Declaration of interest regarding PhD project:
The Department of Neurobiology Research, Institute of Molecular Medicine at SDU is looking for applicants for a PhD scholarship within the field of Neuroscience.
We are looking for a person with a relevant degree in Biomedicine, Molecular Biology, Human Biology, or Medicine (MSc or MD)
Research environment
In our laboratory we are studying cardiometabolic diseases, such as stroke to try to understand the cellular and molecular mechanisms that contribute to impaired functional outcome. We have primarily one main research objective, which is to study the neuro-inflammatory response that occurs following ischemic stroke with the aim to contribute to the development of novel therapies for stroke and SCI patients.
Project description
Ischemic stroke (IS) is a leading cause of death and disability worldwide. Early reperfusion is imperative to improve the final clinical outcome. However, this re-establishment is only offered to <5% of all patients and initiates a cascade of complex responses that lead to chronic inflammation. In this proposal, we aim to pave the way for a paradigm shift in IS treatment, centered on the vision that active resolution of post-stroke inflammation and improved remyelination processes can be obtained by blocking detrimental and boosting pro-regenerative inflammatory processes. We will use selective anti-inflammatory therapeutics to study the effect of treatment on functional outcome and cellular and molecular changes in microglia and leukocytes in human and murine IS. We will use state-of the art techniques and believe that the results will lead to significant clinical benefits, by extending the therapeutic window for intervention and enabling a more efficacious, flexible, and safer treatment of IS.
Qualifications
The candidate must hold a relevant degree in Biomedicine, Molecular Biology, Human Biology, or Medicine and must be certified to work with laboratory animals. Experience with basic research is a prerequisite and the candidate is expected to fulfil the criteria for enrolment as a Ph.D. student at the University of Southern Denmark. For more information, please visit:
Experience with animal models for ischemic stroke and behavioural tests is an advantage. The candidate is expected to have experience with molecular techniques, such as qPCR, ELISA, and Western blotting. Experience with immunohistochemistry, immunofluorescence, in vitro cell cultures, and bioinformatics is an advantage.
The candidate is expected to spend time at Stanford University, CA, USA, and therefore must meet the criteria for obtaining a non-immigrant work visa to the USA.
For further information about the project, please contact:
Professor Kate Lykke Lambertsen
Department of Neurobiology Research
Institute of Molecular Medicine
University of Southern Denmark (SDU)
Tlf. +45 6550 3806 E-mail: klambertsen@health.sdu.dk
Applications must include:
- At letter stating the interest, motivation and qualifications for the project (max. 2 pages)
- Detailed CV, including personal contact information
- Certified copy of diploma (Master’s degree in a relevant field)
- In the field "Projektbeskrivelse" please upload an empty document
Applications must be submitted electronically using the link "Apply online".
Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Closing date June 1, 2023
Successful candidates will be asked to send an application to the PhD Secretariat, Faculty of Health Sciences, to be enrolled as PhD students.
The PhD programme will be carried out in accordance with Faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order)
The terms of employment as a salaried PhD Research Fellow are stated in the Agreement between the Ministry of Finance and the Danish Confederation of Professional Associations (AC).
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.