Clinical Physiology and Nuclear Medicine

This research unit is situated in the Department of Nuclear Medicine at Odense University Hospital (OUH) and is engaged in research and development (R & D) in the clinical physiological / nuclear medicine field by its own research, and both clinically and basic scientific research, mostly in collaboration with clinical hospital departments and institutes, departments ,and centers at the University of Southern Denmark (SDU) as well as national and international partners.

The unit applies often large scale equipment, which is also used for functional diagnostic examinations and molecular imaging in the daily clinical routine in which the discipline services most departments at Odense University Hospital (OUH) and Svendborg Hospital and a number of departments at other hospitals in the Region of Southern Denmark besides many specialists and general practitioners throughout the region.

The unit has within the frame of the Department of Nuclear Medicine access to imaging and non-imaging examination equipment, including 8 gamma cameras, 1 SPECT / CT and 4 PET / CT scanners and to its own cyclotron, radiopharmaceutical and radiochemical laboratories, etc. Furthermore , a cell laboratory for investigation of cellular uptake of and response to diagnostic and therapeutic radiopharmaceuticals. In collaboration with the Biomedical Laboratory, SDU, the unit has established a series of experiments in pigs and operates from the autumn 2011, a small animal PET/CT scanner, which is also an element of the Danish Molecular Bioimaging Center (DaMBIC) at the SDU.

The unit has in recent years focused on targeted radioisotope therapy of cancer within a center without walls named “CRIS” for Centre for Radioisotope Strategies in Cancer, which includes the department's largest research effort called “TRITON”, which stand for Targeted RadioIsotope Treatment of Neoplasms. This is a close interdisciplinary collaboration comprising primarily the Department of Physics and Chemistry at the Faculty of Science and the NanoCAN center at the Faculty of Health Sciences, SDU, besides important partners the Universities in Aarhus, Kiel, and Hamburg.

In addition to basic and statistical research the department conducts extensive research in particular cancer and heart diseases but also in disorders of the thyroid gland, adrenals, kidneys, urinary tract, and musculoskeletal system, and within arterial hypertension, diabetes, etc. In 2010, the number of publications was 44, a figure which is to be doubled within the next 3-4 years. In early 2011, the number of active research projects was 57, while the number of PhD students (from own or other units) was 7, of post-docs 3, and of Doctor of Medical Sciences 1.

The purpose of the unit’s R & D is developing, testing and implementation of new methods that can rationalize and improve patient care in a decisive way and with an emphasis on early personalized diagnostics and targeted radioisotope therapy.


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