Epigenetic signatures of early-life events

Introduction

Susceptibility to common diseases is assumed to be “programmed” by poor nutrition early in life. Although with support in animal studies, direct evidence connecting fetal malnutrition and later health in humans has been sparse due to ethical and practical reasons. The 1959–1961 Chinese Famine with exceptionally long lasting time provides a unique opportunity to examine the effects of poor nutrition during fetal development and infancy in modifying the risk of adult-onset diseases.

Aim

The proposed project is the first large epigenomic study focusing on early life events and later life health. The project will be based on an existing collaboration network of Danish and Chinese scientists with expertise in studying complex diseases, genetic epidemiology, bioinformatics and public health.

Main Supervisor

Co-supervisors

Funding

Grant from the Det Frie Forskningsråd and Lundbeck Foundation.


Ph.d. studerende

Weilong Li

Kontakt

Har den store kinesiske hungersnød 1959-1961 påvirket børnenes genetiske udtryk i forhold til forældrenes?

Bevilling fra Det Frie Forskningsråd

EBB - Nyt

Genetisk Epidemiologi

Forskningsområde

Om: Genetik

Vi samler statistik ved hjælp af cookies for at forbedre brugeroplevelsen. Læs mere om cookies

Acceptér cookies