Publications 2020

9. Zeng, Dongdong; Salvatore, Princia; Karlsen, Kasper K.; Zhang, Jingdong; Wengel, Jesper; Ulstrup, Jens. Electrochemical intercalator binding to single- and double-strand DNA- and LNA-based molecules on Au(111)-electrode surfaces. Journal of Electroanalytical Chemistry (2020) 865, 114138. [Abstract]

8.Lou Chenguang; Boesen Josephine Tuborg; Christensen Niels Johan; Sørensen Kasper K; Jensen Knud Jørgen; Thulstrup Peter Waaben; Pedersen Martin Nors; Giralt Ernest; Wengel Jesper. Self-assembly of DNA-peptide supermolecules: Coiled-coil peptide structures templated by D-DNA and L-DNA triplexes exhibit chirality-independent but orientation-dependent stabilizing cooperativity. Chemistry - A European Journal (2020), 26(25), 5676-5684. [Abstract]



7. Abdelrahman, Asmaa; Gouda, Alaa S.; Jørgensen, Per T.; Wengel, Jesper. Novel assemblies based on oligonucleotides containing intercalating nucleic acid monomers. Nucleosides, Nucleotides & Nucleic Acids (2020), 39(1-3), 82-96. [Abstract]


6. Raguraman, Prithi; Wang, Tao; Ma, Lixia; Jørgensen, Per T.; Wengel, Jesper; Veedu, Rakesh N. Alpha-L-locked nucleic acid-modified antisense oligonucleotides induce efficient splice modulation in vitro. International Journal of Molecular Sciences (2020) 21(7), 2434. [Abstract]


5. Christou, Melina; Wengel, Jesper; Sokratous, Kleitos; Kyriacou, Kyriacos; Nikolaou, Georgios; Phylactou, Leonidas A.; Mastroyiannopoulos, Nikolaos P. Systemic evaluation of chimeric LNA/2’O-methyl steric blockers for Myotonic Dystrophy type 1 therapy. Nucleic acid therapeutics. (2019), 30(2), 80-93 [Abstract


4. Löffler, Philipp M. G.; Rabe, Alexander; Vogel, Stefan. Lipid-modified peptide nucleic acids: Synthesis and application to programmable liposome fusion. Book chapter in: Peter E. Nielsen (ed.), Peptide Nucleic Acids: Methods and Protocols. Methods in Molecular Biology (Clifton, N.J.) (2020), 2105, 75-96. [Abstract]


3. Danielsen, Mathias B.; Lou, Chenguang; Lisowiec-Wachnicka, Jolanta; Pasternak, Anna; Jørgensen, Per T.; Wengel, Jesper. Gapmer antisense oligonucleotides containing 2',3'-dideoxy-2'-fluoro-3'-C-hydroxymethyl-β-D-lyxofuranosyl nucleotides display site-Specific RNase H cleavage and induce gene silencing. Chemistry - A European Journal (2020), 26(6), 1368-1379. [Abstract]


2. Löffler, Philipp M. G.; Ries, Oliver; Vogel, Stefan. DNA-Mediated liposome fusion observed by fluorescence spectrometry. Book chapter in: Astakhova K., Bukhari S. (eds) Nucleic Acid Detection and Structural Investigations. Methods in Molecular Biology (Clifton, N.J.) (2020), 2063, 101-118. [Abstract]

1. Duschmale, Jörg; Bleicher, Konrad; Hansen, Henrik Frydenlund; Albaek, Nanna; Møller, Marianne Ravn; Jensen, Klaus; Koch, Troels; Duschmale, Martina; Koller, Erich; Wengel, Jesper; Konrad, Bleicher. In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3' and 5' thiophosphate linkages. Nucleic Acids Research (2020), 48(1), 63-74. [Open Access]