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Publikationsliste: IDEAL

Determinants of Healthy Aging. Studies of genetic variation Associated with human longevity.
Nygaard M.
P.hd. afhandling. 2015 Jun. Free download

Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals.
Soerensen M, Nygaard M, Dato S, Stevnsner T, Bohr VA, Christensen K, Christiansen L.
Aging Cell. 2015 Feb;14(1):60-6. Pubmed abstract

Twin methodology in epigenetic studies
Tan Q, Christiansen L, Hjelmborg JB, Christensen K.
J.Exp.Biol. 2015 Jan;218(1):134-9. Twin methodology in epigenetic studies

2014

Contribution of genetic polymorphisms on functional status at very old age: A gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
Dato S, Soerensen M, Lagani V, Montesanto A, Passarino G, Christensen K, Tan Q, Christiansen L.
Exp.Gerontol. 2014 Apr;52:23-9.

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.
Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guethbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, Nygaard M, Cordell HJ, Crocco P, van den Akker EB, Böhringer S, Helmer Q, Nelson CP, Saunders GI, Alver M, Andersen-Ranberg K, Breen ME, van der Breggen R, Caliebe A, Capri M, Cevenini E, Collerton JC, Dato S, Davies K, Ford I, Gampe J, Garagnani P, de Geus EJ, Harrow J, van Heemst D, Heijmans BT, Heinsen FA, Hottenga JJ, Hofman A, Jeune B, Jonsson PV, Lathrop M, Lechner D, Martin-Ruiz C, Mcnerlan SE, Mihailov E, Montesanto A, Mooijaart SP, Murphy A, Nohr EA, Paternoster L, Postmus I, Rivadeneira F, Ross OA, Salvioli S, Sattar N, Schreiber S, Stefansson H, Stott DJ, Tiemeier H, Uitterlinden AG, Westendorp RG, Willemsen G, Samani NJ, Galan P, Sorensen TI, Boomsma DI, Jukema JW, Rea IM, Passarino G, de Craen AJ, Christensen K, Nebel A, Stefansson K, Metspalu A, Magnusson P, Blanche H, Christiansen L, Kirkwood TB, van Duijn CM, Franceschi C, Houwing-Duistermaat JJ, Slagboom PE.
Hum.Mol.Genet. 2014 Aug;23(16):4420-32.

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly.
Mengel-From J, Thinggaard M, Dalgård C, Kyvik KO, Christensen K, Christiansen L.
Hum.Genet. 2014 Sep;133(9):1149-59.

Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals.
Nygaard M, Lindahl-Jacobsen R, Soerensen M, Mengel-From J, Andersen-Ranberg K, Jeune B, Vaupel JW, Tan Q, Christiansen L, Christensen K.
Exp.Gerontol. 2014 Sep;57(9):41-6.

Epigenetic signature of birth weight discordance in adult twins.
Tan Q, Frost M, Heijmans BT, Hjelmborg JB, Tobi EW, Christensen K, Christiansen L.
BMC. Genomics 2014;15:1062-

2013

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study.
Beekman M, Blanché H, Perola M, Hervonen A, Bezrukov V, Sikora E, Flachsbart F, Christiansen L, De Craen AJ, Kirkwood TB, Rea IM, Poulain M, Robine JM, Valensin S, Stazi MA, Passarino G, Deiana L, Gonos ES, Paternoster L, Sørensen TI, Tan Q, Helmer Q, van den Akker EB, Deelen J, Martella F, Cordell HJ, Ayers KL, Vaupel JW, Törnwall O, Johnson TE, Schreiber S, Lathrop M, Skytthe A, Westendorp RG, Christensen K, Gampe J, Nebel A, Houwing-Duistermaat JJ, Slagboom PE, Franceschi C; the GEHA consortium.
Aging Cell. 2013 Apr;12(2):184-93. doi: 10.1111/acel.12039. Pubmed abstract

Regulation of the pituitary-thyroid axis in adulthood is not related to birth weight. Evidence from extremely birth weight discordant monozygotic Danish twin pairs.
Frost M, Petersen I, Hegedus L, Christiansen L, Heiberg Brix T, Christensen K.
Thyroid. 2013 Jul;23(7):785-90. Pubmed abstract

Birth weight and adult bone metabolism are unrelated: results from birth weight-discordant monozygotic twins.
Frost M, Petersen I, Andersen TL, Langdahl BL, Buhl T, Christiansen L, Brixen K, Christensen K.
J Bone Miner Res 2013 Dec;28(12):2561-9.

Twins for epigenetic studies of human aging and Development.
Tan Q, Christiansen L, Thomassen M, Kruse TA, Christensen K.
Ageing Res.Rev. 2013 Jan;12(1):182-7.

A novel permutation test for case-only analysis identifies epistatic effects on human longevity in the FOXO gene Family.
Tan Q, Soerensen M, Kruse TA, Christensen K, Christiansen L.
Aging Cell 2013 Aug;12(4):690-4.

2012

UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts.
Dato S, Soerensen M, Montesanto A, Lagani V, Passarino G, Christensen K, Christiansen L.
Mech Ageing Dev. 2012 Aug;133(8):530-7. Pubmed abstract

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: Cross sectional and longitudinal studies.
Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Jacobsen R, Suchiman HE, de Craen AJ, Westendorp RG, Schreiber S, Stevnsner T, Bohr VA, Slagboom PE, Nebel A, Vaupel JW, Christensen K, McGue M, Christiansen L.
Exp Gerontol 2012 May; 47(5):379-87. Pubmed abstract

Epigenetic variation during the adult lifespan: Cross-sectional and longitudinal data on monozygotic twin pairs.
Talens RP, Christensen K, Putter H, Willemsen G, Christiansen L, Kremer D, Suchiman HE, Slagboom PE, Boomsma DI, Heijmans BT.
Aging Cell. 2012 Aug;11(4):694-703. Pubmed abstract - Open Access

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