Functional Genomics & Metabolism Research Unit

The Functional Genomics & Metabolism Research Unit is composed of the
Mandrup, Grøntved, Ravnskjær, Natarajan, and Kornfeld research groups.
Mandrup is Director of and Grøntved and Ravnskjær are partners in
Center for Functional Genomics and Tissue Plasticity (ATLAS).



Isabel Forss has succesfully defended her PhD 

December 5, 2017 Isabel Forss defended her PhD thesis by giving the talk "Transcriptional regulation of lineage determination and differentiation of adipocytes". Isabel has been an inspiring part of the Mandrup Group since she started in the group as bachelor student back in 2011. We wish you all the best in your future endeavours. 



Employees of the week in November and December

At our weekly group meetings, group members who have done an extraordinary effort to the lab, can be appointed as employees of the week. During November and December the people below was selected for their hard and appreciated work - thank you!

Week 48 - Majken and Tenna for arranging a very nice Christmas-hygge evening

Week 46 - Lasse and Marjoleine for saving one of our beloved -80 freezers

Week 45 - Tenna and Maibrith for cleaning the ventilation system in our cold room



Sapere Aude - Starting Grant

Lars Grøntved, PI in ATLAS, Center for Functional Genomics and Tissue Plasticity, and Assistant Professor in the Functional Genomics and Metabolism Research Unit, receives the prestigious Sapere Aude - Starting Grant.

On November 22, 2017 Independent Research Fund Denmark announced that Lars Grøntved was one of the 29 out of 388 successful applicants.
Read the press release
Read about Lars Grøntved’s research project







Professor Susanne Mandrup now holds an EMBO membership




EMBO is an organization of more than 1700 leading researchers that promotes excellence in the life sciences.
In June 2017, Professor Susanne Mandrup joined the organization, and one of her tasks is to participate in the evaluation of applications for EMBO funding.

Read the EMBO press release

Read the presentation of Professor Mandrup on the EMBO homepage


ATLAS opening on the Danish National Research Foundation homepage

Read about the ATLAS opening on the Danish National Research Foundation homepage


3 guest speakers honored us by presenting their research at the scientific symposium in the afternoon:

  • Kirsi Virtanen, Adjunct Profressor, Turku PET Centre, Finland
  • Matthias Mann, Director, Max-Planck Institute of Biochemistry, Munich, Germany
  • Madan Babu, Programme Leader, MRC Cambridge, United Kingdom


Open postdoc and PhD positions

We have currently 3 Postdoc positions and 4 PhD positions open

Read the full job description here

Application deadline for all positions is 28th of November, 2017


January 1, 2018

We are happy to announce that Jan-Wilhelm Kornfeld is appointed as professor at BMB, SDU starting January 1, 2018. His professorship is funded by the Danish Diabetes Academy supported by a grant from the Novo Nordisk Foundation. Jan-Wilhelm Kornfeld will join the Functional Genomics and Metabolism Resarch Unit.







Read more

November 6, 2017

The official opening of ATLAS, our new Center of Excellence, founded by the Danish National Research Foundation, will take place on November 6, 2017.

In the morning there will be official speeches and musical entertainment and in the afternoon there will be a scientific symposium. Please see the program for the day: ATLAS Opening and Symposium







1 September 2017

Our new Center of  Excellence, ATLAS, has per September 1, 2017, employed Ellen Kathrine Arve as Center Administrator.
Welcome on the team, Ellen Kathrine!



16 June 2017

From June 6-7 most members of our Functional Genomics & Metabolism Research Unit went on a 2-days retreat at SDU Research Station in Svanninge Bjerge, Faaborg, to host our annual strategy meeting. This year we had invited Prof. Ormond MacDougald from University of Michigan and Dr. Peter Tontonoz from University of California to participate in our meeting. 

Click here to see pictures from our retreat.

8 May 2017




Professor Susanne Mandrup has received 65 million DKK from the Danish National Research Foundation to establish a new Center of Excellence – “Center for Functional Genomics and Tissue Plasticity” – ATLAS

In this Center of Excellence, we will investigate how specific cell types in the liver and fat tissues change their properties during development of obesity and fatty liver disease. We will use a combination of advanced functional genomics technologies, transgenic mouse models, proteomics and bioinformatics to uncover the fascinating plasticity of cells. 
Our vision is to obtain fundamentally new insight into plasticity of cells in the tissue context and to translate this knowledge into the clinical setting to improve our understanding, diagnosis and treatment of obesity-related diseases.   
The official announcement of the granting of ATLAS was celebrated at the Department of Biochemistry and Molecular Biology April 19, 2017, where both the Head of Department Peder Thusgaard Ruhoff and the Dean of Faculty of Science Martin Zachariasen used the opportunity to congratulate Susanne and the entire ATLAS team with the outstanding achievement and thank them of getting a Center of Excellence to SDU. 

The good news has also been announced on the SDU homepage - 
New Center of Excellence 

The new Center of Excellence consists of researchers from both the Faculty of Science, the Faculty of Health Science and Odense University Hospital:

Research leaders associated with ATLAS:

Department of Biochemistry and Molecular Biology, Faculty of Science: 
Prof. Susanne Mandrup, Assoc. Prof. Lars Grøntved, Asst. Professor Kim Ravnskjær, Prof. Blagoy Blagoev  

Department of Mathematics and Computer Science, Faculty of Science:
Assoc. Prof. Jan Baumbach 

Department of Molecular Medicine, Faculty of Health Science:
Prof. Søren Kragh Moestrup, Assoc. Prof. Jonas Graversen 

Department of Clinical research, Medical Gastroenterology, Odense University Hospital:
Prof. and Physician Aleksander Krag


25 March 2017

Danish Diabetes Academy Visiting Professor James Granneman from Molecular Medicine and Genetics and  Internal Medicine, Wayne State University School of Medicine will arrive and stay until the end of April. Welcome!

10 March 2017

Sofie Traynor successfully defended her  PhD thesis "Function and Genomic Interactome of Early Adipogenic Transcription Factor Hotspots "

24 February 2017

Kim Ravnskjær received 200.000 DKK from the Augustinus Foundation for the project: “Identification of fibrose-associated membrane receptors in the liver and investigation of their potential in treatment of chronic liver disease”.

1 February 2017

Sofie Marchsteiner Bendixen is now a PhD student with Kim Ravnskjær as her supervisor.

1 February 2017

Stine Marie Præstholm is now a PhD student with Lars Grøntved as her supervisor.

17 January 2017

Our manuscript “Genome-wide insights into development and function of thermogenic adipocytes” is now out in Trends in Endocrinology and Metabolism. Please click on the cover picture below to read more.











15 January 2017

Lasse Markussen is now a PhD student in the Mandrup Group.

4 January 2017

Results of the annual comptetition of the group's cleanest/ tidiest office and the most welcoming office :

December 2016

 Mette Larsen is now a PhD student in the Mandrup Group.

28 November 2016

We had our yearly Christmas-hygge day in the Group



11 November 2016

 James Granneman, Professor of Molecular Medicine and Genetics and of Internal Medicine, Wayne State University School of Medicine  is appointed Danish Diabetes Academy Visiting Professor in the group in 2017

7 November 2016

Our manuscript “Genome-wide insights into development and function of thermogenic adipocytes” was accepted by Trends in Endocrinology and Metabolism

3 November 2016

Our manuscript "The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation" has been accepted by Nucleic Acids Research

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