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Random Mixtures can be DANGEROUS

Some chemicals shouldn't be mixed together. In fact, these chemicals shouldn't even be stored near each other on the chance that an accident could occur and the chemicals could react.  Some examples of mixtures to avoid can be found on various websites eg incompatible chemical mixtures.




Acetone (CH3COCH3) (propanone)


Concentrated sulphuric acid, nitric acid, or mixtures thereof.


Acetyl chloride ( CH3COCl ) (ethanoyl chloride)


Water or alcohols.


Acetylene (CH=CH)


Halogens, copper, silver, mercury


Alkaline ethanolates og -ethoxides




Alkali metals (Li, Na, K)


Water, carbon dioxide, carbon tetrachloride or other chlorinated hydrocarbons.


Alkaline methanolates and methoxides




Aluminium (Al)


Hydrochloric acid, warm concentrated sulfuric acid, perchloric acid, strong bases, water, carbon dioxide, carbon tetrachloride and other chlorinated hydrocarbons.
Aluminium alkyls Water.
Ammonia (NH3)


Mercury, halogens, hypochlorite and hydrofluoric acid.


Ammonium nitrate (NH4NO3)


Acids, metal powders, flammable liquids, chlorates, nitrates, nitrites, sulfur, powdered organic material.


Aniline (C6H5NH2) Nitric acid, hydrogen peroxide.
Benzol chloride (C6H5COCl) Water.
Hydrogen cyanide (HCN) Nitric acid, alkalis.
Boron compounds Water.
Boron trihalides Alcohols, water.
Bromine (Br2) Ammonia, acetylene, alkanes, alkenes, alkynes, benzene, hydrogen, sodium carbide, vegetable turpentine, metallic powders.
Calcium (Ca) Carbon dioxide, carbon tetrachloride and other chlorinated hydrocarbons, water.
Calcium oxide (CaO) (burnt lime) Water.
aktive Carbon (C) Calcium hypochlorite.
Carbonyls Water.
Chlorine (Cl2) Ammonia, acetylene, alkanes, alkenes, alkynes, benzene, hydrogen, sodium carbide, vegetable turpentine, metallic powders, water.
Chlorine sulfonic acid (ClSO2OH) Metals, water.
Chlorates (ClO3-) Ammonium salts, acids, metal powders, sulfur, carbon, powdered organic matter.
Chlorine dioxide (ClO2) Ammonia, methane, phoshine, hydrogen sulfide.


Chromic acid and chromic trioxide (CrO3) Acetic acid, naphthalene, camphor, glycerol, vegetable turpentine, alcohol, other flammable liquids.
Cyanides Acids.
Cyanogen (N=C-C=N) and cyanogen halides Water.
Diborane (B2H6) Water.
Disulfur dichloride (S2Cl2) (sulphur chloride) Water.
Acetic acid (CH3COOH) Chromic or nitric acids, compounds containing hydroxyl groups, ethylene glycol, oxidizing agents such as perchloric acid, peroxides and permanganate.
Fluorine (F2) Anything at all!
Grignard reagents Water.
Hydrazine (H2NNH2) Oxidizing substances such as hydrogen peroxide and nitric acid.
Hydrides Water, oxidizing compounds.


Hydrogen fluoride (HF) (fluoric acid) Anything at all!
Hydrogen peroxide (H2O2) Ground iron, copper, chromium, lead, silver, manganese, and salts of these metals; flammable liquids, aniline, nitromethane.
Iodine (I2) Ammonia, acetylene, alkanes, alkenes, alkynes, hydrogen, metal powders.
Isocyanate Water.
Potassium permanganate (KMnO4) Glycerol, ethylene glycol, benzaldehyde, sulfuric acid.
Copper (Cu) Acetylene, hydrogen peroxide.
Hydrocarbons Halogens, chromium trioxide, peroxides.
Mercury (Hg) and its salts Acetylene, hydrogen, ammonia.
Magnesium (Mg) Carbon dioxide, carbon tetrachloride, other chlorinated hydrocarbons, water.
Magnesium alkyls Water.
Methyl trichlorosilicane (CH3SiCl3)




Sodium nitrite (NaNO2)


Ammonium nitrate and other ammonium salts, acids.


Sodium peroxide (Na2O2) Oxide-containing materials such as methanol, ethanol, glacial acetic acid, acetic anhydride, benzaldehyde, sulfur carbon, glycerol, ethylene glycol, ethyl acetate, methyl acetate, furfural.
Sodium azide (NaN3) Water.
Nitroparaffins Inorganic amines??
Oxalic acid ((COOH)2) Silver, mercury. 
Oxygen (O2) Oils, grease, hydrogen, flammable liquids, solids or gases
Perchloric acid (HClO4) Acetic anhydride, alcohols, paper, wool, other organic material. 
Peroxides, organic Acids (mineral or organic)
Phosphorus, yellow Air, halogens, corrosive bases, reducing agents.
Phosphorus, white Air, oxygen, corrosive bases, reducing agents.
Phosphoric nitrides Water.
Phosphorus oxyhalides Water.
Phosphorus pentoxide (P2O5) Water.
Phosphorus trihalides and -pentahalides Water.
Propionyl chloride (CH3CH2COCl) Water, alkohols.
Nitric acid (HNO3) Acetic acid, acetone, alcohols, aniline, hydrogen cyanide, chromium trioxide, hydrogen sulfide, combustible organic matter, copper, zinc, nitrogen containing compounds.
Silicon tetrachloride (SiCl4) (tetrachlorosilane) Water, alcohols.
Sulfuryl chloride (SO2Cl2) (sulfonyl chloride) Water, bases.
Sulfur (S) (Sulphur) Chlorates, perchlorates.
Sulfur dichloride (SCl2) Water, alcohols.
Sulfuric acid (H2SO4) or oleum Chlorates, perchlorates, permanganates, water.
Sulfur tetrachloride (SCl4) Water.
Silver (Ag) and its salts Acetylene, hydrogen, oxalic acid, tartaric acid, ammonia, ammonium salts.


Thionyl chloride (SOCl2)




Titanium tetrachloride (TiCl4)




Zinc (Zn)




Zinc alkyls




Tosyl isocyanates (CH3C6H4SO2-isocyanate) Water.

Last Updated 09.08.2023