Haematology-Pathology Research Laboratory (HPRL)
Charlotte Nyvold (haematology), Michael Boe Møller (haematopathology)
HPRL is a close collaboration between the departments of haematology and pathology. The lab has students and researchers of all levels, primarily from the Faculties of Health Sciences and Science.
Introduction to research area
HPRL primarily researches haematological diseases such as lymphoma, myeloma and leukaemia. The lab has a molecular focus, but the type of projects in HPRL span the whole range from basic research via translational research to applied research and clinical trials. We are in collaboration with numerous national and international research groups.
The aim of HPRL is to add to our knowledge of the haematological diseases, and to educate researchers in the process. We are very focused on being a bridge between the bench and the bedside.
We have a diverse array of projects in the lab, such as:
Genetic characterisation of molecular progression of haematological cancer
Novel genetic markers for minimal residual disease detection in patients with leukaemia, lymphoma and myeloma
Molecular profiling of chronic lymphocytic leukaemia
Molecular and prognostic characterisation of aggressive B-cell lymphoma
PCR, qPCR, next-generation sequencing, multicolour flow cytometry immunophenotyping, fluorescence-activated cell sorting, immunohistochemistry and many others.