Research publications

Age-dependent DNA methylation patterns on the Y chromosome in elderly males.
Lund JB, Li S, Christensen K, Mengel-From J, Soerensen M, Marioni RE, Starr J, Pattie A, Deary IJ, Baumbach J, Tan Q.
Aging Cell. Pubmed abstract [Epub ahead of print]

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies.
Mengel-From J, Svane AM, Pertoldi C, Kristensen TN, Loeschcke V, Skytthe A, Christensen K, Lindahl-Jacobsen R, Hjelmborg J, Christiansen L.
J Gerontol A Biol Sci Med Sci. 2019. Pubmed abstract [Epub ahead of print]

Declining cancer incidence at the oldest ages: Hallmark of aging or lower diagnostic activity?

Pedersen JK, Rosholm JU, Ewertz M, Engholm G, Lindahl-Jacobsen R, Christensen K.

J Geriatr Oncol. 2019. Pubmed abstract [Epub ahead of print]

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.
Skytthe A, Harris JR, Czene K, Mucci L, Adami HO, Christensen K, Hjelmborg J, Holm NV, Nilsen TS, Kaprio J, Pukkala E.
Twin Res Hum Genet. 2019. Pubmed abstract [Epub ahead of print]

Parallel progress in perceived age and life expectancy.
Steiner UK, Larsen LA, Christensen K.
J Gerontol A Biol Sci Med Sci. 2019. Pubmed abstract [Epub ahead of print]

Optimizing the Feasibility and Scalability of a Geriatric Surgery Quality Improvement Initiative.

Hornor MA, Tang VL, Berian J, Robinson TN, Coleman J, Katlic MR, Rosenthal RA, Christensen K, Baker T, Finlayson E, Lagoo-Deenadaayalan SA, Ko CY, Russell MM.

J Am Geriatr Soc. 2019 May; 67(5):1074-1078. Pubmed abstract

Health care professionals' attitudes towards deprescribing in older patients with limited life expectancy: a systematic review.

Lundby C, Graabaek T, Ryg J, Søndergaard J, Pottegård A, Nielsen D.

Br J Clin Pharmacol. 2019 May;85(5):868-892. Pubmed abstract


A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Marron MM, Miljkovic I, Boudreau RM, Christensen K, Feitosa MF, Lee JH, Sebastiani P, Thyagarajan B, Wojczynski MK, Zmuda JM, Newman AB; Long Life Family Study.

Metabolism. 2019 May;94:28-38. Pubmed abstract

The Effect of Economic Assets on Mortality in Patients with Dementia: A Population-Based Cohort Study.
Bebe A, Siersma V, Kragstrup J, Nielsen ABS, Møller A, Søndergaard J, Rós Nicolaisdóttir D, Waldorff FB.
J Alzheimers Dis. 2019 Apr;67(4):1245-1253. Pubmed abstract


A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Medford A, Christensen K, Skytthe A, Vaupel JW.

Demography. 2019 Apr;56(2):665-677. Pubmed abstract


Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts.

Jylhävä J, Hjelmborg J, Soerensen M, Munoz E, Tan Q, Kuja-Halkola R, Mengel-From J, Christensen K, Christiansen L, Hägg S, Pedersen NL, Reynolds CA.

EBioMedicine. 2019 Feb;40:710-716. Pubmed abstract


Polyfarmaci og almen praksis.

Andersen JS, Bro F, Søndergaard J, Thomsen JL.

Ugeskr Laeger. 2019 Jan 21;181(4). Ugeskriftet


Intergenerational relations and social mobility: Social inequality in physical function in old age.

Jørgensen TSH, Nilsson CJ, Lund R, Siersma V, Fors S.

Arch Gerontol Geriatr. 2019 Jan;80:58-64. Pubmed abstract


Mobility limitation as determinant of primary care use and ambulatory care sensitive conditions.
Jørgensen TSH, Siersma V, Lund R, Nilsson CJ.
Eur Geriatr Med. 2019 Feb;10(1):53-60.


Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Kraja AT, Christensen K et al.

Am J Hum Genet. 2019 Jan;104(1):112-138. Pubmed abstract


Independent associations of TOMM40 and APOE variants with body mass index.
Kulminski AM, Loika Y, Culminskaya I, Huang J, Arbeev KG, Bagley O, Feitosa MF, Zmuda JM, Christensen K, Yashin AI; Long Life Family Study Research Group.
Aging Cell. 2019 Feb;18(1):e12869. Pubmed abstract


Digital Recruitment and Acceptance of a Stepwise Model to Prevent Chronic Disease in the Danish Primary Care Sector: Cross-Sectional Study.

Larsen LB, Sondergaard J, Thomsen JL, Halling A, Sønderlund AL, Christensen JR, Thilsing T.

J Med Internet Res. 2019 Jan 21;21(1):e11658. Pubmed abstract


DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns.

Lund JB, Li S, Baumbach J, Svane AM, Hjelmborg J, Christiansen L, Christensen K, Redmond P, Marioni RE, Deary IJ, Tan Q.

Clin Epigenetics. 2019 Feb;11(1):23. Pubmed abstract


APOE Alleles and Extreme Human Longevity.

Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, Perls TT.

J Gerontol A Biol Sci Med Sci. 2019 Jan;74(1):44-51. Pubmed abstract


Tools for Deprescribing in Frail Older Persons and Those with Limited Life Expectancy: A Systematic Review.

Thompson W, Lundby C, Graabaek T, Nielsen DS, Ryg J, Søndergaard J, Pottegård A.

J Am Geriatr Soc. 2019 Jan;67(1):172-180. Pubmed abstract


Selected publications:

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