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Forskningspublikationer

Et ambitiøst tiår! - Ideer fra området medicinsk humaniora.
Hvordan kan mere borgerinddragelse i udviklingen af nye sundhedsløsninger og endnu bedre sundhedskommunikation skabe større lighed i sundhedssektoren. Humanistisk forskning er en vigtig brik, når der skal findes nye løsninger på store udfordringer.
Mai AM. 
Dansk Magisterforening, jan. 2021. DM: Kronik


2020

Er ældres sundhed og trivsel virkelig stagneret igennem de sidste ti år?
Christensen K, Kyvsgaard I, Christensen AI, Jeune B.
Ugeskrift for Laeger.
2020;182(12).

Mechanisms underlying familial aggregation of exceptional health and survival: a three-generation cohort study.
Christensen K, Wojczynski MK, Pedersen JK, Larsen LA, Klojgaard S, Skytthe A, McGue M, Vaupel JW, Province MA.
Aging Cell 2020;19(10):e13228.

Physical robustness and resilience among long-lived female siblings: a comparison with sporadic long-livers.
Galvin A, Ukraintseva S, Arbeev K, Feitosa M, Christensen K.
Aging (Albany NY) 2020;12(14):15157-15168.

“I simply don't know, because I don't know which drugs I get”: Perspectives on deprescribing among older adults with limited life expectancy and their relatives.
Graabæk T, Lundby C, Ryg J, Søndergaard J, Pottegård A, Nielsen DS.
Basic & Clinical Pharmacology & Toxicology 2020;128 (1), 115-127

Litteraturgerontologi. Dansk ældrelitteratur i et brugsperspektiv.
Lund, N.F., Kristensen, M.M., Folker, A. P. & Simonsen, P.
Gerontologi 2020 36, 2 p. 4-8

Eksempel. Samtidig dansk/skandinavisk ældrelitteratur,
Lund, N.F. & Simonsen, P.
Gerontologi Oct. 2020,, 36,2, p. 31

Happy ends?
in:
Ældrevelfærd – samtidsperspektiver på aldring og det gode liv (ed. Emiliussen & Klausen), Aalborg Lund, N.F. & Simonsen, P.
Universitetsforlag 2021. [Accepted, in press].

"… Above All, It's a Matter of This Person's Quality of Life": Health Care Professionals' Perspectives on Deprescribing in Older Patients With Limited Life Expectancy.
Lundby C, Graabæk T, Ryg J, Søndergaard J, Pottegård A, Nielsen DS.
Gerontologist. 2020 Apr 2;60(3):439-449

Preparing for the future: The changing demographic composition of hospital patients in Denmark between 2013 and 2050.
Oksuzyan A, Höhn A, Krabbe Pedersen J, Rau R, Lindahl-Jacobsen R, Christensen K.
PLoS One 2020;15(9):e0238912.

Motion-Based Technology for People With Dementia Training at Home: Three-Phase Pilot Study Assessing Feasibility and Efficacy.
Petersen JD, Larsen EL, la Cour K, von Bülow C, Skouboe M, Christensen JR, Waldorff FB.
JMIR Ment Health. 2020 Aug 26;7(8):e19495.

Clinical management of hip fractures in elderly patients with dementia and postoperative 30-day mortality: A population-based cohort study.
Petersen JD, Siersma VD, Wehberg S, Nielsen CT, Viberg B, Waldorff FB.
Brain Behav. 2020 Nov;10(11):e01823.

Use of prescription medication in the last years of life: a population-based comparison of two oldest old Danish birth cohorts born 10 years apart.
Pedersen JK, Jensen TM, Waldorff FB, Søndergaard J, Christensen K.
Age and Ageing 2020;49(6):1105-1109.

Polyfarmaci - et dilemma.
Søndergaard J, Andersen JS.
Ugeskr Læger 2020;182:V205028

Er alder og køn de eneste vigtigste indikatorer for et individs forventede restlevetid?
Thinggaard M, Christensen K.
Gerontologi (Aldring og Ældre/Forskning og Udvikling) 2020, Nr. 1, årgang 36, side 28-29.

Are advances in survival among the oldest old seen across the spectrum of health and functioning?
Thinggaard M, Jeune B, Osler M, Vaupel JW, McGue M, Christensen K.
Journals of the Gerontology, Series A, Biological Sciences and Medical Sciences 2020;75(12):2354-2360.

2019

Workload and empathy in general practice

Charles JA, Ahnfeldt-Mollerup P, Søndergaard J, Kristensen T.
I: Linde P (red.): Symposium i Anvendt Statistik 2019, s. 65-79; Københavns Universitet, 2019.

 

Gene-lifestyle interactions in longevity

Lindahl-Jacobsen R & Christensen K.
I: Fernández-Ballesteros R, Benetos A & Robine J-M (red.): Cambridge Handbook of Successful Aging, s. 91-109; Cambridge University Press, New York, 2019.

 

Hvordan griber vi det kommende nære sundhedsvæsen an?
Pedersen KM, Pedersen LV, Søndergaard J. 
Ugeskrift for Laeger. 2019 Dec.

Israel kan lære os om den nære sundhed: Det danske sundhedsvæsen er ikke perfekt. 
Vi har udfordringer med mangel på speciallæger og med tværsektorielle patientforløb, og vi har et sundhedsvæsen, som udfordres af en eksplosion af ældre patienter. Men kan vi lære af andre landes systemer?
Schloss J, Søndergaard J, Jylling E.
Jyllands-Posten. 2019 Dec.


Older multimorbid patients' experiences on integration of services: a systematic review

Boye LK, Mogensen CB, Mechlenborg T, Waldorff FB, Andersen PT.

BMC Health Serv Res. 2019 Nov;19(1):795. PubMed

 

Brief Assessment of Impaired Cognition (BASIC)-Validation of a new dementia case-finding instrument integrating cognitive assessment with patient and informant report.

Jørgensen K, Nielsen TR, Nielsen A, Waldorff FB, Høgh P, Jakobsen S, Gottrup H, Vestergaard K, Waldemar G.

Int J Geriatr Psychiatry. 2019 Nov;34(11):1724-1733. PubMed

 

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies.
Mengel-From J, Svane AM, Pertoldi C, Kristensen TN, Loeschcke V, Skytthe A, Christensen K, Lindahl-Jacobsen R, Hjelmborg J, Christiansen L.
J Gerontol A Biol Sci Med Sci. 2019 Nov;74(12):1853-1860. Pubmed abstract

 

Tendens: Jo, man kan skrive gode digte om seniorsex og besvær med vandladning.
NF Lund & Simonsen P.
Jyllands-Posten; 14. sept. 2019.

 

"I'll sing about those who are gay, and those who are sorrowful": The use of Hans Christian Andersen's Fairy Tales in Narrative Medicine
Rasmussen AJ & Mai AM.
I: Bom AK, Bøggild J & Frandsen JN (red.): Hans Christian Andersen and Community, s. 341-358; Syddansk Universitetsforlag, 2019.

 

Poetry and Age
Simonsen P.
I: Gu D & Dupre ME (red.): Encyclopedia of Gerontology and Population Aging; Springer, 2019.


Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Soerensen M, Li W, Debrabant B, Nygaard M, Mengel-From J, Frost M, Christensen K, Christiansen L, Tan Q.

Biogerontology. 2019 Oct;20(5):627-647. Pubmed abstract

 

Declining cancer incidence at the oldest ages: Hallmark of aging or lower diagnostic activity?

Pedersen JK, Rosholm JU, Ewertz M, Engholm G, Lindahl-Jacobsen R, Christensen K.

J Geriatr Oncol. 2019 Sep;10(5):792-798. Pubmed abstract

 

Epigenome-wide association study of depression symptomatology in elderly monozygotic twins.

Starnawska A, Tan Q, Soerensen M, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.

Transl Psychiatry. 2019 Sep;9(1):214. Pubmed abstract

 

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Deelen J, Nygaard M, Christensen K, Christiansen L, Debrabant B, Vaupel JW, Murabito JM et al.

Nat Commun. 2019 Aug;10(1):3669. Pubmed abstract

 

Hvad hvis sygehusene og det nære sundhedsvæsen bytter plads?
Inspirationen til organiseringen af fremtidens danske sundhedssektor kan komme fra Israel, hvor man er gået all in på det nære sundhedsvæsen.
Schloss J, Søndergaard J.
Tidsskrift for Dansk Sundhedsvæsen. 2019 Jun; 95(4):24-29. DSS Online

Optimizing the Feasibility and Scalability of a Geriatric Surgery Quality Improvement Initiative.
Hornor MA, Tang VL, Berian J, Robinson TN, Coleman J, Katlic MR, Rosenthal RA, Christensen K, Baker T, Finlayson E, Lagoo-Deenadaayalan SA, Ko CY, Russell MM.
J Am Geriatr Soc. 2019 May; 67(5):1074-1078. Pubmed abstract

Health care professionals' attitudes towards deprescribing in older patients with limited life expectancy: a systematic review.

Lundby C, Graabaek T, Ryg J, Søndergaard J, Pottegård A, Nielsen D.

Br J Clin Pharmacol. 2019 May;85(5):868-892. Pubmed abstract

 

A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Marron MM, Miljkovic I, Boudreau RM, Christensen K, Feitosa MF, Lee JH, Sebastiani P, Thyagarajan B, Wojczynski MK, Zmuda JM, Newman AB; Long Life Family Study.

Metabolism. 2019 May;94:28-38. Pubmed abstract
  

The Effect of Economic Assets on Mortality in Patients with Dementia: A Population-Based Cohort Study.
Bebe A, Siersma V, Kragstrup J, Nielsen ABS, Møller A, Søndergaard J, Rós Nicolaisdóttir D, Waldorff FB.
J Alzheimers Dis. 2019 Apr;67(4):1245-1253. Pubmed abstract

 

A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Medford A, Christensen K, Skytthe A, Vaupel JW.

Demography. 2019 Apr;56(2):665-677. Pubmed abstract

 

Hvad hvis sygehusene og det nære sundhedsvæsen bytter plads?
Inspirationen til organiseringen af fremtidens danske sundhedssektor kan komme fra Israel, hvor man er gået all in på det nære sundhedsvæsen. 
Jonatan Schloss og Jens Søndergaard.
Tidsskrift for Dansk Sundhedsvæsen. Apr. 2019. Læs online: DSS
 

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.
Skytthe A, Harris JR, Czene K, Mucci L, Adami HO, Christensen K, Hjelmborg J, Holm NV, Nilsen TS, Kaprio J, Pukkala E.
Twin Res Hum Genet. 2019 Apr;22(2):99-107Pubmed abstract

 

Trends in Hospital Deaths in Denmark from 1980 to 2014, at Ages 50 and Older.

Carollo A, Verdiell NC, Hale JM, Andersen-Ranberg K, Lindahl-Jacobsen R, Oksuzyan A.

J Am Geriatr Soc. 2019 Mar;67(3):471-476. Pubmed abstract

 

Dementia and road traffic accidents among non-institutionalized older people in Denmark: A Danish register-based nested case-control study

Petersen JD, Siersma VD, Depont Christensen R, Storsveen MM, Nielsen CT, Vass M, Waldorff FB.

Scand J Public Health. 2019 Mar;47(2):221-228. PubMed

 

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts.

Jylhävä J, Hjelmborg J, Soerensen M, Munoz E, Tan Q, Kuja-Halkola R, Mengel-From J, Christensen K, Christiansen L, Hägg S, Pedersen NL, Reynolds CA.

EBioMedicine. 2019 Feb;40:710-716. Pubmed abstract

 

Hearing loss, cognitive ability, and dementia in men age 19-78 years.

Osler M, Christensen GT, Mortensen EL, Christensen K, Garde E, Rozing MP.

Eur J Epidemiol. 2019 Feb;34(2):125-130. Pubmed abstract

 

Polyfarmaci og almen praksis.

Andersen JS, Bro F, Søndergaard J, Thomsen JL.

Ugeskr Laeger. 2019 Jan 21;181(4). Ugeskriftet

 

Intergenerational relations and social mobility: Social inequality in physical function in old age.

Jørgensen TSH, Nilsson CJ, Lund R, Siersma V, Fors S.

Arch Gerontol Geriatr. 2019 Jan;80:58-64. Pubmed abstract

 

Mobility limitation as determinant of primary care use and ambulatory care sensitive conditions.
Jørgensen TSH, Siersma V, Lund R, Nilsson CJ.
Eur Geriatr Med. 2019 Feb;10(1):53-60.

 

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Kraja AT, Christensen K et al.

Am J Hum Genet. 2019 Jan;104(1):112-138. Pubmed abstract

 

Independent associations of TOMM40 and APOE variants with body mass index.
Kulminski AM, Loika Y, Culminskaya I, Huang J, Arbeev KG, Bagley O, Feitosa MF, Zmuda JM, Christensen K, Yashin AI; Long Life Family Study Research Group.
Aging Cell. 2019 Feb;18(1):e12869. Pubmed abstract

 

Digital Recruitment and Acceptance of a Stepwise Model to Prevent Chronic Disease in the Danish Primary Care Sector: Cross-Sectional Study.

Larsen LB, Sondergaard J, Thomsen JL, Halling A, Sønderlund AL, Christensen JR, Thilsing T.

J Med Internet Res. 2019 Jan 21;21(1):e11658. Pubmed abstract

 

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns.

Lund JB, Li S, Baumbach J, Svane AM, Hjelmborg J, Christiansen L, Christensen K, Redmond P, Marioni RE, Deary IJ, Tan Q.

Clin Epigenetics. 2019 Feb;11(1):23. Pubmed abstract

 

Diagnosing heart failure in centenarians.

Rasmussen SH, Andersen-Ranberg K, Dahl JS, Nybo M, Jeune B, Christensen K, Gill S.

J Geriatr Cardiol. 2019 Jan;16(1):1-11. Pubmed abstract

 

APOE Alleles and Extreme Human Longevity.

Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, Perls TT.

J Gerontol A Biol Sci Med Sci. 2019 Jan;74(1):44-51. Pubmed abstract

 

Tools for Deprescribing in Frail Older Persons and Those with Limited Life Expectancy: A Systematic Review.

Thompson W, Lundby C, Graabaek T, Nielsen DS, Ryg J, Søndergaard J, Pottegård A.

J Am Geriatr Soc. 2019 Jan;67(1):172-180. Pubmed abstract


Selected publications: