11. Beck, Kasper M.; Pham, Robert L.; Nanim, Rita A.; Laustsen, Anders; Nielsen, Poul. Double-headed nucleotides with increased base-pairing affinity and specificity. European Journal of Organic Chemistry, (2021), 2021, 6717-6724. [Abstract]
10. Umek, Tea; Olsson, Thomas; Gissberg, Olof; Saher, Osama; Zaghloul, Eman M.; Lundin, Karin E.; Wengel, Jesper; Hanse, Eric; Zetterberg, Henrik; Vizlin-Hodzic, Dzeneta; Smith, C. I. Edvard; Zain, Rula. Oligonucleotides targeting DNA repeats downregulate Huntingtin gene expression in Huntington’s patient-derived neural model system. Nucleic Acid Ther. (2021), 31, 443-456. [Open Access]
9. Georgiadou, Michaella; Christou, Melina; Sokratous, Kleitos; Wengel, Jesper; Michailidou, Kyriaki; Kyriacou, Kyriacos; Koutsoulidou, Andrie; Mastroyiannopoulos, Nikolaos P.; Phylactou, Leonidas A. Intramuscular evaluation of chimeric locked nucleic acid/2′Omethyl-modified antisense oligonucleotides for targeted exon 23 skipping in Mdx mice. Pharmaceuticals, (2021), 14, 1113. [Open Access]
8. Beck, Kasper M; Hornum, Mick; Risgaard, Nikolaj A; Nielsen, Poul; Sharma, Pawan K. Double-headed nucleic acids condense the molecular information of DNA to half the number of nucleotides. Chem. Commun. (2021), 57, 9128-9131. [Abstract]
7. Danielsen, Mathias B; Wengel, Jesper. Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides. Beilstein J. Org. Chem. (2021), 17, 1828-1848. [Abstract]
6. Laanesoo, Anet; Urgard, Egon; Periyasamy, Kapilraj; Laan, Martti; Bochkov, Yury A.; Aab, Alar; Magilnick, Nathaniel; Pooga, Margus; Gern, James E.; Johnston, Sebastian L.; Coquet, Jonathan M.; Boldin, Mark P.; Wengel, Jesper; Altraja, Alan; Bochenek, Grazyna; Jakiela, Bogdan; Rebane, Ana. Dual role of the miR-146 family in rhinovirus-induced airway inflammation and allergic asthma exacerbation. Clin Transl Med. (2021), 11, e427. [Open Access]
5. Pereira, Sara; Yao, Ruwei; Gomes, Mariana; Jørgensen, Per T.; Wengel, Jesper; Azevedo, Nuno F.;Santos, Rita S. Can vitamin B12 assist the internalization of antisense LNA oligonucleotides into bacteria? Antibiotics (2021), 10, 379. [Abstract]
4. Beck, Kasper M.; Ruder, Linette; Nicolai, Tine S.; Pham, Robert L.; Risgaard, Nikolaj A.; Hornum, Mick; Nielsen, Poul. Double-headed nucleotides with non-native nucleobases: Synthesis and duplex studies. European Journal of Organic Chemistry (2021), 2021(12), 1949-1957. [Abstract]
3.Maas, Marijn N.; Hintzen, Jordi C. J.; Löffler, Philipp M. G.; Mecinović, Jasmin. Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides. Chem. Commun., (2021), 57, 3283-3286. [Abstract]
2. Hornum, Mick; Mulberg, Mads W.; Szomek, Maria; Reinholdt, Peter; Brewer, Jonathan R.; Wustner, Daniel; Kongsted, Jacob; Nielsen, Poul. Substituted 9-diethylaminobenzo[a]phenoxazin-5-ones (Nile Red Analogues): Synthesis and photophysical properties. Journal of Organic Chemistry (2021), 86(2), 1471-1488. [Abstract]
1. Danielsen, Mathias B; Christensen, Niels Johan; Jørgensen, Per T; Jensen, Knud J; Wengel, Jesper; Lou, Chenguang. Polyamine-Functionalized 2'-Amino-LNA in oligonucleotides: Facile synthesis of new monomers and high-affinity binding towards ssDNA and dsDNA. Chemistry - A European Journal (2021), 27(4), 1416-1422. [Abstract]
