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Design and analysis of epigenome-wide association studies

Graduate Programme in Public Health

Contents:
The etiology of complex diseases concerns not only the DNA sequence variation of a gene, but most importantly also the functional regulation of the gene triggered by specific environmental stimuli. Epigenetics is a newly emerging field of genetic study that focuses on the dynamic aspects of gene activity regulation under given environmental conditions, a very hot topic in many areas of medical research. This course focuses on the design and analysis of epigenomic studies using high-throughput microarray technology with issues concerning study design, biosample collection, data preprocessing, normalization, quality control, statistical and bioinformatic analyses, biological pathway-based analysis and functional interpretation. Students are introduced to the cutting-edge development in epigenetic analysis of human diseases and learn about epigenomic data structure, state-of-the-art data analysis with multiple free software packages.

Aim:
The aim of the course is to learn the cutting-edge techniques for analyzing and interpreting data collected in epigenomic studies.

Course credit: 3,2 ECTS

Programme

Teaching arrangement: Lecturing and exercises

Course leader: Qihua Tan, University of Southern Denmark

Course Teachers: Qihua Tan, Jacob Hjelmborg, Lene Christiansen & Ulrich Halekoh - all from the University of Southern Denmark

Place: University of Southern Denmark, Odense

Max number of participants: 15 PhD students

Course Fee:
The course is free of charge for PhD students enrolled in Universities that have joined the "Open market agreement".
For other participants there is a course fee of DKK 8373,-

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