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Pharmacoepidemiology

Often, it is attempts to answer the clinical pharmacological questions by using epidemiological methods.

An important tool in the units pharmacoepidemiological research is the Odense pharmacoepidemiological database, (OPED) which was established in 1990. OPED is a complete database containing all medicine for the inhabitants of the county of Funen, the database is directly referable to the patients.

OPED has offered new possibilities to describe the patterns in the drug use qualitatively, to describe the drug effects and to focus and monitor interventions.

It has founded a reliable work basis for the local research units within clinical pharmacology, general practice, biostatistics and health economics. Throughout the years, the working relationship amongst these groups has been very good. In 2007, the database was extended to include the entire Region of South Denmark and in 2009 the Region of Zealand. With this extension, the total of participants in this database will reach 2 million people. In contrast to the national drug register, which is under the auspices of Statistics Denmark, there is a possibility to identify concrete drug users and to contact them regarding further information.

Qualifications

The department has been working scientifically and published within the following areas of pharmacoepidemiological methodology:
Intensive monitoring of adverse drug events
Intervention studies regarding prescription behavior
Health Economics
Descriptive analyses of drug use

  • Individually based statistics over drug use
  • Quality predictors
  • Waiting time analyses

Causality enquiring studies

  • Cohort studies
  • Case-control studies
  • Symmetry analyses
  • Other advanced epidemiological designs
  • Stream-lined clinical trials

Key Publications

Focus points

Pharmacoepidemiological aspects within the following clinical disciplins:

  • General Practice
  • Gastroenterology
  • Respiratory medicine
  • Neurology
  • Oncology

Quality predictors in drug use

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