Together with the Functional Genomics & Metabolism Research Unit we host a distinguished seminar with two speakers. This will be an exciting opportunity to become updated on the intersections between metabolic disease, inflammation, and regeneration by world-leading scientists both of whom are engaging speakers.
14:15 - 15:05 Assoc. Prof. Tune Pers. Title: Mapping etiologic cell types for obesity using human genetics and single-cell data
15:10 - 16:00 Prof. Neil Henderson. Title: Using multi-modal single cell genomics to decode human liver disease
Assoc. Prof. Tune Pers is a leading expert in dissecting molecular pathways of the brain that regulate energy balance and mediate genetic susceptibility to metabolic disease. Recent important publications include:
A genetic map of the mouse dorsal vagal complex and its role in obesity. Ludwig et al. Nat Metab. 2021; 3(4):530-545.
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission. Bentsen et al. Nat Commun. 2020; 11(1).
Prof. Neil Henderson is Chair of Tissue Repair and Regeneration at the Centre for Inflammation Research and a pioneer in applying single-cell transcriptomics to understand wound healing, regeneration, and organ fibrosis. Recent landmark publications include:
Decoding myofibroblast origins in human kidney fibrosis. Kuppe et al. Nature. 2021; 589(7841):281-286.
Resolving the fibrotic niche of human liver cirrhosis at single-cell level. Ramachandran et al. Nature. 2019; 575(7783):512-518.