Department of Neurobiology Research
Phone: 6550 3951
The Neuroimmunology group study pathogenic mechanisms of inflammatory diseases of the central nervous system (CNS), such as multiple sclerosis and neuromyelitis optica. Such mechanisms are often relevant to degenerative diseases such as Alzheimers disease. We mainly focus to mouse models and we use histological, flow cytometric, molecular and tissue culture methods to evaluate immuno- and neuropathogenesis in genetically-modified mice. We study interactions between the immune system and glial cells of the nervous system, both those that lead to pathology as well as with regulatory and protective outcomes. We are particularly interested in translating clinical observations to experimental analyses and we collaborate with groups in Region Syddanmark and OUH to understand how innate and adaptive immune cells and mediators contribute to neurological disease.
We are primarily funded by Forskningsstyrelsen, Scleroseforeningen, Lundbeckfonden, NovoNordiskFonden, and RegionSyddanmark.