Torben Barrington

Title
Professor, MD

Department and Faculty
Centre for Immunotherapy of Haematological Cancer Odense, CITCO, Clinical Department, Faculty of Health Sciences and Odense University Hospital

Funding
Kræftens Bekæmpelse, Lundbeckfonden, A. P. Møller fonden, Bloddonorerne i Danmarks forskningsfond

Research vision
To develop improved CAR T cellular immunotherapy of lymphoid cancers

Three key publications
A pleiotropic variant in DNAJB4 is associated with multiple myeloma risk
Dicanio M, Giaccherini M, Clay-Gilmour A, Macauda A, Sainz J, Machiela MJ, Rybicka-Ramos M, Norman AD, Tyczyńska A, Chanock SJ, Barington T, Kumar SK, Bhatti P, Cozen W, Brown EE, Suska A, Haastrup EK, Orlowski RZ, Dudziński M, Garcia-Sanz R, Kruszewski M, Martinez-Lopez J, Beider K, Iskierka-Jazdzewska E, Pelosini M, Berndt SI, Raźny M, Jamroziak K, Rajkumar SV, Jurczyszyn A, Vangsted AJ, Collado PG, Vogel U, Hofmann JN, Petrini M, Butrym A, Slager SL, Ziv E, Subocz E, Giles GG, Andersen NF, Mazur G, Watek M, Lesueur F, Hildebrandt MAT, Zawirska D, Ebbesen LH, Marques H, Gemignani F, Dumontet C, Várkonyi J, Buda G, Nagler A, Druzd-Sitek A, Wu X, Kadar K, Camp NJ, Grzasko N, Waller RG, Vachon C, Canzian F, Campa D.
Int J Cancer, 2022, Sep 8.
doi: 10.1002/ijc.34278.

Emerging Approaches for Regulation and Control of CAR T Cells: A Mini Review
Brandt LJB, Barnkob MB, Michaels YS, Heiselberg J, Barington T.
Front Immunol. 2020 Feb 26;11:326.
doi: 10.3389/fimmu.2020.00326.

Chimeric antigen receptor T cells targeting CD79b with or without co-targeting of CD19 show preclinical efficacy in lymphoma
Ormhøj M, Scarfó I, Cabral M, Bailey S, Lorrey S, Bouffard A, Castano A, Larson R, Riley L, Schmidts A, Choi B, Andersen R, Cédile O, Nyvold C, Haaber J, Gjerstorff M, Ditzel H, Weinstock D, Barington T, Frigault M, and Maus M.
Clin. Cancer Res. 2019 Dec 1;25(23):7046-7057.
doi: 10.1158/1078-0432.CCR-19-1337