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Publikationsliste: Danske 100 årige

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Improvement in Activities of Daily Living among Danish Centenarians?

Rasmussen SH, Thinggaard M, Højgaard MB, Jeune B, Christensen K, Andersen-Ranberg K.
J Gerontol A Biol Sci Med Sci. 2018 Jul;73(8):1125-1131. Pubmed abstract

Cohort profile: The 1895, 1905, 1910 and 1915 Danish Birth Cohort Studies 

Secular trends in the health and functioning in the very old 
Rasmussen SH, Andersen-Ranberg K, Thinggaard M, Jeune B, Skytthe A, Christiansen L, Vaupel JW, McGue M, Christensen K.

Int J Epidemiol. 2017 Dec;46(6):1746-1746j. Pubmed abstract

Changes in Drug Use and Polypharmacy After the Age of 90 

A Longitudinal Study of the Danish 1905 Cohort

Wastesson JW, Oksuzyan A, von Bornemann Hjelmborg J, Christensen K.

J Am Geriatr Soc. 2017 Jan;65(1):160-164. Pubmed abstract
 

Drug use among complete responders, partial responders and non-responders in a longitudinal survey of nonagenarians

Analysis of prescription register data

Wastesson JW, Rasmussen L, Oksuzyan A, Hallas J, Christensen K, Pottegård A.

Pharmacoepidemiol Drug Saf. 2017 Feb;26(2):152-161. Pubmed abstract

Survival prognosis in very old adults

Thinggaard M, McGue M, Jeune B, Osler M, Vaupel JW, Christensen K.
J Am Geriatr Soc 2016;64:81-88. Pubmed abstract

Health and function assessments in two adjacent Danish birth cohorts of centenarians 

Impact of design and methodology

Vestergaard S, Andersen-Ranberg K, Skytthe A, Christensen K, Robine JM, Jeune B.
Eur J Ageing
2016;13:15-23. Pubmed abstract

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The Danish Centenarian Program: Cardiovascular diseases in Danish Centenarians.
Andersen-Ranberg K, Christensen K, Jeune B.
Eur Geriatr Med. 2014 Sep;5:Suppl 1, p.S15.

Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals
Nygaard M, Lindahl-Jacobsen R, Soerensen M et al.
Exp Gerontol
2014;57:41-46. Pubmed abstract

Cardiovascular diseases are largely underreported in Danish centenarians.
Andersen-Ranberg K, Fjederholt KT, Madzak A, Nybo M, Jeune B.
Age Ageing
2013;42:249-53. Pubmed abstract

Optimism and survival: does an optimistic Outlook predict better survival at advanced ages? A twelve-year follow-up of Danish nonagenarians.
Engberg H, Jeune B, Andersen-Ranberg K, Martinussen T, Vaupel JW, Christensen K.
Aging Clin Exp Res 2013;25:517-25. Pubmed abstract

Centenarians today: New insights on selection from the 5-COOP study.
Robine JM, Cheung SL, Saito Y, Jeune B, Parker MG, Herrmann FR.
Curr Gerontol Geriatric Res 2010;2010:120354. Pubmed abstract

Is the relationship between BMI and mortality increasingly U-shaped with advancing age? A 10-year follow-up of persons aged 70-95 years.
Thinggaard M, Jacobsen R, Jeune B, Martinussen T, Christensen K.
J Gerontol A Biol Sci Med 2010;65:526-31. Pubmed abstract

Ageing populations: the challenges ahead.
Christensen K, Doblhammer G, Rau R, Vaupel JW.
Lancet. 2009;374:1196-208. Pubmed abstract

Centenarians - a useful model for healthy aging?
A 29-year follow-up of hospitalizations among 40,000 Danes born in 1905.
Engberg H, Oksuzyan A, Jeune B, Vaupel JW, Christensen K.
Aging cell 2009;8:270-76. Pubmed abstract
 

Udgivelser 1996-2008:

  1. Cardiovascular diseases are largely underreported in Danish centenarians
    Andersen-Ranberg K, Fjederholt KT, Madzak A, Nybo M, Jeune B.
    Age Ageing. 2013 Mar;42(2):249-53. Pubmed abstract
     
  2. Centenarians - a useful model for healthy aging? A 29-year follow-up of hospitalizations among 40,000 Danes born in 1905
    Engberg H, Oksuzyan A, Jeune B, Vaupel JW, Christensen K.
    Aging Cell. 2009 Jun;8(3):270-6. Pubmed abstract
     
  3. Improving activities of daily living in danish centenarians--but only in women: a comparative study of two birth cohorts born in 1895 and 1905
    Engberg H, Christensen K, Andersen-Ranberg K, Vaupel JW, Jeune B.
    J Gerontol A Biol Sci Med Sci. 2008 Nov;63(11):1186-92. Pubmed abstract
     
  4. Cohort changes in cognitive function among Danish centenarians. A comparative study of 2 birth cohorts born in 1895 and 1905
    Engberg H, Christensen K, Andersen-Ranberg K, Jeune B.
    Dement Geriatr Cogn Disord. 2008;26(2):153-60. Pubmed abstract
     
  5. Pain in the back and neck are with us until the end: A nationwide interview-based survey of Danish 100-year-olds
    Hartvigsen J, Christensen K.
    Spine. 2008 Apr;33(8):909-13. Pubmed abstract
      
  6. Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm
    Kimura M, Cherkas LF, Kato BS, Demissie S, Hjelmborg JB, Brimacombe M, Cupples A, Hunkin JL, Gardner JP, Lu X, Cao X, Sastrasinh M, Province MA, Hunt SC, Christensen K, Levy D, Spector TD, Aviv A.
    PLoS Genet. 2008 Feb;4(2):e37. Pubmed abstract
      
  7. Telomere length and mortality: A study of leukocytes in elderly Danish twins
    Kimura M, Hjelmborg JV, Gardner JP, Bathum L, Brimacombe M, Lu X, Christiansen L, Vaupel JW, Aviv A, Christensen K.
    Am J Epidemiol. 2008 Apr 1;167(7):799-806. Pubmed abstract
      
  8. Evidence for the association of the S100beta gene with low cognitive performance and dementia in the elderly
    Lambert JC, Ferreira S, Gussekloo J, Christiansen L, Brysbaert G, Slagboom E, Cottel D, Petit T, Hauw JJ, DeKosky ST, Richard F, Berr C, Lendon C, Kamboh MI, Mann D, Christensen K, Westendorp R, Amouyel P.
    Mol Psychiatry. 2007 Sep;12(9):870-80. Pubmed abstract
      
  9. Social activity and healthy aging: a study of aging Danish twins
    McGue M, Christensen K. 
    Twin Res Hum Genet. 2007 Apr;10(2):255-65. Pubmed abstract
      
  10. Genetics of healthy aging in Europe: The EU-integrated project GEHA (GEnetics of Healthy Aging)
    Franceschi C, Bezrukov V, Blanché H, Bolund L, Christensen K, de Benedictis G, Deiana L, Gonos E, Hervonen A, Yang H, Jeune B, Kirkwood TB, Kristensen P, Leon A, Pelicci PG, Peltonen L, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Sikora E, Slagboom PE, Spazzafumo L, Stazi MA, Toussaint O, Vaupel JW.
    Ann NY Acad Sci. 2007 Apr;1100:21-45. Review. Pubmed abstract
      
  11. Self-rated health and age: A cross-sectional and longitudinal study of 11,000 Danes aged 45-102
    Andersen FK, Christensen K, Frederiksen H. 
    Scand J Public Health. 2007;35(2):164-71. Pubmed abstract
      
  12. Bathum L, von Bornemann Hjelmborg J, Christiansen L, McGue M, Jeune B, Christensen K.
    Methylenetetrahydrofolate reductase 677C>T and methionine synthase 2756A>G mutations: no impact on survival, cognitive functioning, or cognitive decline in nonagenarians.
    J Gerontol A Biol Sci Med Sci. 2007 Feb;62(2):196-201. Pubmed abstract
      
  13. Active lifestyle protects against incident low back pain in seniors: a population-based 2-year prospective study of 1387 Danish twins aged 70-100 years
    Hartvigsen J, Christensen K.
    Spine 2007 Jan;32(1):76-81. Pubmed abstract
      
  14. Retrospective analysis of main and interaction effects in genetic association studies of human complex traits
    Tan Q, Christiansen L, Brasch-Andersen C, Zhao JH, Li S, Kruse TA, Christensen K.
    BMC Genetics 2007 Oct 16; 8:70. Pubmed abstract
      
  15. Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population
    Christiansen L, Tan Q, Iachina M, Bathum L, Kruse TA, McGue M, Christensen K.
    Biol Psychiatry. 2007 Jan 15;61(2):223-30. Pubmed abstract
      
  16. The pattern of chromosome-specific variations in telomere length in humans shows signs of heritability and is maintained through life
    Graakjaer J, Londono-Vallejo JA, Christensen K, Kølvraa S. 
    Ann NY Acad Sci. 2006 May;1067:311-6. Pubmed abstract
      
  17. Heat-shock protein 70 genes and human longevity: A view from Denmark
    Singh R, Kølvraa S, Bross P, Christensen K, Gregersen N, Tan Q, Jensen UB, Eiberg H, Rattan SI.
    Ann N Y Acad Sci. 2006 May;1067:301-8. Pubmed abstract
      
  18. Physical and mental function and incident low back pain in seniors: a population-based two-year prospective study of 1387 Danish Twins aged 70 to 100 years
    Hartvigsen J, Frederiksen H, Christensen K.
    Spine. 2006 Jun 15;31(14):1628-32. Pubmed abstract
      
  19. A longitudinal study of the effect of GSTT1 and GSTM1 gene copy number on survival
    Christiansen L, Brasch-Andersen C, Bathum L, Kruse TA, Christensen K.
    Mech Ageing Dev. 2006 Jul;127(7):597-9. Pubmed abstract
      
  20. No association between telomere length and survival among the elderly and oldest old
    Bischoff C, Petersen HC, Graakjaer J, Andersen-Ranberg K, Vaupel JW, Bohr VA, Kølvraa S, Christensen K.
    Epidemiology. 2006 Mar;17(2):190-4. Pubmed abstract
      
  21. Apolipoprotein E genotypes: relationship to cognitive functioning, cognitive decline, and survival in nonagenarians
    Bathum L, Christiansen L, Jeune B, Vaupel J, McGue M, Christensen K.
    JAGS 2006 Apr;54(4):654-8. Pubmed abstract
      
  22. Genetic association analysis of human longevity in cohort studies of elderly subjects: an example of the PON1 gene in the Danish 1905 birth cohort
    Tan Q, Christiansen L, Bathum L, Li S, Kruse TA, Christensen K.
    Genetics 2006 Mar;172(3):1821-8. Pubmed abstract
      
  23. Design and analysis in genetic studies of human ageing and longevity
    Tan Q, Kruse TA, Christensen K. 
    Ageing Res Rev. 2006 Nov; 5(4): 371-87. Pubmed abstract
      
  24. The quest for genetic determinants of human longevity: Challenges and insights
    Christensen K, Johnson TE, Vaupel JW.
    Nat Rev Genet. 2006 Jun;7(6):436-48. Pubmed abstract
      
  25. Genetic influence on human lifespan and longevity
    Hjelmborg JvB, Iachine I, Skytthe A, Vaupel JW, McGue M, Koskenvuo M, Kaprio J, Pedersen NL, Christensen K.
    Hum Genet. 2006 Apr;119(3):312-21. Pubmed abstract
      
  26. Age trajectories of grip strength: Cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102
    Frederiksen H, Hjelmborg J, Mortensen J, McGue M, Vaupel JW, Christensen K.
    Ann Epidemiol. 2006 Jul;16(7):554-62. Pubmed abstract
      
  27. Genetic influence on thrombotic risk markers in the elderly - A Danish twin study
    Bladbjerg EM, de Maat MP, Christensen K, Bathum L, Jespersen J, Hjelmborg J.
    J Thromb Haemost. 2006 Mar;4(3):599-607. Pubmed abstract
      
  28. Handgrip strength among nonagenarians and centenarians in three European regions
    Jeune B, Skytthe A, Cournil A, Greco V, Gampe J, Berardelli M, Andersen-Ranberg K, Passarino G, Debenedictis G, Robine JM.
    J Gerontol A Biol Sci Med Sci. 2006 Jul;61(7):707-12. Pubmed abstract
      
  29. No evidence for an association between extreme longevity and microsomal transfer protein polymorphisms in a longitudinal study of 1651 nonagenarians
    Bathum L, Christiansen L, Tan Q, Vaupel J, Jeune B, Christensen K. 
    Eur J Hum Genet. 2005 Oct;13(10):1154-8. Pubmed abstract
      
  30. Small effects of genetic factors on neck pain in old age. A study of 2,108 Danish twins 70 years of age and older
    Hartvigsen J, Pedersen H C, Frederiksen H, Christensen K.
    Spine 2005 Jan 15;30(2):206-8. Pubmed abstract
      
  31. The longevity gender gap: Are telomeres the explanation?
    Aviv A, Shay J, Christensen K, Wright W.
    Sci Aging Knowledge Environ. 2005 Jun 8;2005(23):pe16. Review. Pubmed abstract
      
  32. Estimating haplotype relative risks on human survival in population-based association studies
    Tan Q, Christiansen L, Bathum L, Zhao JH, Yashin AI, Vaupel JW, Christensen K, Kruse TA.
    Human Heredity 2005;59(2):88-97. Pubmed abstract
      
  33. Telomere length among the elderly and oldest-old
    Bischoff C, Graakjaer J, Petersen HC, Jeune B, Bohr VA, Koelvraa S, Christensen K.
    Twin Res Hum Genet. 2005 Oct;8(5):425-32. Pubmed abstract
      
  34. The heritability of telomere length among the elderly and oldest-old
    Bischoff C, Graakjaer J, Petersen HC, Hjelmborg JvB, Vaupel JW, Bohr VA, Koelvraa S, Christensen K.
    Twin Res Hum Genet. 2005 Oct;8(5):433-9. Pubmed abstract
      
  35. Rohr G, Stovring H, Christensen K, Gaist D, Nybo H, Kragstrup J.
    Characteristics of middle-aged and elderly women with urinary incontinence.
    Scand J Prim Health Care 2005 Dec;23(4):203-8. Pubmed abstract
      
  36. Tan Q, Christiansen L, Christensen K, Kruse TA, Bathum L.
    Apolipoprotein E genotype frequency patterns in aged Danes as revealed by logistic regression models.
    Eur J Epidemiol. 2004;19(7):651-6. Pubmed abstract
      
  37. Christiansen L, Petersen HC, Bathum L, Frederiksen H, McGue M, Christensen K.
    The catalase -262C/T promoter polymorphism and aging phenotypes.
    J Gerontol A Biol Sci Med Sci. 2004 Sep;59(9):B886-9. Pubmed abstract
      
  38. Christiansen L, Bathum L. Frederiksen H, Christensen K.
    Paraoxonase 1 polymorphisms and survival.
    Eur J Hum Genet. 2004 Oct;12(10):843-7. Pubmed abstract
      
  39. Andersen-Ranberg K, Høier-Madsen M, Wiik A, Jeune B, Hegedus L.
    High prevalence of autoantibodies among Danish centenarians.
    Clin Exp Immunol. 2004 Oct;138(1):158-63. Pubmed abstract
      
  40. Bruunsgaard H, Benfield TL, Andersen-Ranberg K, Hjelmborg JB, Pedersen AN, Schroll M, Pedersen BK, Jeune B.
    The tumor necrosis factor alpha -308G>A polymorphism is associated with dementia in the oldest old.
    J Am Geriatr Soc. 2004 Aug;52(8):1361-6. Pubmed abstract
      
  41. Christiansen L, Bathum L, Andersen-Ranberg K, Jeune B, Christensen K.
    Modest implication of interleukin-6 promoter polymorphisms in longevity.
    Mech Ageing Dev. 2004 May;125(5):391-5. Pubmed abstract
      
  42. Bruunsgaard H, Andersen-Ranberg K, Hjelmborg JB, Pedersen BK, Jeune B.
    Elevated levels of tumor necrosis factor alpha and mortality in centenarians.
    Am J Med. 2003 Sep;115(4):278-83. Pubmed abstract
      
  43. Nybo H, Petersen HC, Gaist D, Jeune B, Andersen K, McGue M, Vaupel JW, Christensen K.
    Predictors of mortality in 2,249 nonagenarians - the Danish 1905-Cohort Survey.
    J Am Geriatr Soc. 2003 Oct;51(10):1365-73. Pubmed abstract
      
  44. Sandmand M, Bruunsgaard H, Kemp K, Andersen-Ranberg K, Schroll M, Jeune B.
    High circulating levels of tumor necrosis factor-alpha in centenarians are not associated with increased production in T lymphocytes.
    Gerontology. 2003 May-Jun;49(3):155-60. Pubmed abstract
      
  45. Bruunsgaard H, Østergaard L, Andersen-Ranberg K, Jeune B, Pedersen BK.
    Proinflammatory cytokines, antibodies to Chlamydia pneumoniae and age-associated diseases in Danish centenarians: Is there a link?
    Scand J Infect Dis. 2002;34(7):493-9. Pubmed abstract
      
  46. Tan Q, Yashin AI, Bladbjerg EM, de Maat MP, Andersen-Ranberg K, Jeune B, Christensen K, Vaupel JW.
    A case-only approach for assessing gene by sex interaction in human longevity.
    J Gerontol A Biol Sci Med Sci. 2002 Apr;57(4):B129-33. Pubmed abstract
      
  47. Frederiksen H, McGue M, Jeune B, Gaist D, Nybo H, Skytthe A, Vaupel JW, Christensen K.
    Do children of long-lived parents age more successfully?
    Epidemiology 2002 May;13:334-9. Pubmed abstract
      
  48. Frederiksen H, McGue M, Jeune B, Gaist D, Nybo H, Skytthe AE, Vaupel JW, Christensen K.
    Har børn af længelevende forældre en bedre alderdom?
    [Do children of long-lived parents age more successfully?] 
    Ugeskr Laeger. 2002 Oct 21; 164(43):5027-32. (invited parallel publication)
      
  49. Andersen K, Nybo H, Gaist D, Petersen HC, McGue M, Jeune B, Vaupel JW, Christensen K.
    Cognitive impairment and mortality among nonagenarians: The Danish 1905 cohort survey.
    Dement Geriatr Cogn Disord. 2002;13(3):156-63. Pubmed abstract
      
  50. Rosholm JU, Nybo H, Andersen Ranberg K, Himmelstrup B, Skjelbo E, Christensen K, Gram LF.
    Hyponatraemia in very old nonhospitalised people: Association with drug use.
    Drugs Aging. 2002;19(9):685-93. Pubmed abstract
      
  51. Bathum L, Christiansen L, Nybo H, Ranberg KA, Gaist D, Jeune B, Petersen NE, Vaupel J, Christensen K.
    Association of mutations in the hemochromatosis gene with shorter life expectancy.
    Arch Intern Med. 2001 Nov 12;161(20):2441-4. Pubmed abstract
     
  52. Tan Q, Yashin AI, Bladbjerg EM, de Maat MP, Andersen-Ranberg K, Jeune B, Christensen K, Vaupel JW.
    Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity.
    Exp Gerontol. 2001 Aug;36(8):1303-15. Pubmed abstract
     
  53. Varcasia O, Garasto S, Rizza T, Andersen-Ranberg K, Jeune B, Bathum L, Andreev K, Tan Q, Yashin AI, Bonafè M, Franceschi C, De Benedictis G.
    Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus.
    Ann Hum Genet. 2001 Jul;65(Pt 4):371-6. Pubmed abstract
      
  54. Andersen-Ranberg K, Schroll M, Jeune B.
    Healthy centenarians do not exist, but autonomous centenarians do: A population-based study of morbidity among Danish centenarians.
    J Am Geriatr Soc. 2001 Jul;49(7):900-8. Pubmed abstract
      
  55. Andersen-Ranberg K, Vasegaard L, Jeune B.
    Dementia is not inevitable: A population-based study of Danish centenarians.
    J Gerontol B Psychol Sci Soc Sci. 2001 May;56(3):P152-9. Pubmed abstract
      
  56. Nybo H, Gaist D, Jeune B, McGue M, Vaupel JW, Christensen K.
    Functional status and self-rated health in 2,262 nonagenarians: The Danish 1905 Cohort Survey.
    J Am Geriatr Soc. 2001 May;49(5):601-9. Pubmed abstract
      
  57. Nybo H, Gaist D, Jeune B, Bathum L, McGue M, Vaupel JW, Christensen K.
    The Danish 1905 cohort: A genetic-epidemiological nationwide survey.
    J Aging Health. 2001 Feb;13(1):32-46. Pubmed abstract
      
  58. Christensen K, Kristiansen M, Hagen-Larsen H, Skytthe A, Bathum L, Jeune B, Andersen-Ranberg K, Vaupel JW, Orstavik KH.
    X-linked genetic factors regulate hematopoietic stem-cell kinetics in females.
    Blood. 2000 Apr;95(7):2449-51. Pubmed abstract
      
  59. Hvad kan vi lære af hundredårige?
    Jeune B, Andersen-Ranberg K.
    [What can be learned from centenarians?]
    Ugeskr Laeger. 1999;161(46):6321-5. Danish.
      
  60. Thyroid function, morphology and prevalence of thyroid disease in a population-based study of Danish centenarians
    Andersen-Ranberg K, Jeune B, Høier-Madsen M, Hegedüs L. 
    J Am Geriatr Soc. 1999 Oct;47(10):1238-43. Pubmed abstract
      
  61. Longevity is independent of common variations in genes associated with cardiovascular risk
    Bladbjerg EM, Andersen-Ranberg K, de Maat MP, Kristensen SR, Jeune B, Gram J, Jespersen J. 
    Thromb Haemost. 1999 Sep;82(3):1100-5. Pubmed abstract
      
  62. A high plasma concentration of TNF-alpha is associated with dementia in centenarians
    Bruunsgaard H, Andersen-Ranberg K, Jeune B, Pedersen AN, Skinhøj P, Pedersen BK. 
    J Gerontol A Biol Sci Med Sci. 1999 Jul;54(7):M357-64. Pubmed abstract
      
  63. Declining physical abilities with age: a cross-sectional study of older twins and centenarians in Denmark
    Andersen-Ranberg K, Christensen K, Jeune B, Skytthe A, Vasegaard L, Vaupel JW.
    Age Ageing. 1999 Jul;28(4):373-7. Pubmed abstract
      
  64. Factor V Leiden and venous thrombosis in Danish centenarians
    Kristensen SR, Andersen-Ranberg K, Bathum L, Jeune B.
    Thromb Haemost. 1998 Nov;80(5):860-1. Pubmed abstract
      
  65. Low activity of superoxide dismutase and high activity of glutathione reductase in erythrocytes from centenarians
    Andersen HR, Jeune B, Nybo H, Nielsen JB, Andersen-Ranberg K, Grandjean P.
    Age Ageing. 1998 Sep;27(5):643-8. Pubmed abstract
      
  66. Increased plasma concentration of serum amyloid P component in centenarians with impaired cognitive performance
    Nybo M, Olsen H, Jeune B, Andersen-Ranberg K, Holm Nielsen E, Svehag SE.
    Dement Geriatr Cogn Disord. 1998 May-Jun;9(3):126-9. Pubmed abstract
      
  67. Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevity. Role of CYP2D6 and CYP2C19 in longevity
    Bathum L, Andersen-Ranberg K, Boldsen J, Brøsen K, Jeune B. 
    Eur J Clin Pharmacol. 1998 Jul;54(5):427-30. Pubmed abstract
      
  68. Hundredårige på Fyn
    Olsen H, Jeune B, Andersen-Ranberg K.
    [Centenarians in the county of Funen. Morbidity and functional capacity].
    Ugeskr Laeger. 1996;158(51):7397-401. Danish. Pubmed abstract

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