The honours class consists of one course (20 ECTS).
In the course, you will focus on:
- Molecular genetics for the diagnosis of inherited diseases (PCR in relation to mutation-specific and general mutation scanning assays. DNA sequencing)
- Chromosome analysis (microscopy and molecular cytogenetics).
- Methods for detection of disease markers – e.g. metabolites – in plasma and tissue (immune assays, chromatography and mass spectrometry, spectrophotometry and flow cytometry)
- Detection and characterisation of disease causing microorganisms (DNA sequencing and Real-time PCR).
- Method for bio-imaging (PET scanning/radioactive tracer and MR scanning).
- Methods for characterisation of gene expression (micro arrays and quantitative PCR).
- Quality control, validation, sources of variation, specificity and sensitivity in relation to molecular disease diagnostics.
- Automation and high throughput screening.
- Search in sequence, disease and syndrome databases
- Ethics in relation to genetic counselling.