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Owens Group

 
  Trevor Owens
Professor, Head of Research
Tlf.: 6550 3951 / 6011 3951
Email: towens@health.sdu.dk
For CV, list of publications, publicity, international network etc. see profil on portal.findresearcher.sdu.dk

   

Research interests

We study pathogenic mechanisms of inflammatory diseases of the central nervous system (CNS), such as multiple sclerosis and neuromyelitis optica. Such mechanisms are often relevant to degenerative diseases such as Alzheimers disease. 

We study interactions between the immune system and glial cells of the nervous system, both those that lead to pathology as well as with regulatory and protective outcomes. We are particularly interested in translating clinical observations to experimental analyses. Our goal is to understand how innate and adaptive immune cells and mediators contribute to neurological disease.

Methods and techniques 

We mainly focus to mouse models and we use histological, flow cytometric, molecular and tissue culture methods to evaluate immuno- and neuropathogenesis in genetically-modified mice.

Collaborations within SDU 

Bente Finsen and Kate Lykke Lambertsen (NB IMM) – Microglia a key to brain rejuvenation
Ulrike Muscha Steckelings (CVR IMM) – Protective role for Angiotensin Type 2 Receptor in neuroinflammation
Martin Wirenfeldt Nielsen (Pathology, OUH) – Pathology of MS-protective fetal and maternal tissue
Mads Thomassen (Clinical Genomics, OUH) – Transcriptional analysis of glial cells
Jesper Grud Skat Madsen (Biochemistry Molecular Biology) - Analysis of single cell transcriptomics
Grith Lykke Sørensen (CVR IMM) – Novel biomarkers for NMOSD

Support received from 

Scleroseforeningen
Independent Research Fund Denmark
Lundbeckfonden
EU Marie-Sklodowska Curie Actions

Information for students

We welcome applications from motivated and interested students, at all levels.