Publications


Publications from past 5 years

Peer-reviewed original papers:

1. Amin DN, Rottenberg M, Thomsen AR, Mumba D, Fenger C, Kristensson K, Büscher P, Finsen B, Masocha W (2009) Expression and role of CXCL10 during the late encephalitic stage of experimental and clinical African trypanosomiasis. J Inf Dis. In press.

2. Lambertsen KL, Clausen BH, Babcock A, Gregersen R, Fenger C, Nielsen HH, Haugaard LS, Wirenfeldt M, Nielsen M, Dagnaes-Hansen F, Bluethmann H, Færgeman NJ, Meldgaard M, Deierborg T, Finsen B (2009) Microglia protect neurons against ischemia by synthesis of tumor necrosis factor. J Neurosci. 29:1319-1330.

3. Nielsen M, Lambertsen KL, Clausen BH, Meldgaard M, Diemer NH, Zimmer J, Finsen B. Nuclear Translocation of endonuclease G in degenerating neurons after permanent middle cerebral artery occlusion in mice. Exp Brain Res. 194:17-27.

4. Christensen JE, Simonsen S, Fenger C, Sørensen MR, Moos T, Christensen JP, Finsen B, Thomsen AR (2009) Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade. J Immunol. 182:1079-1087.

5. Clausen BH*, Lambertsen KL*, Babcock AA, Holm T, Dagnaes-Hansen F, Finsen B (2008) Interleukin-1β and tumor necrosis factor-a are expressed by different subsets of microglia and macrophages after ischemic stroke in mice. J Neuroinflam. 5:46 (18 pp). *Shared 1st authorship.

6. Dissing-Olesen L, Thaysen-Andersen M, Meldgaard M, Højrup P, Finsen B (2008) The function of the human interferon-beta 1a glycan determined in vivo. J Pharm Exp Ther 326:338-347.

7. Lyck L, Dalmau I, Chemnitz J, Finsen B, Schrøder HD (2008) Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex. J Histochem Cytochem 56:201-221.

8. Degn M, Lambertsen KL, Petersen G, Meldgaard M, Artmann A, Clausen BH, Hansen SB, Finsen B, Hansen HS, Lund TM (2007) Changes in brain levels of N-acylethanolamines and 2-arachidonoyl glycerol in focal cerebral ischemia in mice. J Neurochem 103:1907-1916.

9. Dissing-Olesen L, Ladeby R, Nielsen HH, Toft-Hansen H, Dalmau I, Finsen B (2007) Axonal lesion-induced microglial proliferation and microglial cluster formation in the mouse. Neurosci 149:112-122.

10. Lambertsen KL, Clausen BH, Fenger C, Meldgaard M, Wullf H, Finsen B (2007) Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice. Neurosci 144:934-949.

11. Lyck L, Krøigaard T, Finsen B (2007) Recruitment of neurons and myelinating cells to the murine neocortex during postnatal development. Eur J Neurosci 26:1749-1764.

12. Wirenfeldt M, Dissing-Olesen L, Babcock AA, Nielsen M, Meldgaard M, Zimmer J, Azcoitia I, Leslie RGQ, Dagnæs-Hansen F, Finsen B (2007) Population control of resident and immigrating microglia by mitosis and apoptosis. Am J Pathol 171:17-31.

13. Babcock AA, Wirenfeldt M, Holm T, Nielsen HH, Dissing-Olesen L, Toft-Hansen H, Millward J, Landmann R, Rivest S, Finsen B, Owens T (2006) Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation. J Neurosci 26:12826-12837.

14. Clausen BH, Lambertsen KL, Finsen B (2006) Glyceraldehyde-3-phosphate dehydrogenase versus toluidine blue as a marker for infarct volume estimation following permanent middle cerebral artery occlusion in mice. Exp Brain Res 175:60-67.

15. Cumming P, Pedersen MD, Minuzzi L, Mezzomo K, Danielsen EH, Iversen P, Aagaard D, Keiding M, Munk OL, Finsen B (2006) Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography. Synapse 59:418-426.

16. Fenger C, Drøjdahl N, Wirenfeldt M, Sylvest L, Jørgensen OS, Meldgaard M, Lambertsen K, Finsen B (2006) Tumor necrosis factor or its TNFp55 and -p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata. Glia 54:591-605.

17. Lyck L, Jelsing J, Jensen PS, Lambertsen KL, Pakkenberg B, Finsen B (2006) Immunohistochemical visualization of neurons and specific glial cells in the porcine neocortex for stereological application. J Neurosci Meth 152:229-242.

18. Meldgaard M, Fenger C, Pedersen MD, Ladeby R, Lambertsen KL, Finsen B (2006) Validation of two reference genes for mRNA level studies of murine disease models in neurobiology. J Neurosci Meth 156:101-110.

19. Müller GJ, Dogonowski A-M, Finsen B, Johansen FF (2006) Expression of glutamic acid decarboxylase and identification of GABAergic cells in the ischemic rat dentate gyrus. Exp Brain Res 175:556-566.

20. Nielsen HH, Ladeby R, Drøjdahl N, Peterson AC, Finsen B (2006) Oligodendrocyte precursor cells proliferate in response to acute axonal degeneration in adult mouse central nervous system. Glia 54:105-115.

21. Pedersen MD, Minuzzi L, Wirenfeldt M, Meldgaard M, Slidsborg C, Cumming P, Finsen B (2006) Upregulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activition in the mouse. Eur J Neurosci 24:991-1000.

22. Clausen BH, Lambertsen KL, Meldgaard M, Finsen B (2005) A quantitative in situ hybridization and polymerase chain reaction study of microglial-macrophage expression of IL-1b mRNA following middle cerebral artery occlusion in mice. Neurosci 132:879-892.

23. Ladeby R, Wirenfeldt Nielsen M, Ovejero DG, Gregersen R, Dalmau I, Finsen B (2005) Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury. Glia 50:121-131.

24. Lambertsen KL, Meldgaard M, Ladeby R, Finsen B (2005) A quantitative study of microglial-macrophage synthesis of tumour necrosis factor during acute and late focal cerebral ischemia in mice. J Cereb Blood Flow Metab 25:119-135.

25. Wirenfeldt M, Babcock AA, Ladeby R, Lambertsen KL, Dagnæs-Hansen F, Leslie RGQ, Owens T, Finsen B (2005) Microglial heterogeneity in injured central nervous system. J Neurosci Res 82:507-514.

26. Drøjdahl N, Fenger C, Nielsen HH, Owens T, Finsen B (2004) Dynamics of oligodendrocyte responses and oligodendrocyte-axonal interactions in areas with Wallerian degeneration in normal and TNF-transgenic mice. J Neurosci Res 75:203-207.

27. Lambertsen KL, Gregersen R, Meldgaard M, Clausen BH, Heibøl EK, Ladeby R, Knudsen J, Frandsen Aa, Owens T, Finsen B (2004) A role for interferon-gamma in focal cerebral ischemia in mice. J Neuropathol Exp Neurol 63:942-955.

28. Meldgaard M, Bollen P, Finsen B (2004) Fast and reliable method for extraction of mouse DNA for PCR. Lab Animals 38:413-417.

29. Nielsen JV, Mitchelmore C, Pedersen KM, Kjærulff KM, Finsen B, Jensen NA (2004) FKBP8: Novel isoforms, genomic organization, and characterization of a forebrain promoter in transgenic mice. Genomics 81:181-192.


Book chapters and review papers

1. Wirenfeldt MW, Dissing-Olesen L, Babcock AA, R. Ladeby, Jensen MB, Owens T, Finsen B (2007) Microglial cell population expansion following acute neural injury. In: “Interaction between neurons and glia in aging and diseases” (eds Malva J, Cunha R, Oliveir CR), Springer, pp. 37-52.

2. Bjarkham CF, Larsen M, Wanatabe H, Röhl L, Simonsen CZ, Pedersen M, Ringgard S, Andersen F, Cumming P, Dalmose AL, Møller A, Jensen LW, Danielsen EH, Dalmau I, Finsen B, Öttingen Gv, Gjedde A, Sørensen JC (2005) A porcine model of subthalamic high-frequency deep brain stimulation in Parkinson's disease. Chapter 5 in Parkinson's Disease: New Research. Willow MJ (ed). Nova Science Publishers, New York. ISBN-1-59454-352-356.

3. Ladeby R, Wirenfeldt M, Fenger C, Dissing-Olesen L, Dalmau I, Finsen B (2005) Microglial cell population dynamics in injured adult CNS. Brain Res Rev 48:196-206

4. Wirenfeldt M, Ladeby R, Dalmau I, Finsen B (2005) Mikroglia - Biologi og Klinisk Relevans. Ugeskr Læg, 167:3025-3030.

5. Finsen B, Gregersen R, Lehrmann E, Lovmand S and West MJ (2004) In situ hybridization. In: Quantitative Methods in Neuroscience - A Neuroanatomical Approach (eds Evans SM, Janson AM, Nyengaard JR), Oxford University Press, pp 115-145.

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