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Seneste publikationer

Heritability of the Number of Teeth in Middle-Aged and Older Danish Twins.
Kurushima Y, Silventoinen K, Dokkedal U, Skytthe A, Mucci LA, Christensen K, Hjelmborg JVB.
J Dent Res. 2017 Dec;96(13):1513-1517 Pubmed abstract

 

Testing the face shape hypothesis in twins discordant for nonsyndromic orofacial clefting.

Roosenboom J, Indencleef K, Hens G, Peeters H, Christensen K, Marazita ML, Claes P, Leslie EJ, Weinberg SM.
Am J Med Genet A. 2017 Nov;173(11):2886-2892. Pubmed abstract

 

Religiousness and health in Europe.

Ahrenfeldt LJ, Möller S, Andersen-Ranberg K, Vitved AR, Lindahl-Jacobsen R, Hvidt NC.
Eur J Epidemiol. 2017 Oct;32(10):921-929. Pubmed abstract

Biodemography of Aging Determinants of Healthy Life Span and Longevity.

Canudas-Romo V, Aburto JM.
Eur J Popul 2017 Oct; 33(4):611-613. Online version

Aldringsteorier.

Christensen K, Holm E, Henriksen L.
I: Jastrup S og Holm E (red.): Sygepleje til Ældre, Kbh., Munksgaard. 2017: s. 43-52.

Semen Quality as a Predictor of Subsequent Morbidity: A Danish Cohort Study of 4,712 Men With Long-Term Follow-up.
Latif T, Kold Jensen T, Mehlsen J, Holmboe SA, Brinth L, Pors K, Skouby SO, Jørgensen N, Lindahl-Jacobsen R.
Am J Epidemiol. 2017 Oct;186(8):910-917. Pubmed abstract

Using 4+ to grade near-normal muscle strength does not improve agreement.

O'Neill S, Jaszczak SLT, Steffensen AKS, Debrabant B.
Chiropr Man Therap 2017 Oct; 25:28. Pubmed abstract

 

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts.
Silventoinen K, Tan Q, McGue M, Kaprio J et al.
Twin Res Hum Genet. 2017 Oct;20(5):395-405. Pubmed abstract

 

Handling blood cell composition in epigenetic studies on ageing.
Tan Q, Heijmans BT, Hjelmborg JVB, Soerensen M, Christensen K, Christiansen L.
Int J Epidemiol. 2017 Oct 1;46(5):1717-1718.  Pubmed abstract

 

Metabolic risk profiles in diabetes stratified according to age at onset, islet autoimmunity and fasting C-peptide.
Wod M, Yderstræde KB, Halekoh U, Beck-Nielsen H, Højlund K.
Diabetes Res Clin Pract. 2017 Oct 5;134:62-71. Pubmed abstract

 

Genetic and Environmental Influences on Correlations Between Hearing and Cognitive Functions in Middle and Older Chinese Twins.
Xu C, Zhang D, Tian X, Duan H, Wu Y, Pang Z, Li S, Tan Q.
Twin Res Hum Genet. 2017 Oct;20(5):374-379. Pubmed abstract

 

A genome-wide association study of cognitive function in Chinese adult twins.
Xu C, Zhang D, Wu Y, Tian X, Pang Z, Li S, Tan Q.
Biogerontology. 2017 Oct;18(5):811-819. Pubmed abstract

Group-sequential analysis may allow for early trial termination: illustration by an intra-observer repeatability study.

Gerke O, Vilstrup MH, Halekoh U, Hildebrandt MG, Høilund-Carlsen PF.
EJNMMI Research. 2017 Sep; 7(79):1-6. Online version

 

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.
Macé A, Christensen K et al. 
Nat Commun. 2017 Sep;8(1):744. Pubmed abstract

 

Barriers to lifestyle changes for prevention of cardiovascular disease - a survey among 40-60-year old Danes.
Nielsen JB, Leppin A, Gyrd-Hansen DE, Jarbøl DE, Søndergaard J, Larsen PV.
BMC Cardiovasc Disord. 2017 Sep;17(1):245. Pubmed abstract

Genetic susceptibility to bilateral tinnitus in a Swedish twin cohort.
Maas IL, Brüggemann P, Requena T, Bulla J, Edvall NK, Hjelmborg JV, Szczepek AJ, Canlon B, Mazurek B, Lopez-Escamez JA, Cederroth CR.
Genet Med. 2017 Sep;19(9):1007-1012. Pubmed abstract

Effect of a treat-to-target strategy based on methotrexate and intra-articular betamethasone with or without additional cyclosporin on MRI-assessed synovitis, osteitis, tenosynovitis, bone erosion, and joint space narrowing in early rheumatoid arthritis: results from a 2-year randomized double-blind placebo-controlled trial (CIMESTRA).
Møller-Bisgaard S, Ejbjerg BJ, Eshed I, Hørslev-Petersen K, Hetland ML, Jurik AG, Thomsen H, Torfing T, Stengaard-Pedersen K, Junker P, Krogh NS, Lottenburger T, Ellingsen T, Andersen LS, Skjødt H, Svendsen AJ, Tarp U, Hansen IT, Pødenphant J, Pedersen JK, Lindegaard H, Hanson LG, Vestergaard A, Glinatsi D, Østergaard M.
Scand J Rheumatol. 2017 Sep;46(5):335-345. Pubmed abstract

Handgrip strength and its prognostic value for mortality in Moscow, Denmark, and England.
Oksuzyan A, Demakakos P, Shkolnikova M, Thinggaard M, Vaupel JW, Christensen K, Shkolnikov VM.
PLoS One. 2017 Sep;12(9):e0182684. Pubmed abstract

Familial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer.
Graff RE, Möller S, Passarelli MN, Witte JS, Skytthe A, Christensen K, Tan Q, Adami HO, Czene K, Harris JR, Pukkala E, Kaprio J, Giovannucci E, Mucci LA, Hjelmborg JB.
Clin Gastroenterol Hepatol. 2017 Aug;15(8):1256-1264. Pubmed abstract

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis.
Li S, Christiansen L, Christensen K, Kruse TA, Redmond P, Marioni RE, Deary IJ, Tan Q.
Sci Rep. 2017 Aug 15;7(1):8183. Pubmed abstract

How long do centenarians survive? Life expectancy and maximum life span.
Modig K, Andersson T, Vaupel J, Rau R, Ahlbom A.
J Intern Med. 2017 Aug;282(2):156-163. Pubmed abstract

Epigenome-wide association of DNA methylation in whole blood with bone mineral density.
Morris JA, Tsai PC, Joehanes R, Zheng J, Trajanoska K, Soerensen M, Forgetta V, Castillo-Fernandez JE, Frost M, Spector TD, Christensen K, Christiansen L, Rivadeneira F, Tobias JH, Evans DM, Kiel DP, Hsu YH, Richards JB, Bell JT.
J Bone Miner Res. 2017 Aug;32(8):1644-1650. Pubmed abstract

Quantification of multiple elements in dried blood spot samples.
Pedersen L, Andersen-Ranberg K, Hollergaard M, Nybo H.
Clinical Biochemistry. 2017 Aug;50(12):703-709. Pubmed abstract

Family aggregation of cardiovascular disease mortality: a register-based prospective study of pooled Nordic twin cohorts.
Silventoinen K, Hjelmborg J, Möller S, Ripatti S, Skytthe A, Tikkanen E, Pedersen NL, Magnusson PKE, Christensen K, Kaprio J.
Int J Epidemiol. 2017 Aug 1;46(4):1223-1229. Pubmed abstract

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.
Silventoinen K, Jelenkovic A, Sund R, Yokoyama Y, Hur YM, Cozen W, Hwang AE, Mack TM, Honda C, Inui F, Iwatani Y, Watanabe M, Tomizawa R, Pietiläinen KH, Rissanen A, Siribaddana SH, Hotopf M, Sumathipala A, Rijsdijk F, Tan Q, Zhang D, Pang Z, Piirtola M, Aaltonen S, Öncel SY, Aliev F, Rebato E, Hjelmborg JB, Christensen K, Skytthe A, Kyvik KO, Silberg JL, Eaves LJ, Cutler TL, Ordoñana JR, Sánchez-Romera JF, Colodro-Conde L, Song YM, Yang S, Lee K, Franz CE, Kremen WS, Lyons MJ, Busjahn A, Nelson TL, Whitfield KE, Kandler C, Jang KL, Gatz M, Butler DA, Stazi MA, Fagnani C, D'Ippolito C, Duncan GE, Buchwald D, Martin NG, Medland SE, Montgomery GW, Jeong HU, Swan GE, Krasnow R, Magnusson PK, Pedersen NL, Dahl Aslan AK, McAdams TA, Eley TC, Gregory AM, Tynelius P, Baker LA, Tuvblad C, Bayasgalan G, Narandalai D, Spector TD, Mangino M, Lachance G, Burt SA, Klump KL, Harris JR, Brandt I, Nilsen TS, Krueger RF, McGue M, Pahlen S, Corley RP, Huibregtse BM, Bartels M, van Beijsterveldt CE, Willemsen G, Goldberg JH, Rasmussen F, Tarnoki AD, Tarnoki DL, Derom CA, Vlietinck RF, Loos RJ, Hopper JL, Sung J, Maes HH, Turkheimer E, Boomsma DI, Sørensen TI, Kaprio J.
Am J Clin Nutr. 2017 Aug;106(2):457-466. Pubmed abstract

The oldest-old in China - Authors' reply.
Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel JW.
Lancet. 2017 Aug 26;390(10097):847.

Twin-singleton early-life survival in sub-Saharan Africa.
Christensen K, Bjerregaard-Andersen M.
Lancet Glob Health. 2017 Jul;5(7):e636-e637. Pubmed abstract

Oral Clefts and Academic Performance in Adolescence: The Impact of Anesthesia-Related Neurotoxicity, Timing of Surgery, and Type of Oral Clefts.
Clausen NG, Pedersen DA, Pedersen JK, Møller SE, Grosen D, Wehby GL, Christensen K, Hansen TG.
Cleft Palate Craniofac J. 2017 Jul;54(4):371-380. Pubmed abstract

Potential support ratios: Cohort versus period perspectives.
Kjærgaard S, Canudas-Romo V.
Popul Stud (Camb). 2017 Jul;71(2):171-186. Pubmed abstract

Use of Psychotropic Medications and Visits to Psychiatrists and Psychologists among Individuals with Nonsyndromic Oral Clefts: A Population-Based Cohort Study.
Pedersen DA, Hageman I, Wehby GL, Christensen K.
Birth Defects Res. 2017 Jul;109(11):824-835. Pubmed abstract

Limitations and risks of meta-analyses of longevity studies.
Sebastiani P, Bae H, Gurinovich A, Soerensen M, Puca A, Perls TT.
Mech Ageing Dev. 2017 Jul;165(Pt B):139-146. Pubmed abstract

Stem cell divisions per se do not cause cancer.
Wensink MJ, Vaupel JW, Christensen K.
Epidemiology. 2017 Jul;28(4):e35-e37. Pubmed abstract

Persistent social inequality in life expectancy and disability-free life expectancy: Outlook for a differential pension age in Denmark?
Brønnum-Hansen H, Eriksen ML, Andersen-Ranberg K, Jeune B.
Scand J Public Health. 2017 Jun;45(4):459-462. Pubmed abstract

Chromosomal aberrations in monozygotic and dizygotic twins born in Denmark during 1968-2009.
Kroeldrup L, Larsen LA, Fagerberg C, Hertz JM, Christensen K.
Twin Res Hum Genet. 2017 Jun;20(3):216-225.  Pubmed abstract

Generalized Correlation Coefficient for Non-Parametric Analysis of Microarray Time-Course Data.
Tan Q, Thomassen M, Burton M, Mose KF, Andersen KE, Hjelmborg J, Kruse T.
J Integr Bioinform. 2017 Jun;14(2). Pubmed abstract

The null hypothesis of GSEA, and a novel statistical model for competitive gene set analysis.
Debrabant B.
Bioinformatics. 2017 May 1;33(9):1271-1277. Pubmed abstract

Telomere length is longer in women with late maternal age.
Fagan E, Sun F, Bae H, Elo I, Andersen SL, Lee J, Christensen K, Thyagarajan B, Sebastiani P, Perls T, Honig LS, Schupf N; Long Life Family Study.
Menopause. 2017 May;24(5):497-501. Pubmed abstract

Comparison of Late Mortality among Twins versus Singletons with Congenital Heart Defects.
Herskind AM, Larsen LA, Pedersen DA,  Christensen K.
Am J Cardiol. 2017 May 15;119(10):1680-1686. Pubmed abstract

Incidence of chronic persistent rheumatoid arthritis and the impact of smoking.
Svendsen AJ, Junker P, Houen G, Kyvik KO, Nielsen C, Skytthe A, Holst R.
Arthritis Care Res (Hoboken). 2017 May;69(5):616-624. Pubmed abstract

Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts.
Bogl LH, Christensen K, Skytthe A, Hjelmborg J et al.
Biol Sex Differ. 2017 Apr;8:14. eCollection 2017. Pubmed abstract

Telomeres and the natural lifespan limit in humans.
Steenstrup T, Kark JD, Verhulst S, Thinggaard M, Hjelmborg JV, Dalgård C, Kyvik KO, Christiansen L, Mangino M, Spector TD, Petersen I, Kimura M, Benetos A, Labat C, Sinnreich R, Hwang SJ, Levy D, Hunt SC, Fitzpatrick AL, Chen W, Berenson GS, Barbieri M, Paolisso G, Gadalla SM, Savage SA, Christensen K, Yashin AI, Arbeev KG, Aviv A.
Aging (Albany NY). 2017 Apr;9(4):1130-1142. Pubmed abstract

Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study.
Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel JW.
Lancet. 2017 Apr;389(10079):1619-1629. Pubmed abstract

The association between depression and mortality - a comparison of survey- and register-based measures of depression.
Christensen GT, Maartensson S, Osler M.
J Affect Disord. 2017 Mar;210:111-4.  Pubmed abstract

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women.
Li S, Zhu D, Duan H, Ren A, Glintborg D, Andersen M, Skov V, Thomassen M, Kruse T, Tan Q.
Oncotarget. 2016 Mar;8(13):20656-20666. Pubmed abstract

Best Practice Life Expectancy: An Extreme value Approach.
Medford A.
Dem Res 2017 Mar;36(34):989-1014. Online version

Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years.
Sandahl K, Nielsen LB, Svensson J, Johannesen J, Pociot F, Mortensen HB, Hougaard P, Broe R, Rasmussen ML, Grauslund J, Peto T, Olsen BS.
Diabet Med. 2017 Mar;34(3):380-6. Pubmed abstract

Early-life mortality risks in opposite-sex and same-sex twins: a Danish cohort study of the twin testosterone transfer hypothesis.
Ahrenfeldt LJ, Larsen LA, Lindahl-Jacobsen R, Skytthe A, Hjelmborg JV, Möller S, Christensen K.
Ann Epidemiol. 2017 Feb;27(2):115-120.e2. Pubmed abstract

Efficient detection of differentially methylated regions using DiMmeR.
Almeida D, Skov I, Silva A, Vandin F, Tan Q, Röttger R, Baumbach J.
Bioinformatics. 2017 Feb 15;33(4):549-551. Pubmed abstract

Mortality changes in industrialized societies: past, present and future.
Marie-Pier Bergeron Boucher.
Ph.d. afhandling. 2017 Feb; University of Southern Denmark, MaxO.

Mexico's epidemic of violence and its public health significance on average length of life.
Canudas-Romo V, Aburto JM, García-Guerrero VM, Beltrán-Sánchez H.
J Epidemiol Community Health. 2017 Feb;71(2):188-193. Pubmed abstract

Facets of Subjective Health From Early Adulthood to Old Age.
Franz CE, Finkel D, Panizzon MS, Spoon K, Christensen K, Gatz M, Kremen WS, Krueger R, Neiderhiser J, Reynolds C, Pedersen NL; IGEMS consortium.
J Aging Health. 2017 Feb;29(1):149-171.  Pubmed abstract

The Efficacy of Assisted Reproduction in Women with Inflammatory Bowel Disease and the Impact of Surgery-A Nationwide Cohort Study.
Friedman S, Larsen PV, Fedder J, Nørgård BM.
Inflamm Bowel Dis. 2017 Feb;23(2):208-217. Pubmed abstract

Efficient Management of High-Throughput Screening Libraries with SAVANAH.
List M, Elnegaard MP, Schmidt S, Christiansen H, Tan Q, Mollenhauer J, Baumbach J.
J Biomol Screen. 2017 Feb;22(2):196-202. Pubmed abstract

Disparities in multimorbidity across Europe - Findings from the SHARE Survey
Nielsen CR, Halling A, Andersen-Ranberg K.
Eur Ger. 2017 Feb;8(1):16-21.

Visualizing compositional data on the Lexis surface.
Schöley J, Willekens F.
Dem Res. 2017 Feb;35(21):627-658.

Drug use among complete responders, partial responders and non-responders in a longitudinal survey of nonagenarians: analysis of prescription register data.
Wastesson JW, Rasmussen L, Oksuzyan A, Hallas J, Christensen K, Pottegård A.
Pharmacoepidemiol Drug Saf. 2017 Feb;26(2):152-161. Pubmed abstract

Midlife Cognitive Ability, Education, and Tooth Loss in Older Danes.
Bachkati KH, Mortensen EL, Brønnum-Hansen H, Holm-Pedersen P.
J Am Geriatr Soc. 2017 Jan;65(1):194-9. Pubmed abstract

Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.
Bousquet J,  Andersen-Ranberg K et al.
J Nutr Health Aging. 2017 Jan;21(1):92-104. Pubmed abstract

The influence of familial factors on the intelligence-mortality association: A twin approach

Christensen GT, Osler M, Madsen M, McGue M, Mortensen EL, Christensen K.
Intelligence. 2017;64:60-66.

 

Exploring Subclinical Phenotypic Features in Twin Pairs Discordant for Cleft Lip and Palate.
Leslie EJ, Carlson JC, Cooper ME, Christensen K, Weinberg SM, Marazita ML.
Cleft Palate Craniofac J. 2017 Jan;54(1):90-93. Pubmed abstract

Investigation of the 5q33.3 longevity locus and age-related phenotypes.
Nygaard M, Thinggaard M, Christensen K, Christiansen L.
Aging (Albany NY). 2017 Jan 13;9(1):247-255. Pubmed abstract

Investigating heredity in cutaneous T-cell lymphoma in a unique cohort of Danish twins.
Odum N, Lindahl L, Wod M, Krejsgaard T, Skytthe A, Woetmann A, Iversen L, Christensen K.
Blood Cancer Journal 2017 Jan;7(1):e517.

The Survival of Spouses Marrying Into Longevity-Enriched Families.
Pedersen JK, Elo IT, Schupf N, Perls TT, Stallard E, Yashin AI, Christensen K.
J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):109-114. Pubmed abstract

Disease-Concordant Twins Empower Genetic Association Studies.
Tan Q, Li W, Vandin F.
Ann Hum Genet. 2017 Jan;81(1):20-26. Pubmed abstract

Changes in Drug Use and Polypharmacy After the Age of 90: A Longitudinal Study of the Danish 1905 Cohort.
Wastesson JW, Oksuzyan A, von Bornemann Hjelmborg J, Christensen K.
J Am Geriatr Soc. 2017 Jan;65(1):160-164. Pubmed abstract

The Rarity of Survival to Old Age Does Not Drive the Evolution of Senescence.
Wensink MJ, Caswell H, Baudisch A.
Evol Biol. 2017;44(1):5-10. Pubmed abstract

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