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Seminarer & Events

Adresse:
Epidemiologi og Biostatistik
Syddansk Universitet (SDU) 
J.B. Winsløws Vej 9A. ("Kort")
Sædvanligvis: Lokale 4.39, 3. sal 

For information om kommende EB seminarer og for offentliggørelse af EB seminar præsentationer: SEMINAR BOOKING 

Program 2018

16. Maj  13:00-15:00 i lokale 25.111  Kaare Christensen
Professor at Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark
Applied Twin Research: Aging and Longevity
    ABSTRACT: Se Ph.d.-kursus: Analysis of Twin Data in Health Research

Lokale: 25.111 - J.B. Winsløws Vej 25, Odense SØ - Find vej 
14. Maj 13:00-14:00 i lokale 25.111 Jaakko Kaprio
Professor at Genetic Epidemiology, Department of Public Health, University of Helsinki, Finland
The Future of Twin Studies
    ABSTRACT: Se Ph.d.-kursus: Analysis of Twin Data in Health Research

Lokale: 25.111 - J.B. Winsløws Vej 25, Odense SØ - Find vej 
23. April  13:00-13:30 i lokale 4.39  Javier De La Fuente
Department of psychiatry, School of Medicine, Universidad Autónoma de Madrid, Spain
Longitudinal associations of sensory and cognitive functioning: evidences of the sensory deprivation hypothesis in the English Longitudinal Study of Ageing  
    ABSTRACT: Several cross-sectional and longitudinal studies have shown a link between sensory and cognitive functioning in the elderly. According to the sensory deprivation hypothesis, there is a causal link between impaired perception and cognitive decline, since age-related declines in sensory functioning reduce the quality of sensory stimuli input, which in turn have long-term negative effects on cognitive capacity due to neural atrophy. 

This study aims at assessing the associations of self-reported visual and hearing difficulties with cognitive functioning in a time-span of eight years in a nationally representative sample of 3508 participants aged 60 and over from the English Longitudinal Study of Ageing.
12. Marts 14:00-15:00 i lokale 4.39  Paolo Caserotti 
Associate Professor at Department of Sports Science and Clinical Biomechanics, SDU
Exercise Referral Schemes enhanced by Self-Management Strategies to battle sedentary behaviour: recruitment challenges, follow-up  and needs for new action plans
    ABSTRACT: The SITLESS project is a large-scale trial that evaluates the long-term effect of a physical activity-based intervention combined with self-management strategies in older adults to decrease sedentary behaviour community-dwelling older adults 65+ and the only multicenter trial ever conducted in the European Union with this purpose.

SITLESS primary aim is to assess the long-term effectiveness (18 month follow-up) of a complex intervention on sedentary behaviour (SB) and physical activity (PA) in 65+ community dwelling older citizens population based on existing exercise referral schemes (ERS) enhanced by self-management-strategies (SMS). Four pilot sites (Denmark, Ireland Germany and Spain) have enrolled over 1400 community-dwelling older adults 65+ using National existing health care pathways. Primary and secondary health outcomes including “health”, quality of life, functional performance, muscle mechanical function psychosocial outcomes are assessed before, after (4 months) and 18 months following the end of the intervention.  The study is designed a three-armed pragmatic randomised controlled trial.

One of the key of the project is to provide new evidence on how to design, implement and evaluate a complex intervention enhancing exercise-referral schemes (ERS) with self-management strategies (SMS) to decrease sedentary behaviour in community-dwelling older adults, considering end-users’ interests, forming cooperative teams of stakeholders and distributing actions and decisions. We aim to improve physical function and quality of life producing sustainable changes.

The background, enrollment and intervention status of the project will be presented. The consortium is seeking for advices to tackle several challenges including recruitment delays and drop-out rate and which scientific consequences this may have on the overall aims. Successful outcomes of the project are potentially important in setting the evidence-based foundations for future European public health policies in this area.
Project has been funded under the program Horizon 2020: Number 634270 - (PI: Coll Planas L)  01/05/15- 30/04/19 (4,8 mI €)
The trial registration was published nearly one year ago

The SITLESS project: exercise referral schemes enhanced by self-management strategies to battle sedentary behaviour in older adults: study protocol for a randomised controlled trial.
Giné-Garriga M, Coll-Planas L, Guerra M, Domingo À, Roqué M, Caserotti P, Denkinger M, Rothenbacher D, Tully MA, Kee F, McIntosh E, Martín-Borràs C, Oviedo GR, Jerez-Roig J, Santiago M, Sansano O, Varela G, Skjødt M, Wirth K, Dallmeier D, Klenk J, Wilson JJ, Blackburn NE, Deidda M, Lefebvre G, González D, Salvà A.
Trial. 2017 May 18; 18(1):221

Invited by: Kaare Christensen.

Program 2017

 19. Dec 13:00-15:00 i lokale 4.39  Phillip Hougaard
Vice President of Biometrics at Lundbeck and external professor, SDU
Personalized medicine
    Part 1: A personal opinion on personalized medicine
ABSTRACT: For biomarkers there is a consensus definition from 2001. However, there is no similar thing for personalized medicine. This has created some confusion. Actually, I believe that conceptually there are two contrasting viewpoints on what personalized medicine covers. Besides, there are differences on a smaller scale regarding the technical complexity of the individual information to be used in a treatment strategy. Based on a series of scenarios, I will discuss these issues.

Part 2: Drug development programs leading to personalized medicine
ABSTRACT:
Part 1 sketched a few possibilities for personalized medicine strategies. I will start by summarizing the possibilities, not as a formal definition but rather as an informal description of the possibilities. For each of these possibilities I will discuss what development programs are needed for progressing them. There will be examples (mostly from oncology) as well as more general considerations.
14. Nov 10:00-11:00 i lokale 4.39 Jesper Lund
PhD student from Epidemiology, Biostatistics and Biodemography, SDU
DNA methylation linked to all-cause mortality in older people: An epigenome-wide association study 

6. Nov 13:00-14:00 i lokale 4.39 Lucas Calais Ferreira
PhD Student from The Australian Twin Registry, Melbourne
Building networks and capacity for twin research 
    ABSTRACT: The participation of twins in research enables discovering the way genetic and environmental factors combine to influence what it is to be human. Twin registries and researchers play an important role in addressing challenges related to health and well-being in populations through the use of twin study designs. I will discuss how early-career researchers are contributing to capacity building in twin research by developing a global network of researchers, professionals and twin registries, and building a catalogue of twin data and biospecimens available for international scientific collaboration. I will also discuss the establishment of the Brazilian Twin Registry and the challenges involved with such initiative. Finally, I will present Twins Research Australia’s knowledge translation plan and debate ideas related to engagement with members and other stakeholders in a twin registry.
23. Maj 11:00-12:00 i lokale 4.39 Philip Hougaard & Jacob von Hjelmborg
Lundbeck and University of Southern Denmark
Survival of Danish twins born 1870-2000 - preliminary report
    ABSTRACT: Hougaard, Harvald and Holm (JASA, 1992) used frailty models to consider the survival of same-sex Danish twins born between 1881-1930 with follow-up until 1980 for twins where both were alive at age 15.  This presentation gives an update to that analysis. For the birth cohorts 1870-1930, same-sex twins, where both were alive at age 6, are considered. For the birth cohorts 1931-2000, all twins are included. Follow-up is to 2016. Besides presenting the results, I will discuss the appropriateness of shared frailty models for studying this problem.
27. Apr. 13:00-14:00 i lokale 4.48 James Curtsinger
Professor in the Department of Ecology, Evolution, and Behavior at the University of Minnesota
Retired flies, mortality plateaus, and the evolution of senescence in Drosophila melanogaster
    ABSTRACT: A leading explanation for late-life mortality plateaus in Drosophila and other species is population heterogeneity - unobserved variation between individuals in their susceptibility to death leads to changes in cohort composition over time, altering mortality dynamics. Recent work argues for a fundamental change in our understanding of mortality plateaus in Drosophila. Analysis of fecundity data from individually maintained females suggests that mortality plateaus are not limited to old age, and are not explained by population heterogeneity. Plateaus arise when individual flies transition from the working stage, a period of high fecundity and survival, to the retired stage, a terminal state of limited fecundity. Population mortality can be decomposed into component trajectories that include youthful plateaus. The analysis extends to at least two other dipteran species, and has implications for our understanding of mutational variance and trade-offs in life-history evolution.    
25. Apr. 13:00-14:00 i lokale 1.36 Andreas Kryger Jensen
Assistant Professor at Department of Public Health, KU
Semi-parametric repression for warped density functions
22. Feb. 10:15-11:15 i lokale 4.39 Philip Hougaard
Vice President of Biometrics at Lundbeck and external professor at SDU
Statistical analysis of recurrent events, based on simple frailty models, and extensions

Program 2016

19. Dec. 13:00-14:00 i lokale 4.39 Vibeke Andersen
Professor from the Department of Molecular Medicine, SDU
Gene-environment interaction analyses in relation to colorectal cancer - as a method to identify underlying biological pathways
14. Dec. 10:15-11:15 i lokale 1.36 Philip Hougaard
Vice President of Biometrics at Lundbeck and external professor at SDU
Group-sequential trial methods – choice of limit stopping for futility and/or effect
9. Dec. 10:00-11:00 i lokale 4.39 Janne Pitkäniemi
Director of Statistics at the Finnish Cancer Registry
Heritability estimation of early onset cancer of family based data - done in a Bayesian fashion
15. Nov. 14:00-15:00 i lokale 4.39 Kang Li
PhD student, Copenhagen University
Novel mathematical neural models for visual attention
22. Sep. 13:00-14:00 i lokale 4.39 Shuai Li
University of Melbourne and at the Australian Twins and Sisters Mammographic Study
Familial aspects of DNA methylation
10. Jun. 11:00-12:00 i lokale 4.39 Rudi G.J. Westendorp
Faculty of Health and Medical Sciences at Copenhagen University
Succesful ageing
 
    HEADLINES:
Our inability to successfully predict mortality, the lenght of life for individuals;  
A citation network analysis of the literature on what is considered success (http://www.maturitas.org/article/S0378-5122%2816%2930082-2/abstract);
That success for older people has sobering little to do with health in strict sense.  
10. Maj 13:00-14:00 i lokale 4.39 Weilong Li
IMADA
A Computer Simulation on Power Advantage of Using Disease Concordant Twins in Genetic Association Study
28. Apr. 11:00-12:00 i lokale 4.39 Thomas Werge and Alfonso Buil Demur
Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans

Twin studies with OMICS data
 18. Apr. 10:00-10:30 i lokale 4.39  Jonas Mengel-From
EBB - Syddansk Universitet
microRNA and cognitive function in elderly twins
 
 18. Apr. 10:30-11:00 i lokale 4.39  Vladimir Canudas-Romo
MaxO - Syddansk Universitet
Record and maximum life expectancy: actual and potential values 
 4. Apr. 10:00-10:30 i lokale 4.39  Jim Vaupel
MaxO - Syddansk Universitet
The temporal scaling of Caenorhabditis elegans Ageing 
21. Mar. 10:30-12:00 i lokale 4.39  Francisco Villavicencio
Bayesian Inference to Estimate Mortality from Incomplete Historical Data

Jonas Schöley
The Effective Use of Colour in Visualization (How to Avoid Pink Fluffy Unicorns Dancing On Rainbows)

Catalina Torres:
The Scandinavian Advantage: A Comparative Analysis of Life Expectancy at Birth by Sex in Four European Countries during the 19th Century


Alle fra MaxO - Syddansk Universitet
7. Mar.  10:00-11:00 i lokale 4.39  Jim Vaupel
Introduction on the cluster Work

Jim Oeppen
Forecasting mortality by causes of death
 
Marie-Pier Bergeron-Boucher
Coherent modeling and forecasting of mortality patterns for subpopulations using multi-way analysis of composition

Alle fra MaxO - Syddansk Universitet
3. Mar.  11:15-12:00 i lokale 4.39  Bjørn Heine Strand
Norwegian Institute of Public Health - Oslo 
The Tromsø study

Ellen Langballe & Vegard Skirbekk
Norwegian Institute of Public Health - Oslo 
The NORSE study 
23. Feb.  10:00-11:00 i lokale 4.48  Ursula M Staudinger, Professor of Psychology
Columbia University and the Founding Director of the Robert N. Butler Columbia Aging Center
Plasticity of Human Aging             
    ABSTRACT:  Neither human development nor aging are biologically or contextually determined. Instead they are probabilistic in nature, as they are the result of continuous interactions between biological and sociocultural forces. This is why an individual’s developmental trajectory in a given domain of functioning can take many different shapes within biological limits. This intraindividual variability has been labeled ‘plasticity of human development’. Examples from cognitive and personality functioning are presented to illustrate the plasticity of aging and its limits. The limits of plasticity have been identified mainly in very old age. Given the findings accumulating from the field of epigenetics, the question arises whether these age-related limits are biological constants that outlast even sociocultural change or whether these limits also underlie historical change. Given the plasticity of human development and aging, it is worthwhile compiling more and more scientific knowledge about which characteristics of sociocultural contexts are optimal for unfolding the potential of aging. Also, it is crucial to systematically collect cohort- and country-comparative longitudinal data to being able to better capture such influences.
22. Feb. 10:00-10:30 i lokale 4.39  Birgit Debrabant
EBB - Syddansk Universitet
A little bit about chronological age, perceived age and methylation age 
22. Feb.  10:30-11:00 i lokale 4.39  Uli Steiner
MaxO - Syddansk Universitet
Increasing life expectancy and change in perceived age across time 
9. Feb. 9:00-9:45 i lokale 4.39  Eero Vuoksimaa, Adjunct Professor
Institute of Behavioral Sciences, University of Helsinki
Cognitive ability and brain size: insights from twins studies on cortical surface area and cortical thickness 
8. Feb. 10:00-10:30 i lokale 4.39  Ulrich Halekoh
EBB - Syddansk Universitet
Black spot detection for traffic accidents and some shiny p-value explanation 
25. Jan. 10:00-10:30 i lokale 4.48  Dorthe Almind Pedersen
EBB - Syddansk Universitet
Psychiatric Disorders in Individuals with Non-Syndromic Oral Cleft: Register-Based Cohort Studies 
12. Jan.  11:15-12:00 i lokale 4.39 Matt McGue, Professor of psychology
University of Minnesota
How do we measure change?

Program 2015

17. Dec. 13:15-13:45 i lokale 4.39 Anders J Svendsen, Klinisk lektor
EBB - Syddansk Universitet
Rheumatoid Arthritis: From an Epigenetic Viewpoint
11. Dec. 10:00-11:00 i lokale 4.39 Zsolt Illes, Professor
Department of Neurology, SDU
Previous research and the plans of a new comprehensive twin study on multiple sclerosis (MS)
3. Dec. 13:15-13:45 i lokale 4.39 Marianne Nygaard, Post.doc.
DARC - Syddansk Universitet
The 5q33.3 Longevity Locus and Functional Capacity in the Oldest-old
25. Nov. 13:15-14:00 i lokale 4.39 Bo Markussen, Lektor, KU
Laboratorium for Anvendt Statistik på KU: Hvorfor, hvad og hvordan?
23. Nov. 10:00-10:30 i lokale 4.39 Maarten Wensink, Post.doc.
MaxO - Syddansk Universitet - IST
Insights from a simple cancer model.
16. Nov. 10:00-10:15 i lokale 4.39 Catalina Torres
MaxO - Syddansk Universitet - IST
The historical rise in life expectancy at birth: how exceptional were some Scandinavian countries during the early 19th century?
16. Nov. 10:15-10:30 i lokale 4.39  Johanna Stärk, PhD Student
MaxO - Syddansk Universitet, Biologi
Decision making in the conservation of Europe’s threatened species
12. nov. 10:15-11:00 i lokale 4.39  Dr. Rebecca Graff
Cancer Epidemiology, Harvard School of Public Health
Molecular Subclassification of Prostate Cancer: The Epidemiology of TMPRSS2:ERG
6. nov. 11:00-12:00 i lokale 4.39 Niels Keiding, Professor Emeritus
Folkesundhedsvidenskab, KU
The prehistory of medical statistics in Denmark in the 19th century 
27. okt. 13:15-13:45 in room 4.39 Mette S Thinggaard, Post.doc
DARC - Syddansk Universitet
FOXO3A SNPs, DNA methylation and bone related phenotypes
23. okt. 10:15-10:30 i lokale 4.39 Signe Høi Rasmussen, Ph.d. stud.
EBB - Syddansk Universitet
The 1915 Birth Cohort Study – Health Profiles of 100 Year Old Danes Including Cognitive and Cardiovascular Assessment
29. sept. 13:15-13:45 i lokale 4.39 Mikael Thinggaard, Ph.d. stud.
DARC - Syddansk Universitet
Advances in survival among the very old are seen across the spectrum of health and functioning
11. sept.  14:00-15:00 i lokale 4.39  Karen Helene Ørstavik, Rikshospitalet, University of Oslo
X chromosome inactivation and clinical practice
10. sept.  14:00-15:00 i lokale 4.39  Mette Wulf Christensen, Ph.d. stud. 
Fertilitetsklinikken, Aarhus Universitetshospital
Is early ovarian ageing associated to an accelerated general somatic ageing?
9. sept. 10:00-10:45 i lokale 4.39  Bjarki Djurhuus, Syddansk Universitet
Cholesteatoma - Occurence and risk factors 
13. aug. 11:30-12:15 i lokale 4.39  Axel Börsch-Supan, MEA - Munich Center for the Economics of Aging
SHARE project - Survey on Health, Ageing and Retirement in Europe
21. maj 13:00-14:00 i lokale 4.39  Philip Hougaard, Syddansk Universitet, H. Lundbeck A/S
Optimal design of clinical trials, based on linear and nonlinear models
Abstract
13. maj 14:00-15:00 i lokale 4.39 Anette Grønning, Institut for Kulturvidenskab, SDU
Slave of the inbox?
Abstract
10. marts 10:00-10:30 i lokale 4.39  Karen Andersen-Ranberg, Syddansk Universitet
The European SHARE project
Abstract
2. marts 11:00-12:00 i lokale 4.39  Manuel Matthiesen, Århus Universitet
Polygenic risk prediction - a case report for schizophrenia
Abstract
6. januar 14:30-15:30 i lokale 4.39  Claus Ekstrøm, Københavns Universitet
Interactive and dynamic Graphics in teaching, presentation and research
Abstract
5. januar 10:00-10:30 i lokale 4.39  James W Vaupel, MaxO
Stockholm, Dementia and Jeanne Calment
Indlæg fra Nobel Week Dialogue i Stockholm.

Program 2014

15. december 10:00-10:30 i lokale 4.39  Virginia Zarulli, Adam Lenart & Vladimir Canudas-Romo, MaxO
Am I Halfway? Life lived = expected life 
24. november  10:00-11:00 i lokale 4.39  Søren Kjærsgaard, Århus Universitet
Improving Danish mortality forecasts using cohort models, error correction models and coherent models
Ideer til en ph.d.
31. oktober 10:00-11:00 i lokale 4.39   Postdoc Søren Møller, Biostatistisk Enhed, EBB
Methods for studying heritability of cancer diagnosis using twins
Se Abstract
22. oktober 11:00-12:00 i lokale 4.39  Professor Jacob v.B. Hjelmborg og Associate Professor Ulrich Halekoh, Biostatistisk Enhed, EBB
Increased Resemblance of Telomere Length in Dizygotic Twins of Older Fathers
Se Abstract
12. august  11:30-12:30 i lokale 4.39  PhD Student Corine Baayen, Department of Public Health, Section of Biostatistics, KU
Testing effect of a drug using multiple nested models for the dose-response
Se Abstract
4. juli  11:15-12:15 i lokale 4.39  PhD Student Chuncheng Xu
Gene, environment and cognitive ability: A Chinese twin aging study
Se Abstract 
1. juli  14:15-15:15 i lokale 4.39  Postdoctoral Research Associate, Hannes Schwandt, Princeton University
Seasonal Patterns in Health at Birth - And Why Flu Could Be to Blame
Se Abstract
11. juni  10:00-11:00
i lokale 1.36
 
(Biostat-køkken):
Biostat Seminar: PhD Student Wagner Hugo Bonat
Multivariate Generalized Linear Covariance Models
Se Abstract
14. maj 14:15-15:15
i lokale 4.39
MD Carol Khan
The genetic overlap between type 2 diabetes and depression
Se Abstract
18. mar. 10:00-11:00
i lokale 4.39
Associate Professor Vladimir Canudas-Romo
The Nordic gap in cohort survival
Se Abstract
11. mar.   10:15-11:00
i lokale 3.72
  
PhD student Wagner Bonat
Regression models with responses on the unit interval: specification, estimation and comparison
Se Abstract
24. feb.  10:00-11:00
i lokale 4.39
Phillip Hougaard
Double censoring: Estimating the distribution of the time between two events, when the time of the first event is not observed precisely
Se Abstract
11. feb. 10:15-11:15
i lokale 2.35
Head of Statistics, Klaus Kaae Andersen and PhD student, Luise Cederkvist Kristiansen at the Danish Cancer Society
Advanced statistical models for familial aggregation of cancer
Se Abstract
10. jan. 11:00-12:00
i lokale 4.39
MD and PhD Constance Jensina Ulff-Møller
Heredity and Epigenetics in Systemic Lupus Erythematosus
Se Abstract
Flere oplæg vil blive føjet til listen.

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