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Seneste publikationer

The association between depression and mortality - a comparison of survey- and register-based measures of depression.
Christensen GT, Maartensson S, Osler M.
J Affect Disord. 2017 Mar;210:111-4.  Pubmed abstract

Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years.
Sandahl K, Nielsen LB, Svensson J, Johannesen J, Pociot F, Mortensen HB, Hougaard P, Broe R, Rasmussen ML, Grauslund J, Peto T, Olsen BS.
Diabet Med. 2017 Mar;34(3):380-6. Pubmed abstract

Early-life mortality risks in opposite-sex and same-sex twins: a Danish cohort study of the twin testosterone transfer hypothesis.
Ahrenfeldt LJ, Larsen LA, Lindahl-Jacobsen R, Skytthe A, Hjelmborg JV, Möller S, Christensen K.
Ann Epidemiol. 2017 Feb;27(2):115-120.e2. Pubmed abstract

Efficient detection of differentially methylated regions using DiMmeR.
Almeida D, Skov I, Silva A, Vandin F, Tan Q, Röttger R, Baumbach J.
Bioinformatics. 2017 Feb 15;33(4):549-551. Pubmed abstract

Mortality changes in industrialized societies: past, present and future.
Marie-Pier Bergeron Boucher.
Ph.d. afhandling. 2017 Feb; University of Southern Denmark, MaxO.

Mexico's epidemic of violence and its public health significance on average length of life.
Canudas-Romo V, Aburto JM, García-Guerrero VM, Beltrán-Sánchez H.
J Epidemiol Community Health. 2017 Feb;71(2):188-193. Pubmed abstract

The Efficacy of Assisted Reproduction in Women with Inflammatory Bowel Disease and the Impact of Surgery-A Nationwide Cohort Study.
Friedman S, Larsen PV, Fedder J, Nørgård BM.
Inflamm Bowel Dis. 2017 Feb;23(2):208-217. Pubmed abstract

Efficient Management of High-Throughput Screening Libraries with SAVANAH.
List M, Elnegaard MP, Schmidt S, Christiansen H, Tan Q, Mollenhauer J, Baumbach J.
J Biomol Screen. 2017 Feb;22(2):196-202. Pubmed abstract

Disparities in multimorbidity across Europe - Findings from the SHARE Survey
Nielsen CR, Halling A, Andersen-Ranberg K.
Eur Ger. 2017 Feb;8(1):16-21.

Midlife Cognitive Ability, Education, and Tooth Loss in Older Danes.
Bachkati KH, Mortensen EL, Brønnum-Hansen H, Holm-Pedersen P.
J Am Geriatr Soc. 2017 Jan;65(1):194-9. Pubmed abstract

Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.
Bousquet J,  Andersen-Ranberg K et al.
J Nutr Health Aging. 2017;21(1):92-104. Pubmed abstract

Exploring Subclinical Phenotypic Features in Twin Pairs Discordant for Cleft Lip and Palate.
Leslie EJ, Carlson JC, Cooper ME, Christensen K, Weinberg SM, Marazita ML.
Cleft Palate Craniofac J. 2017 Jan;54(1):90-93. Pubmed abstract

Investigation of the 5q33.3 longevity locus and age-related phenotypes.
Nygaard M, Thinggaard M, Christensen K, Christiansen L.
Aging (Albany NY). 2017 Jan 13;9(1):247-255. Pubmed abstract

Investigating heredity in cutaneous T-cell lymphoma in a unique cohort of Danish twins.
Odum N, Lindahl L, Wod M, Krejsgaard T, Skytthe A, Woetmann A, Iversen L, Christensen K.
Blood Cancer Journal 2017 Jan;7(1):e517.

The Survival of Spouses Marrying Into Longevity-Enriched Families.
Pedersen JK, Elo IT, Schupf N, Perls TT, Stallard E, Yashin AI, Christensen K.
J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):109-114. Pubmed abstract

Disease-Concordant Twins Empower Genetic Association Studies.
Tan Q, Li W, Vandin F.
Ann Hum Genet. 2017 Jan;81(1):20-26. Pubmed abstract

2016

Genetic Influence on the Peripheral Blood CD4+ T-cell Differentiation Status in CMV Infection.
Goldeck D, Larsen LA, Christiansen L, Christensen K, Hamprecht K, Pawelec G, Derhovanessian E.
J Gerontol A Biol Sci Med Sci. 2016 Dec;71(12):1537-1543. Pubmed abstract

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.
Jelenkovic A, Tan Q, Christensen K, Skytthe A, Kyvik KO, McGue M, Hjelmborg JB et al.
Elife. 2016 Dec;5. pii: e20320. Pubmed abstract

Why did Danish women's life expectancy stagnate? The influence of interwar generations' smoking behaviour.
Lindahl-Jacobsen R, Oeppen J, Rizzi S, Möller S, Zarulli V, Christensen K, Vaupel JW.
Eur J Epidemiol. 2016 Dec;31(12):1207-11. Pubmed abstract

Heritability of caffeine metabolism: Environmental effects masking genetic effects on CYP1A2 activity but not on NAT2.
Matthaei J, Tzvetkov MV, Strube J, Sehrt D, Sachse-Seeboth C, Hjelmborg JB, Möller S, Halekoh U, Hofmann U, Schwab M, Kerb R, Brockmöller J.
Clin Pharmacol Ther. 2016 Dec;100(6):606-616. Pubmed abstract

Physical Characteristics of a Citrullinated Pro-Filaggrin Epitope Recognized by Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Sera.
Trier NH, Holm BE, Slot O, Locht H, Lindegaard H, Svendsen A, Houen G.
PLoS One. 2016 Dec;11(12):e0168542. Pubmed abstract

Intelligence in young adulthood and cause-specific mortality in the Danish Conscription Database – A cohort study of 728,160 men.
Christensen GT, Mortensen EL, Christensen K, Osler M.
Intelligence.  2016 Nov-Dec;59:64-71.  

The emergence of longevous populations.
Colchero F, Rau R, Jones OR, Barthold JA, Conde DA, Lenart A, Nemeth L, Scheuerlein A, Schoeley J, Torres C, Zarulli V, Altmann J, Brockman DK, Bronikowski AM, Fedigan LM, Pusey AE, Stoinski TS, Strier KB, Baudisch A, Alberts SC, Vaupel JW.
Proc Natl Acad Sci U S A. 2016 Nov;113(48):E7681-E7690. Pubmed abstract

Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins.
Starnawska A, Tan Q, Lenart A, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.
Neurobiol Aging. 2016 Nov 4;50:60-63. Pubmed abstract

Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study.
Svendsen AJ, Gervin K, Lyle R, Christiansen L, Kyvik K, Junker P, Nielsen C, Houen G, Tan Q.
Front Immunol. 2016 Nov;7:510. Pubmed abstract

The U-shaped association of body mass index with mortality: Influence of the traits height, intelligence, and education.
Jørgensen TS, Osler M, Ängquist LH, Zimmermann E, Christensen GT, Sørensen TI.
Obesity (Silver Spring). 2016 Oct;24(10):2240-7. Pubmed abstract

Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.
Matthaei J, Tzvetkov MV, Gal V, Sachse-Seeboth C, Sehrt D, Hjelmborg JB, Hofmann U, Schwab M, Kerb R, Brockmöller J.
Genome Med. 2016 Nov 8;8(1):119. Pubmed abstract

Intrapair Comparison of Life-Course Appetite and Physical Activity in Elderly Danish Twins: Reliability and Association With Subsequent Survival.
Løkkegaard LE, Larsen LA, Christensen K.
Twin Res Hum Genet. 2016 Oct;19(5):447-55. Pubmed abstract 

Somatically acquired structural genetic differences: a longitudinal study of elderly Danish twins.
Magaard Koldby K, Nygaard M, Christensen K, Christiansen L.
Eur J Hum Genet. 2016 Oct;24(10):1506-10. Pubmed abstract

Psychosocial health and well-being among obstetricians and midwives involved in traumatic childbirth.
Schrøder K, Larsen PV, Jørgensen JS, Hjelmborg JV, Lamont RF, Hvidt NC.
Midwifery. 2016 Oct;41:45-53. Pubmed abstract

Effect of insulin analogues on frequency of non-severe hypoglycaemia in patients with type 1 diabetes prone to severe hypoglycaemia: The HypoAna trial.
Agesen RM, Kristensen PL, Beck-Nielsen H, Nørgaard K, Perrild H, Christiansen JS, Jensen T, Hougaard P, Parving HH, Thorsteinsson B, Tarnow L, Pedersen-Bjergaard U.
Diabetes Metab. 2016 Sep;42(4):249-55. Pubmed abstract

Changes in cause-specific mortality among the elderly in Canada, 1979-2011.
Bergeron-Boucher MP, Bourbeau R, Légaré.
Canadian Studies in Population 2016;43(3-4):215-233. Online version

Estimating the Impact of Education on Political Participation: Evidence from Monozygotic Twins in the United States, Denmark and Sweden.
Dinesen PT, Oskarsson S, Klemmensen R, Nørgaard AS, Petersen I, Dawes C.
Political Behavior 2016 Sep;38(3):579-601. Online version

How to assess intra- and inter-observer agreement with quantitative PET using variance component analysis: a proposal for standardisation.
Gerke O, Vilstrup MH, Segtnan EA, Halekoh U, Høilund-Carlsen PF.
BMC Med Imaging. 2016 Sep 21;16(1):54. Pubmed abstract

Longitudinal Investigation into Genetics in the Conservation of Metabolic Phenotypes in Danish and Chinese Twins.
Li S, Kyvik KO, Duan H, Zhang D, Pang Z, Hjelmborg JB, Tan Q, Kruse T, Dalgård C.
PLoS One. 2016 Sep 12;11(9):e0162805. Pubmed abstract

Genetic Variants in KLOTHO Associate With Cognitive Function Among the Oldest Old.
Mengel-From J, Soerensen M, Nygaard M, McGue M, Christensen K, Christiansen L
J Gerontol A Biol Sci Med Sci. 2016 Sep;71(9):1151-9. Pubmed abstract

Recurrent Primary Spontaneous Pneumothorax is Common Following Chest Tube and Conservative Treatment.
Olesen WH, Lindahl-Jacobsen R, Katballe N, Sindby JE, Titlestad IL, Andersen PE, Licht PB.
World J Surg. 2016. 2016 Sep;40(9):2163-70. Pubmed abstract

Size, longevity and cancer: age structure.
Wensink MJ.
Proc Biol Sci. 2016 Sep;283(1838). Pubmed abstract

Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau.
Hennild DE, Bjerregaard-Andersen M, Joaquím LC, Christensen K, Sodemann M, Beck-Nielsen H, Jensen DM.
BMC Endocr Disord. 2016 Aug;16(1):46. Pubmed abstract

Comprehensive analysis of high-throughput screens with HiTSeekR.
List M, Schmidt S, Christiansen H, Rehmsmeier M, Tan Q, Mollenhauer J, Baumbach J.
Nucleic Acids Res. 2016 Aug 19;44(14):6639-48. Pubmed abstract

Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology.
Sanders JL, Singh J, Minster RL, Walston JD, Matteini AM, Christensen K, Mayeux R, Borecki IB, Perls T, Newman AB; Long Life Family Study Research Group.
J Am Geriatr Soc. 2016 Aug;64(8):1679-83. Pubmed abstract

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study.
Silventoinen K, Hjelmborg Jv, Möller S, Christensen K, Skytthe A, Kyvik KO, Bjerregaard-Andersen M, Beck-Nielsen H, Sodemann M, McGue M et al.
Am J Clin Nutr. 2016 Aug;104(2):371-9. Pubmed abstract

Epigenetic drift in the aging genome: a ten-year follow-up in an elderly twin cohort.
Tan Q, Heijmans BT, Hjelmborg JV, Soerensen M, Christensen K, Christiansen L.
Int J Epidemiol. 2016 Aug;45(4):1146-1158. Pubmed abstract

High heritability of liability to abdominal aortic aneurysms: a population-based twin-study.
Jørgensen TMM, Houlind KC, Christensen K, Lindholt JS, Larsen LA, Green A.
Eur J Vasc End Sur. 2016;52(1):41-46. Online version

Social Factors and Health: Description of a new Norwegian twin study.
Kutschke J, Falch A, Brandt I, Nilsen TS, Jugessur A, Halekoh U, Seeman TE,  Harris JR.
Norsk Epidemiologi 2016; 26 (1-2): 93-102.

Mitral valve regurgitation in twins: Concordance and survival.
Bakkestrøm R, Larsen LA, Møller JE, Videbæk L, Hjelmborg JB, Christensen K.
American Heart Journal. 2016 Jul; 177:51-7. Online version

A century of trends in adult human height.
NCD Risk Factor Collaboration (NCD-RisC).
Bjerregaard P, Bugge A, Christensen K, Eriksen L, Grøntved A, Møller NC, Tarp J, Tolstrup JS.
eLife. 2016 Jul;5. pii: e13410. Pubmed abstract

Genetics: Healthy ageing, the genome and the environment.
Christensen K, McGue M.
Nat Rev Endocrinol. 2016 Jul;12(7):378-80. Pubmed abstract

School performance in cholesteatoma-operated children in Denmark: a nationwide population-based register-study.
Djurhuus BD, Hansen TG, Pedersen JK, Faber CE, Christensen K.
Acta Otolaryngol. 2016 Jul;136(7):663-8. Pubmed abstract

Migraine with aura and risk of silent brain infarcts and white matter hyperintensities: an MRI study.
Gaist D, Garde E, Blaabjerg M, Nielsen HH, Krøigård T, Østergaard K, Møller HS, Hjelmborg J, Madsen CG, Iversen P, Kyvik KO, Siebner HR, Ashina M.
Brain. 2016 Jul;139(Pt 7):2015-23. Pubmed abstract

Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registries.
Kan C, Pedersen NL, Christensen K, Bornstein SR, Licinio J, MacCabe JH, Ismail K, Rijsdijk F.
Mol Psychiatry. 2016 Jul;21(7):903-9. Pubmed abstract

A multi-ethnic genome-wide association study identifies novel loci for nonsyndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q31.
Leslie EJ, Carlson JC, Shaffer JR, Feingold E, Wehby G, Laurie CA, Jain D, Laurie CC, Doheny KF, McHenry T, Resick J, Sanchez C, Jacobs J, Emanuele B, Vieira AR, Neiswanger K, Lidral AC, Valencia-Ramirez LC, Lopez-Palacio AM, Rivera Valencia D, Arcos-Burgos M, Czeizel AE, Field LL, Padilla CD, Cutiongco-de la Paz EM, Deleyiannis F, Christensen K, Munger RG, Lie RT, Wilcox A, Romitti PA, Castilla EE, Mereb JC, Poletta FA, Orioli IM, Carvalho FM, Hecht JT, Blanton SH, Buxó CJ, Butali A, Mossey PA, Adeyemo WL, James O, Braimah RO, Aregbesola BS, Eshete MA, Abate F, Koruyucu M, Seymen F, Ma L, Enríquez de Salamanca J, Weinberg S, Moreno L, Murray JC, Marazita ML.
Hum Mol Genet. 2016 Jul 1;25(13):2862-2872. Pubmed abstract

Association of Psoriasis With the Risk for Type 2 Diabetes Mellitus and Obesity.
Lønnberg AS, Skov L, Skytthe A, Kyvik KO, Pedersen OB, Thomsen SF.
JAMA Dermatol. 2016 Jul;152(7):761-7. Pubmed abstract

Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots.
Staunstrup NH, Starnawska A, Nyegaard M, Christiansen L, Nielsen AL, Børglum A, Mors O.
Clin Epigenetics. 2016 Jul 26;8:81. eCollection 2016. Pubmed abstract

Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X-ray absorptiometry (DXA).
Tinggaard J, Wohlfahrt-Veje C, Husby S, Christiansen L, Skakkebaek NE, Jensen TK, Grandjean P, Main KM, Andersen HR.
Andrology. 2016 Jul;4(4):735-44. Pubmed abstract

Robust de novo pathway enrichment with KeyPathwayMiner 5.
Alcaraz N, List M, Dissing-Hansen M, Rehmsmeier M, Tan Q, Mollenhauer J, Ditzel HJ, Baumbach J.
F1000Res. 2016 Jun;5:1531. Pubmed abstract

Immunochip analysis identifies association of the RAD50/IL13 region with human longevity.
Flachsbart F, Ellinghaus D, Gentschew L, Heinsen FA, Caliebe A, Christiansen L, Nygaard M, Christensen K, Blanché H, Deleuze JF, Derbois C, Galan P, Büning C, Brand S, Peters A, Strauch K, Müller-Nurasyid M, Hoffmann P, Nöthen MM, Lieb W, Franke A, Schreiber S, Nebel A.
Aging Cell. 2016 Jun;15(3):585-8. Pubmed abstract

Danish cohort of monozygotic inflammatory bowel disease twins: Clinical characteristics and inflammatory activity.
Moller FT, Knudsen L, Harbord M, Satsangi J, Gordon H, Christiansen L, Christensen K, Jess T, Andersen V.
World J Gastroenterol. 2016 Jun 7;22(21):5050-9. Pubmed abstract

Evaluating Clinical Practice Guidelines Based on Their Association with Return to Work in Administrative Claims Data.
Roberts ET, DuGoff EH, Heins SE, Swedler DI, Castillo RC, Feldman DR, Wegener ST, Canudas-Romo V, Anderson GF.
Health Serv Res. 2016 Jun;51(3):953-80. Pubmed abstract

Early Discontinuation of Metformin in Individuals Treated with Inhibitors of Transporters of Metformin.
Stage TB, Lee MP, Hallas J, Christensen MM, Brøsen K, Christensen K, Gagne JJ, Pottegård A.
Basic Clin Pharmacol Toxicol. 2016 Jun;118(6):487-95. Pubmed abstract

No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
Soerensen M, Nygaard M, Debrabant B, Mengel-From J, Dato S, Thinggaard M, Christensen K, Christiansen L.
Exp Gerontol. 2016 Jun;78:57-61. Pubmed abstract

A short leucocyte telomere length is associated with development of insulin resistance.
Verhulst S, Dalgård C, Labat C, Kark JD, Kimura M, Christensen K, Toupance S, Aviv A, Kyvik KO, Benetos A.
Diabetologia. 2016 Jun;59(6):1258-65. Pubmed abstract

Interaction between FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages.
Zeng Y, Chen H, Ni T, Ruan R, Nie C, Liu X, Feng L, Zhang F, Lu J, Li J, Li Y, Tao W, Gottschalk W, Lutz M, Land K, Yashin AI, Tan Q, Yang Z, Bolund L, Qi M, Yang H, Min J, Willcox CD, Willcox B, Gu J, Hauser E, Tian XL, Vaupel JW.
Rejuvenation Res. 2016 Jun;19(3):195-203. Pubmed abstract

Cholesteatoma in Children: Occurence and Risk factors
Bjarki Ditlev Djurhuus.
Ph.d. afhandling. May 2016. 

Psychiatric Diagnoses in Individuals with Non-Syndromic Oral Clefts: A Danish Population-Based Cohort Study.
Pedersen DA, Wehby GL, Murray JC, Christensen K.
PLoS One. 2016 May 25;11(5):e0156261. Pubmed abstract

Molecular characterization of clear cell renal cell carcinoma identifies CSNK2A1, SPP1 and DEFB1 as promising novel prognostic markers.
Rabjerg M, Bjerregaard H, Halekoh U, Jensen BL, Walter S, Marcussen N.
APMIS. 2016 May;124(5):372-383. Pubmed abstract

Comparison of non-parametric methods for ungrouping coarsely aggregated data.
Rizzi S, Thinggaard M, Engholm G, Christensen N, Johannesen TB, Vaupel JW, Lindahl-Jacobsen R.
BMC Med Res Methodol. 2016 May 23;16(1):59. Pubmed abstract

Educational differentials in disability vary across and within welfare regimes: a comparison of 26 European countries in 2009.
Cambois E, Solé-Auró A, Brønnum-Hansen H, Egidi V, Jagger C, Jeune B, Nusselder WJ, Van Oyen H, White C, Robine JM.
J Epidemiol Community Health. 2016 Apr;70(4):331-8.  Pubmed abstract

Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.
Druley TE, Wang L, Lin SJ, Lee JH, Zhang Q, Daw EW, Abel HJ, Chasnoff SE, Ramos EI, Levinson BT, Thyagarajan B, Newman AB, Christensen K, Mayeux R, Province MA.
BMC Geriatr. 2016 Apr 9;16(1):80. Pubmed abstract

Does physical activity moderate the relationship between depression symptomatology and low back pain? Cohort and co-twin control analyses nested in the longitudinal study of aging Danish twins (LSADT)
Hübscher M, Hartvigsen J, Fernandez M, Christensen K, Ferreira P.
Eur Spine J. 2016 Apr;25(4):1226-33. Pubmed abstract

A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.
Leslie EJ, Liu H, Carlson JC, Shaffer JR, Feingold E, Wehby G, Laurie CA, Jain D, Laurie CC, Doheny KF, McHenry T, Resick J, Sanchez C, Jacobs J, Emanuele B, Vieira AR, Neiswanger K, Standley J, Czeizel AE, Deleyiannis F, Christensen K, Munger RG, Lie RT, Wilcox A, Romitti PA, Field LL, Padilla CD, Cutiongco-de la Paz EM, Lidral AC, Valencia-Ramirez LC, Lopez-Palacio AM, Valencia DR, Arcos-Burgos M, Castilla EE, Mereb JC, Poletta FA, Orioli IM, Carvalho FM, Hecht JT, Blanton SH, Buxó CJ, Butali A, Mossey PA, Adeyemo WL, James O, Braimah RO, Aregbesola BS, Eshete MA, Deribew M, Koruyucu M, Seymen F, Ma L, de Salamanca JE, Weinberg SM, Moreno L, Cornell RA, Murray JC, Marazita ML.
Am J Hum Genet. 2016 Apr;98(4):744-54. Pubmed abstract

Rise, stagnation, and rise of Danish women's life expectancy.
Lindahl-Jacobsen R, Rau R, Jeune B, Canudas-Romo V, Lenart A, Christensen K, Vaupel JW.
Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4015-20. Pubmed abstract

Expression and prognostic value of the WEE1 kinase in gliomas.
Music D, Dahlrot RH, Hermansen SK, Hjelmborg J, de Stricker K, Hansen S, Kristensen BW.
J Neurooncol. 2016 Apr;127(2):381-9. Pubmed abstract

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants.
NCD Risk Factor Collaboration (NCD-RisC). Christensen K et al.
Lancet. 2016 Apr;387(10026):1377-96. Pubmed abstract

Change in Depression Symptomatology and Cognitive Function in Twins: A 10-Year Follow-Up Study.
Petersen I, McGue M, Tan Q, Christensen K, Christiansen L.
Twin Res Hum Genet.2016 Apr;19(2):104-11. Pubmed abstract

Efficacy and safety of fosaprepitant for the prevention of nausea and emesis during 5 weeks of chemoradiotherapy for cervical cancer (the GAND-emesis study): a multinational, randomised, placebo-controlled, double-blind, phase 3 trial.
Ruhlmann CH, Christensen TB, Dohn LH, Paludan M, Rønnengart E, Halekoh U, Hilpert F, Feyer P, Kristensen G, Hansen O, Keefe D, Herrstedt J.
Lancet Oncol. 2016 Apr;17(4):509–18. Pubmed abstract

Differentially Methylated Genomic Regions in Birth-Weight Discordant Twin Pairs.
Chen M, Baumbach J, Vandin F, Röttger R, Barbosa E, Dong M, Frost M, Christiansen L, Tan Q.
Ann Hum Genet. 2016 Mar;80(2):81-7. Pubmed abstract

A Danish Twin Study of Schizophrenia Liability: Investigation from Interviewed Twins for Genetic Links to Affective Psychoses and for Cross-Cohort Comparisons.
Kläning U, Trumbetta SL, Gottesman II, Skytthe A, Kyvik KO, Bertelsen A.
Behav Genet. 2016 Mar;46(2):193-204. Pubmed abstract

A Twin Study of Perthes Disease.
Metcalfe D, Van Dijck S, Parsons N, Christensen K, Perry DC.
Pediatrics. 2016 Mar;137(3):1-5. Pubmed abstract

Association between the surfactant protein D (SFTPD) gene and subclinical carotid artery atherosclerosis.
Sorensen GL, Bladbjerg EM, Steffensen R, Tan Q, Madsen J, Drivsholm T, Holmskov U.
Atherosclerosis. 2016 Mar;246:7-12. Pubmed abstract

 Health and function assessments in two adjacent Danish birth cohorts of centenarians: Impact of design and methodology.
Vestergaard S, Andersen-Ranberg S, Skytthe A, Christensen K, Robine JM, Jeune B.
European Journal of Ageing. 2016 Mar;13(1):15-23.

The association between intelligence and lifespan is mostly genetic.
Arden R, Luciano M, Deary IJ, Reynolds CA, Pedersen NL, Plassman BL, McGue M, Christensen K, Visscher PM.
Int J Epidemiol. 2016 Feb;45(1):178-85. Pubmed abstract

Young adults intelligence and mortality - epidemiological studies based on the Danish Conscription Database.
Gunhild Tidemann Christensen.
Ph.d. afhandling. Feb 2016. 

DNA methylation age is associated with mortality in a longitudinal Danish twin study.
Christiansen L, Lenart A, Tan Q, Vaupel JW, Aviv A, McGue M, Christensen K.
Aging Cell. 2016 Feb;15(1):149-54. Pubmed abstract

Cognitive Functioning after Surgery in Middle-aged and Elderly Danish Twins.
Dokkedal U, Hansen TG, Rasmussen LS, Mengel-From J, Christensen K.
Anesthesiology. 2016 Feb;124(2):312-21. Pubmed abstract

Leucocyte Telomere Length and Risk of Cardiovascular Disease in a Cohort of 1,397 Danish Men and Women.
Ellehoj H, Bendix L, Osler M.
Cardiology. 2016 Feb;133(3):173-7. Pubmed abstract

Opposite-sex twins - Academic performance, religiousness, cancer, and mortality.
Linda Juel Ahrenfeldt.
Ph.d. afhandling. Feb 2016. 

Differences in religiousness in opposite-sex and same-sex twins in a secular society.
Juel Ahrenfeldt L, Lindahl-Jacobsen R, Möller S, Christensen K, Hvidtjørn D, Hvidt NC.
Twin Res Hum Genet. 2016 Feb;19(1):35-46.  Pubmed abstract

Genetic and Environmental Regulation on Longitudinal Change of Metabolic Phenotypes in Danish and Chinese Adult Twins.
Li S, Kyvik KO, Pang Z, Zhang D, Duan H, Tan Q, Hjelmborg J, Kruse T, Dalgård C.
PLoS One. 2016 Feb;11(2):e0148396. Pubmed abstract

Smoking and risk for psoriasis: a population-based twin study.
Lønnberg AS, Skov L, Skytthe A, Kyvik KO, Pedersen OB, Thomsen SF.
Int J Dermatol. 2016 Feb;55(2):e72-8. Pubmed abstract

Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment.
Nygaard M, Debrabant B, Tan Q, Deelen J, Andersen-Ranberg K, de Craen AJ, Beekman M, Jeune B, Slagboom PE, Christensen K, Christiansen L.
Aging Cell. 2016 Feb;15(1):49-55. Pubmed abstract

Sex differences in risk and heritability estimates on primary knee osteoarthritis leading to total knee arthroplasty: a nationwide population based follow up study in Danish twins.
Skousgaard SG, Skytthe A, Möller S, Overgaard S, Brandt LP.
Arthritis Res Ther. 2016 Feb ;18:46. Pubmed abstract

Application of synthetic peptides for detection of anti-citrullinated peptide antibodies.
Trier NH, Holm BE, Slot O, Locht H, Lindegaard H, Svendsen A, Nielsen CT, Jacobsen S, Theander E, Houen G.
Peptides. 2016 Feb;76:87-95. Pubmed abstract

Novel loci and pathways significantly associated with longevity.
Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, Yan H, Zhang JP, Song C, Chi LQ, Wang HM, Dong J, Zheng GY, Lin L, Qian F, Qi Y, Liu X, Cao H, Wang Y, Zhang L, Li Z, Zhou Y, Wang Y, Lu J, Li J, Qi M, Bolund L, Yashin A, Land KC, Gregory S, Yang Z, Gottschalk W, Tao W, Wang J, Wang J, Xu X, Bae H, Nygaard M, Christiansen L, Christensen K, Franceschi C, Lutz MW, Gu J, Tan Q, Perls T, Sebastiani P, Deelen J, Slagboom E, Hauser E, Xu H, Tian XL, Yang H, Vaupel JW.
Sci Rep. 2016 Feb 25;6:21243. Pubmed abstract

Homicides in Mexico Reversed Life Expectancy Gains for Men and Slowed them for Women.
Aburto JM, Beltran-Sanchex H, Garcia-Guerrero VM, Canudas-Romo V.
Health Affairs. 2016 Jan;35(1):88-95.

Optimal Versus Realized Trajectories of Physiological Dysregulation in Aging and Their Relation to Sex-Specific Mortality Risk.
Arbeev KG, Cohen AA, Arbeeva LS, Milot E, Stallard E, Kulminski AM, Akushevich I, Ukraintseva SV, Christensen K, Yashin AI.
Front Public Health. 2016 Jan;4:3. Pubmed abstract

Trends in cancer in the elderly population in Denmark, 1980-2012.
Ewertz M, Christensen K, Engholm G, Kejs AM, Lund L, Matzen LE, Pfeiffer P, Storm HH, Herrstedt J; Academy of Geriatric Cancer Research (AgeCare).
Acta Oncol. 2016 Jan;55 Suppl 1:1-6. Pubmed abstract

Mortality is Written on the Face.
Gunn DA, Larsen LA, Lall JS, Rexbye H, Christensen K.
J Gerontol A Biol Sci Med Sci. 2016 Jan;71(1):72-7.  Pubmed abstract

New light on Roman census papyri through semi-linkage automated record.
Hin S, Conde DA, Lenart A.
Historical Methods. 2016 Jan. 49(1): 50-65. Online version

The Liability Threshold Model for Censored Twin Data.
Holst KK, Scheike TH, Hjelmborg JB.
Computational Statistics & Data Analysis 2016 Jan;93(C):324-35. Open assess

Genetic Factors Explain Variation in the Age at Onset of Psoriasis: A Population-based Twin Study.
Lønnberg AS, Skov L, Duffy DL, Skytthe A, Kyvik KO, Pedersen OB, Thomsen SF.
Acta Derm Venereol. 2016 Jan 20;96(1):35-8.  Pubmed abstract

Familial Risk and Heritability of Cancer Among Twins in Nordic Countries.
Mucci LA, Hjelmborg JB, Harris JR, Czene K, Havelick DJ, Scheike T, Graff RE, Holst K, Möller S, Unger RH, McIntosh C, Nuttall E, Brandt I, Penney KL, Hartman M, Kraft P, Parmigiani G, Christensen K, Koskenvuo M, Holm NV, Heikkilä K, Pukkala E, Skytthe A, Adami HO, Kaprio J; Nordic Twin Study of Cancer (NorTwinCan) Collaboration.
JAMA. 2016 Jan 5;315(1):68-76. Pubmed abstract

The Heritability of Breast Cancer among women in the Nordic Twin Study of Cancer.
Möller S, Mucci LA, Harris JR, Scheike T, Holst K, Halekoh U, Adami HO, Czene K, Christensen K, Holm NV, Pukkala E, Skytthe A, Kaprio J, Hjelmborg JB.
Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):145-50. Pubmed abstract

Cancer and aging: Epidemiology and methodological challenges.
Pedersen JK, Engholm G, Skytthe A, Christensen K; Academy of Geriatric Cancer Research (AgeCare).
Acta Oncol. 2016 Jan;55 Suppl 1:7-12. Pubmed abstract

GxE Interaction Influences Trajectories of Hand Grip Strength.
Petersen I, Pedersen NL, Rantanen T, Kremen WS, Johnson W, Panizzon MS, Christiansen L, Franz CE, McGue M, Christensen K, Hamdi NR, Krueger RF, Reynolds C.
Behav Genet. 2016 Jan;46(1):20-30. Pubmed abstract

Prayer and meditation among Danish first time mothers-a questionnaire study.
Prinds C, Hvidtjørn D, Skytthe A, Mogensen O, Hvidt NC.
BMC Pregnancy Childbirth. 2016;16(1):8. Pubmed abstract

Gene-Environment Interplay in Physical, Psychological, and Cognitive Domains in Mid to Late Adulthood: Is APOE a Variability Gene?
Reynolds CA, Gatz M, Christensen K, Christiansen L, Dahl Aslan AK, Kaprio J, Korhonen T, Kremen WS, Krueger R, McGue M, Neiderhiser JM, Pedersen NL; IGEMS consortium.
Behav Genet. 2016 Jan;46(1):4-19. Pubmed abstract

Survival Prognosis in Very Old Adults.
Thinggaard M, McGue M, Jeune B, Osler M, Vaupel JW, Christensen K.
J Am Geriatr Soc. 2016 Jan;64(1):81-8. Pubmed abstract

Remaining Life Expectancy With and Without Polypharmacy: A Register-Based Study of Swedes Aged 65 Years and Older.
Wastesson JW, Canudas-Romo V, Lindahl-Jacobsen R, Johnell K.
J Am Med Dir Assoc. 2016 Jan 1;17(1):31-5. Pubmed abstract

Post-War Migration Flows and Disparities in Mortality from Age 50 Years Onwards: the Case of Turin in Italy.
Zarulli V.
Population, Space and Place. Jan 2016;22(1):54-67.

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