2015

21. Miglietta, Giulia; Cogoi, Susanna; Pedersen, Erik B.; Xodo, Luigi E. GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1. Scientific Reports (2015), 5, 18097. [Abstract]

 

20. Santos, Rita S.; Dakwar, George R.; Xiong, Ranhua; Forier, Katrien; Remaut, Katrien; Stremersch, Stephan; Guimaraes, Nuno; Fontenete, Silvia; Wengel, Jesper; Leite, Marina;  Figueiredo, Céu; De Smedt, Stefaan C.; Braeckmans, Kevin; Azevedo, Nuno F. Effect of Native Gastric Mucus on in vivo Hybridization Therapies Directed at Helicobacter pylori. Molecular Therapy-Nucleic Acids (2015), 4(12), e269. [Abstract]

19. Miglietta, Giulia; Gouda, Alaa S.; Cogoi, Susanna; Pedersen, Erik B.; Xodo, Luigi E. Nucleic acid targeted therapy: G4 Oligonucleotides downregulate HRAS in bladder cancer cells through a decoy mechanism. ACS Medicinal Chemistry Letters (2015), 6(12), 1179-1183. [Abstract]

18. Zahran, Magdy A. H.; Osman, Amany M. A.; Wahed, Rania A.; Attia, Magdy; Pedersen, Erik B.; Elnasser, Gamal A.; Turky, Azza Sh. Design, synthesis and antimicrobial evaluation of novel carbendazim dithioate analogs. Research Journal of Pharmaceutical, Biological and Chemical Sciences (2015), 6(4), 1084-1092. [Abstract]

17. Langkjær, Niels; Wengel, Jesper; Pasternak, Anna. Watson-Crick hydrogen bonding of unlocked nucleic acids. Bioorganic and Medicinal Chemistry Letters (2015), 25(22), 5064-5066. [Abstract]

 

16. Opazo, Felipe; Eiden, Laura; Hansen, Line; Rohrbach, Falk; Wengel, Jesper; Kjems, Jørgen; Mayer, Günter. Modular assembly of cell-targeting devices based on an uncommon G-quadruplex aptamer. Molecular Therapy-Nucleic Acids (2015), 4(9), e251 [Abstract

15. Azevedo, Andreia S.; Almeida, Carina; Pereira, Bruno; Madureira, Pedro; Wengel, Jesper; Azevedo, Nuno F. Detection and discrimination of biofilm populations using locked nucleic acid/2'-O-methyl-RNA fluorescence in situ hybridization (LNA/2'OMe-FISH). Biochemical Engineering Journal (2015), 104, 64-73 [Abstract]

 

14. Ostergaard, Michael E.; Kumar, Pawan; Nichols, Josh; Watt, Andrew; Sharma, Pawan K.; Nielsen, Poul; Seth, Punit P. Allele-selective inhibition of mutant Huntingtin with 2-thio- and C5- triazolylphenyl-deoxythymidine-modified antisense oligonucleotides. Nucleic Acid Therapeutics (2015), 25(5), 266-274 [Abstract

13. Hornum, Mick; Kumar, Pawan; Podsiadly, Patricia; Nielsen, Poul. Increasing the stability of DNA:RNA duplexes by introducing stacking phenyl-substituted pyrazole, furan, and triazole moieties in the major groove. Journal of Organic Chemistry (2015), 80(19), 9592-9602 [Abstract]

 

12. Ries, Oliver; Löffler, Philipp M. G.; Vogel, Stefan. Convenient synthesis and application of versatile nucleic acid lipid membrane anchors in the assembly and fusion of liposomes. Organic & Biomolecular Chemistry (2015), 13(37), 9673-9680 [Abstract]

11. Maity, Arindam; Macaubas, Claudia; Mellins, Elizabeth; Astakhova, Kira. Synthesis of phospholipid-protein conjugates as new antigens for autoimmune antibodies. Molecules (2015), 20(6), 10253-10263. [Abstract]

10. Nabo, Lina J.; Madsen, Charlotte S.; Jensen, Knud J.; Kongsted, Jacob; Astakhova, Kira. Ultramild protein-mediated click chemistry creates efficient oligonucleotide probes for targeting and detecting nucleic acids. ChemBioChem (2015), 16(8), 1163-1167. [Abstract]

 

9. Dalager, Michael; Andersen, Nicolai K.; Kumar, Pawan; Nielsen, Poul; Sharma, Pawan K. Double-headed nucleotides introducing thymine nucleobases in the major groove of nucleic acid duplexes. Organic & Biomolecular Chemistry (2015), 13(25), 7040-7049. [Abstract]

8. Veedu, Rakesh Naduvile; Edwards, Stacey; Poongavanam, Vasanthanathan; Kanwar, Jagat; Roy, Kislay; Hillman, Kristine; Prasad, Neerti; Larsen, Rikke; Petersen, Michael; Marusic, Maja; Plavec, Janez, Wengel, Jesper. Targeting VEGF with LNA-Stabilized G-rich Oligonucleotide for Efficient Breast Cancer Inhibition. Chemical Communications (2015), DOI: 10.1039/C5CC02756J [Abstract]

7. Kosbar, Tamer R.; Sofan, Mamdouh A.; Waly, Mohamed A.; Pedersen, Erik B. Anti-parallel triplexes: Synthesis of 8-aza-7-deazaadenine nucleosides with a 3-aminopropynyl side-chain and its corresponding LNA analog. Bioorganic & Medicinal Chemistry (2015), 23(10), 2458-2469. [Abstract

6. Kosbar, Tamer R.; Sofan, Mamdouh A.; Abou-Zeid, Laila; Pedersen, Erik B. Thermal stability of G-rich anti-parallel DNA triplexes upon insertion of LNA and α-L-LNA. Organic & Biomolecular Chemistry (2015), 13(18), 5115-5121. [Abstract

5. Fontenete Silvia; Leite Marina; Ferreira Rui Manuel; Guimaraes Nuno; Madureira Pedro; Figueiredo Ceu; Wengel Jesper; Azevedo Nuno Filipe. Towards fluorescence in vivo hybridization (FIVH) detection of H. pylori in Gastric Mucosa using advanced LNA probes. PLoS ONE (2015) 10(4): e0125494 [Open Access]

4. Elle, Ida C.; Karlsen, Kasper K.; Terp, Mikkel G.; Larsen, Niels; Nielsen, Ronni; Derbyshire, Nicola; Mandrup, Susanne; Ditzel, Henrik J.; Wengel, Jesper. Selection of LNA-containing DNA aptamers against recombinant human CD73. Molecular BioSystems (2015), 11(5), 1260-1270. [Abstract] (2015 Hot articles)

3. Lou, Chenguang; Vester, Birte; Wengel, Jesper. Oligonucleotides containing a piperazino-modified 2’-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance. Chemical Communications (2015), 51(19), 4024-4027. [Abstract]

2. Fontenete Silvia; Barros Joana; Madureira Pedro; Figueiredo Céu; Wengel Jesper; Azevedo Nuno Filipe. Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids. Applied Microbiology and Biotechnology (2015), 99(9), 3961-3969. [Abstract]

1. Fontenete Silvia; Guimaraes Nuno; Wengel Jesper; Azevedo Nuno Filipe. Prediction of melting temperatures in fluorescence in situ hybridization (FISH) procedures using thermodynamic models. Critical reviews in biotechnology (2015), 1-12. [Abstract]