SPSE Publications
The following scientific contributions are representatve of the kind of recent work on which the Center is based.
Microparticle and Interfacial Studies
- S. Lee, D. H. Kim, and D. Needham. (2001) Static and Dynamic Surface Tension Measurement of Microscopic Interfaces Using a Micropipet Technique: 1. A New Method for Determination of Surface Tension, Langmuir 2001, 17, 5537-5543.
- S. Lee, D. H. Kim, and D. Needham. (2001) Static and Dynamic Surface Tension Measurement of Microscopic Interfaces Using a Micropipet Technique: 2. Dynamics of Phospholipid Monolyer Formation and Equilibrium Spreading Pressures at the Air-Water Interface, Langmuir 2001, 17, 5544-5550
- D. H. Kim, M, J. Costello, P. B. Duncan and D. Needham, (2003). Mechanical properties and microstructure of polycrystalline phospholipid monolayer shells - novel solid nanoparticles, Langmuir, 19, 8455-8466
- P. Duncan and D. Needham, (2004). Test of the Epstein-Plesset Model for Gas Microparticle Dissolution in Aqueous Media: Effect of Surface Tension and Gas Undersaturation in Solution. Langmuir; 20(7); 2567-2578.
- P. Duncan and D. Needham, Microdroplet dissolution into a second-phase solvent using a micropipet technique: Test of the Epstein-Plesset model for an aniline-water system (2006), Langmuir, 22 Issue: 9 Pages: 4190-4197
- S. I. Simon, K. Florine-Casteel, K. Ritchie, H.P. Ting-Beall, E. Evans, and D. Needham, (2007). Dynamics of Neutrophil Membrane Compliance and Microstructure probed with a Micropipet-based Piconewton Force Transducer, Annals Biomed Egr. Volume 35, Number 4 / April, 2007, 595-604
- M. Holden, D. Needham, H Bayley, (2007). Functional Bio-Networks from Nanoliter Water Droplets J. Am Chem Soc., vol. 129, pp. 8650-8655
- Chiming Yang, David Plackett, David Needham , Helen M. Burt (2009) PLGA and PHBV microsphere formulations and solid-state characterization: Local delivery of fusidic acid for the treatment and prevention of orthopaedic infections, Pharmaceutical Research, Vol. 26, No. 7.
- Jonathan T Su, David Needham, (2010) The Effects of Hydrogen Bonding on the Diffusion of Water in n-Alkanes and n-Alcohols Measured with a Novel Single Microdroplet Method, J. Chem Phys Volume: 132 Issue: 4 Page: 044506,
- Deborah L Rickard, Brent Duncan and David Needham, (2010). Hydration Potential of Lysozyme: Protein Dehydration Using a Single Microparticle Technique, Biophysical Journal, Volume 98, Issue 6, 17 March 2010, Pages 1075-1084
- David Needham, (2011). Lipid structures: A brief history of multisomes, Nature Nanotechnology , News and Views 6, 761–762, Published online, 06 December 2011.
- Samuel E. Gilchrist, Deborah L. Rickard, Kevin Letchford, David Needham & Helen M. Burt (2012). The phase separation behavior of fusidic acid and rifampicin in PLGA microspheres, published on line, Molecular Pharmaceutics. DOI: 10.1021/mp300099f • Publication Date (Web): 07 Apr 2012.
- David Needham, (2012). Micropipette Manipulation of Lipid Bilayer Membranes, Encyclopedia of Biophysics, Springer http://www.springerreference.com/docs/html/chapterdbid/332494.html.
Recent Drug Delivery Publications (Therml Sensitive Liposome)
- Yarmolenko PS, Zhao Y, Landon C, Spasojevic I, Yuan F, Needham D, Viglianti BL, Dewhirst MW. (2010). Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumors. Int J Hyperthermia. 2010;26(5):485-98. Times Cited: 16
- Grant, GA, Wilson, C, Salami, S, Macaroni, P, Li, SQ, Park, JY, Needham, D, Bigner, D Dewhirst, MW., PRECLINICAL USE OF MILD HYPERTHERMIA TO ENHANCE DRUG DELIVERY TO BRAIN TUMORs, NEURO-ONCOLOGY Volume: 13 Supplement: 3 Pages: 111-111: NOV 2011
- C. Landon, J.Y. Park, D. Needham, and M. W. Dewhirst, (2011). Nano-Encapsulation Technology for Drug Delivery, in "Therapeutic Approaches and Drug Delivery", The Open Nanomedicine Journal, 2011, 3, 38-64, Wiley Interdisciplinary Reviews: Nanomedicine & Nanobiotechnology, John Wiley & Sons, Inc.
- D. Needham and M. W. Dewhirst, (2012), Materials Science and Engineering of the Low Temperature Sensitive Liposome (LTSL): Composition-Structure-Property Relationships that Underlie its Design and Performance, (Chapter 2). In “Smart Materials for Drug Delivery”, Carmen Alvarez-Lorenzo and Angel Concheiro Eds, Royal Society of Chemistry, Publishing.
- Ashley A. Manzoor, Lars H. Lindner, Ji-Young Park, Andrew J. Simnick, Matthew R. Dreher, Shiva Das, Gabi Hanna, Won Park, Gerben Koning, Timo ten Hagen, David Needham, Mark W. Dewhirst, (2012). Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors, Cancer Research doi:10.1158/0008-5472.CAN-12-1683.
- Ryan M Davis, Benjamin L Viglianti, Pavel Yarmolenko, Paul Stauffer, Ji-Young Park, Paolo Maccarini, David Needham, Mark W Dewhirst. (2012). Simultaneously monitoring tumor temperature and temperature sensitive liposome content release with MRI, in review Int. J. Hyperthermia
- David Needham, Ji-Young Park, Alexander M. Wright, Jihong Tong (2012). Materials Characterization of the Low Temperature Sensitive Liposome (LTSL): Effects of Lipid Composition (Lysolipid and DSPE-PEG2000) on the Thermal Transition and Release of Doxorubicin. Faraday Discussions Faraday Discussion 161: Lipids and Membrane Biophysics Accepted manuscript, DOI: 10.1039/C2FD20111A