Epidemiologi og Biostatistik
Syddansk Universitet (SDU)
J.B. Winsløws Vej 9A. ("Kort")
Sædvanligvis: Lokale 4.39, 3. sal
For information om kommende EB seminarer og for offentliggørelse af EB seminar præsentationer: SEMINAR BOOKING
Program 2018
| 16. Maj | 13:00-15:00 i lokale 25.111 | Kaare Christensen Professor at Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark Applied Twin Research: Aging and Longevity |
| ABSTRACT: Se Ph.d.-kursus: Analysis of Twin Data in Health Research Lokale: 25.111 - J.B. Winsløws Vej 25, Odense SØ - Find vej |
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| 14. Maj | 13:00-14:00 i lokale 25.111 | Jaakko Kaprio Professor at Genetic Epidemiology, Department of Public Health, University of Helsinki, Finland The Future of Twin Studies |
| ABSTRACT: Se Ph.d.-kursus: Analysis of Twin Data in Health Research Lokale: 25.111 - J.B. Winsløws Vej 25, Odense SØ - Find vej |
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| 23. April | 13:00-13:30 i lokale 4.39 | Javier De La Fuente Department of psychiatry, School of Medicine, Universidad Autónoma de Madrid, Spain Longitudinal associations of sensory and cognitive functioning: evidences of the sensory deprivation hypothesis in the English Longitudinal Study of Ageing |
| ABSTRACT: Several cross-sectional and longitudinal studies have shown a link between sensory and cognitive functioning in the elderly. According to the sensory deprivation hypothesis, there is a causal link between impaired perception and cognitive decline, since age-related declines in sensory functioning reduce the quality of sensory stimuli input, which in turn have long-term negative effects on cognitive capacity due to neural atrophy. This study aims at assessing the associations of self-reported visual and hearing difficulties with cognitive functioning in a time-span of eight years in a nationally representative sample of 3508 participants aged 60 and over from the English Longitudinal Study of Ageing. |
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| 12. Marts | 14:00-15:00 i lokale 4.39 | Paolo Caserotti Associate Professor at Department of Sports Science and Clinical Biomechanics, SDU Exercise Referral Schemes enhanced by Self-Management Strategies to battle sedentary behaviour: recruitment challenges, follow-up and needs for new action plans |
| ABSTRACT: The SITLESS project is a large-scale trial that evaluates the long-term effect of a physical activity-based intervention combined with self-management strategies in older adults to decrease sedentary behaviour community-dwelling older adults 65+ and the only multicenter trial ever conducted in the European Union with this purpose.
SITLESS primary aim is to assess the long-term effectiveness (18 month follow-up) of a complex intervention on sedentary behaviour (SB) and physical activity (PA) in 65+ community dwelling older citizens population based on existing exercise referral schemes (ERS) enhanced by self-management-strategies (SMS). Four pilot sites (Denmark, Ireland Germany and Spain) have enrolled over 1400 community-dwelling older adults 65+ using National existing health care pathways. Primary and secondary health outcomes including “health”, quality of life, functional performance, muscle mechanical function psychosocial outcomes are assessed before, after (4 months) and 18 months following the end of the intervention. The study is designed a three-armed pragmatic randomised controlled trial. One of the key of the project is to provide new evidence on how to design, implement and evaluate a complex intervention enhancing exercise-referral schemes (ERS) with self-management strategies (SMS) to decrease sedentary behaviour in community-dwelling older adults, considering end-users’ interests, forming cooperative teams of stakeholders and distributing actions and decisions. We aim to improve physical function and quality of life producing sustainable changes. The background, enrollment and intervention status of the project will be presented. The consortium is seeking for advices to tackle several challenges including recruitment delays and drop-out rate and which scientific consequences this may have on the overall aims. Successful outcomes of the project are potentially important in setting the evidence-based foundations for future European public health policies in this area. Project has been funded under the program Horizon 2020: Number 634270 - (PI: Coll Planas L) 01/05/15- 30/04/19 (4,8 mI €) The trial registration was published nearly one year ago The SITLESS project: exercise referral schemes enhanced by self-management strategies to battle sedentary behaviour in older adults: study protocol for a randomised controlled trial. Giné-Garriga M, Coll-Planas L, Guerra M, Domingo À, Roqué M, Caserotti P, Denkinger M, Rothenbacher D, Tully MA, Kee F, McIntosh E, Martín-Borràs C, Oviedo GR, Jerez-Roig J, Santiago M, Sansano O, Varela G, Skjødt M, Wirth K, Dallmeier D, Klenk J, Wilson JJ, Blackburn NE, Deidda M, Lefebvre G, González D, Salvà A. Trial. 2017 May 18; 18(1):221 Invited by: Kaare Christensen. |
Program 2017
| 19. Dec | 13:00-15:00 i lokale 4.39 | Phillip Hougaard Vice President of Biometrics at Lundbeck and external professor, SDU Personalized medicine |
| Part 1: A personal opinion on personalized medicine ABSTRACT: For biomarkers there is a consensus definition from 2001. However, there is no similar thing for personalized medicine. This has created some confusion. Actually, I believe that conceptually there are two contrasting viewpoints on what personalized medicine covers. Besides, there are differences on a smaller scale regarding the technical complexity of the individual information to be used in a treatment strategy. Based on a series of scenarios, I will discuss these issues. Part 2: Drug development programs leading to personalized medicine ABSTRACT: Part 1 sketched a few possibilities for personalized medicine strategies. I will start by summarizing the possibilities, not as a formal definition but rather as an informal description of the possibilities. For each of these possibilities I will discuss what development programs are needed for progressing them. There will be examples (mostly from oncology) as well as more general considerations. |
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| 14. Nov | 10:00-11:00 i lokale 4.39 | Jesper Lund PhD student from Epidemiology, Biostatistics and Biodemography, SDU DNA methylation linked to all-cause mortality in older people: An epigenome-wide association study |
| 6. Nov | 13:00-14:00 i lokale 4.39 | Lucas Calais Ferreira PhD Student from The Australian Twin Registry, Melbourne Building networks and capacity for twin research |
| ABSTRACT: The participation of twins in research enables discovering the way genetic and environmental factors combine to influence what it is to be human. Twin registries and researchers play an important role in addressing challenges related to health and well-being in populations through the use of twin study designs. I will discuss how early-career researchers are contributing to capacity building in twin research by developing a global network of researchers, professionals and twin registries, and building a catalogue of twin data and biospecimens available for international scientific collaboration. I will also discuss the establishment of the Brazilian Twin Registry and the challenges involved with such initiative. Finally, I will present Twins Research Australia’s knowledge translation plan and debate ideas related to engagement with members and other stakeholders in a twin registry. | ||
| 23. Maj | 11:00-12:00 i lokale 4.39 | Philip Hougaard & Jacob von Hjelmborg Lundbeck and University of Southern Denmark Survival of Danish twins born 1870-2000 - preliminary report |
| ABSTRACT: Hougaard, Harvald and Holm (JASA, 1992) used frailty models to consider the survival of same-sex Danish twins born between 1881-1930 with follow-up until 1980 for twins where both were alive at age 15. This presentation gives an update to that analysis. For the birth cohorts 1870-1930, same-sex twins, where both were alive at age 6, are considered. For the birth cohorts 1931-2000, all twins are included. Follow-up is to 2016. Besides presenting the results, I will discuss the appropriateness of shared frailty models for studying this problem. | ||
| 27. Apr. | 13:00-14:00 i lokale 4.48 | James Curtsinger Professor in the Department of Ecology, Evolution, and Behavior at the University of Minnesota Retired flies, mortality plateaus, and the evolution of senescence in Drosophila melanogaster |
| ABSTRACT: A leading explanation for late-life mortality plateaus in Drosophila and other species is population heterogeneity - unobserved variation between individuals in their susceptibility to death leads to changes in cohort composition over time, altering mortality dynamics. Recent work argues for a fundamental change in our understanding of mortality plateaus in Drosophila. Analysis of fecundity data from individually maintained females suggests that mortality plateaus are not limited to old age, and are not explained by population heterogeneity. Plateaus arise when individual flies transition from the working stage, a period of high fecundity and survival, to the retired stage, a terminal state of limited fecundity. Population mortality can be decomposed into component trajectories that include youthful plateaus. The analysis extends to at least two other dipteran species, and has implications for our understanding of mutational variance and trade-offs in life-history evolution. | ||
| 25. Apr. | 13:00-14:00 i lokale 1.36 | Andreas Kryger Jensen Assistant Professor at Department of Public Health, KU Semi-parametric repression for warped density functions |
| 22. Feb. | 10:15-11:15 i lokale 4.39 | Philip Hougaard Vice President of Biometrics at Lundbeck and external professor at SDU Statistical analysis of recurrent events, based on simple frailty models, and extensions |
Program 2016
| 19. Dec. | 13:00-14:00 i lokale 4.39 | Vibeke Andersen Professor from the Department of Molecular Medicine, SDU Gene-environment interaction analyses in relation to colorectal cancer - as a method to identify underlying biological pathways |
| 14. Dec. | 10:15-11:15 i lokale 1.36 | Philip Hougaard Vice President of Biometrics at Lundbeck and external professor at SDU Group-sequential trial methods – choice of limit stopping for futility and/or effect |
| 9. Dec. | 10:00-11:00 i lokale 4.39 | Janne Pitkäniemi Director of Statistics at the Finnish Cancer Registry Heritability estimation of early onset cancer of family based data - done in a Bayesian fashion |
| 15. Nov. | 14:00-15:00 i lokale 4.39 | Kang Li PhD student, Copenhagen University Novel mathematical neural models for visual attention |
| 22. Sep. | 13:00-14:00 i lokale 4.39 | Shuai Li University of Melbourne and at the Australian Twins and Sisters Mammographic Study Familial aspects of DNA methylation |
| 10. Jun. | 11:00-12:00 i lokale 4.39 | Rudi G.J. Westendorp Faculty of Health and Medical Sciences at Copenhagen University Succesful ageing |
| HEADLINES: Our inability to successfully predict mortality, the lenght of life for individuals; A citation network analysis of the literature on what is considered success (http://www.maturitas.org/article/S0378-5122%2816%2930082-2/abstract); That success for older people has sobering little to do with health in strict sense. |
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| 10. Maj | 13:00-14:00 i lokale 4.39 | Weilong Li IMADA A Computer Simulation on Power Advantage of Using Disease Concordant Twins in Genetic Association Study |
| 28. Apr. | 11:00-12:00 i lokale 4.39 | Thomas Werge and Alfonso Buil Demur Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans Twin studies with OMICS data |
| 18. Apr. | 10:00-10:30 i lokale 4.39 | Jonas Mengel-From EBB - Syddansk Universitet microRNA and cognitive function in elderly twins |
| 18. Apr. | 10:30-11:00 i lokale 4.39 | Vladimir Canudas-Romo MaxO - Syddansk Universitet Record and maximum life expectancy: actual and potential values |
| 4. Apr. | 10:00-10:30 i lokale 4.39 | Jim Vaupel MaxO - Syddansk Universitet The temporal scaling of Caenorhabditis elegans Ageing |
| 21. Mar. | 10:30-12:00 i lokale 4.39 |
Francisco Villavicencio Bayesian Inference to Estimate Mortality from Incomplete Historical Data Jonas Schöley The Effective Use of Colour in Visualization (How to Avoid Pink Fluffy Unicorns Dancing On Rainbows) Catalina Torres: The Scandinavian Advantage: A Comparative Analysis of Life Expectancy at Birth by Sex in Four European Countries during the 19th Century Alle fra MaxO - Syddansk Universitet |
| 7. Mar. | 10:00-11:00 i lokale 4.39 | Jim Vaupel Introduction on the cluster Work Jim Oeppen Forecasting mortality by causes of death Marie-Pier Bergeron-Boucher Coherent modeling and forecasting of mortality patterns for subpopulations using multi-way analysis of composition Alle fra MaxO - Syddansk Universitet |
| 3. Mar. | 11:15-12:00 i lokale 4.39 | Bjørn Heine Strand Norwegian Institute of Public Health - Oslo The Tromsø study Ellen Langballe & Vegard Skirbekk Norwegian Institute of Public Health - Oslo The NORSE study |
| 23. Feb. | 10:00-11:00 i lokale 4.48 |
Ursula M Staudinger, Professor of Psychology Columbia University and the Founding Director of the Robert N. Butler Columbia Aging Center Plasticity of Human Aging |
| ABSTRACT: Neither human development nor aging are biologically or contextually determined. Instead they are probabilistic in nature, as they are the result of continuous interactions between biological and sociocultural forces. This is why an individual’s developmental trajectory in a given domain of functioning can take many different shapes within biological limits. This intraindividual variability has been labeled ‘plasticity of human development’. Examples from cognitive and personality functioning are presented to illustrate the plasticity of aging and its limits. The limits of plasticity have been identified mainly in very old age. Given the findings accumulating from the field of epigenetics, the question arises whether these age-related limits are biological constants that outlast even sociocultural change or whether these limits also underlie historical change. Given the plasticity of human development and aging, it is worthwhile compiling more and more scientific knowledge about which characteristics of sociocultural contexts are optimal for unfolding the potential of aging. Also, it is crucial to systematically collect cohort- and country-comparative longitudinal data to being able to better capture such influences. | ||
| 22. Feb. | 10:00-10:30 i lokale 4.39 | Birgit Debrabant EBB - Syddansk Universitet A little bit about chronological age, perceived age and methylation age |
| 22. Feb. | 10:30-11:00 i lokale 4.39 | Uli Steiner MaxO - Syddansk Universitet Increasing life expectancy and change in perceived age across time |
| 9. Feb. | 9:00-9:45 i lokale 4.39 | Eero Vuoksimaa, Adjunct Professor Institute of Behavioral Sciences, University of Helsinki Cognitive ability and brain size: insights from twins studies on cortical surface area and cortical thickness |
| 8. Feb. | 10:00-10:30 i lokale 4.39 | Ulrich Halekoh EBB - Syddansk Universitet Black spot detection for traffic accidents and some shiny p-value explanation |
| 25. Jan. | 10:00-10:30 i lokale 4.48 | Dorthe Almind Pedersen EBB - Syddansk Universitet Psychiatric Disorders in Individuals with Non-Syndromic Oral Cleft: Register-Based Cohort Studies |
| 12. Jan. | 11:15-12:00 i lokale 4.39 | Matt McGue, Professor of psychology University of Minnesota How do we measure change? |
Program 2015
| 17. Dec. | 13:15-13:45 i lokale 4.39 | Anders J Svendsen, Klinisk lektor EBB - Syddansk Universitet Rheumatoid Arthritis: From an Epigenetic Viewpoint |
| 11. Dec. | 10:00-11:00 i lokale 4.39 |
Zsolt Illes, Professor Department of Neurology, SDU Previous research and the plans of a new comprehensive twin study on multiple sclerosis (MS) |
| 3. Dec. | 13:15-13:45 i lokale 4.39 | Marianne Nygaard, Post.doc. DARC - Syddansk Universitet The 5q33.3 Longevity Locus and Functional Capacity in the Oldest-old |
| 25. Nov. | 13:15-14:00 i lokale 4.39 | Bo Markussen, Lektor, KU Laboratorium for Anvendt Statistik på KU: Hvorfor, hvad og hvordan? |
| 23. Nov. | 10:00-10:30 i lokale 4.39 |
Maarten Wensink, Post.doc. MaxO - Syddansk Universitet - IST Insights from a simple cancer model. |
| 16. Nov. | 10:00-10:15 i lokale 4.39 |
Catalina Torres MaxO - Syddansk Universitet - IST The historical rise in life expectancy at birth: how exceptional were some Scandinavian countries during the early 19th century? |
| 16. Nov. | 10:15-10:30 i lokale 4.39 | Johanna Stärk, PhD Student MaxO - Syddansk Universitet, Biologi Decision making in the conservation of Europe’s threatened species |
| 12. nov. | 10:15-11:00 i lokale 4.39 | Dr. Rebecca Graff Cancer Epidemiology, Harvard School of Public Health Molecular Subclassification of Prostate Cancer: The Epidemiology of TMPRSS2:ERG |
| 6. nov. | 11:00-12:00 i lokale 4.39 |
Niels Keiding, Professor Emeritus Folkesundhedsvidenskab, KU The prehistory of medical statistics in Denmark in the 19th century |
| 27. okt. | 13:15-13:45 in room 4.39 |
Mette S Thinggaard, Post.doc DARC - Syddansk Universitet FOXO3A SNPs, DNA methylation and bone related phenotypes |
| 23. okt. | 10:15-10:30 i lokale 4.39 |
Signe Høi Rasmussen, Ph.d. stud. EBB - Syddansk Universitet The 1915 Birth Cohort Study – Health Profiles of 100 Year Old Danes Including Cognitive and Cardiovascular Assessment |
| 29. sept. | 13:15-13:45 i lokale 4.39 | Mikael Thinggaard, Ph.d. stud. DARC - Syddansk Universitet Advances in survival among the very old are seen across the spectrum of health and functioning |
| 11. sept. | 14:00-15:00 i lokale 4.39 |
Karen Helene Ørstavik, Rikshospitalet, University of Oslo X chromosome inactivation and clinical practice |
| 10. sept. | 14:00-15:00 i lokale 4.39 |
Mette Wulf Christensen, Ph.d. stud. Fertilitetsklinikken, Aarhus Universitetshospital Is early ovarian ageing associated to an accelerated general somatic ageing? |
| 9. sept. | 10:00-10:45 i lokale 4.39 | Bjarki Djurhuus, Syddansk Universitet Cholesteatoma - Occurence and risk factors |
| 13. aug. | 11:30-12:15 i lokale 4.39 | Axel Börsch-Supan, MEA - Munich Center for the Economics of Aging SHARE project - Survey on Health, Ageing and Retirement in Europe |
| 21. maj | 13:00-14:00 i lokale 4.39 | Philip Hougaard, Syddansk Universitet, H. Lundbeck A/S Optimal design of clinical trials, based on linear and nonlinear models Abstract |
| 13. maj | 14:00-15:00 i lokale 4.39 | Anette Grønning, Institut for Kulturvidenskab, SDU Slave of the inbox? Abstract |
| 10. marts | 10:00-10:30 i lokale 4.39 | Karen Andersen-Ranberg, Syddansk Universitet The European SHARE project Abstract |
| 2. marts | 11:00-12:00 i lokale 4.39 |
Manuel Matthiesen, Århus Universitet Polygenic risk prediction - a case report for schizophrenia Abstract |
| 6. januar | 14:30-15:30 i lokale 4.39 |
Claus Ekstrøm, Københavns Universitet Interactive and dynamic Graphics in teaching, presentation and research Abstract |
| 5. januar | 10:00-10:30 i lokale 4.39 | James W Vaupel, MaxO Stockholm, Dementia and Jeanne Calment Indlæg fra Nobel Week Dialogue i Stockholm. |
Program 2014
| 15. december | 10:00-10:30 i lokale 4.39 | Virginia Zarulli, Adam Lenart & Vladimir Canudas-Romo, MaxO Am I Halfway? Life lived = expected life |
| 24. november | 10:00-11:00 i lokale 4.39 | Søren Kjærsgaard, Århus Universitet Improving Danish mortality forecasts using cohort models, error correction models and coherent models Ideer til en ph.d. |
| 31. oktober | 10:00-11:00 i lokale 4.39 |
Postdoc Søren Møller, Biostatistisk Enhed, EBB Methods for studying heritability of cancer diagnosis using twins Se Abstract |
| 22. oktober | 11:00-12:00 i lokale 4.39 | Professor Jacob v.B. Hjelmborg og Associate Professor Ulrich Halekoh, Biostatistisk Enhed, EBB Increased Resemblance of Telomere Length in Dizygotic Twins of Older Fathers Se Abstract |
| 12. august | 11:30-12:30 i lokale 4.39 | PhD Student Corine Baayen, Department of Public Health, Section of Biostatistics, KU Testing effect of a drug using multiple nested models for the dose-response Se Abstract |
| 4. juli | 11:15-12:15 i lokale 4.39 | PhD Student Chuncheng Xu Gene, environment and cognitive ability: A Chinese twin aging study Se Abstract |
| 1. juli | 14:15-15:15 i lokale 4.39 |
Postdoctoral Research Associate, Hannes Schwandt, Princeton University Seasonal Patterns in Health at Birth - And Why Flu Could Be to Blame Se Abstract |
| 11. juni |
10:00-11:00 i lokale 1.36 (Biostat-køkken): |
Biostat Seminar: PhD Student Wagner Hugo Bonat Multivariate Generalized Linear Covariance Models Se Abstract |
| 14. maj | 14:15-15:15 i lokale 4.39 |
MD Carol Khan The genetic overlap between type 2 diabetes and depression Se Abstract |
| 18. mar. | 10:00-11:00 i lokale 4.39 |
Associate Professor Vladimir Canudas-Romo The Nordic gap in cohort survival Se Abstract |
| 11. mar. | 10:15-11:00 i lokale 3.72 |
PhD student Wagner Bonat Regression models with responses on the unit interval: specification, estimation and comparison Se Abstract |
| 24. feb. | 10:00-11:00 i lokale 4.39 |
Phillip Hougaard Double censoring: Estimating the distribution of the time between two events, when the time of the first event is not observed precisely Se Abstract |
| 11. feb. | 10:15-11:15 i lokale 2.35 |
Head of Statistics, Klaus Kaae Andersen and PhD student, Luise Cederkvist Kristiansen at the Danish Cancer Society Advanced statistical models for familial aggregation of cancer Se Abstract |
| 10. jan. | 11:00-12:00 i lokale 4.39 |
MD and PhD Constance Jensina Ulff-Møller Heredity and Epigenetics in Systemic Lupus Erythematosus Se Abstract |