J.B. Winsløws Vej 25
5000 Odense C
T: +45 6550 3781
F: +45 3950 3923
Centerkoordinator:
Professor Henrik Ditzel
T: +45 6550 3781
E: hditzel@health.sdu.dk
Secretary:
Anne Marie Bredmose
T: +45 6550 3761
F: +45 6550 3950
E: ambredmose@health.sdu.dk
Research areas
Ditzel group
- Translational biomedical research in cancer
- Breast cancer research with focus on proteomics and transcriptomics
- Predictive and prognostic molecular profiles in breast and lung cancer
- Target discovery
- Structural and functional studies of cancer/testis-associated proteins
- Cancer immunology and autoimmunity with focus on human antibodies isolated by phage display technology
Holmskov group
- Innate immunity and inflammation
- Pattern recognition receptors
- Macrophage biology
- Surfactant protein biology
- Translational biomedical research in inflammation and innate immunity
Owens group
- T lymphocytes and cytokines in CNS inflammation
- Regulation of leukocyte entry to the CNS
- Identification of stimuli for glial cell response to injury and inflammation
- Toll-like receptor expression and function on glial cells
Finsen group
- Microglial responses to acute brain injury
- Neuro-glial interactions in Alzheimers disease
- Molecular and cellular mechanisms of remyelination
Jensen group
- Molecular brain development
- Studies of the molecular genetic specification of projection neuron subtypes in the developing mouse brain
- Characterization of transcription factors controlling pyramidal neuron diversification in the murine and human hippocampus
- Novel techniques for mouse transgenesis (misexpression and knockdown of genes in vivo)
- Studies of Alzheimer's disease pathogenesis in mouse models
Mollenhauer group
- Molecular oncology
- Relationships between infection, inflammation, and cancer and associated pathways
- Epithelial protection/innate defense factors in inflammatory disorders and cancer Inflammatory bowel disease
- Development of new techniques in functional genomics
- Construction of recombinant cancer celle libraries
- High throughput cellular assays
- Systematic identification of novel cancer genes and drug targets
- Functional genomics
- Systems biology
Kassem group (KMEB)
- Studying the molecular mechanisms regulating the differentiation of bone marrow-derived mesenchymal stem cell (hMSC) into osteoblast and adipocyte.
- Studying the mechanisms underlying age-related bone loss diseases.
- Indentifying novel factors regulating bone metabolism.
- Stem cell therapy for bone defect using adipose tissue-derived MSC (AT-hMSC).
- Developing new protocols for tissue engineering for bone regeneration using stem cell.
- Derivation of human embryonic stem cell lines (eESC).
- Direct differentiation of hESC into chondrocyte and osteoblast.