benedicte M. Pers initiate the ATLAS Seminar Series with exciting talks on their research within the field of obesity
Measuring tiny interactions between proteins with the Octet
The newly arrived Octet RED96e enables ATLAS researchers to investigate tiny interactions between proteins in a high-throughput manner
ATLAS recruits two talented postdocs
Anitta K. Sárvári and Fabio Avolio joins ATLAS as postdoctoral fellows
ATLAS scientist promoted to Associate Professor
ATLAS is pleased to announce the promotion of Lars Grøntved to Associate Professor in Functional Genomics
NovaSeq 6000 has arrived at SDU
New Center of Excellence ATLAS ready to strengthen the investigation of obesity at the cellular level with the arrival of a state-of-the-art sequencer, the NovaSeq 6000.
Louise Cathrine Braun Olsen Elmelund-Præstekær will be new Centeradministrator in ATLAS and PA to Susanne Mandrup from January 1, 2018
Sapere Aude - Starting Grant
Lars Grøntved, PI in ATLAS, Center for Functional Genomics and Tissue Plasticity, and Associate Professor in the Functional Genomics and Metabolism Research Unit, receives the prestigious Sapere Aude - Starting Grant.
Official Opening and Symposium
150 people joined us for the ATLAS opening and symposium
Start of ATLAS
The 1st of October 2017 was the official opening day of our new Center of Excellence, Center for Functional Genomics and Tissue Plasticity (ATLAS). We are very much looking forward to launch this center and work with the great colleagues in the center on our joint ambition to understand tissue plasticity at a molecular level.
Center Director Professor Susanne Mandrup elected as EMBO member