Research publications 2008-12

Adegboye ARA, Christensen LB, Holm-Pedersen, Avlund K, Boucher BJ, Heitmann BL.
Intake of dairy products in relation to periodontitis in older adults.
Nutrients 2012 Sep; 4: 1219-29. Pubmed abstract

Andersen PS, Pedersen JK, Fode P, Skov RL, Fowler VG Jr, Stegger M, Christensen K.
Influence of host genetics and environment on nasal carriage of staphylococcus aureus in Danish middle-aged and elderly twins.
J Infect Dis. 2012 Oct;206(8):1178-84. Pubmed abstract

Avlund K.
Livsforløb og aldring af bevægeapparatet.
[Life and aging of the musculoskeletal system]
Gerontologi. 2012; 29: 4-6.

Avlund K, Hokland M, Mehlsen MY, Thomsen DK, Viidik A, Ekmann A, Zachariae R.
Differential associations between white blood cell counts and fatigue in young and older adults.
Aging Clin Exp Res. 2012 Oct;24(5):439-47. Pubmed abstract

Barral S, Cosentino S, Costa R, Matteini A, Christensen K, Andersen SL, Glynn NW, Newman AB, Mayeux R.
Cognitive function in families with exceptional survival.
Neurobiol Aging. 2012 Mar; 33(3):619.e1-7. Pubmed abstract

Brühl A, Avlund K.
Structural validity and internal consistency of functional ability scales for healthy older people in Germany.
J Clin Gerontol Geriatr. 2012; 3: 29-35.

Christensen K, McGue M.
Commentary: Twins, worms and life course epidemiology.
Int J Epidemiol. 2012 Aug;41(4):1010-1.

Christensen K, Pedersen JK, Hjelmborg JV, Vaupel JW, Stevnsner T, Holm NV, Skytthe A.
Cancer and longevity - Is there a trade-off? A study of co-occurrence in Danish twin pairs born 1900-1918.
J Gerontol A Biol Sci Med Sci 2012 May;67(5):489-94. Pubmed abstract

Dato S, Montesanto A, Lagani V, Jeune B, Christensen K, Passarino G.
Frailty phenotypes in the elderly based on cluster analysis: A longitudinal study of two Danish cohorts. Evidence for a genetic influence on frailty.
Age (Dordr). 2012 Jun;34(3):571-82. Pubmed abstract

Dato S, Soerensen M, Montesanto A, Lagani V, Passarino G, Christensen K, Christiansen L.
UCP3 polymorphisms, hand grip performance and survival at old age: Association analysis in two Danish middle aged and elderly cohorts.
Mech Ageing Dev. 2012 Aug;133(8):530-7. Pubmed abstract

Ekmann A, Avlund K, Osler M, Lund R.
Do negative aspects of social relations influence fatigue? A cross-sectional study on a non-clinical sample of middle-aged Danish men.
J Psychosom Res. 2012 Okt;73(4):277-82. Pubmed abstract

Ekmann A, Osler M, Avlund K.
The predictive value of fatique for nonfatal ischemic heart disease and all-cause mortality.
Psychosom Med. 2012 Jun;74(5):464-70. Pubmed abstract

Gow AJ, Mortensen EL, Avlund K.
Activity participation and cognitive ageing in the Glostrup 1914 cohort from age 50 to 85.
J Am Geriatr Soc. 2012 Oct;60(10):1831-8. Pubmed abstract

Gredilla R, Garm C, Stevnsner T.
Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems.
Oxid Med Cell Longev. 2012;2012:282438. Pubmed abstract

Gredilla R, Stevnsner T.
Mitochondrial base excision repair assays.
Methods Mol Biol. 2012;920:289-304. Pubmed abstract

Gredilla R, Weissman L, Yang JL, Bohr VA, Stevnsner T.
Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer’s disease.
Neurobiol Aging. 2012 Apr;33(4):694-707. Pubmed abstract

Harbo M, Bendix L, Bay-Jensen AC, Graakjaer J, Søe K, Andersen TL, Kjaersgaard-Andersen P, Koelvraa S, Delaisse JM.
The distribution pattern of critically short telomeres in human osteoarthritic knees.
Arthritis Res Ther. 2012 Jan 18;14(1):R12. Pubmed abstract

Ibfelt E, Kjaer SK, Johansen C, Høgdall C, Steding-Jessen M, Frederiksen K, Frederiksen BL, Osler M, Dalton SO.
Socioeconomic position and stage of cervical cancer in Danish women diagnosed 2005-2009.
Cancer Epidemiol Biomarkers Prev. 2012 May;21(5):835-42. Pubmed abstract

Jeune B et al.
A new vision for old age: Rethinking health policy for Europe's ageing society.
Red. Chipman A, Kielstra P, Scott I, Webber C.
Economist Intelligence Unit report. 2012 Jan.

Kamer AR, Morse DE, Holm-Pedersen P, Mortensen EL, Avlund K.
Periodontal inflammation in relation to cognitive function in an older adult Danish population.
J Alzheimers Dis. 2012; 28(3):613-24. Pubmed abstract

Mangino M, Hwang SJ, Spector TD, Hunt SC, Kimura M, Fitzpatrick AL, Christiansen L, Petersen I, Elbers CC, Harris T, Chen W, Srinivasan SR, Kark JD, Benetos A, El Shamieh S, Visvikis-Siest S, Christensen K, Berenson GS, Valdes AM, Viñuela A, Garcia M, Arnett DK, Broeckel U, Province MA, Pankow JS, Kammerer C, Liu Y, Nalls M, Tishkoff S, Thomas F, Ziv E, Psaty BM, Bis JC, Rotter JI, Taylor KD, Smith E, Schork NJ, Levy D, Aviv A.
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.
Hum Mol Genet. 2012 Dec;21(24):5385-94. Pubmed abstract

Mengel-From J, Mengel-From J, Thinggaard M, Christiansen L, Vaupel JW, Orstavik KH, Christensen K.
Skewed X inactivation and survival: a 13-year follow-up study of elderly twins and singletons.
Eur J Hum Genet. 2012 Mar;20(3):361-4. Pubmed abstract

Mortensen El, Barefoot J, Avlund K.
Do depressive traits and hostility predict age-related decline in general intelligence?
J Aging Res. 2012;2012:973121. Pubmed abstract

Mänty M, Ekmann A, Thinggaard M, Christensen K, Avlund K.
Fatigability in basic indoor mobility in nonagenarians.
J Am Geriatr Soc. 2012.;60: 1279-85. Pubmed abstract

Mänty M, Mendes de Leon C, Rantanen T, Era P, Pedersen AN, Ekmann A, Schroll M, Avlund K.
Mobility-related fatigue, walking speed and muscle strength in older people.
J Gerontol A Biol Sci Med Sci. 2012; 67A: 523-9. Pubmed abstract

Møller A, Mortensen OS, Reventlow S, Skov PG, Andersen JH, Rubak TS, Hansen ÅM, Andersen LL, Lund R, Osler M, Christensen U, Avlund K.
Life time occupational physical activity and musculoskeletal ageing in middle-aged men and women in Denmark. Retrospective Cohort Study Protocol and Methods.
JMIR Research Protocols 2012; 1, 2:7.

Møller A, Reventlow S, Andersen JH, Avlund K, Mortensen OS.
Validity of workers’ self-reports. Evaluation of a question assessing lifetime exposure to occupational physical activity.
British Journal of Medicine and Medical Research 2012; 2: 536-52.

Nybo M, Jeune B, Andersen-Ranberg K.
Natriuretic peptide concentrations in centenarians.
J Am Geriatr Soc. 2012 May;60(5):991-3.

Poulsen T, Siersma VD, Lund R, Christensen U, Vass M, Avlund K.
Impact of social capital on 8 year mortality among older people in 34 Danish municipalities.
J Aging Health 2012 Oct;24(7):1203-22. Pubmed abstract

Rodríguez Lopez S, Nilsson C, Lund R, Montero P, Fernández-Ballesteros R, Avlund K.
Social inequality in dynamic balance performance in an early old age Spanish population: the role of health and life style associated factors.
Arch Gerontol Geriatr 2012 Mar-Apr;54(2):e139-45. Pubmed abstract

Sørensen, M.
Genetic Variation and Human Longevity. Association studies of DNA repair, GH/IGF-1/insulin signaling, oxidative stress and classical candidate genes.
Ph.d.-afhandling 2012 Mar; Syddansk Universitet.

Soerensen M.
Genetic variation and human longevity.
Dan Med J. 2012 May;59(5):B4454. Pubmed abstract

Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Jacobsen R, Suchiman HE, de Craen AJ, Westendorp RG, Schreiber S, Stevnsner T, Bohr VA, Slagboom PE, Nebel A, Vaupel JW, Christensen K, McGue M, Christiansen L.
Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: Cross sectional and longitudinal studies.
Exp Gerontol. 2012 May;47(5):379-87. Pubmed abstract

Soerensen M, Thinggaard M, Nygaard M, Dato S, Tan Q, Hjelmborg J, Andersen-Ranberg K, Stevnsner T, Bohr VA, Kimura M, Aviv A, Christensen K, Christiansen L.
Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis.
Aging Cell. 2012 Apr;11(2):223-7. Pubmed abstract

Talens RP, Christensen K, Putter H, Willemsen G, Christiansen L, Kremer D, Suchiman HE, Slagboom PE, Boomsma DI, Heijmans BT.
Epigenetic variation during the adult lifespan: Cross-sectional and longitudinal data on monozygotic twin pairs.
Aging Cell. 2012 Aug;11(4):694-703. Pubmed abstract

Thier S, Lorenz D, Nothnagel M, Poremba C, Papengut F, Appenzeller S, Paschen S, Hofschulte F, Hussl AC, Hering S, Poewe W, Asmus F, Gasser T, Schöls L, Christensen K, Nebel A, Schreiber S, Klebe S, Deuschl G, Kuhlenbäumer G.
Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor.
Neurology. 2012 Jul 17;79(3):243-8. Pubmed abstract

Tiainen K, Thinggaard M, Jylhä M, Bladbjerg E, Christensen K, Christiansen L.
Associations between inflammatory markers, candidate polymorphisms and physical performance in older Danish twins.
Exp Gerontol. 2012 Jan;47(1):109-15. Pubmed abstract

Wu Y, Zhang D, Pang Z, Oksuzyan A, Jiang W, Wang S, Li S, Kruse T, Christensen K, Tan Q.
Gender-specific patterns in age-related decline in general health among Danish and Chinese: A cross-national comparative study.
Geriatr Gerontol Int. 2012 Jul; 12(3):431-9. Pubmed abstract

Yamada Y, Ekmann A, Nilsson CJ, Vass M, Avlund K.
Are acceptance rates of a national preventive home visit programme for older people socially imbalanced?
BMC Public Health 2012 Jun; 12: 396. Pubmed abstract

Yamada Y, Siersma V, Avlund K, Vass M.
Formal home help services and institutionalization.
Arch Gerontol Geriatr. 2012 Mar-Apr;54(2):e52-6. Pubmed abstract

2011:

Avlund K, Schultz-Larsen K, Christiansen N, Holm-Pedersen P.
Number of teeth and fatigue in older adults.
J Am Geriatr Soc. 2011 Aug;59(8):1459-64. Pubmed abstract

Behrman JR, Kohler HP, Jensen VM, Pedersen D, Petersen I, Bingley P, Christensen K.
Does more schooling reduce hospitalization and delay mortality? New evidence based on Danish twins.
Demography 2011 Nov;48(4):1347-75. Pubmed abstract

Bendix L, Gade MM, Staun PW, Kimura M, Jeune B, Hjelmborg JV, Aviv A, Christensen K.
Leukocyte telomere length and physical ability among Danish Twins age 70+.
Mech Age Dev. 2011 Nov;132(11-12):568-72. Pubmed abstract

van den Berg GJ, Doblhammer-Reiter G, Christensen K.
Being born under adverse economic conditions leads to a higher cardiovascular mortality rate later in life: Evidence based on individuals born at different stages of the business cycle.
Demography 2011 Maj;48(2):507-30. Pubmed abstract

Birnie K, Cooper R, Martin RM, Kuh D, Aihie Sayer A, Alvarado BE, Bayer A, Christensen K, Cho S, Cooper C, Corley J, Craig L, Deary IJ, Demakakos P, Ebrahim S, Gallacher J, Gow AJ, Gunnell D, Haas S, Hemmingsson T, Inskip H, Jang S, Noronha K, Osler M, Palloni A, Rasmussen F, Santos-Eggimann B, Spagnoli J, Starr J, Steptoe A, Syddall H, Tynelius P, Weir D, Whalley LJ, Zunzunegui MV, Ben-Shlomo Y, Hardy R on behalf of the HALCyon study team.
Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis.
PLoS One 2011 Jan 26;6(1):e15564. Pubmed abstract

Brasch-Andersen C, Møller MU, Christiansen L, Thinggaard M, Otto M, Brøsen K, Sindrup SH.
A candidate gene study of serotonergic pathway genes and pain relief during treatment with escitalopram in patients with neuropathic pain shows significant association to serotonin receptor2C (HTR2C).
Eur J Clin Pharmacol. 2011 Nov;67(11):1131-7. Pubmed abstract

Christensen BS, Grønbaek M, Osler M, Pedersen BV, Graugaard C, Frisch M.
Associations between physical and mental health problems and sexual dysfunctions in sexually active Danes.
J Sex Med. 2011 Jul;8(7):1890-902. Pubmed abstract

Christensen K, Vaupel JW.
Genetic factors and adult mortality.
In:International Handbook of Population: International Handbook of Adult Mortality, red. Rogers RG, Crimmins EM.
Springer 2011, Vol. 2, s. 399-410.

Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van de Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE.
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Aging Cell. 2011 Aug;10(4):686-98. Pubmed abstract

Doty RL, Petersen I, Mensah N, Christensen K.
Genetic and environmental influences on odor identification ability in the very old.
Psychol Aging. 2011 Dec;26(4):864-71. Pubmed abstract

Erlangsen A, Nordentoft M, Conwell Y, Waern M, De Leo D, Lindner R, Oyama H, Sakashita T, Andersen-Ranberg K, Quinnett P, Drager B, Lapierre S.
Key considerations for preventing suicide in older adults: Consensus opinions of an expert panel.
Crisis. 2011;32(2):106-9. Pubmed abstract

Heegaard K, Avlund K, Holm-Pedersen P, Hvidtfeldt UA, Bardow A, Grønbæk M.
Amount and type of alcohol consumption and missing teeth among community dwelling older adults. Findings from the Copenhagen Oral Health Senior Study.
J Public Health Dentistry. 2011; 71: 318-26. Pubmed abstract

Heegaard K, Bardow A, Holm-Pedersen P, Hvidtfeldt U, Grønbæk M, Avlund K.
The Copenhagen Oral Health Senior Cohort. Design, population and dental health.
Gerodontology. 2011 Sep;28(3):165-76. Pubmed abstract

Hendriksen C, Avlund K.
Funktionsevnemålinger.
[Measurements of functionality.]
In:Modvig J, Jensen BT, Nielsen Cv (eds). Lærebog i Klinisk Socialmedicin og Rehabilitering. FADL’s Forlag 2011; 64-80.

Jeppesen DK, Bohr VA, Stevnsner T.
DNA repair deficiency in neurodegeneration.
Prog Neurobiol. 2011 Jul;94(2):166-200. Pubmed abstract

Jeune B.
Lever vi både længere og bedre?
[Are we living both longer and better?]
Ældreviden.
Alderens nye sider. Tema: Fremtidens ældreomsorg, 2011 Jan:8-9.

Jeune B.
Ældre borgere som ressource: Medborgerskab i et aktivt ældreliv - fra ældrebyrde til ældrestyrke.
[Older citizens as a resource: Citizenship in an active later life - from burden to might.]
Danske Ældreråd,
Konferencerapport; 2011 Jun.

Kriegbaum M, Christensen U, Osler M, Lund R.
Excessive drinking and history of unemployment and cohabitation in Danish men born in 1953.
Eur J Public Health. 2011 Aug;21(4):444-8. Pubmed abstract

Kulminski AM, Arbeev KG, Christensen K, Mayeux R, Newman AB, Province MA, Hadley EC, Rossi W, Perls TT, Elo IT, Yashin AI.
Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits.
Mech Ageing Dev. 2011 Apr;132(4):195-201. Pubmed abstract

Kriegbaum M, Larsen AM, Christensen U, Lund R, Osler M.
Reduced probability of smoking cessation in men with increasing number of job losses and partnership breakdowns.
J Epidemiol Community Health. 2011 Jun;65(6):511-6. Pubmed abstract

Larsen AM, Lund R, Kriegbaum M, Avlund K, Osler M.
Childhood social circumstances and body mass index in adult life: The Metropolit 1953 Danish male birth cohort.
Scand J Public Health. 2011 May;39(3):296-302. Pubmed abstract

Madsen M.
Social Inequality in Health - A discordant Twin-Pair Design
Ph.d.-afhandling 2011 Nov; Syddansk Universitet.

Madsen M, Andersen PK, Gerster M, Nybo Andersen AM, Christensen K, Osler M.
Does the association of education with breast cancer replicate within twin pairs? A register-based study on Danish female twins.
Br J Cancer. 2011 Feb;104(3):520-3. Pubmed abstract

Mengel-From J, Christensen K, Thinggaard M, McGue M, Christiansen L.
Genetic variants in the choline acetyltransferase (ChAT) gene are modestly associated with normal cognitive function in the elderly.
Genes Brain Behav. 2011 Nov;10(8):876-82. Pubmed abstract

Mengel-From J, Christensen K, McGue M, Christiansen L.
Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.
Neurobiol Aging. 2011 Mar;32(3):554.e7-11. Pubmed abstract

Mortensen LH, Maier AB, Slagbom PE, Pawelec G, Derhovanessian E, Petersen I, Jahn G, Westendorp RG, Christensen K.
Early-life environment influencing susceptibility to cytomegalovirus infection: Evidence from the Leiden Longevity Study and the Longitudinal Study of Aging Danish Twins. 
Epidemiol Infect. 2011 Jul 25:1-7. Pubmed abstract

Nilsson C, Avlund K, Lund R.
Onset of mobility limitations in old age. The combined effects of socioeconomic position and social relations.
Age Ageing. 2011 Seo;40(5):607-14. Pubmed abstract

Nilsson CJ, Avlund K, Lund R.
Social inequality in onset of mobility limitations in midlife – a longitudinal study in Denmark.
Eur J Aging. 2011;8:255-232.

Oksuzyan A, Jacobsen R, Glaser K, Tomassini C, Vaupel JW, Christensen K.
Sex differences in medication and primary healthcare use before and after spousal bereavement at older ages in Denmark: Nationwide register study of over 6000 bereavements.
J Aging Res. 2011;2011:678289. Pubmed abstract

Osler M, Linneberg A, Glümer C, Jørgensen T.
The cohorts at the Research Centre for Prevention and Health, formerly 'The Glostrup Population Studies'.
Int J Epidemiol. 2011 Jun;40(3):602-10.

Osler M, Nybo Andersen AM.
Livsforløb og helbred.
In: Lund R, Christensen U, Iversen (eds).
[Life course and health.]
Medicinsk Sociologi.
Munksgaard 2011. Munksgaard Denmark...

Patro BS, Hougaard RF, Bohr VA, Stevnsner T.
WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.
J Cell Sci. 2011 Dec;124(Pt 23):3967-79. Pubmed abstract

Petersen I.
Twin-singleton differences in Denmark in the 20th Century: A comparison of school achievement, male height, marital status, and diabetes between twins and singletons.
Ph.d. afhandling. 2011 Maj; Syddansk Universitet.

Petersen I, Nielsen MM, Beck-Nielsen H, Christensen K.
No evidence of a higher 10 year period prevalence of diabetes among 77,885 twins compared with 215,264 singletons from the Danish birth cohorts 1910-1989.
Diabetologia. 2011 Aug;54(8):2016-24. Pubmed abstract

Petersen LLB, Jeune B.
Icons of Longevity. Luxdorph's Eighteens Century Gallery of Long-livers.
Syddansk Universitetsforlag. 2011:1-330. Universitypress...

Poulsen T, Christensen U, Lund R, Avlund K.
Measuring aspects of social capital in a gerontological perspective.
Eur J Aging. 2011;8:221-232. Springer link...

Risnes KR, Vatten LJ, Baker JL, Jameson K, Sovio U, Kajantie E, Osler M, Morley R, Jokela M, Painter RC, Sundh V, Jacobsen GW, Eriksson JG, Sørensen TI, Bracken MB.
Birthweight and mortality in adulthood: A systematic review and meta-analysis.
Int J Epidemiol. 2011 Jun;40(3):647-61. Pubmed abstract

Sadler ME, Miller CJ, Christensen K, McGue M.
Subjective wellbeing and longevity: A co-twin control study.
Twin Res Hum Genet. 2011 Jun;14(3):249-56. Pubmed abstract

Skytthe A, Valensin S, Jeune B, Cevenini E, Balard F, Beekman M, Bezrukov V, Blanche H, Bolund L, Broczek K, Carru C, Christensen K, Christiansen L, Collerton JC, Cotichini R, de Craen AJ, Dato S, Davies K, De Benedictis G, Deiana L, Flachsbart F, Gampe J, Gilbault C, Gonos ES, Haimes E, Hervonen A, Hurme MA, Janiszewska D, Jylhä M, Kirkwood TB, Kristensen P, Laiho P, Leon A, Marchisio A, Masciulli R, Nebel A, Passarino G, Pelicci G, Peltonen L, Perola M, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Scurti M, Sevini F, Sikora E, Skouteri A, Slagboom PE, Spazzafumo L, Stazi MA, Toccaceli V, Toussaint O, Törnwall O,Vaupel JW, Voutetakis K, Franceschi C; for the GEHA consortium.
Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project.
Exp Gerontol. 2011 Nov;46(11):934-45. Pubmed abstract

Tan Q, Thomassen M, Hjelmborg JV, Clemmensen A, Andersen KE, Petersen TK, McGue M, Christensen K, Kruse TA.
A growth curve model with fractional polynomials for analysing incomplete time-course data in microarray gene expression studies.
Adv Bioinformatics. 2011;2011:261514. Pubmed abstract

Thier S, Kuhlenbäumer G, Lorenz D, Nothnagel M, Nebel A, Christensen K, Schreiber S, Deuschl G, Klebe S.
GABA(A) receptor- and GABA transporter polymorphisms and risk for essential tremor.
Eur J Neurol. 2011 Aug;18(8):1098-100. Pubmed abstract

Venoe S, Kulikowicz T, Pestana C, Stepien P, Stevnsner T, Bohr V.
The human Suv3 helicase interacts with replication protein A and flap endonuclease 1 in the nucleus.
Biochemical Journ. 2011;440, 293-300. Pubmed abstract

Yamada Y, Vass M, Hvas L, Igarashi A, Hendriksen C, Avlund K.
Collaborative relationship in preventing home visits to older people.
Int J Older People Nurs. 2011 Mar;6(1):33-40. Pubmed abstract

2010:

Avlund K.
Fatigue in older adults: An early indicator of the aging process.
Aging Clin Exp Res. 2010 Apr;22(2):100-15. Pubmed abstract

Avlund K.
Muskel- og skeletsygdomme hos gamle mennesker.
[Musculoskeletal diseases among older people]
In: Danneskiold-Samsøe B, Lund H, Wahrens E (red). Klinisk reumatologi for ergoterapeuter og fysioterapeuter – 2. udgave. Munksgaard Danmark, 2011: 27-32.

Bendix L, Horn PB, Jensen UB, Rubelj I, Kolvraa S.
The load of short telomeres, estimated by a new method, Universal STELA, correlates with number of senescent cells.
Aging Cell. 2010 Jun;9(3):383-97. Pubmed abstract

Bendix L, Kølvraa S.
Telomerers rolle ved aldringsbetingede sygdomme.
[The role of telomeres in aging-related disease]
Ugeskrift for Læger.
2010 Okt 4;172(40):2752-5.

Bendix L, Kølvraa S.
Telomerers rolle i cancer.
[The role of telomeres in cancer]
Ugeskrift for Læger.
2010 Okt 4;172(40):2748-51.

Bendix L, Kølvraa S.
Telomerer og telomerase.
[Telomeres and telomerase]
Ugeskrift for Læger.
2010 Okt4;172(40):2745-8.

Caliebe A, Kleindorp R, Blanché H, Christiansen L, Puca AA, Rea IM, Slagboom E, Flachsbart F, Christensen K, Rimbach G, Schreiber S, Nebel A.
No or only population-specific effect of PON1 on human longevity: A comprehensive meta-analysis.
Ageing Res Rev. 2010 Jul;9(3):238-44. Pubmed abstract

Cournil A, Jeune B, Skytthe A, Gampe J, Passarino G, Robine JM.
Handgrip Strength: Indications of Paternal Inheritance in Three European Regions.
J Gerontol. 2010 Oct;65(10):1101-6. Pubmed abstract

Dato S, Krabbe KS, Thinggaard M, Pedersen BK, Christensen K, Bruunsgaard H, Christiansen L.
Commonly studied polymorphisms in inflammatory cytokine genes show only minor effects on mortality and related risk factors in nonagenarians.
J Gerontol A Biol Sci Med Sci. 2010 Mar;65(3):225-35. Pubmed abstract

de Souza-Pinto NC, Aamann MD, Kulikowicz T, Stevnsner T, Bohr VA.
Mitochondrial helicases and mitochondrial genome maintenance.
Mech Ageing Dev. 2010 Jul-Aug;131(7-8):503-10. Pubmed abstract

Ekmann A, Vass M, Avlund K.
Preventive home visits to older home-dwelling people in Denmark: Are invitational procedures of importance?
Health Soc Care Community. 2010 Nov;18(6):563-71. Pubmed abstract

Gredilla R, Bohr V, Stevnsner T.
Mitochondrial DNA repair and association with aging - an update.
Exp Gerontol. 2010 Aug;45(7-8):478-88. Pubmed abstract

Gredilla R, Garm C, Holm R, Bohr VA, Stevnsner T.
Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions.
Neurobiol Aging. 2010 Jun;31(6):993-1002. Pubmed abstract

Jacobsen R, Martinussen T, Christiansen L, Jeune B, Andersen-Ranberg K, Vaupel JW, Christensen K.
Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: Two nationwide cohort studies.
Aging Cell 2010 Dec;9(6):1004-9. Pubmed abstract

Jagger C, Christensen K, Murphy M.
Cohort differences in mortality and morbidity.
British Actuarial Journal. 2010 Dec;15(Suppl.):65-71.

Jeune B.
Et langt eller sundt liv?
[A long or healthy life?]
FOA: Fag og Arbejde,
2010 Aug:34-5.

Jeune B, Robine J, Young R, Desjardins B, Skytthe A, Vaupel JW.
Jeanne Calment and her successors. Biographical notes on the longest living humans.
In:Supercentenarians. Maier H, Gampe J, Jeune B, Robine J, Vaupel J (ed.).
Berling-Heidelberg: Springer 2010:285-323. (Demographic Research Monographs). Read online...

Lund R, Nilsson CJ, Avlund K.
Can the higher risk of disability onset among older people who live alone be alleviated by strong social relations? A longitudinal study of non-disabled men and women.
Age Ageing. 2010 May;39(3):319-26. Pubmed abstract

Madsen M, Nybo Andersen AM, Christensen K, Andersen PK, Osler M.
Does educational status impact adult mortality in Denmark? A twin approach.
Am J Epidemiol. 2010 Jul;172(2):225-34. Pubmed abstract

Maier H, Gampe J, Jeune B, Robine J, Vaupel J (ed.).
Supercentenarians.
Berling-Heidelberg: Springer. (Demographic Research Monographs), 2010. Read online...

McGue M, Osler M, Christensen K.
Causal inference and observational ageing research: The utility of twins.
Perspec Psychol Sci. 2010 Oct;5(5):546-56. Pubmed abstract

Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB Sr, Fitzpatrick AL, Franceschini N, Glazer NL, Gudnason V, Hofman A, Kaplan R, Karasik D, Kelly-Hayes M, Kiel DP, Launer LJ, Marciante KD, Massaro JM, Miljkovic I, Nalls MA, Hernandez D, Psaty BM, Rivadeneira F, Rotter J, Seshadri S, Smith AV, Taylor KD, Tiemeier H, Uh HW, Uitterlinden AG, Vaupel JW, Walston J, Westendorp RG, Harris TB, Lumley T, van Duijn CM, Murabito JM.
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.
J Gerontol A Biol Sci Med Sci. 2010 May;65(5):478-87. Pubmed abstract

Nilsson CJ, Avlund K, Lund R.
Mobility disability in midlife: A longitudinal study of the role of anticipated instrumental support and social class.
Arch Gerontol Geriatr. 2010 Sep-Oct;51(2):152-8. Pubmed abstract 

Nilsson C, Avlund K, Lund R.
Social inequality in onset of disability among older Danes. The mediation of effects of social relations.
J Aging Health. 2010 Jun;22(4):522-41. Pubmed abstract

Oksuzyan A, Brønnum-Hansen H, Jeune B.
Gender gap in health expectancy.
Eur J Ageing. 2010; 7(4):213-8.

Oksuzyan A, Crimmins E, Saito Y, O'Rand A, Vaupel JW, Christensen K.
Cross-national comparison of sex differences in health and mortality in Denmark, Japan and the US.
Eur J Epidemiol. 2010 Jul;25(7):471-80. Pubmed abstract

Oksuzyan A, Maier H, McGue M, Vaupel JW, Christensen K.
Sex Differences in the level and rate of change of physical function and grip strength in the Danish 1905-Cohort study.
J Aging Health. 2010 Aug;22(5):589-610. Pubmed abstract

Olsen J, Christensen K, Murray J, Ekbom A.
An introduction to epidemiology for health professionals.
Ahrens W, Pigeot I (series editors).
Springer Series on Epidemiology and Health, Springer, 2010.

Osler M.
Sundhed følger social position.
[Health is a consequence of social position]
Nyt om Forebyggelse.
Region Hovedstaden. 2010:18(3).

Osler M.
Gammelt studie afslører nutidens ulighed.
[Old study brings present inequality to light]
Nyt om Forebyggelse.
Region Hovedstaden. 2010:18(4-5).

Osler M, Linneberg A.
På sporet af vores helbred.
[On the track of our health]
Nyt om Forebyggelse.
Region Hovedstaden. 2010:19(3).

Osler M.
Delte meninger om lav fødselsvægt.
[Opinions on low birth weight]
Nyt om Forebyggelse.
Region Hovedstaden. 2010:19(10).

Singh R, Kølvraa S, Bross PG, Christensen K, Bathum L, Gregersen N, Tan Q, Rattan S.
Anti-Inflammatory Heat Shock Protein 70 Genes are Positively Associated with Human Survival.
Curr Pharm Des. 2010; 16; 7: 796-801. Pubmed abstract

Skytthe A, Hervonen A, Ruisdal C, Jeune B.
Supercentenarians in the Nordic Countries.
In:Supercentenarians. Maier H, Gampe J, Jeune B, Robine J, Vaupel J (ed.).
Berling-Heidelberg: Springer 2010, s. 285-323. (Demographic Research Monographs). Læs online...

Sørensen M, Dato S, Christensen K, McGue M, Stevnsner T, Bohr VA, Christiansen L.
Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data.
Aging Cell. 2010 Dec;9(6):1010-7. Pubmed abstract

Tan Q, Ohm Kyvik K, Kruse TA, Christensen K.
Dissecting complex phenotypes using the genomics of twins.
Funct Integr Genomics. 2010 Aug;10(3):321-7. Pubmed abstract

Tan Q, Zhao JH, Li S, Kruse TA, Christensen K.
Power assessment for genetic association study of human longevity using offspring of long-lived subjects.
Eur J Epidemiol. 2010;25(7):501-6. Pubmed abstract

Thinggaard M, Jacobsen R, Jeune B, Martinussen T, Christensen K.
Is the relationship between BMI and mortality increasingly U-shaped with advancing age? A 10-year follow-up of persons aged 70-95 years.
J Gerontol A Biol Sci Med Sci. 2010 May;65(5):526-31. Pubmed abstract

Vaupel JW.
Biodemography of human ageing.
Nature. 2010 Mar 25;464(7288):536-42. Review.

Yashin AI, Arbeev KG, Kulminski A, Borecki I, Christensen K, Barmada M, Hadley E,Rossi W, Lee JH, Cheng R, Elo IT.
“Predicting” parental longevity from offspring endophenotypes: Data from the Long Life Family Study (LLFS).
Mech Ageing Dev. 2010 Mar;131(3):215-22. Pubmed abstract

Aamann MD, Sorensen MM, Hvitby C, Bergquist B, Muftuoglu M, Tian J, de Souza-Pinto NC, Schiebye-Knudsen M, Wilson III DM, Stevnsner T, Bohr VA.
Cockayne Syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane.
FASEB J. 2010 Jul;24(7):2334-46. Pubmed abstract

2009:

Andersen-Ranberg K.
Aldringsfysiologi.
[Ageing physiology]
In: Livet som ældre i det moderne samfund. Glasdam S, Esbensen BA (ed.).
Gerontologi. Dansk Sygeplejeråd. Nyt Nordisk Forlag Arnold Busck. 2009: 123-147.

Andersen-Ranberg K, Petersen I, Frederiksen H, Mackenbach J, Christensen K.
Cross-national differences in grip strength among 50+ year old Europeans: Results from the SHARE study.
Eur J Ageing. 2009; 6; 3: 227-236.

Avlund K.
Betydningen af god funktionsevne og godt netværk.
[The impontance of ability and social networks.]
In: (Ed.) Riis P, Gerlach J. Ældre og psykisk sygdom – forebyggelse, behandling og omsorg.
Ældreforum og Psykiatrifondens Forlag 2009: 197-210.
[Elderly and mental illness - prevention, treatment, and care.]

Avlund K, Bruunsgaard H, Christensen U, Fiehn NE, Hansen ÅM, Holm-Pedersen PH, Jepsen E, Molbo D, Mortensen EL, Lund R.
CAMB – Copenhagen Aging and Midlife Biobank. Perspektiver for fremtidig forskning.
[CAMB - Copenhagen Aging and Midlife Biobank. Perpectives on future research.]
Miljø og Sundhed.
2009; 15: suppl. nr 1: 81-88.

Avlund K, Vass M.
Preventive home visits to the elderly and education of home visitors.
In: Söderback (ed). International Handbook of Occupational Therapy Interventions.
Springer Science. 2009, 473-80.

Avlund K, Vass M.
Preventive Interventions: Overview.
In: Söderback I (ed). International Handbook of Occupational Therapy Interventions.
Springer Science. 2009: 461-4.

Avlund K, Schultz-Larsen K, Krustrup U, Christiansen N, Holm-Pedersen P.
Effect of inflammation in the periodontium in early old age on mortality at 21-year follow-up.
J Am Geriatric Soc. 2009; 57: 1206-12. Pubmed abstract

Avlund K.
Tidlige aldringstegn og betydningen af livsforløbet for aldringsprocessen.
[Early signs of ageing and the importance of lifecourse factors for the ageing process]
Ugeskrift for Læger.
2009 Aug 24;171(35):2481-4.

Barbieri M, Paolisso G, Kimura M, Gardner JP, Boccardi V, Papa M, Hjelmborg JvB, Christensen K, Brimacombe M, Nawrot TS, Staessen JA, Pollak MN, Aviv A.
Higher circulating levels of IGF-1 are associated with longer leukocyte telomere length in healthy subjects.
Mech Ageing Dev. 2009 November - December;130(11-12):771-776. Pubmed abstract

van den Berg GJ, Doblhammer G, Christensen K.
Exogenous determinants of early-life conditions, and mortality later in life.
Soc Sci Med. 2009 May;68(9):1591-8. Pubmed abstract

Broennum-Hansen H, Petersen I, Jeune B, Christensen K.
Lifetime according to health status among the oldest olds in Denmark.
Age Ageing. 2009 Jan;38(1):47-51. Pubmed abstract

Christensen K.
Hvorfor ældes vi så forskelligt?
[Why do we age so differently?]
In: Livet som ældre i det moderne samfund. Glasdam S, Esbensen BA (ed.).
Gerontologi. Dansk Sygeplejeråd. Nyt Nordisk Forlag Arnold Busck. 2009: 150-161.

Christensen K.
Aldring.
[Ageing]
In: Medicinsk Kompendium. Schaffalitzky de Muckadell OB, Haunsø S, Vilstrup H (ed.).
Nyt Nordisk Forlag Arnold Busck Vol. 1, 17. udgave, 2009.

Christensen K, Doblhammer G, Rau R, Vaupel JW.
Ageing populations: the challenges ahead.
Lancet. 2009 Oct 3;374(9696):1196-208. Pubmed abstract

Christensen K, Juel K.
Helbred og dødelighed hos mænd og kvinder - et paradoks.
[Health and mortality among men and women - a paradox]
Gerontologi.
2009; 25; 3: 14-17.

Christensen K, Thinggaard M, McGue M, Rexbye H, Hjelmborg JvB, Aviv A, Gunn D, van der Ouderaa F, Vaupel JW.
Perceived age as clinically useful biomarker of ageing: cohort study.
BMJ. 2009 Dec; 339,b5232:1-6. Pubmed abstract

Christiansen L, Tan Q, Kruse TA, McGue M, Christensen K.
Candidate region linkage analysis in twins discordant or concordant for depression symptomatology.
Am J Med Genet B Neuropsychiatr Genet. 2009 Jun;150B(4):581-4. Pubmed abstract

de Souza-Pinto NC, Mason PA, Hashiguchi K, Weissman L, Tian J, Guay D, Lebel M, Stevnsner T, Rasmussen LJ, Bohr VA.
Novel DNA mismatch repair activity involving YB-1 in human mitochondria.
DNA Repair. 2009; 8:704-719. Pubmed abstract

Engberg H, Oksuzyan A, Jeune B, Vaupel JW, Christensen K.
Centenarians – a useful model for healthy aging? A 29-year follow-up of hospitalizations among 40 000 Danes born in 1905.
Aging Cell. 2009;8: 270–276. Pubmed abstract

Fraser A, Thinggaard M, Christensen K, Lawlor DA.
Alanine aminotransferase, gamma-glutamyltransferase (GGT) and all-cause mortality: Results from a population-based Danish twins study.
Liver Int. 2009 Nov;29(10):1494-9. Pubmed abstract

Gunn DA, Rexbye H, Griffiths CE, Murray PG, Fereday A, Catt SD, Tomlin CC, Strongitharm BH, Perrett DI, Catt M, Mayes AE, Messenger AG, Green MR, van der Ouderaa F, Vaupel JW, Christensen K.
Why some women look young for their age.
PLoS One. 2009 Dec 1;4(12):e8021. Pubmed abstract

Jeune B.
En ny generation af meget gamle - det lange liv
[A new generation of very olds - longevity]
In: Livet som ældre i det moderne samfund. Glasdam S, Esbensen BA (ed.).
Gerontologi. Dansk Sygeplejeråd. Nyt Nordisk Forlag Arnold Busck. 2009: 163-176.

Johnson W, Deary IJ, McGue M, Christensen K.
Genetic and environmental transactions linking cognitive ability, physical fitness, and education in late life.
Psychol Aging. 2009; 24; 1: 48-62. Pubmed abstract

Johnson W, Deary IJ, McGue M, Christensen K.
Genetic and environmental links between cognitive and physical functions in old age.
J Gerontol B Psychol Sci Soc Sci. 2009 Jan;64(1):65-72. Pubmed abstract

Krabbe KS, Mortensen EL, Avlund K, Pilegaard H, Christiansen L, Pedersen AN, Schroll M, Jørgensen T, Pedersen BK, Bruunsgaard H.
Genetic priming of a proinflammatory profile predicts low IQ in octogenarians.
Neurobiol Aging. 2009 May;30(5):769-81. Pubmed abstract

Krabbe KS, Mortensen EL, Avlund K, Pedersen AN, Pedersen BK, Jørgensen T, Bruunsgaard H.
Brain-derived neurotrophic factor predicts mortality risk in older women.
J Am Geriatr Soc. 2009 Aug;57(8):1447-52. Pubmed abstract

Kulminski AM, Arbeev KG, Culminskaya IV, Ukraintseva SV, Christensen K, Yashin A.
Health-related phenotypes and longevity in Danish twins.
J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):1-8. Pubmed abstract

Maddukuri L, Speina E, Christiansen M, Dudzińska D, Zaim J, Obtułowicz T, Kabaczyk S, Komisarski M, Bukowy Z, Szczegielniak J, Wójcik A, Kuśmierek JT, Stevnsner T, Bohr VA, Tudek B.
Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal.
Mutat Res. 2009 Jun;666(1-2):23-31. Pubmed abstract

Muftuoglu M, de Souza-Pinto NC, Dogan A, Aamann M, Stevnsner T, Rybanska I, Kirkali G, Dizdaroglu M, Bohr VA.
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase.
J Biol Chem. 2009 Apr;284(14):9270-9. Pubmed abstract

Oksuzyan A, Petersen I, Stovring H, Bingley P, Vaupel JW, Christensen K.
The male-female health-survival paradox: A survey and register study of the impact of sex-specific selection and information bias.
Ann Epidemiol. 2009 Jul;19(7):504-11. Pubmed abstract

Osler M, Madsen M, Andersen AMN, Avlund K, McGue M, Jeune B, Christensen K.
Do childhood and adult socioeconomic circumstances influence health and physical function in middle-age?
Soc Sci Med. 2009 Apr;68(8):1425-31. Pubmed abstract

Sebastiani P, Hadley EC, Province M, Christensen K, Rossi W, Perls TT, Ash AS.
A family longevity selection score: ranking sibships by their longevity, size, and availability for study.
Am J Epidemiol. 2009 Dec 15;170(12):1555-62. Pubmed abstract

Soerensen M, Christensen K, Stevnsner T, Christiansen L.
The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old.
Mech Ageing Dev. 2009 May;130(5):308–14. Pubmed abstract

Soerensen M, Gredilla R, Müller-Ohldach M, Werner A, Bohr VA, Osiewacz HD, Stevnsner T.
A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: Decrease in mitochondrial DNA repair activity during ageing.
Mech Ageing Dev. 2009 Aug;130(8):487-96. Pubmed abstract

Vass M, Avlund K, Siersma V, Hendriksen C.
A feasible model for prevention of functional decline in older home-dwelling people – the GP role. A municipality-randomised intervention trial.
Fam Pract. 2009; 26:56-64. Pubmed abstract

Aamann MD, Stevnsner T.
Cockayne Syndrome Group B Protein and Chromatin Structure.
In: Ahmad, S. I.: Molecular Mechanisms of Cockayne Syndrome, Landes Bioscience, 2009: Kapitel 3.

2008:

Bukowy Z, Harrigan JA, Ramsden DA, Bohr VA, Stevnsner T.
WRN exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either strand.
Nucl Acids Res. 2008 Sep;36(15):4975-87. Pubmed abstract

Bukowy Z, Harrigan JA, Ramsden DA, Bohr VA, Stevnsner T.
WRN exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either strand.
Nucl Acids Res. 2008 Sep;36(15):4975-87. Pubmed abstract

Christensen K.
Some challenges and possibilities for aging research.
Demograph Res. 2008 Sep;19(43):1575-86. Læs online

Christensen K, McGue M, Petersen I, Jeune B, Vaupel JW.
Exceptional longevity does not result in excessive levels of disability.
Proc Nat Acad Sci U S A. 2008 Sep;105(36):13274-9. Pubmed abstract

Engberg H, Christensen K, Andersen-Ranberg K, Vaupel JW, Jeune B.
Improving Activities of Daily Living in Danish Centenarians - But Only in Women: A Comparative Study of Two Birth Cohorts Born in 1895 and 1905.
J Gerontol A Biol Sci Med Sci. 2008 Nov;63(11):1186-92. Pubmed abstract

Engberg H, Christensen K, Andersen-Ranberg K, Jeune B.
Cohort changes in cognitive function among Danish centenarians. A comparative study of 2 birth cohorts born in 1895 and 1905.
Dement Geriatr Cogn Disord. 2008;26(2):153-60. Pubmed abstract

Gunn DA, Murray PG, Tomlin CC, Rexbye H, Christensen K, Mayes AE.
Perceived age as a biomarker of ageing: A clinical methodology.
Biogerontology. 2008 Oct;9(5):357-64. Pubmed abstract

Jacobsen R, Oksuzyan A, Engberg H, Jeune B, Vaupel JW, Christensen K.
Sex differential in mortality trends of old-aged Danes: A nation wide study of age, period and cohort effects.
Eur J Epidemiol. 2008;23(11):723-30. Pubmed abstract

Kimura M, Hjelmborg JvB, Gardner JP, Bathum L, Brimacombe M, Lu X, Christiansen L, Vaupel JW, Aviv A, Christensen K.
Telomere length and mortality: a study of leukocytes in elderly Danish twins.
Am J Epidemiol. 2008;167:799-806. Pubmed abstract

Oksuzyan A, Juel K, Vaupel JW, Christensen K.
Males: Good health and high mortality. Sex differences in health and ageing (Review).
Aging Clin Exp Res. 2008 Apr;20(2):91-102. Pubmed abstract

Osler M, McGue M, Lund R, Christensen K.
Marital status and twins’ health and behaviour: An analysis of middle-aged Danish twins.
Psychosomatic Med. 2008;70:482-7. Pubmed abstract

Sander M, Avlund K, Lauritzen M, Gottlieb T, Stevnsner T, Wewer U, Bohr VA.
Aging - from molecules to populations.
Mech Aging Dev. 2008 Oct;129(10):614-23. Pubmed abstract

Stevnsner T, Muftuoglu M, Aamann MD, Bohr VA.
The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging (review).
Mech Aging Dev. 2008 Jul-Aug,129(7-8),441-8. Pubmed abstract

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