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Publikationer: 2000-09

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2009

Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D et al.
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
Nat Genet. 2009; (1), 47-55. Pubmed abstract

Barbieri M, Paolisso G, Kimura M, Gardner JP, Boccardi V, Papa M, Hjelmborg JvB, Christensen K, Brimacombe M, Nawrot TS, Staessen JA, Pollak MN, Aviv A.
Higher circulating levels of IGF-1 are associated with longer leukocyte telomere length in healthy subjects.
Mech Ageing Dev. 2009 Nov-Dec;130(11-12):771-6. Pubmed abstract

Brix TH, Hansen PS, Knudsen GPS, Kringen MK, Kyvik KO, Ørstavik KH, Hegedüs L.
No link between X chromosome inactivation pattern and simple goiter in females. Evidence from a twin study.
Thyroid. 2009;19(2),165-9. Pubmed abstract

Brix TH, Hansen PS, Kyvik KO, Hegedüs L.
Aggregation of thyroid autoantibodies in twins from opposite-sex pairs suggests that microchimerism may play a role in the early stages of thyroid autoimmunity.
J Clin Endocrinol Metab. 2009 Nov;94(11):4439-43. Pubmed abstract

Brix TH, Hansen PS, Bennedbæk FN, Bonnema SJ, Kyvik KO, Orstavik KH, Hegedüs L.
X chromosome inactivation pattern is not associated with interindividual variations in thyroid volume: A study of euthyroid Danish female twins.
Twin Res Hum Genet. 2009 Oct; 12(5): 502-506. Pubmed abstract

Christiansen L, Tan Q, Kruse TA, McGue M, Christensen K.
Candidate region linkage analysis in twins discordant or concordant for depression symptomatology.
Am J Med Genet B Neuro Genet. 2009;150B(4), 581-4. Pubmed abstract

Christensen K, Thinggaard M, McGue M, Rexbye H, Hjelmborg JvB, Aviv A, Gunn D, V d Ouderaa F, Vaupel JW.
Perceived age is a clinically useful biomarker of ageing: Cohort study.
BMJ. 2009 Dec 10;339:b5262. Pubmed abstract

Christophersen IE, Ravn LS, Budtz-Joergensen E, Skytthe A, Haunsoe S, Svendsen JH, Christensen K.
Familial aggregation of atrial fibrillation: A study in Danish twins.
Circ Arrhythm Electrophysiol. 2009 Aug; 2(4):378-83. Pubmed abstract

Corey LA, Kjeldsen MJ, Solaas MH, Nakken KO, Friis ML, Pellock JM.
The accuracy of self-reported history of seizures in Danish, Norwegian and U.S. twins.
Epilepsy Res. 2009 Mar; 84(1):1-5. Pubmed abstract

Douglas RS, Brix TH, Hwang CJ, Hegedüs L, Smith TJ.
Divergent frequencies of IGF-I receptor-expressing blood lymphocytes in monozygotic twin pairs discordant for Graves' disease: Evidence for a phenotypic signature ascribable to nongenetic factors.
J Clin Endocrinol Metab. 2009 May; 94(5):1797-802. Pubmed abstract

Elberling J, Lerbaek A, Kyvik KO, Hjelmborg J.
A twin study of perfume-related respiratory symptoms.
Int J Hyg Environ Health. 2009 Nov;212(6):670-8. Pubmed abstract

Fraser A, Thinggaard M, Christensen K, Lawlor DA.
Alanine aminotransferase, gamma-glutamyltransferase (GGT) and all-cause mortality: Results from a population-based Danish twins study alanine aminotransferase, GGT and mortality in elderly twins.
Liver Int. 2009 Nov; 29(10): 1494-9. Pubmed abstract

Frokjaer VG, Vinberg M, Erritzoe D, Svarer C, Baaré W, Budtz-Joergensen E, Madsen K, Madsen J, Kessing LV, Knudsen GM.
High familial risk for mood disorder is associated with low dorsolateral prefrontal cortex serotonin transporter binding.
Neuroimage. 2009 Jun;46(2):360-6. Pubmed abstract

Hartvigsen J, Nielsen J, Kyvik KO, Fejer R, Vach W, Iachine I, Leboeuf-Yde C.
Heritability of spinal pain and consequences of spinal pain: A comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20-71 years.
Arthritis Rheum. 2009 Oct 15; 61(10): 1343-51. Pubmed abstract

Johnson W, Deary IJ, McGue M, Christensen K.
Genetic and environmental links between cognitive and physical functions in old age.
J Gerontol B Psych Sci Soc Sci. 2009;64(1), 65-72. Pubmed abstract

Johnson W, Deary IJ, McGue M, Christensen K.
Genetic and environmental transactions linking cognitive ability, physical fitness, and education in late life.
Psych Aging. 2009;24(1), 48-62. Pubmed abstract

Kettunen J, Perola M, Martin NG, Visscher PM, Montgomery GW, Benyamin B, Harris JR, Boomsma D, Willemsen G, Hottenga J-J, Christensen K, Kyvik KO, Sørensen TIA, Pedersen N, Magnusson PKE, Spector TD, Widen E, Silventoinen K, Kaprio J, Palotie A, Peltonen L , for the GenomEUtwin – project.
Combined linkage scan of body mass index in European-originated twin-cohort.
Int J Obes (Lond). 2009 Nov;33(11):1235-42.

Kimani JW, Yoshiura K, Shi M, Jugessur A, Moretti-Ferreira D, Christensen K, Murray JC.
Search for genomic alterations in monozygotic twins discordant for cleft lip and/or palate.
Twin Res Human Genet. 2009;12(5):462-8.

Kulminski AM, Arbeev KG, Culminskaya IV, Ukraintseva SV, Christensen K, Yashin AI.
Health-related phenotypes and longevity in Danish twins.
J Gerontol A Biol Sci Med Sci. 2009;64(1), 1-8. Pubmed abstract

Lorenz D, Klebe S, Stevanin G, Thier S, Nebel A, Feingold J, Frederiksen H, Denis E, Christensen K, Schreiber S, Brice A, Deuschl G, Dürr A.
Dopamine receptor D3 gene and essential tremor in large series of German, Danish and French patients.
Eur J Hum Genet. 2009; (6), 766-73. Pubmed abstract

Leboeuf-Yde C, Nielsen J, Kyvik KO, Fejer R, Hartvigsen J.
Pain in the lumbar, thoracic or cervical regions: Do age and gender matter? A population-based study of 34,902 Danish twins 20-71 years of age.
BMC Muscul Dis. 2009 Apr 20; 10:39. Pubmed abstract

McEvoy BP, Montgomery GW, McRae AF, Ripatti S, Perola M, Spector TD, Cherkas L, Ahmadi KR, Boomsma D, Willemsen G, Pedersen NL, Magnusson PKE, Kyvik KO, Christensen K, Kaprio J, Heikkilä K, Palotie A, Widen E, Muilu J, Syvänen A-C, Liljedahl U, Hardiman O, Cronin S, Peltonen L, Martin NG, Visscher PM.
Geographical structure and differential natural selection amongst North European populations.
Genome Res. 2009 May;19(5):804-14. Pubmed abstract

Oksuzyan O, Petersen I, Støvring H, Bingley P, Vaupel JW, Christensen K.
The male-female health-survival paradox: A survey and register study of the impact of sex-specific selection and information bias.
Ann Epidemiol. 2009;19(7), 504-511. Pubmed abstract

Osler M, Madsen M, Nybo Andersen AM, Avlund K, McGue M, Jeune B, Christensen K.
Do childhood and adult socioeconomic circumstances influence health and physical function in middle-age?
Soc Sci Med. 2009 Apr;68(8):1425-31. Pubmed abstract

Petersen I, Jensen VM, McGue M, Bingley P, Christensen K.
No evidence of genetic mediation in the association between birthweight and academic performance in 2,413 Danish adolescent twin pairs.
Twin Res Hum Genet. 2009;12(6):564-72.

Silventoinen K, Hasselbalch AL, Lallukka T, Bogl L, Pietiläinen KH, Heitmann BL, Schousboe K, Rissanen A, Kyvik KO, Sørensen TI, Kaprio J.
Modification effects of physical activity and protein intake on heritability of body size and composition.
Am J Clin Nutr. 2009 Oct;90(4):1096-103. Pubmed abstract

Stensballe LG, Simonsen JB, Thomsen SF, Larsen AM, Lysdal SH, Aaby P, Kyvik KO, Skytthe A, Backer V, Bisgaard H.
The causal direction in the association between severe respiratory syncytial virus infection and asthma: A registry-based twin study.
J Allergy Clin Immunol. 2009; Jan; 123(1),131-7. Pubmed abstract

Thomsen SF, Ferreira MA, Kyvik KO, Fenger M, Backer V.
A quantitative genetic analysis of intermediate asthma phenotypes.
Allergy. 2009 Mar; 64(3):427-30. Pubmed abstract

Thomsen SF, Sluis SVD, Stensballe LG, Posthuma D, Skytthe A, Kyvik KO, Duffy DL, Backer V, Bisgaard H. 
Exploring The Association Between Severe Respiratory Syncytial Virus Infection and Asthma: a Registry-Based Twin Study.
Am J Respir Crit Care Med. 2009; 179(12): 1091-7.

van den Berg GJ, Doblhammer G, Christensen K.
Exogenous determinants of early-life conditions, and mortality later in life.
Soc Sci Med. 2009 May; 68(9):1591-8. Pubmed abstract

van der Deure WM, Hansen PS, Peeters RP, Uitterlinden AG, Fenger M, Kyvik KO, Hegedüs L, Visser TJ.
The effect of genetic variation in the type 1 deiodinase gene on the inter-individual variation in serum thyroid hormone levels. An investigation in healthy Danish twins.
Clin Endocrinol (Oxf). 2009 Jun; 70(6):954-60. Pubmed abstract

Vink JM, Smit AB, de Geus EJC, Sullivan P, Willemsen G, Hottenga JJ, Smit J, Hoogendijk W, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Spector TD, Kyvik KO, Morley KI, Heath AC, Westendorp RGJ, Slagboom PE, Tiemeier H, Hofman A, Uitterlinden AG, Aulchenko YS, Amin N, van Duijn C, Penninx BW, Boomsma DI.
Genome-wide association study of smoking initiation and persistence.
Am J Hum Genet. 2009 Mar;84(3):367-79. Pubmed abstract

Williams FM, Carter AM, Kato B, Falchi M, Bathum L, Surdulescu G, Kyvik KO, Palotie A, Spector TD, Grant PJ; on Behalf of the EuroCLOT Investigators.
Identification of Quantitative Trait Loci for Fibrin Clot Phenotypes. The EuroCLOT Study.
Arterioscler Thromb Vasc Biol. 2009;29(4):600-5. Pubmed abstract

2008 -- til toppen --^

Christensen K, McGue M.
Academic achievement in twins.
British Medical Journal 2008 Jul 21; 337:a651 (editorial).

Hartman M, Hall P, Edgren G, Reilly M, Lindstrom L, Lichtenstein P, Kaprio J, Skytthe A, Peto J, Czene K.
Breast cancer onset in twins and women with bilateral disease.
J Clin Oncol 2008;26(25):4086-91. Pubmed abstract

Hasselbalch AL, Benyamin B, Visscher PM, Heitmann BL, Kyvik KO, Sørensen TIA.
Common genetic components of obesity traits and serum leptin level.
Obesity (Silver Spring). 2008 Dec; 16(12); 2723-9. Pubmed abstract

Hasselbalch AL, Heitmann BL, Kyvik KO, Sørensen TIA.
Studies of twins indicate that genetics influence dietary intake.

J Nutr. 2008 Dec;138(12):2406-2412. Pubmed abstract

Hestbaek L, Korsholm L, Leboeuf-Yde C, Kyvik KO.
Does socioeconomic status in adolescence predict low back pain in adulthood? A repeated cross-sectional study of 4,771 Danish adolescents.
Eur Spine J. 2008 Dec; 17(12):1727-34. Pubmed abstract

Hjelmborg J, Fagnani C, Silventoinen K, McGue M, Korkeila M, Christensen K, Rissanen A, Kaprio J.
Genetic influences on growth traits of BMI: A longitudinal study of adult twins.
Obesity 2008 Apr;16(4):847-52. Pubmed abstract

Knaapila A, Tuorila H, Silventoinen K, Wright M, Kyvik KO, Cherkas LF, Keskitalo K, Martin NG, Spector TD, Kaprio J, Perola M.
Genetic and environmental contributions to perceived intensity and pleasantness of androstenone odor: An international twin study.
Chem Percept 2008 Jan;1(1): 34-42.

Knaapila A, Tuorila H, Silventoinen K, Wright MJ, Kyvik KO, Keskitalo K, Hansen J, Kaprio J, Perola M.
Environmental effects exceed genetic effects on perceived intensity and pleasantness of several odors: A three-population twin study.
Behav Genet. 2008 Sep;38(5):484-92. Pubmed abstract

Knaapila A, Tuorila H, Wright MJ, Kyvik KO, Cherkas LF, Keskitalo K, Hansen J, Martin NG, Spector TD, Kaprio J, Perola M, Silventoinen K.
Self-ratings of olfactory function reflect odor annoyance rather than olfactory acuity.
The Laryngoscope 2008 Dec. 118: 2212-2217. Pubmed abstract

Kimura M, Cherkas LF, Kato BS, Demissie S, Hjelmborg JB, Brimacombe M, Cupples A, Hunkin JL, Gardner JP, Lu X, Cao X, Sastrasinh M, Province MA, Hunt SC, Christensen K, Levy D, Spector TD, Aviv A.
Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm.
PLoS Genet. 2008 Feb;4(2):e37. Pubmed abstract

Kimura M, Hjelmborg JV, Gardner JP, Bathum L, Brimacombe M, Lu X, Christiansen L, Vaupel JW, Aviv A, Christensen K.
Telomere length and mortality: A study of leukocytes in elderly Danish twins.
Am J Epidimiol 2008 Apr 1;167(7):799-806. Pubmed abstract 

Lerbaek A, Kyvik KO, Ravn H, Menné T, Agner T.
Clinical characteristics and consequences of hand eczema – an eight year follow-up study of a population-based twin cohort.
Contact Dermatitis 2008 Apr;58(4):210-6. Pubmed abstract

Lorenz D, Papengut F, Frederiksen H, Kopper F, Klebe S, Christensen K, Schreiber S, Deuschl G.
Evaluation of a screening instrument for essential tremor.
Movement Disorders 2008 May 15;23(7):1006-12. Pubmed abstract 

Osler M, McGue M, Lund R, Christensen K.
Marital status and twins' health and behavior: An analysis of middle-aged Danish twins.
Psychosomatic Medicine 2008 May; 70(4):482-7. Pubmed abstract

Pedersen LM, Pedersen TA, Herskind AM.
Multipel graviditet hos kvinder med korrigeret Steno-Fallots tetralogi
[Multiple pregnancies in women with corrected tetralogy of Fallot]
Ugeskr Laeger 2008 Oct 20;170(43):3436. Pubmed abstract

Pedersen OB, Svendsen AJ, Ejstrup L, Skytthe A, Harris JR, Junker P.
Ankylosing spondylitis in Danish and Norwegian twins: Occurrence and the relative importance of genetic vs. environmental effectors in disease causation.
Scand J Rheumatol. 2008;37(2):120-6. Erratum in: Scand J Rheumatol. 2008;37(5):400. Pubmed abstract

Pedersen OB, Svendsen AJ, Ejstrup L, Skytthe A, Junker P.
On the heritability of psoriatic arthritis. Disease concordance among monozygotic and dizygotic twins.
Ann Rheum Dis. 2008 Oct;67(10):1417-21. Pubmed abstract

Pedersen OB, Svendsen AJ, Ejstrup L, Skytthe A, Junker P.
The occurrence of psoriatic arthritis in Denmark.
Ann Rheum Dis. 2008 Oct;67(10):1422-6. Review. Pubmed abstract

Pinborg LH, Arfan H, Haugbol S, Kyvik KO, Hjelmborg JB, Svarer C, Frokjaer VB, Paulson OG, Holm S, Knudsen GM.
The 5-HT2A receptor binding pattern in the human brain is strongly genetically determined.
Neuroimage. 2008 Apr 15;40(3):1175-80. Pubmed abstract

Rodgers JL, Kohler HP, McGue M, Behrman JR, Petersen I, Bingley P, Christensen K.
Education and cognitive ability as direct, mediating, or spurious influences on female age at first birth: Behaviour genetic models fit to Danish twin data.
AJS. 2008;114 Suppl:S202-32. Pubmed abstract

Schnack TH, Zdravkovic S, Myrup C, Westergaard T, Christensen K, Wohlfahrt J, Melbye M.
Familial aggregation of hypospadias: A cohort study.
Am J Epidemiol 2008 Feb;167(3):251-6. Pubmed abstract

Sverrild A, Backer V, Kyvik KO, Kaprio J, Milman N, Svendsen CB, Thomsen SF.
Heredity in sarcoidosis: A registry-based twin study.
Thorax. 2008 Oct;63(10):894-6. Pubmed abstract

Sørensen HG, van der Deure WM, Hansen PS, Peeters RP, Breteler MM, Kyvik KO, Sørensen TI, Hegedüs L, Visser TJ.
Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes.
Thyroid. 2008 Oct;18(10):1087-94. Pubmed abstract

Taarnhøj NCBB, Munch IC, Sander B, Kessel L, Hougaard JL, Kyvik K, Sørensen TIA, Larsen M.
Straight versus tortuous retinal arteries in relation to blood pressure and genetics.
Br J Ophthalmology 2008 Aug;92(8):1055-60. Pubmed abstract

Thomsen SF, Kyvik KO, Backer V.
Etiological relationships in atopy: A review of twin studies.
Twin Res Hum Genet. 2008 Apr;11(2):112-20. Pubmed abstract

Thomsen SF, Kyvik KO, Backer V.
A note on twin-singleton differences in asthma.
Twin Res Hum Genet. 2008 Apr;11(2):161-4. Pubmed abstract

Thomsen SF, Kyvik KO, Skadhauge LR, Steffensen I, Backer V.
Intake of paracetamol and risk of asthma in adults.
Journal of Asthma 2008 Oct;45 (8): 675-6. Pubmed abstract

Thomsen SF, Stensballe LG, Skytthe A, Kyvik KO, Backer V, Bisgaard H.
Increased concordance of severe respiratory syncytial virus infection in identical twins.
Pediatrics. 2008 Mar;121(3):493-6. Pubmed abstract

van der Deure WM, Hansen PS, Peeters RP, Kyvik KO, Friesema EC, Hegedüs L,Visser TJ.
Thyroid hormone transport and metabolism by organic anion transporter 1C1 and consequences of genetic variation.
Endocrinology. 2008 Oct;149(10):5307-14. Pubmed abstract

Vinberg M, Bennike B, Kyvik KO, Andersen PK, Kessing LV.
Salivary cortisol in unaffected twins discordant for affective disorder.
Psychiatry Research 2008 Dec;161(3): 292-301. Pubmed abstract

2007 -- til toppen --^

Andersen MO, Thomsen K, Kyvik KO.
Adolescent idiopathic scoliosis in twins: A population-based survey.
Spine 2007;32(8):927-30.

Bathum L, Petersen I, Christiansen L, Konieczna A, Sorensen TIA, Kyvik KO.
Genetic and environmental influences on plasma homocysteine - results from a Danish twin study.
Clin Chem. 2007 May;53(5):971-9.

Bendixen A, Sørensen TI, Hørder K, Svendsen AJ, Leboeuf-Yde C, Steffensen IE, Kyvik KO.
Betydningen af fysisk aktivitet og BMI for tilfredshed med kropsbygningen.
[The importance of physical activity and body mass index for body satisfaction (article in Danish)].
Ugeskr Laeger 2007;169(46):3966-70.

Benyamin B, Sørensen TI, Schousboe K, Fenger M, Visscher PM, Kyvik KO.
Are there common genetic and environmental factors behind the endophenotypes associated with the metabolic syndrome?
Diabetologia 2007;50(9):1880-8.

Christensen MV, Kyvik KO, Kessing LV.
Subclinical psychopathology and socio-economic status in unaffected twins discordant for affective disorder.
Journal of Psychiatric Research 2007;41(3-4):229-38.

Christiansen L, Tan Q, Iachina M, Bathum L, Kruse TA, McGue M, Christensen K.
Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population.
Biological Psychiatry 2007; 61(2): 223-30.

Fenger M, Schousboe K, Sørensen TI, Kyvik KO.
Variance decomposition of apolipoproteins and lipids in Danish twins.
Atherosclerosis 2007;191(1):40-7.

Hansen PS, Brix TH, Iachine I, Kyvik KO, Hegedüs L.
Genetic and environmental interrelations between measurements of thyroid function in a healthy Danish twin population.
American Journal of Physiology, Endocrinology and Metabolism 2007;292(3):E765-70.

Hansen PS, van der Deure WM, Peeters RP, Iachine I, Fenger M, Sørensen TI, Kyvik KO, Visser TJ, Hegedüs L.
The impact of a TSH receptor gene polymorphism on thyroid-related phenotypes in a healthy Danish twin population.
Clinical Endocrinology (Oxf.) 2007;66(6):827-32.

Hartvigsen J, Christensen K.
Active lifestyle protects against incident low back pain in seniors. A population-based 2-year prospective study of 1387 Danish twins aged 70-100 years.
Spine 2007;32(1):76-81.

Jørgensen MM, Zachariae R, Skytthe A, Kyvik K.
Genetic and environmental factors in alexithymia: A population-based study of 8,785 Danish twin pairs.
Psychother Psychosom 2007;76(6):369-75.

Kimani JW, Shi M, Daack-Hirsch S, Christensen K, Moretti-Ferreira, Marazita ML, Field LL, Canady JW, Murray JC.
X-chromosome inactivation patterns in monozygotic twins and sib pairs discordant for nonsyndromic cleft lip and/or palate.
American Journal of Medical Genetics Part A, 2007;143(24):3267-72.

Krarup-Andersen F, Christensen K, Frederiksen H.
Self-related health and age. A cross-sectional and longitudinal study of 11,000 Danes aged 45-102.
Scandinavian Journal of Public Health 2007;35(2):164-71.

Lerbaek A, Kyvik KO, Menne T, Agner T.
Retesting with the TRUE Test in a population-based twin cohort with hand eczema - allergies and persistence in an 8-year follow-up study.
Contact Dermatitis 2007; 57(4):248-52.

Lerbaek A, Kyvik KO, Ravn H, Menné T, Agner T.
Incidence of hand eczema in a population-based twin cohort: Genetic and environmental risk factors.
British Journal of Dermatology 2007.

Lerbaek A, Kyvik KO, Mortensen J, Bryld LE, Menné T, Agner T.
Heritability of hand eczema is not explained by co-morbidity with atopic dermatitis.
J Invest Dermatol 2007 Feb 15.

McGue M, Christensen K.
Social activity and healthy aging: A study of aging Danish twins.
Twin Research and Human Genetics 2007;10(2):255-65.

Morales-Suárez-Varela MM, Bech BH, Christensen K, Olsen J.
Coffee and smoking as risk factors of twin pregnancies: the Danish national birth cohort.
Twin Research and Human Genetics 2007;10(4):597-603.

Munch IC, Sander B, Kessel L, Hougaard JL, Taarnhøj NC, Sørensen TI, Kyvik KO, Larsen M.
Heredity of small hard drusen in twins aged 20-46 years.
Investigative Ophthalmology and Visual Science 2007;48(2):833-8.

Osler M, McGue M, Christensen K.
Socioeconomic position and twins’ health: a life-course analysis of 1266 pairs of middle-aged Danish twins.
International Journal of Epidemiology 2007; 36(1):77-83.

Perola M, Sammalisto S, Hiekkalinna T, Martin NG, Visscher PM, Montgomery GW, Benyamin B, Harris JR, Boomsma D, Willemsen G, Hottenga JJ, Christensen K, Kyvik KO, Sørensen TI, Pedersen NL, Magnusson PK, Spector TD, Widen E, Silventionen K, Kaprio J, Palotie A, Peltonen G.
Combined genome scans for body stature in 6,602 European twins: evidence for common caucasian loci.
PLoS Genetics 2007 Jun 8;3(6):e97.

Sørensen GL, Petersen I, Thiel S. Fenger M, Christensen K, Kyvik KO, Sørensen TI, Holmskov U, Jensenius JC.
Genetic influences on mannan-binding lectin (MBL) and mannan-binding lectin associated serine protease-2 (MASP-2).
Genetic Epidemiology 2007;31(1):31-41.

Thomsen SF, Ulrik CS, Kyvik KO, Hjelmborg JB, Skadhauge LR, Steffensen I, Backer V.
Importance of genetic factors in the etiology of atopic dermatitis: a twin study.
Allergy Asthma Proc. 2007 Sep-Oct;28(5):535-9. Pubmed abstract

Thomsen SF, Ulrik CS, Kyvik KO, Sorensen TI, Posthuma D, Skadhauge LR, Steffensen I, Backer V.
Association between obesity and asthma in a twin cohort.
Allergy 2007; 62(10):1199-1204.

Vinberg M, Bech P, Kyvik KO, Kessing LV.
Quality of life in unaffected twins discordant for affective disorder.
Journal of Affective Disorders 2007;99(1-3):133-8.

Vinberg M, Mortensen EL, Kyvik KO, Kessing LV.
Personality traits in unaffected twins discordant for affective disorder.
Acta Psychiatrica Scandinavica 2007;115(6):442-50.

Zhu JL, Basso O, Obel C, Christensen K, Olsen J.
Infertility, infertility treatment and twinning: The Danish National Birth Cohort.
Human Reproduction 2007;4:1086-1090.

2006 -- til toppen --^

Tan Q, Kruse TA, Christensen K.
Design and analysis in genetic studies of human ageing and longevity.
Ageing Research Reviews 2006; 5(4): 371-387.

Skytthe A, Kyvik K, Bathum L, Holm N, Vaupel JW, Christensen K.
The Danish Twin Registry in the New Millennium.
Twin Research and Human Genetics 2006;9(6):763-771.

Frederiksen H, Hjelmborg J, Mortensen J, McGue M, Vaupel JW, Christensen K.
Age trajectories of grip strength: Cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102.
Annals of Epidemiology 2006;16(7):554-62.

Bladbjerg EM, de Maat MPM, Christensen K, Bathum L, Jespersen J, Hjelmborg J.
Genetic influence on thrombotic risk markers in the elderly – a Danish twin study.
J Thromb Haemost 2006;4:599-607.

Brix TH, Hansen PS, Rudbeck AB, Hansen JB, Skytthe A, Kyvik KO, Hegedus L.
Low birth weight is not associated with thyroid autoimmunity. A population based twin study.
J Clin Endocrinol Metab 2006.

Christensen K, Petersen I, Skytthe A, Herskind AM, McGue M, Bingley P.
Comparison of academic performance of twins and singletons in adolescence: A follow-up study.
British Medical Journal 2006; 333(7578):1095-7.

Christensen MV, Kyvik KO, Kessing LV.
Cognitive function in unaffected twins discordant for affective disorder.
Psychol Med 2006;36:1119-29.

Christensen MV, Kyvik KO, Kessing LV.
Subclinical psychopathology and socio-economic status in unaffected twins discordant for affective disorder.
J Psychiatr Res 2006.

Christiansen L, Brasch-Andersen C, Bathum L, Kruse TA, Christensen K.
A longitudinal study of the effect of GSTT1 and GSTM1 gene copy number on survival.
Mech Ageing Dev 2006;127:597-9.

Damborg F, Engell V, Andersen M, Kyvik KO, Thomsen K.
Prevalence, concordance, and heritability of Scheuermann kyphosis based on a study of twins.
J Bone Joint Surg Am 88:2133-6 (2006).

Engell V, Damborg F, Andersen M, Kyvik K, Thomsen K.
Clubfoot – a twin study.
J Bone Joint Surg. 2006;88-B(3):374-6.

Fejer R, Hartvigsen J, Kyvik KO.
Heritability of neck pain: A population-based study of 33,794 Danish twins.
Rheumatology (Oxford) 45:589-94 (2006).

Fejer R, Hartvigsen J, Kyvik KO.
Sex differences in heritability of neck pain.
Twin Res Hum Genet. 2006; 9 (2): 198-204.

Fenger M, Benyamin B, Sørensen TIA, Kyvik KO.
Variance decomposition of apolipoproteins and lipids in Danish twins.
Atherosclerosis. 2006 May 24.

Graakjaer J, Londono-Vallejo JA, Christensen K, Kolvraa S.
The pattern of chromosome-specific variations in telomere length in humans shows signs of heritability and is maintained through life.
Ann N Y Acad Sci 2006;1067:311-6.

Hansen PS, Brix TH, Iachine I, Kyvik KO, Hegedüs L.
The relative importance of genetic and environmental effects for the early stages of thyroid autoimmunity: A study of healthy Danish twins.
Eur J Endocrinol. 2006;154: 29-38.

Hansen PS, Wenzel BE, Brix TH, Hegedüs L.
Yersinia enterocolitica infection does not confer an increased risk of thyroid antibodies: evidence from a Danish twin study.
Clin Exp Immunol 2006; 146(1): 32-8.

Hartvigsen J, Frederiksen H, Christensen K.
Back and neck pain in seniors-prevalence and impact.
Eur Spine J 2006;15:802-6.

Hartvigsen J, Frederiksen H, Christensen K.
Physical and mental function and incident low back pain in seniors: a population-based two-year prospective study of 1387 Danish Twins aged 70 to 100 years.
Spine 2006;31:1628-32.

Hestbaek L, Leboeuf-Yde C, Kyvik KO, Manniche C.
The course of low back pain from adolescence to adulthood: Eight-year follow-up of 9600 twins.
Spine 2006;31:468-72.

Hestbaek L, Leboeuf-Yde C, Kyvik KO.
Are lifestyle-factors in adolescence predictors for adult low back pain? A cross-sectional and prospective study of young twins.
BMC Musculoskeletal Disord 2006;7:27.

Hestbaek L, Leboeuf-Yde C, Kyvik KO.
Is comorbidity in adolescence a predictor for adult low back pain? A prospective study of a young population.
BMC Musculoskeletal Disord 2006;7:29.

Hjelmborg JV, Iachine I, Skytthe A, Vaupel JW, McGue M, Koskenvuo M, Kaprio J, Pedersen NL, Christensen K.
Genetic influence on human lifespan and longevity.
Hum Genet 2006;119:312-21.

Hojlund K, Christiansen C, Bjornsbo KS, Poulsen P, Bathum L, Henriksen JE, Lammert O, Beck-Nielsen H.
Energy expenditure, body composition and insulin response to glucose in male twins discordant for the Trp64Arg polymorphism of the beta3-adrenergic receptor gene.
Diabetes Obes Metab 2006;8:322-30.

Jensen TK, Joffe M, Scheike T, Skytthe A, Gaist D, Petersen I, Christensen K.
Early exposure to smoking and future fecundity among Danish twins.
Int. Journ. of Andrology 2006;29:603-13.

Kohler HP, Rodgers JL, Miller WB, Skytthe A, Christensen K.
Bio-social determinants of fertility.
Int J Androl 2006;29:46-53.

Kyvik KO, Derom C.
Data Collection on Multiple Births – Establishing twin registers and determining zygosity.
Early Hum Dev. 2006 Jun;82(6):357-63

Rexbye H, Petersen I, Johansen M, Klitkou L, Jeune B, Christensen K.
Influence of environmental factors on facial ageing.
Age & Ageing 2006;35:110-5.

Sild M, Koca C, Bendixen MH, Frederiksen H, McGue M, Kolvraa S, Christensen K, Nexo B.
Possible associations between successful aging and polymorphic markers in the Werner gene region.
Ann N Y Acad Sci 2006;1067:309-10.

Silventoinen K, Zdravkovic S, Skytthe A, McCarron P, Herskind AM, Koskenvuo M, de Faire U, Pedersen N, Christensen K, Kaprio J.
Association between height and coronary heart disease mortality: A prospective study of 35,000 twin pairs.
Am J Epidemio 2006;163:615-21.

Singh R, Kolvraa S, Bross P, Christensen K, Gregersen N, Tan Q, Jensen UB, Eiberg H, Rattan SI.
Heat-shock protein 70 genes and human longevity: A view from Denmark.
Ann N Y Acad Sci 2006;1067:301-8.

Sorensen GL, Hjelmborg JB, Kyvik KO, Fenger M, Hoj A, Bendixen C, Sorensen TI, Holmskov U.
Genetic and environmental influences of surfactant protein D serum levels.
Am J Physiol Lung Cell Mol Physiol 2006;290:L1010-L1017.

Storgaard L, Bonde JP, Ernst E, Andersen CY, Spano M, Christensen K, Petersen HC, Olsen J.
Genetic and environmental correlates of semen quality: A twin study.
Epidemiology 2006; 17(6): 674-81.

Stubbe JH, Boomsma DI, Vink JM, Cornes BK, Martin NG, Skytthe A, Kyvik KO, Rose RJ, Kujala UM, Kaprio J, Harris JR, Pedersen NL, Hunkin J, Spector TD, De Geus EJ.
Genetic influences on exercise participation in 37,051 twin pairs from seven countries.
PLoS ONE 1:e22 (2006).

Taarnhøj NCBB, Larsen M, Sander B, Kyvik KO, Kessel L, Hougaard JL, Sørensen TIA.
Heritability of retinal vessel diameters and blood pressure: A twin study.
Invest Ophthalmol.Vis.Sci. 2006;47:3539-44.

Thomsen SF, Ulrik CS, Kyvik KO, Ferreira MA, Backer V.
Multivariate genetic analysis of atopy phenotypes in a selected sample of twins.
Clin Exp Allergy 2006;36:1382-90.

Thomsen SF, Ulrik CS, Kyvik KO, Hjelmborg JV, Skadhauge LR, Steffensen I, Backer V.
Genetic and environmental contributions to hay fever among young adult twins.
Respir Med 2006.

Thomsen SF, Ulrik CS, Kyvik KO, Larsen K, Skadhauge LR, Steffensen I, Backer V.
The incidence of asthma in young adults.
Chest 2005;127:1928-34.

Thomsen SF, Ulrik CS, Kyvik KO, Larsen K, Skadhauge LR, Steffensen IE, Duffy DL, Backer V.
Risk factors for asthma in young adults: A co-twin control study.
Allergy. 2006;61: 229-33.

Tomassini C, Grundy E, Skytthe A, Christensen K.
Twins and their health cost: Consequences of multiple births on parental health and mortality in Denmark and England and Wales.
Twin Res Hum Genet 2006;9:444-9.

2005 -- til toppen --^

Abrahamsen B, Hjelmborg Jv, Kostenuik P, Stilgren LS, Kyvik KO, Adamu S, Brixen K, Langdahl BL.
Circulating amounts of osteoprotegerin and RANK ligand: Genetic influence and relationship with BMD assessed in female twins.
Bone. 2005:36(4): 727-35.

Baker SG, Lichtenstein P, Kaprio J, Holm NV.
Genetic susceptibility to prostate, breast, and colorectal cancer among Nordic twins.
Biometrics 2005;61:55-63.

Basso O, Nohr EA, Olsen J, Christensen K.
Relationship of maternal body mass index and height to twinning.
Obstetrics and Gynecology 2005;106(2):411 (comment/letter).

Bischoff C, Graakjaer J, Petersen HC, Hjelmborg JvB, Vaupel JW, Bohr VA, Koelvraa S, Christensen K.
The heritability of telomere length among the elderly and oldest-old.
Twin Research and Human Genetics 2005;8(5):433-39.

Bischoff C, Graakjaer J, Petersen HC, Jeune B, Bohr VA, Koelvraa S, Christensen K.
Telomere length among the elderly and oldest-old.
Twin Research and Human Genetics 2005;8(5):425-32.

Brix TH, Knudsen GP, Kristiansen M, Kyvik KO, Orstavik KH, Hegedus L.
High frequency of skewed x-chromosome inactivation in females with autoimmune thyroid disease: A possible explanation for the female predisposition to thyroid autoimmunity.
J Clin Endocrinol Metab. 2005 Nov;90(11):5949-53.

Fejer R, Hartvigsen J, Kyvik KO.
Heritability of neck pain: A population-based study of 33,794 Danish twins.
Rheumatology 2005.

Fejer R, Kyvik KO, Hartvigsen J.
The prevalence of neck pain in the world population: A systematic critical review of the literature.
Spine. 2005.

Fibiger S, Tranebjærg L, Skytthe A.
Language, speech, hearing, reading and communication disorders in 35,000 twins born in Denmark 1931-1982.
Proceedings of the 26th World Congress of the International Association of Logopedics and Phoniatrics in Brisbane, Australia, August 2005.

Gaist D, Pedersen L, Madsen C, Tsiropoulos I, Bak S, Sindrup SH, McGue M, Rasmussen BK, Christensen K.
Long-term effects of migraine on cognitive function: A population-based study of Danish twins.
Neurology 2005; 64: 600-7 [Accompanying Editorial Neurology 2005; 64: 590-1].

Hansen PS, Brix TH, Bennedbæk FN, Bonnema SJ, Iachine I, Kyvik KO, Hegedüs L.
The relative importance of genetic and environmental factors in the aetiology of thyroid nodularity: A study of healthy Danish twins.
Clinical Endocrinology 2005; 62: 380-6.

Hansen T, Skytthe A, Stenager E, Petersen HC, Bronnum-Hansen H, Kyvik KO.
Concordance for multiple sclerosis in Danish twins: An update of a nationwide study.
Multiple Sclerosis. 2005;11:504-10.

Hansen T, Skytthe A, Stenager E, Petersen HC, Kyvik KO, Bronnum-Hansen H.
Risk for multiple sclerosis in dizygotic and monozygotic twins.
Multiple Sclerosis. 2005;11:500-3.

Hartvigsen J, Pedersen H C, Frederiksen H, Christensen K.
Small effects of genetic factors on neck pain in old age. A study of 2,108 Danish twins 70 years of age and older.
Spine 2005;30(2):206-8.

Herskind AM, Basso O, Olsen J, Skytthe A, Christensen K.
Is natural twinning rate still declining?
Epidemiology 2005; 16(4):591 (Letter).

Jensen TK, Joffe M, Scheike T, Skytthe A, Gaist D, Christensen K.
Time trends in waiting time to pregnancy among Danish twins.
Human Reproduction 2005;20(4):955-64.

Kjeldsen MJ, Corey LA, Solaas MH, Friis ML, Harris JR, Kyvik KO, Christensen K, Pellock JM.
Genetic factors in seizures: A population-based study of 47,626 US, Norwegian and Danish twin pairs.
Twin Research and Human Genetics 2005;8(2):138-47.

Kristiansen M. Knudsen GP, Bathum L, Naumova AK, Sørensen TI, Brix TH, Svendsen AJ, Christensen K, Kyvik KO, Ørstavik KH.
Twin study of genetic and aging effects on X chromosome inactivation.
European Journal of Human Genetics 2005; 13(5):599-606.

Kyvik KO.
Genetisk ordbog.
Lungeforum. Oktober 2005;03:19-22.

Malis C, Rasmussen EL, Poulsen P, Petersen I, Christensen K, Beck-Nielsen H, Astrup A, Vaag AA.
Total and regional fat distribution is strongly influenced by genetic factors in young and elderly twins.
Obesity Research 2005; 13(12): 2139-45.

Mansilla MA, Kimani, Mitchell LE, Christensen K. et al.
Discordant MZ twins with cleft lip and palate: a model for identifying genes in complex traits.
Twin Research and Human Genetics 2005;8(1):39-46.

Poulsen P, Levin K, Petersen I, Christensen K, Beck-Nielsen H, Vaag A.
Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins.
Diabetes 2005;54(1):275-83.

Rasulo D, Christensen K, Tomassini C.
The influence of social relations on mortality in later life: a study on elderly Danish twins.
The Gerontologist 2005;45(5):601-8.

Rexbye H, Petersen I, Iachina M, Mortensen J, McGue M, Vaupel JW, Christensen K.
Hair loss among elderly men: Etiology and impact on perceived age.
J Gerontol A Biol Sci Med Sci 2005;60:1077-82.

Taarnhoj NC, Munch IC, Kyvik KO, Sander B, Kessel L, Sorensen TIA, Hougaard JL, Larsen M.
Heritability of cilioretinal arteries: A twin study.
IOVS. 2005;46(10):3850-4.

Tan Q, Christensen K, Christiansen L, Frederiksen H, Bathum L, Dahlgaard J, Kruse TA.
Genetic dissection of gene expression observed in whole blood samples of elderly Danish twins.
Human Genetics 2005;117:267-74.

Thomsen SF, Ulrik CS, Kyvik KO, Backer V.
Twin studies of asthma in the Nordic countries.
Lungeforum. Oktober 2005:6-16.

Thomsen SF, Ulrik CS, Kyvik KO, Larsen K, Skadhauge LR, Steffensen I, Backer V.
The incidence of asthma in young adults.
Chest. 2005 Jun;127(6):1928-34.

Tveskov C, Skytthe A, Arnsbo P, Vaupel JW, Moller M, Christensen K.
Twins with implanted pacemakers: Is there an increased mortality risk for the co-twin? A follow-up study based on the Danish Twin Registry and the Danish Pacemaker Register.
Europace 2005; 7(6): 598-603.

Wienke A, Herskind AM, Christensen K, Skytthe A, Yashin AI.
The heritability of CHD mortality in Danish twins after controlling for smoking and BMI.
Twin Research and Human Genetics 2005;8(1):53-9.

2004 -- til toppen --^

Basso O, Nøhr EA, Christensen K, Olsen J.
Risk of twinning as a function of maternal height and body mass index.
JAMA 2004; 291: 1564-6.

Bathum L, Fagnani C, Christiansen L, Christensen K.
Heritability of biochemical kidney markers and relation to survival in the elderly – results from a Danish population-based twin study.
Clinica Chimica Acta 2004; 349: 143-50.

Bathum L, Hjelmborg J, Christiansen L, Madsen JS, Skytthe A, Christensen K.
Evidence for an association of methylene tetrahydrofolate reductase polymorphism C677T and an increased risk of fractures: Results from a population-based Danish twin study.
Osteoporosis International 2004;15:659-64.

Bendixen MH, Nexø BA, Bohr VA, Frederiksen H, McGue M, Kølvraa S, Christensen K.
A polymorphic marker in the first intron of the Werner gene associates with cognitive function in aged Danish twins.
Experimental Gerontology 2004;39:1101-7.

Brix TH, Hansen PS, Kyvik OK, Hegedüs L.
Aggregation of thyroid autoantibodies in first-degree relatives of patients with autoimmune thyroid disease is mainly due to genes: A twin study.
Clin Endocrinol (Oxf) 2004; 60(3): 329-34.

Bryld LE, Hindsberger C, Kyvik KO, Agner T, Menné T.
Genetic factors in nickel allergy evaluated in a population-based female twin sample.
J Invest Dermatol 2004; 123: 1025-9.

Christensen K, Iachina M, Rexbye H, Tomassini C, Frederiksen H, McGue M, Vaupel JW.
"Udseende svarende til alder" - genetik og dødelighed.
["Looking your age" - genetics and mortality (in Danish)].
Ugeskr Laeger 2004 Sep;166(40):3500-1.

Christensen K, Iachina M, Rexbye H, Tomassini C, Frederiksen H, McGue M, Vaupel JW.
Looking old for your age: Genetics and mortality.
Epidemiology 2004; 15: 251-2 (letter).

Graakjaer J, Pascoe L, Der-Sarkissian H, Thomas G, Kølvraa S, Christensen K, Londoño-Vallejo J-A.
The relative lengths of individual telomeres are defined in the zygote and strictly maintained during life.
Aging Cell 2004;3:97-102.

Hansen PS, Brix TH, Bennedbæk FN, Bonnema SJ, Kyvik KO, Hegedüs L.
Genetic and environmental causes of individual differences in thyroid size. A study of healthy Danish twins.
J.Clin.Endocrinol. Metab. 2004; 89: 2071-7.

Hansen PS, Brix TH, Sørensen TIA, Kyvik KO, Hegedüs L.
Genetic influence on the regulation of the pituitary-thyroid axis. A study of healthy Danish twins.
Major JCEM 2004; 89(3): 1181-7.

Hartvigsen J, Christensen K, Frederiksen H, Pedersen HC.
Genetic and environmental contributions to back pain in old age. A study of 2,108 Danish Twins aged 70 and older.
Spine 2004; 29(8): 897-902.

Harvald B, Hauge G, Kyvik KO, Christensen K, Skytthe A, Holm NV.
The Danish Twin Registry: Past and present.
Twin Research 2004; 7(4): 318-35.

Hestbaek L, Iachine IA, Leboeuf-Yde C, Kyvik KO, Manniche C.
Heredety of low back pain in a young population: A classical twin study.
Twin Research 2004; 7(1): 16-26.

Hestbaek L, Leboeuf-Yde C, Kyvik KO, Vach W, Manniche C.
Comorbidity with low back pain. A cross-sectional populationbased survey of 12-22 year olds.
Spine. 2004:29(13);1483-91.

Ilkjaer K, Kortegaard L, Hoerder K, Joergensen J, Kyvik K, Gillberg C.
Personality disorders in a total population twin cohort with eating disorders.
Compr Psychiatry 2004; 45(4): 261-7.

Jensen E, Hyltoft Petersen P, Blaabjerg O, Hansen PS, Brix TH, Kyvik KO, Hegedus L.
Establishment of a serum thyroid stimulating hormone (TSH) reference interval in healthy adults. The importance of environmental factors, including thyroid antibodies.
Clin Chem Lab Med 2004; 42(7): 824-32.

Klaning U, Laursen TM, Licht RW, Kyvik KO, Skytthe A, Mortensen PB.
Is the risk of bipolar disorder in twins equal to the risk in singletons? A nationwide register-based study.
J Affect Disord 2004; 81(2): 141-5.

Laursen M, Bille C, Olesen AW, Hjelmborg J, Skytthe A, Christensen K.
Genetic influence on prolonged gestation: A population-based Danish twin study.
American Journal of Obstetrics and Gynecology 2004; 190: 489-94.

Lorenz D, Frederiksen H, Moises H, Kopper F, Deuschl G, Christensen K.
High concordance for essential tremor in monozygotic twins of old age.
Neurology 2004; 62(2): 208-11.

Rohr G, Kragstrup J, Gaist D, Christensen K.
Genetic and environmental influences on urinary incontinence: A Danish population-based twin study of middle-aged and elderly women.
Acta Obstet Gynecol Scand 2004; 83: 978-82.

Schousboe K, Visscher PM, Erbas B, Kyvik KO, Hopper JL, Henriksen JE, Heitmann BL, Sørensen TIA.
Twin study of genetic and environmental influences on adult body size, shape, and composition.
Int. J. of Obesity 2004; 28: 39-48.

Singh R, Kølvraa S, Bross P, Gregersen N, Andersen Nexø B, Frederiksen H, Christensen K, Rattan SIS.
Association between low self-rated health and heterozygosity for -110A>C polymorphism in the promoter region of HSP70-1 in aged Danish twins.
Biogerontology 2004; 5: 169-76.

Tan Q, De Benedictis G, Yashin AI, Bathum L, Christiansen L, Dahlgaard J, Frizner N, Vach W, Vaupel JW, Christensen K, Kruse TA.
Assessing genetic association with human survival at multiallelic loci.
Biogerontology 2004;4:89-97.

Tan Q, Yashin AI, Christensen K, Jeune B, De Benedictis G, Kruse TA, Vaupel JW.
Multidisciplinary approaches in genetic studies of human aging and longevity.
Current Genomics 2004;5:409-16.

Tan Q, Zhao JH, Hjelmborg J, Vach W, Vaupel JW, Christensen K, Kruse TA.
Power of non-parametric linkage analysis in mapping genes contributing to human longevity in long-lived sib-pairs.
Genetic Epidemiology 2004;26:245-53.

2003 -- til toppen --^

Bryld LE, Hindberger C, Kyvik KO, Agner T, Menné T.
Risk factors influencing the development of hand eczema in a population based twin sample.
Br J Dermatol. 2003 Dec; 149(6): 1214-20.

Christensen K, Frederiksen H, Vaupel JW, McGue M.
Age trajectories of genetic variance in physical functioning: A longitudinal study of Danish twins aged 70 years and older.
Behaviour Genetics 2003;33(2):125-35.

Christensen K, Kohler HP, Basso O, Olsen J, Vaupel JW, Rodgers JL.
The correlation of fecundability among twins: Evidence of a genetic effect on fertility?
Epidemiology 2003;14(1):60-4.

Christensen K, Tomassini, Juel K.
Risk of suicide in twins: Author’s reply.
BMJ 2003; 327: 1169.

Christensen K.
Tvillinger, genetik, miljø og aldring.
[Twins, genetic, environment, and ageing (in Danish)]
Gerontologi og samfund 2003; 19(3): 52-3.

Christiansen L, Frederiksen H, Schousboe K, Skytthe A, Wurmb-Schwark N, Christensen K, Kyvik KO.
Age- and sex-differences in the validity of questionnaire-based zygosity in twins.
Twin Research 2003; 6(4): 275-8.

Evans A, van Baal GCM, McCarron P, de Lange M, Sørensen TIA, de Geus EJC, Kyvik KO, Pedersen NL, Spector TD, Andrew T, Patterson C, Whitfield JB, Zhu G, Martin NG, Kaprio J, Boomsma DI.
The genetics of coronary heart disease: The contribution of twin studies.
Twin Research 2003; 6(5): 432-41.

Frederiksen H, Christensen K.
The influence of genetic factors on physical functioning and exercise in second half of life.
Scand J Med Sci Sports 2003;13(1):9-18.

Frederiksen H, Gaist D, Bathum L, Andersen K, McGue M, Vaupel JW, Christensen K.
Angiotensin I – Converting Enzyme (ACE) gene polymorphism in relation to physical performance, cognition and survival. A follow-up study of elderly Danish Twins.
Annals of Epidemiology 2003;13(1):57-65.

Gaist D, Pedersen NL, Koskenvuo M, Bak S, Giampaoli S, Christensen K, Kaprio J.
Stroke research in GenomEUtwin.
Twin Research 2003; 6(5): 442-7.

Harris JR, Willemsen G, Aitlahti T, Petrini C, Evans A, Silander K, Cirrincione L, Kyvik KO.
Ethical issues and GenomEUtwin.
Twin Research 2003; 6(5): 455-63.

Hartvigsen J, Kyvik KO, Leboeuf-Yde C, Lings S, Bakketeig L.
Ambiguous relation between physical workload and low back pain: A twin control study.
Occup Environ Med. 2003;60:109-14.

Hartvigsen J, Christensen K, Frederiksen H.
Back pain remains a common symptom in old age. A population-based study of 4486 Danish twins aged 70-102.
European Spine Journal, 2003;12:528-34.

Hestbaek L, Leboeuf-Yde C, Kyvik KO, Manniche C.
Is low back pain in youth associated with weight at birth? A cohort study of 8000 Danish adolescents.
Dan Med Bull 2003;50(2):181-5.

Hindsberger C, Bryld LE.
Analysis of twin data ascertained through probands: The double-entry of approach.
Genetic Epidemiology 2003; 25: 225-35.

Hougaard JL, Kessel L, Sander B, Kyvik KO, Sørensen TIA, Larsen M.
Evaluation of heredity as a determinant of retinal nerve fiber layer thickness as measured by optical coherence tomography.
IOVS 2003;44(7):3011-6.

Kessel L, Hougaard JL, Kyvik KO, Sander B, Sørensen TIA, Larsen M.
Corneal fluorescence in relation to genetic and environmental factors: A twin study.
Acta Ophthalmol. Scand. 2003; 81: 508-13.

Kjeldsen MJ, Corey LA, Christensen K, Friis ML.
Epileptic seizures and syndromes in twins: The importance of genetic factors.
Epilepsy Research 2003;55:137-46.

Larsen TB, Sørensen HT, Skytthe A, Johnsen SP, Vaupel JW, Christensen K.
Major genetic susceptibility for venous thromboembolism in men: A study of Danish twins.
Epidemiology 2003;14:328-32.

McGue M, Christensen K.
The heritability of depression symptoms in elderly Danish twins: Occasion-specific versus general effects.
Behaviour Genetics 2003;33(2):83-93.

Mulder EJ, van Baal C, Gaist D, Kallela M, Kaprio J, Svensson DA, Nyholt DR, Martin NG, Macgregor AJ, Cherkas LF, Boomsma DI, Palotie A.
Genetic and environmental influences on migraine: A twin study across six countries.
Twin Research 2003; 6(5): 422-31.

Posthuma D, Beem AL, de Geus EJC, van Baal GCM, von Hjelmborg JB, Iachine I, Boomsma DI.
Theory and practice in quantitative genetics.
Twin Research 2003; 6(5): 361-76.

Silventoinen K, Sammalisto S, Perola M, Boomsma DI, Cornes BK, Davis C, Dunkel L, Lange M, Harris JR, Hjelmborg J, Luciano M, Martin NG, Mortensen J, Nistico L, Pedersen NL, Skytthe A, Spector TD, Stazi MA, Willemsen G, Kaprio J.
Heritability of adult body height: A comparative study of twin cohorts in eight countries.
Twin Research 2003; 6(5): 399-408.

Schousboe K, Visscher PM, Henriksen JE, Hopper JL, Sørensen TIA, Kyvik KO.
Twin study of genetic and environmental influences on glucose tolerance and indices of insulin sensitivity and secretion.
Diabetologia 2003; 46: 1276-83.

Schousboe K, Willemsen G, Kyvik KO, Mortensen J, Boomsma, DI, Cornes BK, Davis CJ, Fagnani C, Hjelmborg J, Kaprio J, de Lange M, Luciano M, Martin NG, Pedersen N, Pietiläinen KH, Rissanen A, Saarni S, Sørensen TIA, van Baal, GCM, Harris JR.
Sex differences in heritability of BMI: A comparative study of results from twin studies in eight countries.
Twin Research 2003; 6(5): 409-21.

Skytthe A, Pedersen NL, Kaprio J, Stazi MA, von Hjelmborg JB, Iachine I, Vaupel JW, Christensen K.
Longevity studies in GenomEUtwin.
Twin Research 2003; 6(5): 448-54.

Tomassini C, Juel K, Holm NV, Skytthe A, Christensen K.
Risk of suicide in twins: 51 year follow up study.
BMJ 2003;327:373-4.

Wienke A, Holm NV, Christensen K, Skytthe A, Juel K, Vaupel JW, Yashin AI.
The heritability of cause-specific mortality: A correlated gamma-frailty model applied to mortality due to respiratory diseases in Danish twins born 1870-1930.
Statistics in Medicine 2003; 22: 3873-87.

2002 ^-- til toppen --^

Bak S, Gaist D, Sindrup SH, Skytthe A, Christensen K.
Genetic liability in stroke. A long-term follow-up study of Danish twins.
Stroke 2002;33:769-74.

Brix TH, Kyvik KO, Hegedüs L.
Association between birth weight and adult disorders in twins: validity of self-reported birth weight.
Twin Research 2002;5(4):308-10.

Christensen K, Gaist D, Vaupel JW, McGue M.
The genetic contribution to rate-of-change in functional abilities among Danish twins aged 75 years and older.
American Journal of Epidemiology 2002;155(2):132-39.

Frederiksen H, Gaist D, Petersen HC, Hjelmborg J, McGue M, Vaupel JW, Christensen K.
Hand grip strength - a phenotype suitable for identifying genetic variants affecting mid- and latelife physical functioning.
Genetic Epidemiology 2002, 23:110-22.

Hjøllund NHI, Storgaard L, Ernst E, Bonde JPE, Christensen K, Olsen J.
Correlation of scrotal temperature in twins.
Human Reproduction 2002;17(7):1837-8.

Iachina M, Jørgensen B, Christensen K, Iachine I.
Analysis of functional abilities for elderly Danish twins using GEE models.
Twin Research 2002,5(4):289-93.

Johnson W, McGue M, Gaist D, Vaupel JW, Christensen K.
Frequency and heritability of depression symptomatology in the second half of life: Evidence from Danish twins over 45.
Psychological Medicine 2002; 32(7):1175-85.

Kessel L, Hougaard JL, Sander B, Kyvik KO, Sørensen TIA, Larsen M.
Lens ageing as an indicator of tissue damage associated with smoking and non-enzymatic glycation – a twin study.
Diabetologia 2002;45:1457-62.

Kjeldsen MJ, Kyvik KO, Friis ML, Christensen K.
Genetic and environmental factors in febrile seizures: A Danish population-based twin study.
Epilepsy Research. 2002;51:167-77.

Kläning U, Pedersen CB, Mortensen PB, Kyvik KO.
A possible association between the genetic predisposition for dizygotic twinning and schizophrenia?
Schizophrenia Research 2002; 58(1): 31-5

Kohler HP, Knudsen LB, Skytthe A, Christensen K.
The fertility pattern of twins and the general population compared: Evidence from Danish cohorts 1945-64.
Demographic Research 2002;6:91-118.

Leboeuf-Yde C, v.Dijk J, Franz C, Hustad SA, Olsen D, Pihl T, Röbech R, Vendrup SS, Bendix T, Kyvik KO.
Motion palpation findings and self-reported low back pain in a population-based study sample.
Journal of Manipulative and Physiological Therapeutics. 2002;25:80-7.

Lyhne N, Sjølie AK, Kyvik KO, Green A.
The importance of genes and environment for ocular refraction and its determiners, a population based study among 20-45 year old twins.
Br J Ophthalmol. 2002;85:1470-6.

McGue M, Christensen K.
The heritability of level and rate-of-change in cognitive functioning in Danish twins aged 70 years and older.
Exp Aging Res. 2002;28(4):435-51.

Petrovsky N, Kyvik KO, Bonnevie-Nielsen V, Beck-Nielsen H, Green A, Harrison LC.
Evidence from twins for acquired cellular immune hyperactivity in type 1 diabetes.
Immunology 2002; 106(4): 584-9.

Rasmussen BB, Brix TH, Kyvik KO, Brøsen K.
The interindividual differences in the caffeine alias CYP1A2 is determined by both genetic and environmental factors.
Pharmacogenetics. 2002;12(6):473-8.

Schousboe K, Henriksen JE, Kyvik KO, Sørensen TIA, Petersen PH.
Reproducibility of S-insulin and B-glucose responses in two identical oral glucose tolerance tests.
Scand J Clin Lab Invest. 2002;62: 623-30.

Skytthe A, Kyvik KO, Holm NV, Vaupel J, Christensen K.
The Danish twin registry: 127 birth cohorts of twins.
Twin Research. 2002;5(5):352-7.

Storgaard L, Bonde JP, Ernst E, Andersen CY, Kyvik KO, Olsen J.
Effect of prenatal exposure to oestrogen on quality of semen: Comparison of twins and singleton brothers.
BMJ. 2002;325:252-3.

Svendsen A, Holm NV, Kyvik KO, Petersen PH, Junker P.
Relative importance of genetic effects in reumatoid arthritis: Historical cohort study of Danish na-tionwide twin population.
BMJ. 2002;324:264-7.

Tan Q, Yashin A, Bladbjerg EM, de Maat MP, Andersen-Ranberg K, Jeune B, Christensen K, James W. Vaupel.
A case-only approach for assessing gene by sex interaction in human longevity. Journal of gerontology.
Biol Sci Med Sci 2002;57: B129-33.

Titlestad IL, Kyvik KO, Kristensen T, Lillevang S.
HLA haplotypes in dizygotic twins more similar than sibs?
Twin Research. 2002;5(4):287-8.

Tomassini C, Rosina A, Billari FC, Skytthe A, Christensen K.
The effect of losing the partner and losing the twin on mortality.
Twin Research 2002;5(3):210-7.

Wienke A, Christensen K, Skytthe A, Yashin AI.
Genetic analysis of cause of death in a mixture model of bivariate lifetime data.
Statistical Modelling 2002;2:1-14.

2001 ^-- til toppen --^

Bathum L, Christiansen L, Nybo H, Andersen-Ranberg K, Gaist D, Jeune B, Petersen NE, Vaupel JW, Christensen K.
Association of mutations in the hemochromatosis gene with shorter life expectancy.
Archives of Internal Medicine 2001;16:2441-4.

Bathum L, Pedersen HC, Rosholm JU, Petersen PH, Vaupel JW, Christensen K.
Evidence for a substantial genetic influence on biochemical liver function test: Results from a population-based Danish twin study.
Clinical Chemistry 2001; 47: 81-7.

Brix TH, Kyvik KO, Christensen K, Hegedüs L.
Evidence for a major role of heredity in Graves’ disease: A population-based study of two Danish cohorts.
J. Clin. Endocrinol. Metab. 2001; 86 (2): 930-4.

Brix TH, Kyvik KO, Hegedüs L.
Validity of self-reported hyperthyroidism and hypothyroidism: Comparison of self-reported questionnaire data with medical record review.
Thyroid 2001; 11 (8): 769-73.

Christensen K, Frederiksen H, Hoffman HJ.
Genetic and environmental influences on self-reported reduced hearing in the old and oldest old.
J.Am.Geriatr.Soc. 01;49(11):1512-7.

Christensen K, Wienke A, Skytthe A, Holm NV, Vaupel J, Yahin AI.
Cardiovascular mortality in twins and the fetal origins hypothesis.
Twin Research. 2001;4:344-9.

Christensen K, Ørstavik K-H, Vaupel JW.
The X chromosome and the female survival advantage: An example of the intersection between genetics, epidemiology and demography.
In: Population Health and Aging: Strengthening the Dialogue Between Epidemiology and Demography.
Annals of the New York Academy of Sciences, 2001 Dec; 954.

De Benedictis G, Tan Q, Jeune B, Christensen K, Ukraintseva SV, Bonafe M, Franceschi C, Vaupel JW, Yashin AI.
Recent advances in human gene-longevity association studies. Viewpoint.
Mechanisms of Ageing and Development 2001;122; 909-20.

Gale EAM, Bingley PJ, Eisenbarth GS, Redondo MJ, Kyvik KO, Petersen JS.
Reanalysis of twin studies suggests that diabetes is mainly genetic.
BMJ 2001; 323: 997.

Kjeldsen MJ, Kyvik KO, Christensen K, Friis ML.
Genetic and environmental factors in epilepsy: A population-based study of 11,900 Danish twin pairs.
Epilepsy Research 44 (2001): 167-78.

Kortegaard LS, Hoerder K, Joergensen J, Gillberg C, Kyvik KO.
Preliminary population-based twin study of self-reported eating disorder.
A Psychol-Med. 2001 Feb; 31(2): 361-5.

Lyhne N, Sjølie AK, Kyvik KO, Green A.
The Importance of Genes and Environment for Ocular Regraction and its Determiners: A Population Based Study Among 20-45 Year Old Twins.
The British Journal of Ophthalmology. 2001; 85(12): 1470-6

McGue M, Christensen K.
The heritability of cognitive functioning in very old adults: Evidence from Danish twins aged 75 and older.
Psychology and Aging 2001;16:272-80.

Poulsen P, Vaag A, Kyvik K, Beck-Nielsen H.
Genetic versus environmental aetiology of the metabolic syndrome among male and female twins.
Diabetologia (2001) 44: 537-43.

Rodgers JL, Kohler HP, Kyvik KO, Christensen K.
Behaviour genetic modeling of human fertility: Findings from a Contemporary Twin Study.
Demography 2001 Feb; 38(1): 29-42.

Tan Q, Yashin AI, Andersen-Ranberg K, Jeune B, Christensen K, Vaupel JW.
Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity
Experimental Gerontology 2001;36:1303-15.

Tomassini C, Billari FC, Rosina A, Christensen K.
Born together - die together. Live together - die together. The role of the partner and of the co-twin on longevity at very old ages.
Genus, 2001, Vol. LVII (3-4):63-82.

Wienke A, Holm NV, Skytthe A, Yashin AI.
The heritability of mortality of heart diseases. A correlated frailty model applied to Danish twins.
Twin Research. 2001;4: 266-74.

2000 ^-- til toppen --^

Basso O, Olsen J, Holm NV, Skytthe A, Vaupel JW, Christensen K.
Handedness and mortality. A follow-up study of Danish twins born between 1900 and 1910.
Epidemiology. 2000 September; 11(5): 576-80.

Bonnevie-Nielsen V, Martensen PM, Justesen J, Kyvik KO, Kristensen B, Levin K, Beck-Nielsen H, Worsaa A, Dyrberg T.
The antiviral 2´,5´-oligoadenylate synthetase is persistently activated in type 1 diabetes.
Clinical Immunology. 2000; 96(1): 11-8.

Brix TH, Hansen PS, Kyvik KO, Hegedüs L.
Cigarette smoking and risk of clinically overt thyroid disease - a population based twin case-control study.
Arch Int Med. 2000; 160: 661-6.

Brix TH, Kyvik KO, Hegedüs L.
A population based study of chronic autoimmune hypothyroidism in Danish twins.
J. Clin. Endocrinol. Metab. 2000; 85: 536-40.

Brix TH, Kyvik KO, Hegedüs L.
Low birth weight is not associated with clinically overt thyroid disease - a population based twin case-control study.
Clinical Endocrinology. 2000; 53: 171-6.

Bryld LE, Agner T, Kyvik KO, Menné T.
Hand Eczema in Twins - a questionnaire investigation.
Br J Dermatology. 2000; 142: 298-305.

Christensen K.
Hvorfor ældes vi forskelligt?
[Why do we age differently?]
Copenhagen: Gyldendal, 2000.

Christensen K, Kristiansen M, Hagen-Larsen H, Skytthe A, Bathum L, Jeune B, Andersen-Ranberg K, Vaupel JW, Ørstavik KH.
X-linked genetic factors regulate hematopoietic stem-cell kinetics in females.
Blood. 2000; 95(7): 2449-51.

Christensen K, McGue M, Yashin AI, Iachine IA, Holm NV, Vaupel JW.
Genetic and Environmental Influence on Functional Abilities Among Danish Twins Aged 75 Years and older.
Journal of Gerontology: Medical Sciences. 2000; 55A(8): M446-52.

Gaist D, Bathum L, Skytthe A, Jensen TK, McGue M, Vaupel JW, Christensen K.
Strength and antropometric measures in identical and fraternal twins: No evidence of masculinization of females with male co-twins.
Epidemiology. 2000 May; 11(3): 340-3.

Harvigsen J, Kyvik KO.
Idiopathic scoliosis in twins studied by DNA finger-printing (letter).
J Bone Joint Surg. 2000; 82-B(2): 308.

Jeanclos E, Schork NJ, Kyvik KO, Kimura M, Aviv A.
Telomere length inversely correlates with pulse pressure and is highly familial.
Hypertension. 2000; 36: 195-200.

Kohler HP, Christensen K.
Genetic influences on fertility behavior: Findings from a Danish twin study.
In: Rodgers JC, Rowe DC and Miller WB (eds.). Genetic Influences on Fertility and Sexuality.
Kluwer Academic Publishers 2000, pp. 67-84.

Kyvik KO, Bache I, Green A, Beck-Nielsen H, Buschard K.
No association between birth weight and Type 1 (insulin dependent) diabetes mellitus. A twin-control study.
Diabetic Medicine. 2000; 17: 158-62.

Lebeuf-Yde C, Kyvik KO.
Is it possible to differentiate people with or without low-back pain on the basis of tests of lumbopelvic dysfunction?
J Manipulative and Physiological Therapeutics. 2000; 23 (3): 160.

Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, Pukkala E, Skytthe A, Hemminki K.
Environmental and heritable factors in the causation of cancer. Analyses of cohorts from Sweden, Denmark, and Finland.
New England Journal of Medicine 2000;343:78-85.

Orholm M, Binder V, Sørensen TIA, Rasmussen LP, Kyvik KO.
Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study.
Scand J Gastroenterol. 2000; 10: 1076-81.

Skadhauge LR, Christensen K, Kyvik KO, Sigsgaard T.
Genetiske og miljømæssige faktorers betydning for asthma. Et populationsbaseret studie af 11.688 danske tvillingpar.
[Significance of genetic and environmental factors for asthma. A population-based study of 11,688 Danish twin pairs (in Danish)]
Ugeskrt for Læger 2000 Jun 26; 162(26): 3726-9. Pubmed abstract

Ulrich V, Gervil M, Kyvik KO, Olesen J, Russell MB.
Betydningen af arv og miljø for migræne med aura. En genetisk epidemiologisk undersøgelse af danske tvillingpar.
[The significance of genetic and environmental factors for migraine with aura. A genetic epidemiologic study of Danish twins (in Danish)]
Ugeskrt for Læger 2000 Jan; 162(2): 167-70. Pubmed abstract

Whiteman DC, Murphy MFG, Verkasalo PK, Page WF, Floderus B, Skytthe A, Holm NV.
Breast cancer risk in male twins: Joint analyses of four twin cohorts in Denmark, Finland, Sweden and the United States.
British Journal of Cancer 2000;83:1231-3.

Wienke A, Christensen K, Holm NV, Yashin AI.
Heritability of death from respiratory diseases: An analysis of Danish twin survival data using a correlated frailty model.
In: Hasman et al. (eds) Medial Infobahn for Europe. Amsterdam, IOS Press 2000: pp. 407-11.

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