CV
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Curriculum Vitae
Erik Bjerregaard Pedersen
Personal data: Born 13 July, 1945 in Timring, Denmark
Nationality: Danish
Marital Status:
Married to Inger Line Pedersen, born 25 April, 1946
Children Morten Bjerregaard Pedersen, born 20 December, 1969 and Klaus Bjerregaard Pedersen, born 14 June, 1972
University address:
Nucleic Acid Center, Department of Physics and Chemistry,
University of Southern Denmark, Odense, Campusvej 55, DK-5230 Odense M, Denmark
Tel. +45 65 50 25 55 Fax +45 66 15 87 80
Email ebp@chem.sdu.dk
www.sdu.dk/Nat/Chem/STAFF/sci/EbpE.html
Private address:
Lisas Alle 22,
DK-5230 Odense SV, Denmark
Tel. +45 66172099
General Certificate: 1964, Th. Langs Gymnasium, Silkeborg, Denmark
University education:
Cand.scient. (M.Sc.) 1970, University of Aarhus, Denmark. Lic.scient. (Ph.D.) 1974, University of Aarhus, with Lektor
S.-O. Lawesson as supervisor
Positions held:
1970-1972, Kandidatstipendiat (Research Assistant) and
1972-1974, Seniorstipendiat (Senior Research Assistant) at Department of Chemistry, University of Aarhus, Denmark
1974, Postdoc at Professor U. Schöllkopf at Universität Göttingen, Germany
1974 - , Lektor (Associate Professor) at Department of Physics and Chemistry, University of Southern Denmark – Odense
Awards:
2008 “Industrial Prize” from The Danish Academy of Natural Sciences
Present research: Modified oligonucleotides and Anti-HIV drugs
Publications: More than.300 publications in peer-reviewed journals
Patents:
Eur. Pat. Appl. (1985), 49 pp. EP 155911
PCT Int. Appl. (2003), 313 pp. WO 2003051901
PCT Int. Appl. (2003), 264 pp. WO 2003052132
PCT Int. Appl. (2003), 274 pp. WO 2003052133
PCT Int. Appl. (2003), 264 pp. WO 2003052134
PCT Int. Appl. (2003), 65 pp. WO 2003057677
PCT Int. Appl. (2005), 31 pp. WO 2005083084
PCT Int. Appl. (2006), 54pp. WO 2006125447
PCT Int. Appl. (2008), 52pp. WO 2008067825
Reviews:
Pedersen, O. S.; Pedersen, E. B. Non-nucleoside reverse transcriptase inhibitors. The NNRTI boom. Antiviral Chem. Chemother. 10, 285-314 (1999).
Pedersen, O. S.; Pedersen, E. B. The flourishing syntheses of non-nucleoside reverse transcriptase inhibitors (NNRTIs). Synthesis 2000, 479-495.
Major projects:
Enreca 1992-2005. Research capacity building on hepatitis drug discovery in Egypt. (18.8 mio. DKK)
Danish Chemistry Programme 1997-2001. Estalishment of medicinal Chemistry in Odense. (3.5 mio. DKK)
Participating in Nucleic Acid Center under Danish National Research Foundation. 2001-
EU project on microbicides (SHIVA) 2004-2009 (593,730 EUR)
EU Madame Curie training centre on Nucleic Acid Based Drug Design (NAC-DRUG) 2004-2008 (1.65 mio. EUR)
PhD School NAC-DRUG 2005-2011 ( 3 grants, 3.62 mio DKK)
Administration:
1981-1986 and 1993-1995, member of the board at Department of Chemistry
1983-1985, vice-chairman and 1985-1986 chairman of Department of Chemistry
1985-1989 Member of the board of Section of Organic Chemistry and
1996-1998 member of the board of The Danish Chemical Society;
1989-1992, member of the Faculty Council of Science
2003-2004 Member of Fagligt Forum, STVF
2005-2007 Member of Academic Council, Faculty of Science, SDU
2006- Research Leader for the section of Synthesis and Medicinal Chemistry including NMR, MS and pharmacy at Department of Physics and Chemistry.
Teaching:
Biomolecular Chemistry (Lectures in chemistry)
Organic Chemical Separation (Laboratory course)
Physical Organic Chemistry (Lec
Publications
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VALIDATED
Conjugation of a 3-(1H-phenanthro[9,10-d]imidazol-2-yl)-1H-indole intercalator to a triplex oligonucleotide and to a three-way junction.
/ Fatthalla, Maha I ; Elkholy, Yehya M ; Abbas, Nermeen S ; Mandour, Adel H
; Jørgensen, Per T; Bomholt, Niels; Pedersen, Erik Bjerregaard
.
I
: Bioorganic & Medicinal Chemistry Letters
, Vol. 20, Nr. 1, 2012, s. 207-14.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
Synthesis and Anti-HIV-1 Activity of New Fluoro-HEPT Analogues: An Investigation on Fluoro versus Hydroxy Substituents.
/
Loksha, Yasser M; Pedersen, Erik Bjerregaard
; Loddo, Roberta ; La Colla, Paolo.
I
: Archiv der Pharmazie
, Vol. 344, Nr. 6, 2011, s. 366-71.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
Increasing the Analytical Sensitivity by Oligonucleotides Modified with Para- and Ortho-Twisted Intercalating Nucleic Acids - TINA.
/ Schneider, Uffe V
; Géci, Imrich
; Jøhnk, Nina ; Mikkelsen, Nikolaj Dam
; Pedersen, Erik Bjerregaard
; Lisby, Gorm.
I
: P L o S One
, Vol. 6, Nr. 6, 2011, s. e20565.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
Cationic modified nucleic acids for use in DNA hairpins and parallel triplexes.
/
Bomholt, Niels
; Filichev, Vyacheslav V
; Pedersen, Erik Bjerregaard
.
I
: Organic & Biomolecular Chemistry
, Vol. 9, 2011, s. 4527-4534.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
Synthesis of locked pyranosyl nucleic acid (LpNA).
/
Bomholt, Niels; Jørgensen, Per Trolle; Pedersen, Erik B
.
I
: Bioorganic & Medicinal Chemistry Letters
, Vol. 21, Nr. 24, 2011, s. 7376-7378.
Publikation
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Forskning - peer review
›Artikel
VALIDATED
PYRENE INTERCALATING NUCLEIC ACIDS WITH A CARBON LINKER.
/ Østergaard, Michael E.
; Wamberg, Michael Chr.; Pedersen, Erik Bjerregaard
.
I
: Nucleosides, Nucleotides and Nucleic Acids
, Vol. 30, 2011, s. 210-226.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids.
/
Pedersen, Erik Bjerregaard; Nielsen, Jakob Toudahl
; Nielsen, Claus ; Filichev, Vyacheslav V.
I
: Nucleic Acids Research
, Vol. 39, Nr. 6, 2011, s. 2470-2481.
Publikation
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Forskning - peer review
›Artikel
VALIDATED
Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA.
/ Zaghloul, Eman M
; Madsen, Andreas S
; Moreno, Pedro M D ; Oprea, Iulian I ; El-Andaloussi, Samir ; Bestas, Burcu
; Gupta, Pankaj; Pedersen, Erik B
; Lundin, Karin E
; Wengel, Jesper
; Smith, C I Edvard.
I
: Nucleic Acids Research
, Vol. 39, Nr. 3, 01.02.2011, s. 1142-54.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy.
/ Membrino, Alexandro ; Cogoi, Susanna
; Pedersen, Erik Bjerregaard
; Xodo, Luigi E..
I
: P L o S One
, Vol. 6, Nr. 9, 2011, s. e24421.
Publikation
:
Forskning - peer review
›Artikel
VALIDATED
Biomolecular Chemistry - third edition.
/
Kirpekar, Finn (Redaktør); Pedersen, Erik Bjerregaard (Redaktør)
.
3. udg. Harlow, England : Pearson Education Limited, 2011.
Publikation
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