Trine Vestergaard Dam is a Masters student in the research group of Lars Grøntved. Her master’s thesis project entails work with mouse liver tissue in order to set up an experimental procedure that allows separation of the hepatocyte nuclei population and the non-hepatocyte nuclei population. By analyzing the two separated nuclei fractions by single nuclei RNA sequencing , this should provide a better resolution of e.g. rare non-hepatocyte cell populations in the liver, and possibly allow identification of novel cell types important for liver tissue function.To achieve this, she uses transgenic mice strains combined with fluorescence-activated cell sorting (FACS) or bead-based affinity purification. Trine finishes her Master's project in Summer 2019.