Forskningspublikationer

Age-dependent DNA methylation patterns on the Y chromosome in elderly males.
Lund JB, Li S, Christensen K, Mengel-From J, Soerensen M, Marioni RE, Starr J, Pattie A, Deary IJ, Baumbach J, Tan Q.
Aging Cell. 2019. Pubmed abstract [Epub ahead of print]

"… Above All, It's a Matter of This Person's Quality of Life"
Health Care Professionals' Perspectives on Deprescribing in Older Patients With Limited Life Expectancy.
Lundby C, Graabæk T, Ryg J, Søndergaard J, Pottegaard A, Nielsen DS.
Gerontologist. 2019. Pubmed abstract [Epub ahead of print]

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies.
Mengel-From J, Svane AM, Pertoldi C, Kristensen TN, Loeschcke V, Skytthe A, Christensen K, Lindahl-Jacobsen R, Hjelmborg J, Christiansen L.
J Gerontol A Biol Sci Med Sci. 2019. Pubmed abstract [Epub ahead of print] 

Parallel progress in perceived age and life expectancy.

Steiner UK, Larsen LA, Christensen K.
J Gerontol A Biol Sci Med Sci. 2019. Pubmed abstract [Epub ahead of print]


Workload and empathy in general practice

Charles JA, Ahnfeldt-Mollerup P, Søndergaard J, Kristensen T.
I: Linde P (red.): Symposium i Anvendt Statistik 2019, s. 65-79; Københavns Universitet, 2019.

 

Gene-lifestyle interactions in longevity

Lindahl-Jacobsen R & Christensen K.
I: Fernández-Ballesteros R, Benetos A & Robine J-M (red.): Cambridge Handbook of Successful Aging, s. 91-109; Cambridge University Press, New York, 2019.

 

"I'll sing about those who are gay, and those who are sorrowful": The use of Hans Christian Andersen's Fairy Tales in Narrative Medicine
Rasmussen AJ & Mai AM.
I: Bom AK, Bøggild J & Frandsen JN (red.): Hans Christian Andersen and Community, s. 341-358; Syddansk Universitetsforlag, 2019.

 

Poetry and Age
Simonsen P.
I: Gu D & Dupre ME (red.): Encyclopedia of Gerontology and Population Aging; Springer, 2019.


Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.

Soerensen M, Li W, Debrabant B, Nygaard M, Mengel-From J, Frost M, Christensen K, Christiansen L, Tan Q.

Biogerontology. 2019 Oct;20(5):627-647. Pubmed abstract

 

Declining cancer incidence at the oldest ages: Hallmark of aging or lower diagnostic activity?

Pedersen JK, Rosholm JU, Ewertz M, Engholm G, Lindahl-Jacobsen R, Christensen K.

J Geriatr Oncol. 2019 Sep;10(5):792-798. Pubmed abstract

 

Epigenome-wide association study of depression symptomatology in elderly monozygotic twins.

Starnawska A, Tan Q, Soerensen M, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.

Transl Psychiatry. 2019 Sep;9(1):214. Pubmed abstract

 

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Deelen J, Nygaard M, Christensen K, Christiansen L, Debrabant B, Vaupel JW, Murabito JM et al.

Nat Commun. 2019 Aug;10(1):3669. Pubmed abstract

 

Optimizing the Feasibility and Scalability of a Geriatric Surgery Quality Improvement Initiative.
Hornor MA, Tang VL, Berian J, Robinson TN, Coleman J, Katlic MR, Rosenthal RA, Christensen K, Baker T, Finlayson E, Lagoo-Deenadaayalan SA, Ko CY, Russell MM.
J Am Geriatr Soc. 2019 May; 67(5):1074-1078. Pubmed abstract

Health care professionals' attitudes towards deprescribing in older patients with limited life expectancy: a systematic review.

Lundby C, Graabaek T, Ryg J, Søndergaard J, Pottegård A, Nielsen D.

Br J Clin Pharmacol. 2019 May;85(5):868-892. Pubmed abstract

 

A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Marron MM, Miljkovic I, Boudreau RM, Christensen K, Feitosa MF, Lee JH, Sebastiani P, Thyagarajan B, Wojczynski MK, Zmuda JM, Newman AB; Long Life Family Study.

Metabolism. 2019 May;94:28-38. Pubmed abstract
  

The Effect of Economic Assets on Mortality in Patients with Dementia: A Population-Based Cohort Study.
Bebe A, Siersma V, Kragstrup J, Nielsen ABS, Møller A, Søndergaard J, Rós Nicolaisdóttir D, Waldorff FB.
J Alzheimers Dis. 2019 Apr;67(4):1245-1253. Pubmed abstract

 

A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Medford A, Christensen K, Skytthe A, Vaupel JW.

Demography. 2019 Apr;56(2):665-677. Pubmed abstract

 

Hvad hvis sygehusene og det nære sundhedsvæsen bytter plads?
Inspirationen til organiseringen af fremtidens danske sundhedssektor kan komme fra Israel, hvor man er gået all in på det nære sundhedsvæsen. 
Jonatan Schloss og Jens Søndergaard.
Tidsskrift for Dansk Sundhedsvæsen. Apr. 2019. Læs online: DSS
 

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers.
Skytthe A, Harris JR, Czene K, Mucci L, Adami HO, Christensen K, Hjelmborg J, Holm NV, Nilsen TS, Kaprio J, Pukkala E.
Twin Res Hum Genet. 2019 Apr;22(2):99-107Pubmed abstract

 

Trends in Hospital Deaths in Denmark from 1980 to 2014, at Ages 50 and Older.

Carollo A, Verdiell NC, Hale JM, Andersen-Ranberg K, Lindahl-Jacobsen R, Oksuzyan A.

J Am Geriatr Soc. 2019 Mar;67(3):471-476. Pubmed abstract

 

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts.

Jylhävä J, Hjelmborg J, Soerensen M, Munoz E, Tan Q, Kuja-Halkola R, Mengel-From J, Christensen K, Christiansen L, Hägg S, Pedersen NL, Reynolds CA.

EBioMedicine. 2019 Feb;40:710-716. Pubmed abstract

 

Hearing loss, cognitive ability, and dementia in men age 19-78 years.

Osler M, Christensen GT, Mortensen EL, Christensen K, Garde E, Rozing MP.

Eur J Epidemiol. 2019 Feb;34(2):125-130. Pubmed abstract

 

Polyfarmaci og almen praksis.

Andersen JS, Bro F, Søndergaard J, Thomsen JL.

Ugeskr Laeger. 2019 Jan 21;181(4). Ugeskriftet

 

Intergenerational relations and social mobility: Social inequality in physical function in old age.

Jørgensen TSH, Nilsson CJ, Lund R, Siersma V, Fors S.

Arch Gerontol Geriatr. 2019 Jan;80:58-64. Pubmed abstract

 

Mobility limitation as determinant of primary care use and ambulatory care sensitive conditions.
Jørgensen TSH, Siersma V, Lund R, Nilsson CJ.
Eur Geriatr Med. 2019 Feb;10(1):53-60.

 

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Kraja AT, Christensen K et al.

Am J Hum Genet. 2019 Jan;104(1):112-138. Pubmed abstract

 

Independent associations of TOMM40 and APOE variants with body mass index.
Kulminski AM, Loika Y, Culminskaya I, Huang J, Arbeev KG, Bagley O, Feitosa MF, Zmuda JM, Christensen K, Yashin AI; Long Life Family Study Research Group.
Aging Cell. 2019 Feb;18(1):e12869. Pubmed abstract

 

Digital Recruitment and Acceptance of a Stepwise Model to Prevent Chronic Disease in the Danish Primary Care Sector: Cross-Sectional Study.

Larsen LB, Sondergaard J, Thomsen JL, Halling A, Sønderlund AL, Christensen JR, Thilsing T.

J Med Internet Res. 2019 Jan 21;21(1):e11658. Pubmed abstract

 

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns.

Lund JB, Li S, Baumbach J, Svane AM, Hjelmborg J, Christiansen L, Christensen K, Redmond P, Marioni RE, Deary IJ, Tan Q.

Clin Epigenetics. 2019 Feb;11(1):23. Pubmed abstract

 

Diagnosing heart failure in centenarians.

Rasmussen SH, Andersen-Ranberg K, Dahl JS, Nybo M, Jeune B, Christensen K, Gill S.

J Geriatr Cardiol. 2019 Jan;16(1):1-11. Pubmed abstract

 

APOE Alleles and Extreme Human Longevity.

Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, Perls TT.

J Gerontol A Biol Sci Med Sci. 2019 Jan;74(1):44-51. Pubmed abstract

 

Tools for Deprescribing in Frail Older Persons and Those with Limited Life Expectancy: A Systematic Review.

Thompson W, Lundby C, Graabaek T, Nielsen DS, Ryg J, Søndergaard J, Pottegård A.

J Am Geriatr Soc. 2019 Jan;67(1):172-180. Pubmed abstract



Selected publications:

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