Green Chemistry: Biomimetic Catalysts for Selective C-H Oxidation

Vejleder: Christine McKenzie

Projektbeskrivelse

Inspired by insight into Nature's metalloenzymes we aim at the discovery of considerably simpler and more robust transition metal complexes which mimic their reactivity in catalysing atom economic reactions. This research impacts into areas as diverse as environmentally benign and renewable energy production, water remediation and greener methods for drug synthesis. Specific projects are:

  • Improving the atom economy of a recently discovered highly selective and efficient oxidation catalysis by developing a new technique for terminal oxidant recycling, see figure.[1,2]

     

  • The use of O2 in air as the terminal oxidant in the selective oxidation of organic substrates.[3]

 

[1] A. Lennartson, C. J. McKenzie, A Fe(III)iodosylbenzene complex – Masked Fe(V)OAngew. Chemie, Int. Ed. 2012, 51, 6767-6770.

[2] D. P. de Sousa, C. Wegeberg, M. S. Vad, S. Mørup, C. Frandsen, W. A. Donald, and C. J. McKenzie Halogen-Bonding Assisted Iodosylbenzene Activation by a Homogenous Iron Catalyst, Chemistry, Eur. J. 2016, 22, 3521–3890.

[3] C. Deville, S. K. Padamati, Jonas Sundberg, V. McKee, W. R. Browne and C. J. McKenzie, O2 Activation and Double C-H Oxidation by a Mononuclear Manganese(II) Complex, Angew., Chem., Int. Ed. 2016, 55, 545-549.