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Læbe-Ganespalte: Publikationsliste

Use of Psychotropic Medications and Visits to Psychiatrists and Psychologists among Individuals with Nonsyndromic Oral Clefts: A Population-Based Cohort Study

Pedersen DA, Hageman I, Wehby GL, Christensen K.

Birth Defects Res. 2017 Jul 3;109(11):824-835. Pubmed abstract

 

Oral Clefts and Academic Performance in Adolescence: The Impact of Anesthesia-Related Neurotoxicity, Timing of Surgery, and Type of Oral Clefts.

Clausen NG, Pedersen DA, Pedersen JK, Møller SE, Grosen D, Wehby GL, Christensen K, Hansen TG.

Cleft Palate Craniofac J. 2017 Jul;54(4):371-380. Pubmed abstract

 

Maternal alcohol binge-drinking in the first trimester and the risk of orofacial clefts in offspring: a large population-based pooling study

DeRoo LA, Wilcox AJ, Lie RT, Romitti PA, Pedersen DA, Munger RG, Moreno Uribe LM, Wehby GL.

Eur J Epidemiol. 2016 Oct;31(10):1021-1034. Pubmed abstract

 

Psychiatric Diagnoses in Individuals with Non-Syndromic Oral Clefts: A Danish Population-Based Cohort Study

Pedersen DA, Wehby GL, Murray JC, Christensen K.

PLoS One. 2016 May 25;11(5):e0156261. Pubmed abstract

 

Cholesteatoma risk in 8,593 orofacial cleft cases and 6,989 siblings: A nationwide study

Djurhuus BD, Skytthe A, Faber CE, Christensen K.

Laryngoscope. 2015 May;125(5):1225-9. Pubmed abstract

 

Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci

Leslie EJ, Taub MA, Liu H, Steinberg KM, Koboldt DC, Zhang Q, Carlson JC, Hetmanski JB, Wang H, Larson DE, Fulton RS, Kousa YA, Fakhouri WD, Naji A, Ruczinski I, Begum F, Parker MM, Busch T, Standley J, Rigdon J, Hecht JT, Scott AF, Wehby GL, Christensen K, Czeizel AE, Deleyiannis FW, Schutte BC, Wilson RK, Cornell RA, Lidral AC, Weinstock GM, Beaty TH, Marazita ML, Murray JC.
Am J Hum Genet. 2015 Mar;96(3):397-411. Pubmed abstract

Long-term effects of oral clefts on health care utilization: a sibling comparison

Pedersen MS, Wehby GL, Pedersen DA, Christensen K.
Eur J Health Econ. 2015 Jul;16(6):603-12. Pubmed abstract

Ethnic variation in oral cleft occurrence in Denmark 1981-2002

Pedersen GS, Pedersen DA, Mortensen LH, Andersen AM, Christensen K.

Cleft Palate Craniofac J. 2014 Nov;51(6):677-85. Pubmed asbtract
  

Candidate gene linkage approach to identify DNA variants that predispose to preterm birth

Bream EN, Leppellere CR, Cooper ME, Dagle JM, Merrill DC, Christensen K, Simhan HN, Fong CT, Hallman M, Muglia LJ, Marazita ML, Murray JC.
Pediatr Res. 2013 Feb;73(2):135-41. Pubmed abstract

Increased prevalence of congenital heart defects in monozygotic and dizygotic twins

Herskind AM, Almind Pedersen D, Christensen K.
Circulation. 2013 Sep;128(11):1182-8. Pubmed abstract 

1985-2012

Dietz A, Pedersen DA, Jacobsen R, Wehby GL, Murray JC, Christensen K.
Risk of breast cancer in families with cleft lip and palate.
Ann Epidemiol. 2012 Jan;22(1):37-42. Pubmed abstract

Jugessur A, Skare Ø, Lie RT, Wilcox AJ, Christensen K, Christiansen L, Nguyen TT, Murray JC, Gjessing HK.
X-linked genes and risk of orofacial clefts: evidence from two population-based studies in Scandinavia.
PLoS One. 2012;7(6):e39240. Pubmed abstract

Shi M, Murray JC, Marazita ML, Munger RG, Ruczinski I, Hetmanski JB, Wu T, Murray T, Redett RJ, Wilcox AJ, Lie RT, Jabs EW, Wu-Chou YH, Chen PK, Wang H, Ye X, Yeow V, Chong SS, Shi B, Christensen K, Scott AF, Patel P, Cheah F, Beaty TH.
Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts.
Am J Med Genet A. 2012 Apr;158A(4):784-94. Pubmed abstract

Wehby GL, Pedersen DA, Murray JC, Christensen K.
The effects of oral clefts on hospital use throughout the lifespan.
BMC Health Serv Res. 2012 Mar 9;12:58. Pubmed abstract

2011

Beaty TH, Ruczinski I, Murray JC, Marazita ML, Munger RG, Hetmanski JB, Murray T, Redett RJ, Fallin MD, Liang KY, Wu T, Patel PJ, Jin SC, Zhang TX, Schwender H, Wu-Chou YH, Chen PK, Chong SS, Cheah F, Yeow V, Ye X, Wang H, Huang S, Jabs EW, Shi B, Wilcox AJ, Lie RT, Jee SH, Christensen K, Doheny KF, Pugh EW, Ling H, Scott AF.
Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate. 
Genet Epidemiol. 2011 Sep;35(6):469-78. Pubmed abstract

Grosen D, Bille C, Petersen I, Skytthe A, Hjelmborg JB, Pedersen JK, Murray JC, Christensen K.
Risk of Oral Clefts in Twins.
Epidemiology. 2011 May;22(3):313-9. Pubmed abstract

Anshøj B, Grosen D, Christensen K.
Findes der “usynlige” læbeganespalter?
LLG-bladet 2011 Jan; 1:10-12.

Hansen TG, Pedersen JK, Henneberg SW, Pedersen DA, Murray JC, Morton NS, Christensen K.
Academic Performance in Adolescence after Inguinal Hernia Repair in Infancy: A Nationwide Cohort Study. 
Anesthesiology. 2011 May;114(5):1076-85. Pubmed abstract

Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC.
Fetal genetic risk of isolated cleft lip only versus isolated cleft lip and palate: A subphenotype analysis using two population-based studies of orofacial clefts in scandinavia.
Birth Defects Res A Clin Mol Teratol. 2011 Feb;91(2):85-92. Pubmed abstract

Yttri JE, Christensen K, Knudsen L, Bille C.
Reproductive patterns among Danish women with oral clefts.
Cleft Palate Craniofac J. 2010 Sep 8. [Epub ahead of print] Pubmed abstract

2010

Beaty TH, Murray JC, Marazita ML, Munger RG, Ruczinski I, Hetmanski JB, Liang KY, Wu T, Murray T, Fallin MD, Redett RA, Raymond G, Schwender H, Jin SC, Cooper ME, Dunnwald M, Mansilla MA, Leslie E, Bullard S, Lidral AC, Moreno LM, Menezes R, Vieira AR, Petrin A, Wilcox AJ, Lie RT, Jabs EW, Wu-Chou YH, Chen PK, Wang H, Ye X, Huang S, Yeow V, Chong SS, Jee SH, Shi B, Christensen K, Melbye M, Doheny KF, Pugh EW, Ling H, Castilla EE, Czeizel AE, Ma L, Field LL, Brody L, Pangilinan F, Mills JL, Molloy AM, Kirke PN, Scott JM, Arcos-Burgos M, Scott AF.
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4.
Nat Genet. 2010 Jun;42(6):525-9.

Bille C, Pedersen DA, Andersen AMN, Mansilla MA, Murray J, Christensen K, Ballard JL, Gorman EB, Cabrera RM, Finnell RH.
Autoantibodies to folate receptor alpha during early pregnancy and risk of oral clefts in Denmark.
Pediatric Research 2010 Mar;67(3):274-9.

Grosen D, Chevrier C, Skytthe A, Bille C, Mølsted K, Sivertsen A, Murray J, Christensen K.
A cohort study of recurrence patterns among more than 54,000 relatives of oral cleft cases in Denmark : support for the multifactorial threshold model of inheritance.
Journal of Medical Genetics 2010 Mar;47( 3): 162-8.

Grosen D, Bille C, Pedersen JK, Skytthe A, Murray JC, Christensen K.
Recurrence risk for offspring of twins discordant for oral cleft: a population-based cohort study of the Danish 1936-2004 cleft twin cohort.
Am J Med Genet A. 2010 Oct;152A(10):2468-74.

Grosen, Dorthe.
Oral Cleft Occurence and Familial Aggregation among Danish Twins and Singletons – 70 Years of Follow-up. 
Ph.d.-afhandling; Syddansk Universitet, Det Sundhedsvidenskabelige Fakultet, 2010.

Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC.
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
PLoS One. 2010 Jul 9;5(7):e11493. Pubmed abstract

2009

Bille C, Andersen AMN.
Preconception care : Public health campaigns are not reaching most women.
BMJ. British Medical Journal (International Ed.) 2009 Feb; 338():552-3.

Boyles AL, Wilcox AJ, Taylor JA, Shi M, Weinberg CR, Meyer K, Fredriksen A, Ueland PM, Johansen AM, Drevon CA, Jugessur A, Trung TN, Gjessing HK, Vollset SE, Murray JC, Christensen K, Lie RT.
Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.
Genet Epidemiol. 2009 Apr;33(3):247-55.

Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Trung TN, Bille C, Lidral AC, Murray JC.
Genetic determinants of facial clefting: analysis of 357 candidate genes using two national cleft studies from Scandinavia.
PLoS One. 2009;4(4):e5385.

Kimani JW, Yoshiura KI, Shi M, Jugessur A, Moretti-Ferreira D, Christensen K, Murray J.
Search for Genomic Alterations in Monozygotic Twins Discordant for Cleft Lip and/or Palate.
Twin Research and Human Genetics 2009 Okt; 12(5):462-8.

Moreno LM, Mansilla MA, Bullard SA, Cooper ME, Busch TD, Machida J, Johnson MK, Brauer D, Krahn K, Daack-Hirsch S, L'heureux J, Valencia-Ramirez C, Rivera D, López AM, Moreno MA, Hing A, Lammer EJ, Jones M, Christensen K, Lie RT, Jugessur A, Wilcox AJ, Chines P, Pugh E, Doheny K, Arcos-Burgos M, Marazita ML, Murray JC, Lidral AC.
FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate.
Hum Mol Genet. 2009 Dec 15;18(24):4879-96.

Shi M, Mostowska A, Jugessur A, Johnson MK, Mansilla MA, Christensen K, Lie RT, Wilcox AJ, Murray JC.
Identification of microdeletions in candidate genes for cleft lip and/or palate.
Birth Defects Res A Clin Mol Teratol. 2009 Jan;85(1):42-51.

2008

Rahimov F, Marazita ML, Visel A, Cooper ME, Hitchler MJ, Rubini M, Domann FE, Govil M, Christensen K, Bille C, Melbye M, Jugessur A, Lie RT, Wilcox AJ, Fitzpatrick DR, Green ED, Mossey PA, Little J, Steegers-Theunissen RP, Pennacchio LA, Schutte BC, Murray JC.
Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip.
Nat Genet. 2008 Nov;40(11):1341-7.

2007

Bille C, Olsen J, Vach W, Knudsen VK, Olsen SF, Rasmussen K, Murray JC, Andersen A-MN, Christensen K.
Oral clefts and life style factors – a case-cohort study based on prospective Danish data.
European Journal of Epidemiology 2007;22:173-181.

Bille C, Murray JC, Olsen SF.
Folic acid and birth malformations.
British Medical Journal 2007;334:433-434 (editorial).

Kimani JW, Shi M, Daack-Hirsch S, Christensen K, Moretti-Ferreira D, Marazita ML, Field LL, Canady JW, Murray JC.
X-chromosome inactivation patterns in monozygotic twins and sib pairs discordant for nonsyndromic cleft lip and/or palate.
Am J Med Genet A. 2007 Dec 15;143A(24):3267-72.

Shi M, Christensen K, Weinberg CR, Romitti P, Bathum L, Lozada A, Morris RW, Lovett M, Murray JC.
Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants.
Am J Hum Genet. 2007 Jan;80(1):76-90.

Zhu JL, Basso O, Obel C, Bille C, Olsen J.
Infertilitet og medfødte misdannelser.
Ugeskrift for læger 2007 Mar; 169(10):918-20.

2006

Zhu JL, Basso O, Obel C, Bille C, Olsen J.
Infertility, infertility treatment, and congenital malformations: Danish national birth cohort.
British Medical Journal 2006 Sep 30;333(7570):679. 

Avila JR, Jezewski PA, Vieira AR, Orioli IM, Castilla EE, Christensen K, Daack-Hirsch S, Romitti PA, Murray JC.
PVRL1 variants contribute to non-syndromic cleft lip and palate in multiple populations.
American Journal of Medical Genetics Part A 2006; 1;140(23):2562-70.

Warrington A, Vieira AR, Christensen K, Orioli IM, Castilla EE, Romitti PA, Murray JC.
Genetic evidence for the role of loci at 19q13 in cleft lip and palate.
Journal of Medical Genetics 2006;43(6):e26

 

2005

 

Christensen K.
Læbe-ganespalte – arv og miljø.
Kirsten H. Vilting (ed.), 3rd edition. Læbe-ganepalte. En bog for familien. Munksgaards Forlag, pp. 19-28, 2005.

 

Etheredge AJ, Christensen K, Del Junco D, Murray JC, Mitchell LE.
Evaluation of two methods for assessing gene-environment interactions using data from the Danish case-control study of facial clefts.
Birth Defects Research part A: Clinical and Molecular Teratology 2005;73(8):541-6.

 

Bille C, Winther JF, Bautz A. Murray JC, Olsen J, Christensen K.
Cancer risk in persons with oral cleft – a population-based study of 8,093 cases.
American Journal of Epidemiology 2005;161(11):1047-55.

 

Bille C, Knudsen LB, Christensen K.
Changing lifestyles and oral clefts occurrence in Denmark.
Cleft Palate-Craniofacial Journal 2005;42(3):255-59.

 

Bille C, Skytthe A, Vach W, Knudsen LB, Andersen A-MN, Murray JC, Christensen K.
Parent’s age and the risk of oral clefts.
Epidemiology 2005;16(3):311-316.

 

Mansilla MA, Kimani, Mitchell LE, Christensen K. et al.
Discordant MZ twins with cleft lip and palate: a model for identifying genes in complex traits .
Twin Research and Human Genetics 2005;8(1):39-46.

 

Zucchero TM, Cooper ME, Maher BS, et al.
Interferon regulatory factor 6(IRF6) gene variants and the risk of isolated cleft lip or palate.
New England Journal of Medicine 2004;351(8):769-780.

Christensen K, Juel K, Herskind AM, Murray JC.
Long term follow up study of survival associated with cleft lip and palate at birth.
British Medical Journal 2004;328(7453):1405.

1985-2003

Shi M, Caprau D, Romitti P, Christensen K, Murray JC.
Genotype frequencies and linkage disequilibrium in the CEPH human diversity panel for variants in folate pathways genes MTHRF, MTHFD, MTRR, RFC1 and GCP2.
Birth Defects Research 2003;67:545-549.

Jezewski PA, Vieira AR, Nishimura C, Ludwig B, Johnson M, O’Brien SE, Daack-Hirsch S, Schultz RE, Weber A, Nepomucena B, Romitti PA, Christensen K, Orioli IM, Castilla EE, Machida J, Natsume N, Murray JC.
Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate.
Journal of Medical Genetics 2003;40(6):399-407. Pubmed abstract

Mitchell LE, Murray JC, O'Brien S, Christensen K.
Retinoic acid receptor Alpha gene variants, multivitamin use and liver intake as risk factors for oral clefts: A Population-based case-control study in Denmark, 1991-1994.
American Journal of Epidemiology 2003;158:69-76. Pubmed abstract

Jakobsen LP, Mølsted K, Christensen K.
Occurrence of cleft lip and palate in the Faeroe Islands and Greenland from 1950 to 1999.
Cleft Palate-Craniofacial Journal 2003;40(4):426-430. Pubmed abstract

Christensen K.
Methodological issues in epidemiological studies of oral clefts.
Cleft Lip and Palate - from origin to treatment: pp 101-107. Edited by Diego F. Wyszynski. Oxford University Press, 2002.

Christensen K.
Vitamins, Fever and Birth Defects – Consistent Interaction or Persistent Bias?
Epidemiology 2002;13(6):620-621. Pubmed abstract

Christensen K, Mortensen PB.
Facial clefting and psychiatric diseases: A follow-up of the Danish 1936-1987 facial cleft cohort. Cleft Palate-Craniofacial Journal 2002;39(4): 392-396. Pubmed abstract

Mitchell LE, Murray JC, O'Brien S, Christensen K.
Evaluation of two putative susceptibility loci for oral clefts in the Danish population.
American Journal of Epidemiology 2001;153(10):1007-1015. Pubmed abstract

Christensen K.
The 20th Century Danish Facial Cleft Population.
Epidemiological and Genetic - Epidemiological Studies.
University of Southern Denmark, 1999. Pubmed abstract

Basso O, Olsen J, Christensen K.
Recurrence risk of congenital anomalies: the impact of paternal, social and environmental factors. A population-based study in Denmark.
American Journal of Epidemiology 1999;150:598-604. Pubmed abstract

Christensen K.
The 20th Century Danish Facial Cleft Population - Epidemiological and Genetic- Epidemiological Studies.
Cleft Palate-Craniofacial Journal 1999;36:96-104. Pubmed abstract

Christensen K, Olsen J, Nørgaard-Pedersen B, Basso O, Støvring H, Milhollin-Johnson L, Murray JC.
Oral clefts, transforming growth factor alpha gene variants, and maternal smoking. A population based case-control study in Denmark 1991-1994.
American Journal of Epidemiology 1999;149:248-255. Pubmed abstract

Christensen K, Knudsen LB.
Registration of congenital malformations in Denmark.
Danish Medical Bulletin 1998;45:91-94. Pubmed abstract

Mitchell LE, Christensen K.
Evaluation of family history data for Danish twins with nonsyndromic cleft lip with or without cleft palate
[Letter with original data].
American Journal of Medical Genetics 1997;72:120-121.

Christensen K, Schmidt MM, Væth M, Olsen J.
Gentagelsesrisiko for læbe-ganespalte efter partner- eller adresseskift.
[Recurrence risk for CLP after change of partner or address].
Ugeskrift for Læger 1996;158:6103-6106 (invited parallel publication).

Christensen K, Schmidt MM, Væth M, Olsen J.
Absence of an environmental effect on the recurrence of facial-cleft defects.
In Klaus MH (Ed.). Year Book of Neonatal and Perinatal Medicine. Chicago, Mosby 1996 (invited parallel publication). Pubmed abstract

Christensen K, Fogh-Andersen P.
Cleft-Twin Sets in Finland 1948-1987.
The Cleft Palate- Craniofacial Journal 1996;33:530. Pubmed abstract

Brøndum-Nielsen K, Christensen K.
Chromosome 22q11 deletion and other chromosome aberrations in cases with cleft palate, congenital heart defects and/or mental disabilities. A survey based on the Danish facial cleft register.
Clinical Genetics 1996;50: 116-120. Pubmed abstract

Mitchell LE, Christensen K.
Analysis of the recurrence patterns for nonsyndromic cleft lip with or without cleft palate in the families of 3,073 Danish probands.
American Journal of Medical Genetics 1996;61:371-376. Pubmed abstract

Christensen K, Mitchell LE.
Familial recurrence-pattern analysis of nonsyndromic isolated cleft palate - a Danish registry study.
American Journal of Human Genetics 1996;58: 182-190. Pubmed abstract

Christensen K, Schmidt MM, Væth M, Olsen J.
Absence of an environmental effect on the recurrence of facial-cleft defects.
New England Journal of Medicine 1995;333:161-164. Pubmed abstract

Christensen K, Fogh-Andersen P.
Læbe-ganespalte. Arv og miljø [Cleft lip and palate. Inheritance and environment].
In: Vilting K, (ed.). Læbe-ganespalte@ [Cleft lip and palate].
København, Munksgaard 1994:18-29.

Christensen K.
Epidemiology and etiology of cleft lip and/or palate. A genetic-epidemiological study based on 55 Danish birth cohorts with emphasis on selection bias and twin studies.
Odense University, 1994.

Christensen K, Fogh-Andersen P.
Etiological subgroups in non-syndromic isolated cleft palate? A genetic-epidemiological study of 52 Danish birth cohorts.
Clinical Genetics 1994;46:329-335. Pubmed abstract

Christensen K, Fogh-Andersen P.
Isolated cleft palate in Danish multiple births, 1970-1990.
The Cleft Palate-Craniofacial Journal 1993;30:469-474. Pubmed abstract

Christensen K, Fogh-Andersen P.
Cleft lip (+/- cleft palate) in Danish twins, 1970-1990.
American Journalof Medical Genetics 1993;47:910-916. Pubmed abstract

Christensen K, Holm NV, Olsen J, Fogh-Andersen P.
Evaluering af det danske misdannelsesregisters registrering af læbe-ganespalter i perioden 1983-1987.
[Evaluation of the registration of cleft lip and palate in the Danish Register of Malformations in the period 1983-1987].
Ugeskrift for Læger 1992; 154:715-719.

Christensen K, Holm NV, Olsen J, Kock K, Fogh-Andersen P.
Selection bias in genetic- epidemiological studies of cleft lip and palate.
American Journal of Human Genetics 1992; 51:654-659. Pubmed abstract

Christensen, K.
Ophobning af medfødte misdannelser i en fynsk la­nd­kommune?
[Accumulation of congenital malformations in a rural district council in Funen].
Ugeskrift for Læger 1985; 147:3643-3644.

Læbe-Ganespalte Databasen

Register for danske børn født med læbe-ganespalte 1936-2005

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