During pregnancy, there is a bidirectional exchange of cells between the pregnant woman and her fetus that in some cases lead to the establishment of the presence of small amount of genetically distinct cells in the fetus and/or the mother that may persist many years after pregnancy. This phenomenon is referred to as microchimerism and can be divided into fetal microchimerism (FMc) and maternal microchimerism (MMc). Studies have suggested that MMc and FMc may be involved in pregnancy complications, autoimmune diseases and malignancy, but the exact role is still uncertain. The group works in close collaboration with consultant Henriette Svarre Nielsen and post.doc Astrid Marie Kolte at the Fertility Clinic and Recurrent Pregnancy Loss Unit, Rigshospitalet, and with associate professor Mads Kamper-Jørgensen, Institut for Folkesundhedsvidenskab, Københavns Universitet.
Assistant professor Marianne Antonius Jakobsen
Clinical Immunology, SDU
Klinisk Immunologisk Afdeling
J. B. Winsløws Vej 4, 5000 Odense
Members of the team
Staff at molecular biology group at Department of Clinical Immunology
Mikrokimærisme og reproduktion