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Publications

A Method for Quantification of Epithelium Colonization Capacity by Pathogenic Bacteria. Pedersen RM, Grønnemose RB, Stærk K, Asferg CA, Andersen TB, Kolmos HJ, Møller-Jensen J, Andersen TE. Front Cell Infect Microbiol. 2018 Feb 1;8:16. doi: 10.3389/fcimb.2018.00016. eCollection 2018. PMID: 29450193

Molecular mechanisms of thioridazine resistance in Staphylococcus aureus. Wassmann CS, Lund LC, Thorsing M, Lauritzen SP, Kolmos HJ, Kallipolitis BH, Klitgaard JK. PLoS One. 2018 Aug 8;13(8):e0201767. doi: 10.1371/journal.pone.0201767. eCollection 2018. PMID: 30089175

Combination of thioridazine and dicloxacillin as a possible treatment strategy of staphylococci. Rasmussen KS, Poulsen MØ, Jacobsen K, Skov MN, Kolmos HJ, Kallipolitis BH, Klitgaard JK. New Microbiol. 2017 Apr;40(2):146-147. Epub 2017 Mar 1. PMID: 28255602

Systemic thioridazine in combination with dicloxacillin against early aortic graft infections caused by Staphylococcus aureus in a porcine model: In vivo results do not reproduce the in vitro synergistic activity. Stenger M, Behr-Rasmussen C, Klein K, Grønnemose RB, Andersen TE, Klitgaard JK, Kolmos HJ, Lind holt JS. PLoS One. 2017 Mar 9;12(3):e0173362. doi: 10.1371/journal.pone.0173362. eCollection 2017. PMID:28278183

Co-release of dicloxacillin and thioridazine from catheter material containing an interpenetrating polymer network for inhibiting device-associated Staphylococcus aureus infection. Stenger M, Klein K, Grønnemose RB, Klitgaard JK, Kolmos HJ, Lindholt JS, Alm M, Thomsen P, Andersen TE. J Control Release. 2016 Nov 10;241:125-134. doi: 10.1016/j.jconrel.2016.09.018. Epub 2016 Sep 20. PMID:27663229

DamX Controls Reversible Cell Morphology Switching in Uropathogenic Escherichia coli. Khandige S, Asferg CA, Rasmussen KJ, Larsen MJ, Overgaard M, Andersen TE, Møller-Jensen J. MBio. 2016 Aug 2;7(4). pii: e00642-16. doi: 10.1128/mBio.00642-16. PubMed PMID: 27486187; PubMed Central PMCID: PMC4981707

Uropathogenic Escherichia coli Express Type 1 Fimbriae Only in Surface Adherent Populations Under Physiological Growth Conditions. Stærk K, Khandige S, Kolmos HJ, Møller-Jensen J, Andersen TE. J Infect Dis. 2016 Feb 1;213(3):386-94. doi: 10.1093/infdis/jiv422. Epub 2015 Aug 19.  PMID:26290608

Draft Genome Sequence of Parabacteroides goldsteinii with Putative Novel Metallo-β-Lactamases Isolated from a Blood Culture from a Human Patient. Krogh TJ, Agergaard CN, Møller-Jensen J, Justesen US. Genome Announc. 2015 Aug 20;3(4). pii:e00937-15. doi: 10.1128/genomeA.00937-15. PubMed PMID: 26294633; PubMed Central
PMCID: PMC4543511

Assessments of Thioridazine as a Helper Compound to Dicloxacillin against Methicillin-Resistant Staphylococcus aureus: In Vivo Trials in a Mouse Peritonitis Model. Stenger M, Hendel K, Bollen P, Licht PB, Kolmos HJ, Klitgaard JK. PLoS One. 2015 Aug 12;10(8):e0135571. doi: 10.1371/journal.pone.0135571. eCollection 2015. PMID:26267376

Quantification of filamentation by uropathogenic Escherichia coli during experimental bladder cell infection by using semi-automated image analysis. Klein K, Palarasah Y, Kolmos HJ, Møller-Jensen J, Andersen TE. J Microbiol Methods. 2015 Feb;109:110-6. doi: 10.1016/j.mimet.2014.12.017. Epub 2014 Dec 26. PMID:25546841

Combination therapy with thioridazine and dicloxacillin combats meticillin-resistant Staphylococcus aureus infection in Caenorhabditis elegans. Poulsen MØ, Schøler L, Nielsen A, Skov MN, Kolmos HJ, Kallipolitis BH, Olsen A, Klitgaard JK. J Med Microbiol. 2014 Sep;63(Pt 9):1174-80. doi: 10.1099/jmm.0.071837-0. Epub 2014 Jun 9. PMID: 24913562

Thioridazine induces major changes in global gene expression and cell wall composition in methicillin-resistant Staphylococcus aureus USA300. Thorsing M, Klitgaard JK, Atilano ML, Skov MN, Kolmos HJ, Filipe SR, Kallipolitis BH. PLoS One. 2013 May 17;8(5):e64518. doi: 10.1371/journal.pone.0064518. Print 2013. PMID:23691239

Thioridazine potentiates the effect of a beta-lactam antibiotic against Staphylococcus aureus independently of mecA expression. Poulsen MØ, Jacobsen K, Thorsing M, Kristensen NR, Clasen J, Lillebæk EM, Skov MN, Kallipolitis BH, Kolmos HJ, Klitgaard JK. Res Microbiol. 2013 Feb-Mar;164(2):181-8. doi: 10.1016/j.resmic.2012.10.007. Epub 2012 Oct 23. PMID:23089256

Escherichia coli uropathogenesis in vitro: invasion, cellular escape, and secondary infection analyzed in a human bladder cell infection model. Andersen TE, Khandige S, Madelung M, Brewer J, Kolmos HJ, Møller-Jensen J. Infect Immun. 2012 May;80(5):1858-67. doi: 10.1128/IAI.06075-11. Epub 2012 Feb 21. PMID:22354025

Thioridazine affects transcription of genes involved in cell wall biosynthesis in methicillin-resistant Staphylococcus aureus. Bonde M, Højland DH, Kolmos HJ, Kallipolitis BH, Klitgaard JK. FEMS Microbiol Lett. 2011 May;318(2):168-76. doi: 10.1111/j.1574-6968.2011.02255.x. Epub 2011 Mar 25. PMID:21375577

Reversal of methicillin resistance in Staphylococcus aureus by thioridazine. Klitgaard JK, Skov MN, Kallipolitis BH, Kolmos HJ. J Antimicrob Chemother. 2008 Dec;62(6):1215-21. doi: 10.1093/jac/dkn417. Epub 2008 Oct 3. PMID:18836185

Last Updated 12.03.2020